• We highlight key questions that serologic studies can help answer at different times, review strengths and limitations of different assay types and study designs, and discuss methods for rapid sharing and analysis of serologic data to determine global transmission of severe acute respiratory syndrome coronavirus 2. (cdc.gov)
  • Discussion on the use of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) serologic studies has largely focused on 2 questions: first, what proportion of a population has been infected? (cdc.gov)
  • We estimated the population prevalence of antibodies to severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), including unreported infections, through a Seroprevalence Study of Monitoring of SARS-CoV-2 Antibody Retention and Transmission (K-SMART) in 258 communities throughout Korea. (e-epih.org)
  • Multiplex PCR in this study showed admissible sensitivity and specificity for the detection of E. histolytica , G. intestinalis , and Cryptosporidium spp. (ac.ir)
  • The K-SMART represents the first nationwide, community-based seroepidemiologic survey of COVID-19, confirming that most individuals possess antibodies to SARS-CoV-2 and that a significant number of unreported cases existed. (e-epih.org)
  • Seroprevalence of Anti-SARS-CoV-2 IgG Antibodies in Geneva, Switzerland (SEROCoV-POP): A Population-Based Study. (acc.org)
  • Over the course of the study, 219 of 2,766 tested positive for SARS-CoV-2 IgG antibodies. (acc.org)
  • The study estimates 1 in 10 people have developed detectable antibodies against SARS-CoV-2 in Switzerland. (acc.org)
  • With some studies reporting a rapid loss of antibodies weeks after exposure to SARS-CoV-2, the seroprevalence might be an underestimate of the true exposure. (acc.org)
  • The only published study on HAV seroprevalence was reported in 1976-1978 when about 84% of samples were positive for HAV-specific antibodies. (who.int)
  • This study was to explore to explore the outcomes of IgG antibodies to SARS-CoV-2 in four groups of individuals in Wuhan, China. (researchgate.net)
  • Conclusions Very few healthcare providers had IgG antibodies to SARS-CoV-2, though a significant proportion of them had been infected with the virus. (researchgate.net)
  • This information is in contrast to a study in Wuhan, China that found 10% of patients lost SARS-CoV-2 antibodies within weeks of infection (12) , although different serology tests were used in this case. (researchgate.net)
  • We therefore conducted a nested case-control study of lung cancer within a longitudinal study to assess antibodies to MCV, KIV, WUV, and eight HPV types, using liquid bead microarray antibody (LBMA) assays. (imacst.com)
  • Background: The between-and within-herd variability of porcine reproductive and respiratory syndrome virus (PRRSV) antibodies were investigated in a cross-sectional study of 103 British pig herds conducted 2003-2004. (birmingham.ac.uk)
  • The association between the prevalence of antibodies against Kaposi's sarcoma-associated herpesvirus (KSHV or human herpesvirus 8 [HHV-8]) and sociodemographic, sexual, reproductive and lifestyle factors was investigated in a study of adults presenting with cancer at hospitals in Kampala, Uganda. (richarddollconsortium.org)
  • In conclusion, in this population in Uganda, where KSHV is relatively common, the prevalence of anti-KSHV antibodies increased with age but showed little association with nearly 50 other factors studied. (richarddollconsortium.org)
  • MATERIAL AND METHODS: After full census of the study population, 651 participants were interviewed, clinically examined and had a blood sample taken for the detection of malaria parasites (microscopy and PCR) and antibodies against P. vivax (PvMSP119, PvAMA1) and P. falciparum (PfGLURP, PfAMA1) antigens by ELISA. (itg.be)
  • Methods and Results- We analyzed enrollment sera from 3168 Canadian patients in the Heart Outcomes Prevention Evaluation (HOPE) study for antibodies to C pneumoniae , H pylori , CMV, and HAV and measured the relation between serostatus and 494 adjudicated trial outcomes of myocardial infarction, stroke, or CV death over 4.5 years of follow-up. (mcmaster.ca)
  • This study was undertaken to (1) assess the presence of maternally acquired measles-specific IgG antibodies among infants less than 9 months of age in Bangui, Central African Republic and (2) determine the immune status of vaccination-age children and the concordance with reported vaccination status. (hal.science)
  • This was a cross-sectional study using the data collected from a nationwide survey between November and December 2022 to explore factors associated with hesitancy towards coronavirus disease 2019 (COVID-19) vaccination for children. (bvsalud.org)
  • The objective of this study was to identify the most suitable vaccination strategy for controlling the surge in COVID-19 cases. (e-epih.org)
  • In a potential epidemic of an emerging infection, representative population-based serologic studies are required to determine the extent of immunity to the infectious agent, either from natural infection or vaccination. (biomedcentral.com)
  • In the context of a possible epidemic, where public health response and planning, policy decisions and pandemic preparedness strategies are required, population-based, longitudinal serologic studies are necessary, both to determine the extent of immunity - either naturally acquired or from vaccination-and to evaluate the pace of infection and immunity acquisition [ 2 , 3 ]. (biomedcentral.com)
  • ABSTRACT A cross-sectional seroepidemiological study was conducted in the Rabat-Salé-Zemmour-Zaër region of Morocco in 2007 among 267 barbers and 529 clients, all men with no history of hepatitis B (HBV) vaccination. (who.int)
  • METHODS: In this study, we present the results of a serological screening of the healthcare workers (HCWs) on a ward for infectious diseases in Sweden with a point-of-care antibody test 8 weeks after an outbreak of COVID-19. (lu.se)
  • Methods Participants (n=5158, aged 15-59 years) were included from three independent nationwide population-based serosurveillance studies in 1996, 2007 and 2017. (bmj.com)
  • METHODS: This nationwide population-based study included adults aged ≥20 years who received a prescription of oral FQ or third-generation cephalosporins (3GC) during outpatient visits from 2005 to 2016. (bvsalud.org)
  • Methods Population studies with sample size of at least 500 and published as peer-reviewed papers or preprints as of May 12, 2020 were retrieved from PubMed, preprint servers, and communications with experts. (researchgate.net)
  • Patients and Methods: A cross-sectional study was performed on 1563 randomly selected individuals from general population of Mashhad, Iran, between May and September 2009. (razavihospital.ir)
  • METHODS: We conducted a nested case-control study of 8,126 participants in a consortium of 10 prospective cohorts in the United States. (duke.edu)
  • Furthermore, this study lays the foundation for a surveillance system to continuously monitor transmission at the community level and the response to COVID-19. (e-epih.org)
  • 10. Rastogi M, Rastogi D, Singh S, Agarwal A, Priyadarshi BP, Middh T: Prevalence of Helicobacter pylori in asymptomatic adult patients in a tertiary care hospital: A cross sectional study. (iabcr.org)
  • First, for infections that elicit detectable antibody responses, serologic studies can detect past infection regardless of clinical symptoms. (cdc.gov)
  • This capability is useful for understanding the extent of past transmission ( Figure 1 , panel A). By linking this information with data on symptomatic cases, severe disease, and death in the same population, these studies can provide information on asymptomatic proportion, and the ratio of infections to severe cases and deaths (i.e., infection fatality ratio). (cdc.gov)
  • The aim of this study was to establish a relationship between the incidence of cataract and evidence of bacterial infections transmitted by ticks. (medscimonit.com)
  • Serological studies have shown that infections caused by B. burgdorferi sensu lato and Bartonella sp. (medscimonit.com)
  • Men who provide traditional viral RNA for confirmation of HCV infections are a serious global public barber services were identified and en- infection. (who.int)
  • Conclusions Prior infections with some of various kinds HPyV or HPV had not been associated with following medical diagnosis of lung cancers. (imacst.com)
  • That is a restriction because, unlike nucleic acidity amplification check (NAAT) based research, potential seroepidemiologic research could probably detect the association of infections that initiate carcinogenesis, but whose viral DNA is simply no detectable in the tumors. (imacst.com)
  • Seroepidemiology of hepatitis A virus infections in Over 6-years population in Isfahan-Iran: A community-based study. (razavihospital.ir)
  • This study evaluated the annual fluctuations in chigger mite populations and Orientia tsutsugamushi infections in South Korea. (ophrp.org)
  • Over half of these infections are estimated to have occurred during the study period and the incidence of infection in late October 2009 was estimated at 4.3 new infections per 1000 people per day (1.2 to 7.2), falling close to zero by April 2010. (ox.ac.uk)
  • Conclusions- Exposure to CMV but not to C pneumoniae , H pylori , or HAV was associated with a slight excess risk of subsequent myocardial infarction, stroke, or CV death in HOPE study patients, and total pathogen score based on these infections predicted a small increased hazard of CV events. (mcmaster.ca)
  • Second, if measured antibody responses correlate with protection, serologic studies can be used to measure the proportion of the population that is immune. (cdc.gov)
  • CONCLUSIONS: Prediagnostic antibody responses to F. nucleatum proteins were not associated with the risk of colorectal cancer. (duke.edu)
  • This study highlights the value of rapid, onboard diagnostic testing to quickly identify an outbreak and enumerate cases, as well as the serological testing to flag potential cases missed with standard viral case identification methodologies. (health.mil)
  • CONCLUSIONS: Our results indicate that a serological follow-up screening after an outbreak may be used as a complement to virus detection in an outbreak situation. (lu.se)
  • CONCLUSION: The use of a single parasitological and serological malaria survey has proven to be an efficient and accurate method to characterize the species specific heterogeneity in malaria transmission at micro-geographical level as well as to identify recent changes in transmission. (itg.be)
  • A national cross-sectional study among drug-users in France: epidemiology of HCV and highlight on practical and statistical aspects of the design. (hal.science)
  • BACKGROUND: Epidemiology of HCV infection among drug users (DUs) has been widely studied. (hal.science)
  • CONCLUSIONS: The unique data set collected in this study highlights how regional epidemiology data for HBV can provide insights into patterns of transmission, and it provides an evidence base for future quantitative research into the most effective local interventions. (ox.ac.uk)
  • Serologic studies are crucial for clarifying dynamics of the coronavirus disease pandemic. (cdc.gov)
  • Past work on serologic studies (e.g., during influenza pandemics) has made relevant contributions, but specific conditions of the current situation require adaptation. (cdc.gov)
  • Successful deployment of serologic studies depends on type and performance of serologic tests, population studied, use of adequate study designs, and appropriate analysis and interpretation of data. (cdc.gov)
  • Serologic studies are crucial for understanding current and future dynamics of the coronavirus disease (COVID-19) pandemic. (cdc.gov)
  • In the past few months, much discussion about serologic studies and key issues with their design and interpretation has occurred. (cdc.gov)
  • Objective To estimate the infection fatality rate of coronavirus disease 2019 (COVID-19) from data of seroprevalence studies. (researchgate.net)
  • Estimates of infection fatality rates inferred from seroprevalence studies tend to be much lower than original speculations made in the early days of the pandemic. (researchgate.net)
  • Seroprevalence studies provide an accurate measure of SARS-CoV-2 spread and the presence of asymptomatic cases. (biomedcentral.com)
  • Thus, seroprevalence studies identify the infection burden in communities leading to more appropriate control measures for local epidemic expansion. (biomedcentral.com)
  • This is the earliest documented COVID-19 study with RT-PCR, serology, and pre-exposure test data on the entirety of the exposed population (n=333). (health.mil)
  • Exposure to HAV infection in patients with chronic liver disease in Italy, a multicentre study. (razavihospital.ir)
  • Recent studies provided evidence on the relationship between social status and exposure patterns, the likelihood of diagnosis, and infection outcomes for COVID-19 in Santiago. (biomedcentral.com)
  • Fancourt D, Steptoe A, Bu F. Trajectories of anxiety and depressive symptoms during enforced isolation due to COVID-19 in England: a longitudinal observational study. (smw.ch)
  • This study included 12,296,756 samples of the max share of the sub-lineages from the 33rd week of 2020 to the 40th week of 2022. (bvsalud.org)
  • Quantitative, descriptive, cross-sectional study conducted in the last months of 2020. (bvsalud.org)
  • This study suggests that Borrelia burgdor- patient became seropositive, confi rmed by WB (Figure 1, feri infection is in Mexico. (cdc.gov)
  • In all, 107/123 (87%) of HCWs who were tested with RT-PCR in the outbreak investigation participated in this study on seroprevalence. (lu.se)
  • The study area for this investigation is Ba subdivision, an agricultural centre situated on the north-western side of Viti Levu, Fiji's main island. (who.int)
  • This study aimed to establish the prevalence of H. pylori infection in symptomatic patients and its relationship with various risk factors specially smoking, alcohol and socioeconomic status. (iabcr.org)
  • A prospective cross-sectional study was done in symptomatic patients undergoing gastroduodenoscopy, to assess the prevalence of H. pylori and its associated risk factors in a tertiary care hospital of South Delhi. (iabcr.org)
  • This study aims to provide a descriptive analysis of hepatitis B virus (HBV) and hepatitis C virus (HCV) seroprevalence of blood donations in Haiti. (cdc.gov)
  • The differentiation of hepatitis A, then called infectious hepatitis, from hepatitis B, then called serum hepatitis, came principally from studies in volunteers in Europe and the United States from the 1940s through the 1960s. (nationalacademies.org)
  • Seroprevalence and risk factors of hepatitis A virus infection in Iran: a population based study. (razavihospital.ir)
  • Taghavi SA, Hosseini Asl MK, Talebzadeh M, Eshraghian A. Seroprevalence study of hepatitis A virus in Fars province, southern Iran. (razavihospital.ir)
  • General epidemiological parameters of viral hepatitis A, B, C, and E in six regions of China: a cross-sectional study in 2007. (razavihospital.ir)
  • The SEROCoV-POP study is a population-based study of former participants of the Bus Santé study and their household members. (acc.org)
  • After inviting 6,229 participants of the Bus Santé study, the authors enrolled 2,834 in SEROCoV-POP, of whom 2,766 had complete data. (acc.org)
  • We identified 96 studies representing 39 African countries, with a median cohort size of 370 participants and a median participant age of 34 years. (ox.ac.uk)
  • In conclusion, the presence of viral antigen in lung tissues of sheep may indicate that natural pneumonia may be induced by BHV1 or possibly other species-specific herpesviruses. (ac.ir)
  • The objective of this study was to investigate the presence of religiosity/spirituality among the Brazilian population facing the pandemic of COVID-19, correlated with quality of life. (bvsalud.org)
  • A secondary objective was to describe the presence of rubella-specific IgG antibody in the study population. (hal.science)
  • CONCLUSIONS: We estimate that almost half the adult population of Scotland were sero-positive for A/H1N1 2009 influenza by early 2010 and that the majority of these individuals (except in the oldest age classes) sero-converted as a result of natural infection with A/H1N1 2009. (ox.ac.uk)
  • This study conducted a two-state Markov-switching model to estimate the probability of the phase shift state and predicted the probability of each regime with the Hamilton filter and Kim's smoothing algorithm. (bvsalud.org)
  • Using pooled data from the 2001-2002 and 2013-2014 Medical Expenditure Panel Survey for each definition, this study conducted in 2017 used multivariate logistic regression to estimate changes in preventive dental care use among children from low-income families by race/ethnicity. (cdc.gov)
  • CONCLUSION: This is the first time that blood testing combined to GWSM is applied to a DUs population, which improve the estimate of HCV prevalence. (hal.science)
  • Il s'agit d'une étude transversale, monocentrique et descriptive, durant 12 mois, incluant les patients âgés d'au moins 18 ans admis en réanimation polyvalente pour un sepsis ou choc septique. (bvsalud.org)
  • This was a cross-sectional, monocentric and descriptive study, lasting 12 months, including patients aged at least 18 years admitted to ICU for sepsis or septic shock. (bvsalud.org)
  • CONCLUSIONS AND CLINICAL RELEVANCE: Serosurvey in dogs was found to be ineffective in tracking early invasion dynamics of I scapularis in this area. (tamu.edu)
  • POTENTIAL RELEVANCE: This study demonstrates relationships between conformation and musculoskeletal disease in the racehorse. (equine-behaviour.de)
  • The K-SEROSMART represents the first nationwide, community-based seroepidemiologic survey of COVID-19. (e-epih.org)
  • Association between maternal haemoglobin concentrations and maternal and neonatal outcomes: the prospective, observational, multinational, INTERBIO-21st fetal study. (the-incubator.org)
  • Within a seroepidemiologic study to determine the true burden of SARS-CoV2 infection in two Bay Area counties, we evaluated whether letter (L) or postcard (P) invitations with reminders were more effective at recruiting participant households. (biomedcentral.com)
  • We implemented a series of seroepidemiologic studies to determine the true burden of SARS-CoV2 infection in two Bay Area counties in California, and anticipated that response rates to an unsolicited invitation to participate in serologic testing for SARS-CoV2 would likely have a better response than that typical for unsolicited mailings, purported to range from 2.7% to 4.4% [ 13 ]. (biomedcentral.com)
  • The studies were assessed for design features and seroprevalence estimates. (researchgate.net)
  • In 2004-2005, we conducted a national seroepidemiologic survey of DUs, based on a random sampling design using the Generalised Weight Share Method (GWSM) and on blood testing. (hal.science)
  • Diarrhoeal disease, May 2017, http://www.who.int/mediacentre/factsheets/fs330/en/ . (ac.ir)
  • Studies on blood donors were included, but studies on healthcare workers were excluded. (researchgate.net)
  • Infection rates are similar in both sexes, though some studies have noted a slight male predominance [2]. (webmedcentral.com)
  • Conclusions: HSV-2 infection is highly endemic in Guanacaste, even among lifetime monogamous women, suggesting a role of male behaviour in the transmission of the infection. (elsevierpure.com)
  • Overall, each model has its advantages and disadvantages and is differentially suited for studies of dengue pathogenesis and immunopathogenesis and/or pre-clinical testing of antiviral drugs and vaccines. (mdpi.com)
  • The study is constrained by gaps in the published data, such that we could not model the impact of antiviral therapy based on stratification by specific clinical criteria and our model framework does not include explicit age-specific or risk-group assumptions regarding force of transmission. (ox.ac.uk)
  • The present study was undertaken to investigate this. (nih.gov)
  • Predicated NCT-501 on this carcinogenic potential in the respiratory system, prior studies possess wanted to judge the association between lung HPV and cancer infection. (imacst.com)
  • Results Twelve studies were identified with usable data to enter into calculations. (researchgate.net)
  • Prevalence and sociobehavioural data among DUs are therefore available in most countries but no study has taken into account in the sampling weights one important aspect of the way of life of DUs, namely that they can use one or more specialized services during the study period. (hal.science)
  • A total of 70 patients with upper gastrointestinal symptoms were included in the study. (iabcr.org)
  • The objective of this study was to isolate a Brucella lon mutant and to analyze the cytokine response of B. lon mutant during macrophage infection. (ophrp.org)
  • The objective of the present study was to perform CSF ferritin analytical validation. (bvsalud.org)
  • Objective: to evaluate the association of the risk classification categories with the Modified Early Warning Score and the outcomes of COVID-19 patients in the emergency service Method: a crosssectional study carried out with 372 patients hospitalized with a COVID-19 diagnosis and treated at the Risk Classification Welcoming area from the Emergency Room. (bvsalud.org)
  • This study aimed to investigate the risk of AA/AD associated with FQ use. (bvsalud.org)
  • Conclusions The infection fatality rate of COVID-19 can vary substantially across different locations and this may reflect differences in population age structure and case-mix of infected and deceased patients as well as multiple other factors. (researchgate.net)
  • The aim of the study was to describe the course of patients with sepsis and/or septic shock in the polyvalent ICU of the University Teaching Hospital of Brazzaville. (bvsalud.org)
  • Sixteen patients (ten with one or more intestinal fistula) developed abdominal wall dehiscence were included in this study. (who.int)
  • This study estimated the nationwide, age- and area-adjusted anti-HAV prevalence from 2005 to 2009. (e-cmh.org)
  • We believe that our study makes a significant contribution to the field because it proposes a new approach for forecasting the ongoing pandemic, and the spread of other infectious diseases, using a statistical model which incorporates unpredictable factors such as human behavior, political factors, and cultural beliefs. (bvsalud.org)
  • To your knowledge, there were simply no seroepidemiologic NCT-501 studies from the association between polyomavirus lung and infection cancer. (imacst.com)
  • The main goal of this study was to determine Bovine Herpes virus type 1 BHV1antigen in formalin-fixed paraffin-embedded lung tissue of pneumonic sheep, using immunohistochemistry (IHC) staining method. (ac.ir)
  • In this article, we discuss the questions that could be answered with these studies at different points in the epidemic and summarize the features and issues regarding study design, implementation of studies during an ongoing epidemic, and interpretation of the results. (cdc.gov)
  • Results: Results obtained from this study showed prevalenceof 87.9% and 7.8% for IgG and IgM respectively. (brighton.ac.uk)
  • RESULTS: The overall parasite prevalence by PCR was low, i.e. 3.9% for P. vivax and 6.7% for P. falciparum, while the seroprevalence was substantially higher, 33.6% for P. vivax and 22.0% for P. falciparum, with major differences between study sites. (itg.be)
  • RESULTS: Of horses included in the study, 56.4% showed sand in the faeces and 5.7% had more than 5 mm sand as quantified by the rectal sleeve sedimentation test. (equine-behaviour.de)
  • Socio-economic factors and the outcomes of this seroprevalence study enable us to identify priority areas for intervention. (biomedcentral.com)
  • IMPACT: Future studies may consider a more specific detection of the immunoglobulin isotypes or focus on examining F. nucleatum in stool or tissue samples. (duke.edu)
  • REASONS FOR PERFORMING STUDY: The relationship of conformation to future potential injury is a standard approach in practise but, at present, is largely based on subjective observations. (equine-behaviour.de)
  • STUDY DESIGN: Serial cross-sectional national surveys. (cdc.gov)
  • This study had two main objectives: to determine the seroprevalence of syphilis in a cohort of 37,210 first time blood donors and to study socio-demographic factors associated with the risk of infection by Treponema pallidum. (elsevierpure.com)
  • The Bus Santé is a study of a yearly sample of the Geneva canton population that includes 500 men and 500 women who fill standardized questionnaires covering risk factors for chronic diseases, sociodemographic, occupational, and educational histories. (acc.org)
  • REASONS FOR PERFORMING STUDY: Sandy soil is often mentioned as a risk factor in the development of sand-related gastrointestinal disease (SGID) in the horse. (equine-behaviour.de)
  • CONCLUSION: To evaluate the risk of sand intake it is important to consider 3 variables: soil type, pasture quality and feeding practice. (equine-behaviour.de)