Conclusions axotomy. Medical search. Frequent questions

However, baseline opening of K ATP channels and their activation induced by metabolic inhibition was suppressed by axotomy. (biomedcentral.com)

Methods: Using Sprague-Dawley rats, retinal ganglion cell damage was induced by either intravitreal administration of NMDA or optic nerve axotomy. (elsevierpure.com)

Return of function in eye closure, blinking reflex, and vibrissae movements were assessed and compared to control groups through 30 days following axotomy. (biomedcentral.com)
Ten days after the optic nerve axotomy, the number of surviving RGC was significantly increased even at a dose of 0.3 pmol (815±239 cells/mm 2 , P=0.0359) compared with control (462±75 cells/mm 2 ). (elsevierpure.com)

Background: To investigate the neuroprotective effect of intravitreal administration of latanoprost on retinal ganglion cell (RGC) damage induced by N-methyl-D-aspartic acid (NMDA) or optic nerve axotomy. (elsevierpure.com)
Co nclusions: Intravitreal administration of latanoprost has a neuroprotective effect on rat RGC damage induced by either NMDA or optic nerve axotomy, while its pharmacological features are different. (elsevierpure.com)

The comparability of AI in animal models to human diffuse AI (DAI) is discussed and the conclusion drawn that, although animal models allow the analysis of morphologic changes, the spatial distribution within the brain and the time course of reactive axonal change differs to some extent both between species and with the mode of brain injury. (nih.gov)

Conclusions The chromatin response of cells to unexpected perturbations is considerably quicker, nuanced and complicated than previously explained. (researchensemble.com)

Conclusion: Our study demonstrates that GIRK3 is expressed in sensory neurons and spinal cord. (uib.no)
When developing experimental strategies, other factors have to be considered, such as axotomy-induced cell death and secondary degeneration (Schwartz, 2004a), scar formation (Rhodes and Fawcett, 2004), and factors intrinsic to neurons themselves. (org.es)
In marked contrast, axotomy rapidly transformed damaged neurons into just two new and closely-related classes where almost all original identity was lost. (nih.gov)

The presence of these inclusions does not correlate with signs of axonal and neuronal degeneration, and axotomy leads to their gradual disappearance, indicating that they represent reversible structures. (biomedcentral.com)
Seems to prevent the degeneration of motor axons after axotomy. (prospecbio.com)

There was a suggestion that retinal axons could regenerate after axotomy if the cut optic nerve end was anastomosed to a sciatic nerve graft (Tello, 1907). (org.es)

Besides, there was a loss of neuronal MHC-I expression, which is necessary for balanced synaptic stripping after axotomy. (unizar.es)

Methods: A sciatic nerve axotomy was performed to study the influences of injury on GIRK3 expression in DRGs and spinal cord. (uib.no)
In conclusion, this study represents a novel role of piR-DQ541777 in the regulation of neuropathic pain through the methylation of cdk5rap1 . (jneurosci.org)

In conclusion, our in vivo imaging results showed that new olig2 + cells were born from mOLs by asymmetric division in adult zebrafish, which highlights the role of mOLs in the progression of remyelination in the mammalian CNS. (springeropen.com)

Recently, we have characterized the expression of GIRK1 and − 2, and both are downregulated in rat DRGs and spinal cord after a complete sciatic nerve transection (axotomy). (uib.no)