• It was described by József Mátyás Baló who initially named it "leuko-encephalitis periaxialis concentrica" from the previous definition, and it is currently considered one of the borderline forms of multiple sclerosis. (wikipedia.org)
  • Baló's concentric sclerosis is a demyelinating disease similar to standard multiple sclerosis, but with the particularity that the demyelinated tissues form concentric layers. (wikipedia.org)
  • Scientists used to believe that the prognosis was similar to Marburg multiple sclerosis, but now they know that patients can survive, or even have spontaneous remission and asymptomatic cases. (wikipedia.org)
  • Balo concentric sclerosis is now believed to be a variant of pattern III multiple sclerosis and probably due to metabolic problems. (wikipedia.org)
  • Balò's concentric sclerosis : still to be considered as a variant of multiple sclerosis? (unimi.it)
  • Balò's concentric sclerosis (BCS) is considered a rare demyelinating disease and regarded as an aggressive variant of multiple sclerosis (MS). We describe three cases (one male and two females) with neuroimaging features suggestive of BCS and heterogeneous symptoms, with benign long-term clinical course upon treatment with natalizumab and fingolimod. (unimi.it)
  • What is multiple sclerosis? (nih.gov)
  • Multiple sclerosis (MS) is the most common disabling neurological disease of young adults with symptom onset generally occurring between the ages of 20 to 40 years. (nih.gov)
  • The term multiple sclerosis refers to the distinctive areas of scar tissue (sclerosis-also called plaques or lesions) that result from the attack on myelin by the immune system. (nih.gov)
  • Multiple sclerosis (MS) is an immune-mediated inflammatory disease that attacks myelinated axons in the central nervous system, destroying the myelin and the axon in variable degrees and producing significant physical disability within 20-25 years in more than 30% of patients. (medscape.com)
  • MRI of the head of a 35-year-old man with relapsing-remitting multiple sclerosis. (medscape.com)
  • The FDA has approved alemtuzumab for relapsing forms of multiple sclerosis. (medscape.com)
  • Ghadge VV, Bondre AG, Parate TR, Bhiwgade RD. Marburg variant of multiple sclerosis: A case report. (vjim.org)
  • Multiple sclerosis (MS) is a demyelinating disorder with central nervous system (CNS) involvement, leading to varied presentations. (vjim.org)
  • They are sometimes considered different diseases from Multiple Sclerosis, [4] [5] but considered by others to form a spectrum differing only in terms of chronicity, severity, and clinical course. (mdwiki.org)
  • Multiple sclerosis for some people is a syndrome more than a single disease. (mdwiki.org)
  • Anti-MOG associated spectrum , often clinically presented as an anti- MOG autoimmune encephalomyelitis , [21] [22] but can also appear as negative NMO or atypical multiple sclerosis. (mdwiki.org)
  • Some anti- neurofascin demyelinating diseases were previously considered a subtype of Multiple Sclerosis but now they are considered a separate entity, as it happened before to anti-MOG and anti-AQP4 cases. (mdwiki.org)
  • The last two decades have seen a dramatic increase in the research of treatments and treatment strategies for children with MS. However, to date, there are no approved medications in the US or EU for the treatment of multiple sclerosis in children, because no phase III medication trials have been completed in the pediatric MS population. (ipmssg.org)
  • Recent literature on multiple sclerosis (MS) demonstrates the growing implementation of optical coherence tomography-angiography (OCT-A) to discover potential qualitative and quantitative changes in the retina and optic nerve. (biomedcentral.com)
  • Multiple sclerosis (MS) is an inflammatory auto-immune disease causing demyelination and axonal loss in the central nervous system (CNS) with varying geographical prevalence and incidence rates [ 1 , 2 ]. (biomedcentral.com)
  • Harford's clients range from triathletes, professional sailors and marathon runners to people suffering from multiple sclerosis, plantar fasciitis and other ailments like neck, hip, shoulder, back, knee pain and migraine headaches. (stellarstrength.com)
  • I would suggest also trying one act a day, each and every day, as author Cami Walker did as she was struggling with multiple sclerosis, chronicled in her book 29 Gifts . (pentareddyn.com)
  • There are several other factors besides age that can accelerate the onset of presbyopia, including eye injury, diseases such as diabetes or multiple sclerosis, drug use, gender (women tend to get it at a younger age than men), and occupation (if your job requires a lot of close up work, presbyopia may occur sooner). (healthgymbeauty.com)
  • We'll also get an update on the tale of a wayward piece of space junk soon to impact the moon, and dive into the link between Epstein-Barr virus and multiple sclerosis. (sciencefriday.com)
  • Balo-like lesions have been reported in aquaporin-4 seropositive and seronegative NMOSD, and also in children, as part of an ADEM-like presentation Lesions under MRI are distinctive due to their natural concentric shape. (wikipedia.org)
  • Concentric sclerosis of Balo is differentiated from diffuse cerebral sclerosis of Schilder by the pathologic finding of alternating bands of destruction and preservation of myelin in concentric rings. (sdsu.edu)
  • Balo's concentric sclerosis causes concentric rings of myelin destruction that can be seen on an MRI and is another variant type of MS that can progress rapidly. (nih.gov)
  • The concentric ring appearance is not specific to Baló's MS. Concentric lesions have also been reported in patients with neuromyelitis optica, standard MS, progressive multifocal leukoencephalopathy, cerebral autosomal dominant arteriopathy with subcortical infarcts, leukoencephalopathy, concomitant active hepatitis C and human herpes virus 6. (wikipedia.org)
  • The lesions of the Baló's sclerosis belong to the MS lesion pattern III (distal oligodendrogliopathy). (wikipedia.org)
  • citation needed] Under a lumbar puncture CSF test, with Baló's concentric sclerosis, as well as patients with pattern III lesions, were recently shown to be mostly negative for CSF-restricted oligoclonal bands. (wikipedia.org)
  • Diffuse Cerebral Sclerosis of Schilder" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings) . (sdsu.edu)
  • This graph shows the total number of publications written about "Diffuse Cerebral Sclerosis of Schilder" by people in this website by year, and whether "Diffuse Cerebral Sclerosis of Schilder" was a major or minor topic of these publications. (sdsu.edu)
  • Below are the most recent publications written about "Diffuse Cerebral Sclerosis of Schilder" by people in Profiles. (sdsu.edu)
  • The present study is an examination of possible subclinical involvement of lower motor neuron (LMN) in patients with primary lateral sclerosis (PLS) and hereditary spastic paraparesis (HSP) electrophysiologically. (hspersunite.org.au)
  • According with Dr. Lucchinetti investigations, in Baló's concentric sclerosis, the rings may be caused by a physiological hypoxia (similar to that caused by some toxins or viruses) in the lesion, which is in turn countered by expression of stress proteins at the border. (wikipedia.org)
  • Hence, subsequent attacks form concentric rings. (wikipedia.org)
  • All patients showed the typical MRI changes associated with BCS, such as concentric rings or a whorled appearance on T2-weighted and contrast-enhanced T1-weighted images. (unimi.it)
  • Fundus autofluo-rescence showed an array of lobules and specks of hypoautofluorescence arranged in concentric rings in the macula of both eyes (as shown in Fig. 2 of the right eye). (aao.org)
  • These unusual dou-ble concentric autofluorescence rings have been described with NR2E3 mutations. (aao.org)
  • When diagnosing Lyme disease, most doctors look for the "bulls-eye rash"-called the erythema migrans (EM) rash, with concentric rings surrounding a red center-but only 70 to 80 percent of patients develop it. (loveysmarket.com)
  • Also pattern III patients tend to be negative under the MRZ-reaction (measles, rubeola and zoster viruses) Baló's concentric sclerosis in children has been reported to behave different from adults A report comparing 1H-magnetic resonance spectroscopy, magnetization transfer and diffusion tensor imaging with histopathology in a patient with Baló's concentric sclerosis, found that inflammation was traced by fractional anisotropy and increased lactate. (wikipedia.org)
  • Signs of tubular atrophy, interstitial fibrosis, and interlobular sclerosis were noted. (biomedcentral.com)
  • Ki-Hara uses concentric and eccentric movements to strengthen and stretch muscle tissues. (stellarstrength.com)
  • Jitter measurement with concentric needle electrode (25 mm, 30 G) (CN-jitter) recorded from right extensor digitorum muscle during voluntary contraction with 1 kHz high-pass frequency filter set. (hspersunite.org.au)
  • EMG uses a concentric needle to record the electrical activity produced by skeletal muscles and yields very important diagnostic information. (utswmed.org)
  • It was a way of getting inside what Peggy just called those concentric circles, and really having an impact on, we hope, on the incidence of the disease in the region. (sciencefriday.com)
  • In others, called concentric, one type of correction is found in the middle of the contact lens, while the other kind of correction encircles it around the outside of the lens. (healthgymbeauty.com)
  • Baló's concentric sclerosis is a disease in which the white matter of the brain appears damaged in concentric layers, leaving the axis cylinder intact. (wikipedia.org)
  • Histologically EAF is characterised by the presence of mixed inflammatory cells with eosinophil predominance in the early stage, followed by concentric layers of sclerosis around the small caliber vessels in the late stage. (ijmedicine.com)
  • CSF-restricted oligoclonal bands are present only in a minority of cases A mathematical model for concentric sclerosis has been proposed. (wikipedia.org)
  • Authors review the previous pathogenic theories, discuss the link between concentric sclerosis and Liesegang's periodic precipitation phenomenon and propose a new mechanism based on self-organization. (wikipedia.org)
  • At that time, the echocardiography showed concentric left ventricular hypertrophy (LVH) (ejection fraction 64 %) and an abdominal ultrasound showed no abnormalities. (biomedcentral.com)
  • 5. Baló's concentric sclerosis: surviving normal myelin in a patient with a relapsing-remitting dinical course. (nih.gov)
  • Balo's concentric sclerosis causes concentric rings of myelin destruction that can be seen on an MRI and is another variant type of MS that can progress rapidly. (nih.gov)
  • A common misconception is that any attack of CNS demyelination means a diagnosis of acute multiple sclerosis (MS). When a patient has a first attack of demyelination, the physician should not rush to diagnose MS, because the differential diagnosis includes a number of other diseases. (medscape.com)
  • 9. Marburg type and Balò's concentric sclerosis: rare and acute variants of multiple sclerosis. (nih.gov)
  • Baló's concentric sclerosis is a demyelinating disease similar to standard multiple sclerosis, but with the particularity that the demyelinated tissues form concentric layers. (wikipedia.org)
  • Hence, subsequent attacks form concentric rings. (wikipedia.org)
  • Scientists used to believe that the prognosis was similar to Marburg multiple sclerosis, but now they know that patients can survive, or even have spontaneous remission and asymptomatic cases. (wikipedia.org)
  • It was described by József Mátyás Baló who initially named it "leuko-encephalitis periaxialis concentrica" from the previous definition, and it is currently considered one of the borderline forms of multiple sclerosis. (wikipedia.org)
  • 8. Exploring the overlap between multiple sclerosis, tumefactive demyelination and Baló's concentric sclerosis. (nih.gov)
  • 14. Concentric MR patterns in multiple sclerosis. (nih.gov)
  • Multiple Sclerosis (MS) -MS affects the central nervous system that disrupts the flow of information within the brain, and between the brain and body. (outsourcestrategies.com)
  • What is multiple sclerosis? (nih.gov)
  • Multiple sclerosis (MS) is the most common disabling neurological disease of young adults with symptom onset generally occurring between the ages of 20 to 40 years. (nih.gov)
  • Idiopathic inflammatory demyelinating diseases (IIDDs) are considered to be borderline variants of multiple sclerosis or are considered by others to be a spectrum of diseases which vary in their clinical course or severity. (manchesterneurophysio.co.uk)
  • Epstein-Barr virus (EBV) has been implicated in the pathogenesis of multiple sclerosis (MS). Recent reports proposed an increased EBV-targeted humoral immune response in MS, which appears to be more pronounced in pediatric patients. (springer.com)
  • Jarius S, Würthwein C, Behrens JR, Wanner J, Haas J, Paul F, Wildemann B. Baló's concentric sclerosis is immunologically distinct from multiple sclerosis: results from retrospective analysis of almost 150 lumbar punctures. (legehandboka.no)
  • Vitamin D and multiple sclerosis. (ac.ir)
  • Multiple sclerosis (MS) is a chronic demyelinating disease and also is one of the most common disabling neurological disorders in young and middle-aged adults. (ac.ir)
  • Level of attitude toward complementary and alternative medicine among Iranian patients with multiple sclerosis. (ac.ir)
  • Background: Multiple sclerosis (MS) is an unpredictable neurological disease leading to severe disability in young adults. (ac.ir)
  • In this paper, we used prospectively-acquired data from 112 multiple sclerosis (MS) patients and 15 healthy volunteers (HV) to assess the performance and optimize outcomes of a Level Test. (nih.gov)
  • Mitoxantrone , also known as mitozantrone , is a medication used to treat cancer and multiple sclerosis . (mdwiki.org)
  • 3. [Antemortem diagnosis of Balo's concentric sclerosis based on MRI. (nih.gov)
  • 15. [Contribution of proton magnetic resonance spectroscopy to the diagnosis of Balo's concentric sclerosis]. (nih.gov)
  • 19. Balo's concentric sclerosis: value of magnetic resonance imaging in diagnosis. (nih.gov)
  • The objective is to report a 24-year-old female patient with Baló's concentric sclerosis and its difficult diagnosis. (bctrims2023.com.br)
  • The diagnosis of systemic sclerosis is based on the clinical manifestations. (medscape.com)
  • 18. Balo's concentric sclerosis: a clinical case study of brain MRI, biopsy, and proton magnetic resonance spectroscopic findings. (nih.gov)
  • Clinical and Radiologic Features, Pathology, and Treatment of Baló Concentric Sclerosis. (legehandboka.no)
  • 11. Baló's concentric sclerosis: imaging findings and pathological correlation. (nih.gov)
  • Conventional radiography is the principal imaging study for assessment of gastrointestinal involvement in systemic sclerosis. (medscape.com)
  • Colonoscopy can identify wide-mouth colonic diverticula, which are uniquely characteristic for systemic sclerosis. (medscape.com)
  • Pulmonary function testing is important in all patients with systemic sclerosis, although lung volumes may correlate poorly with the extent of interstitial lung disease. (medscape.com)
  • Also pattern III patients tend to be negative under the MRZ-reaction (measles, rubeola and zoster viruses) Baló's concentric sclerosis in children has been reported to behave different from adults A report comparing 1H-magnetic resonance spectroscopy, magnetization transfer and diffusion tensor imaging with histopathology in a patient with Baló's concentric sclerosis, found that inflammation was traced by fractional anisotropy and increased lactate. (wikipedia.org)
  • If patients with SCD crisis are being transported by emergency medical services (EMS), they should receive supplemental oxygen and intravenous hydration en route to the hospital. (medscape.com)
  • When diagnosing Lyme disease, most doctors look for the "bulls-eye rash"-called the erythema migrans (EM) rash, with concentric rings surrounding a red center-but only 70 to 80 percent of patients develop it. (sunspotnatural.com)
  • According with Dr. Lucchinetti investigations, in Baló's concentric sclerosis, the rings may be caused by a physiological hypoxia (similar to that caused by some toxins or viruses) in the lesion, which is in turn countered by expression of stress proteins at the border. (wikipedia.org)
  • Cite this: Baló's Concentric Sclerosis Presenting as a Stroke-like Syndrome - Medscape - Jun 01, 2007. (medscape.com)
  • Xie JS, Jeeva-Patel T, Margolin E. Baló's concentric sclerosis - A rare entity within the spectrum of demyelinating diseases. (legehandboka.no)
  • Baló concentric sclerosis is often associated with more inflammatory cerebrospinal fluid (CSF) findings and a more fulminant progression than typical MS. (medscape.com)
  • Baló's concentric sclerosis is a disease in which the white matter of the brain appears damaged in concentric layers, leaving the axis cylinder intact. (wikipedia.org)
  • 2. Balo's concentric sclerosis diagnosed intravitam on brain biopsy. (nih.gov)
  • Authors review the previous pathogenic theories, discuss the link between concentric sclerosis and Liesegang's periodic precipitation phenomenon and propose a new mechanism based on self-organization. (wikipedia.org)
  • 13. [Balò's concentric sclerosis in a North-African patient]. (nih.gov)
  • 6. Balo's concentric sclerosis: an update and comprehensive literature review. (nih.gov)
  • Normal development of the hip joint requires a concentric relationship of the femoral head and acetabulum. (musculoskeletalkey.com)