BradycardiaSupraventricular tachycardiasArrhythmiasPSVTNodal conductionCardiacFocal atrial tachycardiaWide-complex tachycardiaRapid rate and severe hypotensionAdenosineMultifocalIntraventricular conductionTreatment of supraventricular tachycardiaReentrantAberrant conductionReentryDyspneaNarrow-complex tachycardiaIncluding Wolff-ParkinsoEffect on atrioventricularSevereAnginaOrthostaticAtrial fibrillationMyocardial infarctionFibrillationEctopicPalpitationsTransientIrregularIntravenousPersistentNodeCardioversionCardiomyopathyIncessantUnstableProcainamide groupOnsetHeart FailureAtrioventricular blockCongenitalManifestations
Bradycardia6
- If, during treatment, heart rate decreases below 50 beats per minute (bpm) at rest or the patient experiences symptoms related to bradycardia such as dizziness, fatigue or hypotension, the dose must be titrated downward including the lowest dose of 2.5 mg twice daily. (medicines.org.uk)
- After two weeks of treatment, the dose can be increased to 7.5 mg twice daily if resting heart rate is persistently above 60 bpm or decreased to 2.5 mg twice daily if resting heart rate is persistently below 50 bpm or in case of symptoms related to bradycardia such as dizziness, fatigue or hypotension. (medicines.org.uk)
- Cardiovascular system: in some cases - bradycardia, hypotension, AV-conduction disturbances, symptoms of heart failure. (medicatione.com)
- Sinus bradycardia and hypotension are the main cardiovascular adverse effects. (pharmacologymentor.com)
- Increased risk of additive bradycardia, conduction disturbances and digoxin toxi. (arogga.com)
- What is bradycardia-tachycardia syndrome? (ecgbuddy.com)
Supraventricular tachycardias4
- The therapeutic benefits of diltiazem in supraventricular tachycardias are related to its ability to slow AV nodal conduction time and prolong AV nodal refractoriness. (nih.gov)
- Treatment of supraventricular tachycardias , including: paroxysmal supraventricular tachycardia, including that associated with accessory conduction pathways (s. de Wolff-Parkinson-White, s. de Lown-Ganong-Levine). (activeingredients.online)
- Adenosine is considered first-line therapy for the investigation and termination of supraventricular tachycardias because of its efficacy and safety . (pharmacologymentor.com)
- Supraventricular tachycardias (SPVT) usually have narrow QRS complexes, but they may be wide because of aberrant counduction through the intraventricular conducting tissue, participation of a bypass tract in the intraventricular depolarization pattern,or in the presence of a coexiting bundle branch block. (rjmatthewsmd.com)
Arrhythmias5
- Surface ECG characteristics of arrhythmias whose underlying mechanism is reentry include 1) paroxysmal onset and cessation, 2) very rapid rates (400 to 500 min -1 possible), and 3) initiation and termination by a premature beat (most often). (vin.com)
- Maintenance of sinus rhythm in patients with supraventricular arrhythmias, including paroxysmal supraventricular tachycardia (PSVT), Wolff-Parkinson-White (WPW) syndrome, junctional ectopic tachycardia, paroxysmal atrial tachycardia, and atrioventricular node re-entrant tachycardia. (pediatriconcall.com)
- Treatment of ventricular arrhythmias, such as sustained ventricular tachycardia. (pediatriconcall.com)
- More seriously, digoxin toxicity can lead to life-threatening arrhythmias, including ventricular tachycardia and ventricular fibrillation. (pharmacologymentor.com)
- For patient education information, see the Heart Health Center , as well as Atrial Flutter , Arrhythmias (Heart Rhythm Disorders) , Stroke , Supraventricular Tachycardia (SVT, PSVT) , and Palpitations . (medscape.com)
PSVT3
- Diltiazem converts paroxysmal supraventricular tachycardia (PSVT) to normal sinus rhythm by interrupting the reentry circuit in AV nodal reentrant tachycardias and reciprocating tachycardias, e.g. (nih.gov)
- F. The most common form of paroxysmal supraventricular tachycardia (PSVT) is AV nodal reentry due to dual pathways of excitation in the region of the AV node (see Figure 1). (rjmatthewsmd.com)
- When there is a disturbance in the normal conduction through the fast pathway, the slow pathway may be activated to conduct the excitation wave to the bundle of His, as well as retrograde back to the fast one, and then back again down the slow pathway continuously to produce the PSVT (see Figure 1). (rjmatthewsmd.com)
Nodal conduction4
- Diltiazem exhibits frequency (use) dependent effects on AV nodal conduction such that it may selectively reduce the heart rate during tachycardias involving the AV node with little or no effect on normal AV nodal conduction at normal heart rates. (nih.gov)
- By slowing down AV nodal conduction, digoxin helps to control the ventricular rate, making it more regular and often slower. (pharmacologymentor.com)
- In summary, while digoxin is primarily used for heart failure, its ability to slow down AV nodal conduction makes it useful as an antiarrhythmic agent in specific cases. (pharmacologymentor.com)
- Inhibits sinoatrial, atrial, and nodal conduction without affecting intraventricular conduction. (bestpharmbuy.com)
Cardiac7
- Re-entrant atrial tachycardia is usually seen after cardiac surgery or catheter ablation with linear lesions that result in islets of scars. (medscape.com)
- Mechanisms of arrhythmogenesis primarily include disorders of cardiac electrical impulse formation and electrical impulse conduction. (vin.com)
- Tachyarrhythmia is used to describe tachycardia in the presence of cardiac rhythm abnormality. (mims.com)
- While class I antiarrhythmic drugs are effective in treating this form of tachycardia, there is a reluctance to use these agents, especially in patients with structural heart disease, because of potential proarrhythmia or undesirable side effects-as seen in the cardiac arrhythmia suppression trial (CAST). (bmj.com)
- The cardiac effects are specific to the sinus node with no effect on intra-atrial, atrioventricular or intraventricular conduction times, nor on myocardial contractility or ventricular repolarisation. (azurewebsites.net)
- This cardiac rhythm occurs due to improper electrical conduction within the heart that disrupts the coordination of heartbeats. (aclsonline.us)
- It is categorized as a Vaughn-Williams Class IC agent based upon its properties of causes a strong degree of sodium channel blockage with slowing cardiac conduction and a minimal effect on ventricular repolarization. (encyclopedia.pub)
Focal atrial tachycardia4
- In clinical practice, three major types of atrial tachycardia are seen: focal atrial tachycardia, multifocal atrial tachycardia (MAT), and re-entrant atrial tachycardia. (medscape.com)
- Focal atrial tachycardia arises from a localized atrial site and is characterized by regular, organized atrial activity with discrete P waves and, typically, an isoelectric segment between P waves. (medscape.com)
- Focal atrial tachycardia is usually episodic or paroxysmal. (medscape.com)
- Weber R, Letsas KP, Arentz T, Kalusche D. Adenosine sensitive focal atrial tachycardia originating from the non-coronary aortic cusp. (medscape.com)
Wide-complex tachycardia1
- [ 1 ] It was touted as the drug of choice for treating wide complex tachycardia (WCT) of various types, especially for monomorphic ventricular tachycardia (VT). (medscape.com)
Rapid rate and severe hypotension1
- A rapid rate and severe hypotension may lead to syncope. (medscape.com)
Adenosine1
- Adenosine is antiarrhythmic agent that is widely used for the investigation and management of both narrow complex and, less often, broad complex tachycardias. (pharmacologymentor.com)
Multifocal1
- In patients with multifocal atrial tachycardia (MAT), the history may disclose an underlying illness that is causing the tachycardia. (medscape.com)
Intraventricular conduction1
- Verapamil HCl does not alter the normal atrial action potential or intraventricular conduction time, but depresses amplitude, velocity of depolarization and conduction in depressed atrial fibers. (drugs.com)
Treatment of supraventricular tachycardia2
- Pharmacological treatment of supraventricular tachycardia remains a common approach despite the increased use of radiofrequency ablation. (bmj.com)
- Treatment of supraventricular tachycardia (documented) with the aim of slowing the rhythm of ventricular contractions or restoring sinus rhythm during atrial fibrillation and flutter. (bestpharmbuy.com)
Reentrant3
- Reentrant atrial tachycardia is not uncommon in patients with a history of a surgically repaired atrial septal defect. (medscape.com)
- Slowing down of conduction at the AV node can disrupt the timing of reentrant circuits, restoring patients to normal heart (sinus) rhythms. (pixorize.com)
- Atrial tachycardia due to enhanced automaticity may be nonsustained but repetitive or it may be continuous or sustained, as in reentrant forms of atrial tachycardia. (medscape.com)
Aberrant conduction1
- The exact diagnosis (eg, VT vs supraventricular tachycardia with aberrant conduction) was not the focus of the study, given that in real-world scenarios the real diagnosis is typically uncertain, and no ECG criteria have been found to be reliable in this distinction. (medscape.com)
Reentry1
- 2) Paroxysmal supraventricular tachycardia- it's a arrhythmia due to reentry phenomenon taking place at SA or AV node. (pharmanotes.org)
Dyspnea1
Narrow-complex tachycardia1
- Typical ECG findings with SVT include narrow-complex tachycardia, electrical alternans, evidence of atrial activation (P', F, or f waves), and response to treatments that slow down AV conduction. (vin.com)
Including Wolff-Parkinso1
- Supraventricular tachycardia (heart rhythm disorder), including Wolff-Parkinson-White syndrome (congenital heart disease characterized by recurrent disorders of heart rhythm and rate) paroxysmal form of atrial fluttering, ventricular tachycardia. (otcantabuse.com)
Effect on atrioventricular1
- Because of its selective class III antiarrhythmic effect, dofetilide has no effect on atrioventricular conduction or sinus node function. (bmj.com)
Severe3
- Also in injectable: severe hypotension, severe CHF, ventricular tachycardia (except verapamil-sensitive), AMI, patients receiving ß-adrenergic blockers. (activeingredients.online)
- Unstable patients are those with ongoing chest pain, severe shortness of breath, altered level of consciousness, or hypotension. (medscape.com)
- New onset AF associated with severe hypotension, pulmonary edema, and angina can be managed with electrical cardioversion. (drbeen.com)
Angina3
- These include: coronary artery disease, angina, paroxysmal tachycardia and Wolff-Parkinson-White syndrome. (wikipedia.org)
- Signs and symptoms related to rapid heart rate are altered sensorium, angina, shortness of breath, myocardial infarction, hypotension and other signs of shock (eg cold clammy skin, low urine output), heart failure or pulmonary congestion. (mims.com)
- Verapamil is an active ingredient used for the treatment of S upraventricular Tachycardias, Atrial Tachycardia, High Blood Pressure and Angina . (activeingredients.online)
Orthostatic1
- It may cause you to feel lightheaded or weak especially when you stand up (orthostatic hypotension). (arogga.com)
Atrial fibrillation3
- Atrial fibrillation / atrial flutter with variable AV conduction AND accessory pathway (e.g. (wikem.org)
- Control of patients with flutter and/or chronic atrial fibrillation , except when associated with the existence of accessory conduction pathways (s. de Wolff-Parkinson-White, s. de Lown-Ganong-Levine). (activeingredients.online)
- Flecainide is an IC antiarrhythmic drug approved in 1984 from Food and Drug Administration for the suppression of sustained ventricular tachycardia and later for acute cardioversion of atrial fibrillation (AF) and for sinus rhythm maintenance. (encyclopedia.pub)
Myocardial infarction1
- Whether or not a rhythm-control strategy is adopted, adequate rate control should be achieved in all patients with AF to prevent myocardial infarction (if significant coronary artery disease is present), exacerbation of heart failure, and tachycardia-induced cardiomyopathy and to alleviate symptoms. (ahrq.gov)
Fibrillation3
- Pacerone (amiodarone HCl) is an antiarrhythmic drug indicated for treatment of recurrent ventricular fibrillation and recurrent hemodynamically unstable ventricular tachycardia only when these conditions have not responded to documented adequate doses of other available antiarrhythmics or when alternative agents could not be tolerated. (rxlist.com)
- Atrial flutter or fibrillation, except when associated with the existence of accessory conduction pathways (s. de Wolff-Parkinson-White, s. de Lown-Ganong-Levine). (activeingredients.online)
- 2. Paroxysmal atrial flutter or fibrillation. (rjmatthewsmd.com)
Ectopic2
- Conduction abnormalities may result in delayed conduction or block, but may also contribute to the formation of ectopy (premature or ectopic depolarizations). (vin.com)
- The antiarrhythmic effect of this medicine is due to the elimination of arrhythmogenic factors (tachycardia, increased activity of the sympathetic nervous system, increase of cAMP, hypertension), decrease in the rate of spontaneous excitation of the sinus and ectopic pacemakers and slowing of AV conduction. (medicatione.com)
Palpitations1
- Typically, atrial tachycardia manifests as a sudden onset of palpitations. (medscape.com)
Transient1
- Patients who are taking other treatments for their symptoms (e.g. beta blockers and nifedipine) have developed minor transient conduction defects when given Prajmaline. (wikipedia.org)
Irregular3
- MAT is an irregular supraventricular tachycardia characterized by three distinct P-wave morphologies and/or patterns of atrial activation at different rates. (medscape.com)
- The rate is usually regular, but it may be irregular in rapid atrial tachycardias with variable AV conduction and in MAT. (medscape.com)
- Medications given for an irregular heart rate associated with tachycardia include those that help control heart rate and restore a normal heart rhythm. (medicinenet.com)
Intravenous3
- OBJECTIVE To assess the efficacy and safety of intravenous dofetilide in preventing induction of atrioventricular re-entrant tachycardia. (bmj.com)
- RESULTS Intravenous dofetilide had no effect on tachycardia inducibility at the two lower doses (1.5 and 3 μg/kg) but prevented the reinduction of tachycardia at the three higher doses (6, 9, and 15 μg/kg) at a rate of 36% (11/31). (bmj.com)
- Our goal in this study was to assess the efficacy of intravenous dofetilide, in five different dosing regimens, for treating patients with inducible atrioventricular re-entrant tachycardia, by determining its ability to prevent reinduction of the tachycardia. (bmj.com)
Persistent2
- Paroxysmal, persistent, permanent. (drbeen.com)
- It is estimated that more than 2.3 million Americans have paroxysmal or persistent AF. (ahrq.gov)
Node8
- It has no effect on the sinus node recovery time or on the sinoatrial conduction time in patients without SA nodal dysfunction. (nih.gov)
- Supraventricular tachycardia (SVT) is an arrhythmia initiated above the ventricles, at or above the atrioventricular (AV) node. (aclsonline.us)
- In terms of its antiarrhythmic effects, digoxin slows down the conduction of electrical impulses through the atrioventricular (AV) node. (pharmacologymentor.com)
- Because the AV node cannot conduct at the same rate as the atrial activity, some form of conduction block is often seen, typically 2:1 (most common), 3:1, or 4:1. (medscape.com)
- When we talk about disorders of the sinus node, it is important to know the following terms that are all expressed by a pathological sinus node: sinus node syndrome, sick sinus syndrome, sinus node dysfunction, sinus node disease, sinu-atrial disease, and bradycardia-tachycardia syndrome. (ecgbuddy.com)
- This disease often manifests itself not only in the sinus node, but also in the other parts of the conduction system such as the AV node or the Tawara branches. (ecgbuddy.com)
- As we learned earlier, the prerequisites for the formation of a P wave are depolarization of the sinus node and the successful conduction of this excitation into the atrial myocardium. (ecgbuddy.com)
- When conduction from the sinus node to the atrial myocardium is delayed or impaired, we call this sinus node block or sinuatrial block. (ecgbuddy.com)
Cardioversion1
- Flecainide was first synthesized in 1972 and approved in 1984 from the Food and Drug Administration (FDA) for the suppression of sustained ventricular tachycardia [ 1 ] and later for acute cardioversion of AF and for sinus rhythm maintenance. (encyclopedia.pub)
Cardiomyopathy2
- Re-entrant atrial tachycardias are usually incessant and may lead to cardiomyopathy. (medscape.com)
- Not only is the risk of death in patients with AF twice that of patients without AF, but AF can result in myocardial ischemia or even infarction, heart failure exacerbation, and tachycardia-induced cardiomyopathy if the ventricular rate is not well-controlled. (ahrq.gov)
Incessant1
- Treatment related side effects were reported in four patients, one with a new sustained incessant supraventricular tachycardia. (bmj.com)
Unstable1
- In the event of breakthrough episodes of VF or hemodynamically unstable VT, Give 150-mg/100 ml D5W over 10 minutes to minimize potential for hypotension. (globalrph.com)
Procainamide group1
- Tachycardia termination occurred in 11 (38%) in the amiodarone group and 22 (67%) in the procainamide group. (medscape.com)
Onset1
- Atrial tachycardia may gradually speed up soon after its onset ("warm-up" phenomenon) and gradually slows down before termination ("cool-off" phenomenon). (medscape.com)
Heart Failure1
- If frequent episodes of supraventricular tachycardia occur over time and go untreated, the heart may become weakened, contributing to the development of heart failure. (aclsonline.us)
Atrioventricular block2
- Note also that the tachycardia persists despite the atrioventricular block. (medscape.com)
- Atrioventricular block can occur in patients without preexisting conduction defects. (drugs.com)
Congenital1
- In addition to individuals with heart diseases, including congenital heart disease, atrial tachycardia may also occur in persons with structurally normal hearts. (medscape.com)
Manifestations1
- Autonomic and hormonal input modulate multiple facets of cellular electrophysiology - action potential duration, ion channel kinetics and intracellular calcium dynamics (just to name a few) - which translate into macroscopic manifestations of autonomic modulation such as heart rate variability, atrioventricular (AV) conduction time and QT interval variability. (aerjournal.com)