Concentrations dna binding proteins. Medical search. Frequent questions

The Rap proteins are, in turn, inhibited by their cognate Phr peptides, which are produced as pre-Phr proteins that are exported to the extracellular milieu and cleaved to produce mature five to six amino acid Phr peptides. (nature.com)
The Phr peptides are imported back into the cell upon reaching threshold concentrations at high cell density and bind to their cognate Rap phosphatase, inducing conformational changes that inhibit its activity 10 , 11 . (nature.com)
Sulfur mustard is an alkylating agent which quickly reacts with nucleophiles such as DNA, RNA, water, lipids, peptides, and proteins via an episulfonium ion intermediate. (cdc.gov)

Because my protein is a DNA binding protein, I think that I lost some proteins fixed on genomic DNA that are found in the pellet during the step of clarification just after breaking cells. (bio.net)
The activation of replication checkpoint may slow down DNA replication and improve DNA replication fidelity, which increases the maintenance of genomic stability and counteracts carcinogenesis. (nih.gov)
By using published DNA binding specificity data for five transcription factors active in the early Drosophila embryo, genomic regions containing unusually high concentrations of predicted binding sites were identified for these factors. (sdbonline.org)
Using CIS-ANALYST, the distribution of Bcd, Cad, Hb, Kr, and Kni binding sites were examined in a 1-Mb genomic region surrounding the well-characterized eve locus at a site_p value of 0.0003. (sdbonline.org)
Signal intensity was not affected by genomic DNA when present in equal mass to the target DNA. (nebraska.edu)
Biotech Europe GmbH, Freiburg, Germa- cation of the virus in cells heterozygous for ny) was used to extract genomic DNA the mutation proceeded at an intermediate from white blood cells following the lysis rate [ 5 ]. (who.int)

The objective of the present work was to establish the association between DNA damage, the energetic metabolism and the effects of the generation of oxygen free radicals in middle gluteal muscle of horses, measured after a severe exercise bout on a treadmill. (scielo.org.ar)
It regulates GENETIC TRANSCRIPTION involved in METABOLISM of AMINO ACIDS in response to the increased concentration of LEUCINE. (bvsalud.org)
THs enhance oxygen consumption of most body tissues and increase the basal metabolic rate and metabolism of carbohydrates, lipids, and proteins, thus exerting a profound influence on every organ system. (medscape.com)

The effects of dermatotoxic chemicals on activator protein (AP1) DNA binding activity and c-jun and c-fos messenger RNA (mRNA) levels were examined in normal human epidermal keratinocytes. (cdc.gov)
Other blocking agents such as inert proteins or mRNA can reduce background binding in low-input ChIP, without contaminating the data 2 . (abcam.com)
Our results suggest that an aberrant DNA methylation of GATA3 and TGF-β is associated with their mRNA expression and participates in the pathogenesis of BD. (oncotarget.com)
Receptor binding leads to activation or repression of DNA transcription, thereby altering the amounts of mRNA and resultant proteins. (pediatriconcall.com)
The reactivated phage takes apart the host's DNA and produces large amounts of its own mRNA , so as to produce prodigious amounts of phage units. (wikidoc.org)

The involvement of viral DNA-binding proteins in the regulation of virulence genes, transcription, DNA replication, and repair make them significant targets. (mdpi.com)
KIN17, which is known as a DNA and RNA binding protein, is highly expressed in numerous types of human cancers and was discovered to participate in several vital cell behaviors, including DNA replication, damage repair, regulation of cell cycle and RNA processing. (spandidos-publications.com)
Previous studies have indicated that KIN17 is involved in global genome repair, DNA replication, transcription and regulation of the cell cycle as part of a multi-protein complex. (spandidos-publications.com)
This is a heavy metal coordination complex that exerts its cytotoxic effect by platination of DNA, a mechanism analogous to alkylation, leading to interstrand and intrastrand DNA crosslinks and inhibition of DNA replication. (medscape.com)
DNA adducts are quickly repaired, or DNA synthesis is blocked to avoid further replication of the mutation. (cdc.gov)

The authors conclude that dermatotoxic chemical exposure increases the AP1 DNA binding activity and the stimulation of early/immediate genes. (cdc.gov)
Sequences of previously described binding sites were collected for these five factors present in the cis-regulatory regions of known target genes. (sdbonline.org)
Overall, when she began working in this lab with Wieschaus she discovered new ways of working on recombinant DNA and molecular biology with the focus to clone developmentally interesting genes. (wepapers.com)
In the following paragraphs, we will write genes in italics and their associated proteins in Roman. (wikidoc.org)
At high concentration of cI, transcriptions of both genes are repressed. (wikidoc.org)
Conclusions Manifestation of multiple genes encoding epigenetic factors is associated with drug response and with DNA methylation of numerous epigenome focuses on that may impact response to restorative agents. (edrc2013.org)
Products of TET methylcytosine dioxygenase genes (and (and participate in DNA demethylation through DNA hydroxymethylation, deamination, foundation excision restoration (BER), and additional mechanisms [4, 13C19]. (edrc2013.org)

The covalent bond to FAD in SQR is essential for enzyme activity and the main reason for this is that the bond raises the midpoint redox potential of the flavin by more than 80 mV compared to non-covalently bound flavin. (lu.se)
SQR in E. coli and B. subtilis can be assembled in the membrane without covalently bound FAD but are enzymatically inactive [3, 4, 6]. (lu.se)
The B. subtilis Fp polypeptide was found to lack covalently bound FAD when produced in E. coli although E. coli Fp in the same cell was flavinylated [8]. (lu.se)
It is unexpected that B. subtilis SQR without covalently bound FAD is not assembled in the E. coli membrane provided that all other aspects of assembly, including iron-sulfur cluster biogenesis, are functional in the heterologous system. (lu.se)
Notably, certain B. subtilis mutants with mutated Fp lack covalently bound flavin and do not assemble the SQR polypeptides in the membrane [3]. (lu.se)
The slight difference in electrophoretic mobility of normal Fp and that produced in E. coli could be due to the absence of covalently FAD but could have another explanation because this difference was not observed for some mutant Fp without covalently bound FAD [3]. (lu.se)

They are weak ssDNA binding proteins with no affinity for double-stranded (ds) DNA. (nature.com)
A carefully constructed and calibrated optical tweezers system can position particles with sub-nanometer precision and apply forces over 100 piconewtons (which is enough to unravel a single double-stranded DNA molecule and break most non-covalent bonds). (openwetware.org)
Recently, we have demonstrated high-bandwidth detection of double-stranded (ds) DNA with microsecond time resolution in nanopipettes, using custom-designed electronics. (imperial.ac.uk)
This work describes the development of a new methodology for the detection of specific double-stranded DNA sequences. (nebraska.edu)
These results present SEER as a rapid and sensitive method for the detection of double-stranded DNA sequences. (nebraska.edu)

The purpose of this study was to investigate whether an aberrant DNA methylation of transcriptional and inflammatory factors, including TBX21, GATA3, RORγt, FOXP3, IFN-γ, IL-4, IL-17A and TGF-β , in CD4 + T confers risk to BD. (oncotarget.com)
The full-size grayscale TIFF image of each main figure panel in the manuscript 'CTCF DNA binding domain undergoes dynamic and selective protein-protein interactions ' Our results reveal an interesting phenomenon in which CTCF DBD interacts with insulator proteins and selectively localizes to nuclear positions with lower concentrations of transcriptional activators, providing insights into the insulation function of CTCF. (mendeley.com)
Thus, the existence of repressor-like proteins was demonstrated at the protein level in archaea, raising the question of structural and functional consequences of these proteins on the otherwise eukaryotic-like basal transcriptional machinery in archaea. (ox.ac.uk)
The DNA-binding activity and transcriptional activity of activator protein-1 (AP-1) were measured by electrophoresis mobility shift assay and luciferase assay. (tmu.edu.tw)
In consistent with the results in primary chondrocytes, t-RA down-regulated IL-1-induced AP-1 DNA binding activity and transcriptional activity in a human fibroblast-like (commercially labeled as chondrocyte) cell line. (tmu.edu.tw)

Also, they share a similar protein architecture based on an N-terminal ssDNA binding domain of ~180 amino acids and a C-terminal extension that in the case of RAD52 is required for homologous recombination (HR) through specific protein-protein interactions 6 . (nature.com)
Electrostatic interactions mediate the binding of the Tudor domain with DNA, which is consistent with NMR experiments performed at high salt concentration. (rcsb.org)
Repair of double-strand breaks in DNA, chromatin remodeling during gene transcription (both of these are very important to genome stability and the development and progression of cancer), RNA Polymerase II elongation, site-specific protein-DNA interactions and binding kinetics. (openwetware.org)
Probing protein-DNA interactions by unzipping single DNA molecules with optical tweezers. (openwetware.org)
She launched her thesis work on phage RNA-DNA interactions, but quickly discovered limitations with the tools that were available at the time for experimentation (Resnik 2012). (wepapers.com)
Less appreciated is the fact that SPRi systems provide real-time data, which enables the user to monitor the progress of binding without disturbing molecular interactions. (genengnews.com)
Common among these 10 interactions of organic compounds, their power to detect excess cancer agents is the electrophilic nature of or their metabolites, with DNA and R 1 risk at particular sites. (who.int)

A common feature of these cis-regulatory modules is the presence of multiple binding sites for multiple transcription factors. (sdbonline.org)

Both crystal structures revealed that the N-terminal domain of ~200 amino acids forms a mushroom-shaped undecameric ring with an external groove lined with positive charges, which probably binds the phosphodiester backbone of ssDNA. (nature.com)

Aberrant DNA methylation of GATA binding protein 3 (GATA3), interleukin-4 (IL-4), and transforming growth factor-β (TGF-β) promoters in. (oncotarget.com)
BACKGROUND: Alcohol is known to affect two epigenetic phenomena, DNA methylation and DNA hydroxymethylation, and iron is a cofactor of ten-eleven translocation (TET) enzymes that catalyze the conversion from methylcytosine to hydroxymethylcytosine. (bvsalud.org)
methyltransferasesTET DNA methylcytosine dioxygenasesthe methylated DNA-binding proteins ZBTB38, KDM2B, SETDB1, and additional molecular factors which are involved in diverse epigenetic processes influencing DNA methylation. (edrc2013.org)
While baseline DNA methylation of numerous epigenome focuses on was correlated with cell collection response to antitumor providers, the complex relationships between the overlapping effects of each epigenetic element on methylation of specific focuses on and the importance of such influences in tumor response to individual agents require further investigation. (edrc2013.org)
Our findings suggest complex and interconnected pathways regulating DNA methylation in the epigenome, which may both directly and indirectly impact response to chemotherapy. (edrc2013.org)
and are directly involved in DNA methylation. (edrc2013.org)
Many factors participate in molecular complexes that affect DNA methylation or demethylation, participate in methylation-dependent focusing on of additional molecular factors to genome areas, or regulate binding and/or activities of DNMTs, TETs, and additional epigenetic factors, either directly or via intermediate metabolites. (edrc2013.org)
While many GMDs are involved in methylation or demethylation of 5-mC, MGMT demethylates O6-methylguanine (O6-meG) lesions and removes O6-alkyl adducts, whereas ALKBH2 and ALKBH3 demethylate DNA via removal of 1-methyladenine (N1-meA) and 3-methylcytosine (N3-meC) [37C39]. (edrc2013.org)
A number of epigenetic factors possess complex and intertwined functions influencing DNA methylation. (edrc2013.org)
Specific GMD functions in DNA methylation and demethylation and examples of their relationships are offered in Additional file 1: Table S1 and accompanying text. (edrc2013.org)
HDAC inhibitors (HDACi) impact DNA methylation through a variety of mechanisms. (edrc2013.org)
Vorinostat downregulates transcription of and and changes DNA methylation of and [51C53]. (edrc2013.org)
Blood cell DNA methylation biomarkers in preclinical malignant pleural mesothelioma: The EPIC prospective cohort. (who.int)
Genetic Regulation of DNA Methylation Yields Novel Discoveries in GWAS of Colorectal Cancer. (who.int)

The frequent association of chronic traumatic encephalopathy with other neurodegenerative disorders suggests that repetitive brain trauma and hyperphosphorylated tau protein deposition promote the accumulation of other abnormally aggregated proteins including TAR DNA-binding protein 43, amyloid beta protein and alpha-synuclein. (nih.gov)

Leucine-Responsive Regulatory Protein" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings) . (rush.edu)
This graph shows the total number of publications written about "Leucine-Responsive Regulatory Protein" by people in this website by year, and whether "Leucine-Responsive Regulatory Protein" was a major or minor topic of these publications. (rush.edu)
Below are the most recent publications written about "Leucine-Responsive Regulatory Protein" by people in Profiles. (rush.edu)

The DNA binding mode and key interaction residues were analyzed in detail based on a model structure of the Tudor domain-dsDNA complex, built by HADDOCK docking using the NMR data. (rcsb.org)
The DNA-binding residues are conserved in Tudor domains of the RBBP1 protein family, resulting in conservation of the DNA-binding function in the RBBP1 Tudor domains. (rcsb.org)
The initiating reaction is the nonenzymatic addition of sugars such as glucose to the primary amino groups of proteins, i.e., mainly to lysine residues. (iospress.com)
Sulfur mustard binds to reactive cysteine residues, forming a stable sulfur-hydroxyethylthioethyl [S-HETE] adduct that can be used as a long-term biomarker of sulfur mustard exposure in humans. (cdc.gov)

Chemokine concentrations were measured by ELISA. (tmu.edu.tw)

The main aim of the present systematic review is to evaluate the concentration of 11 frequently reported biomarkers for ALS in peripheral blood and CSF of patients diagnosed with ALS compared with controls. (biomedcentral.com)
We will use the extracted mean and standard deviation (SD) of biomarkers concentrations to calculate the standardized mean difference (SMD) and 95% confidence intervals (CI). (biomedcentral.com)
Exposures in the past have been diagnosed using DNA adducts and urinary metabolites as biomarkers. (cdc.gov)

Modulation of tissue trace metal concentrations in weanling rats fed different levels of zinc and exposed to oral lead and cadmium. (cdc.gov)
Advanced glycation is a major pathway for the posttranslational modification of plasma and tissue proteins. (iospress.com)

The phosphoinositide 3-kinase (PI3K)/protein kinase B (Akt) signaling pathway was recently shown to negatively regulate LPS-induced acute inflammatory responses. (oregonstate.edu)

As a result, a simple and high-throughput method has been developed and validated for the quantitation of sulfur mustard blood protein adducts in low volume blood specimens which should be readily adaptable for quantifying human exposures to other alkylating agents. (cdc.gov)

RNA polymerase is the enzyme that transcribes RNA from DNA and binds DNA at promoter regions. (wepapers.com)
She along with one another graduate student, Bertold Heyden, studied the promoter structure by identifying the RNA polymerase binding site from fd phage. (wepapers.com)

The protein forms a homodimer which localizes to the nucleus and is specifically associated with chromosomes during mitosis. (wikipedia.org)

While bacterial DNA is sometimes used as a blocking agent for standard ChIP, it is not advised for low-input ChIP as it carries through the assay and confounds data analysis . (abcam.com)
The remaining two proteins obtained after HPLC separation were identified as homologues of bacterial repressor-like proteins. (ox.ac.uk)
the result is rapid concentration-dependent bacterial death. (msdmanuals.com)

To the right is a diagram of using optical tweezers to unzip single DNA molecules when there are DNA-binding proteins present in the solution. (openwetware.org)
Usually, the NOE and NMRD in B-DNA is expected to be less ``integral'' than methods can only provide bounds on the residence water molecules buried inside proteins. (lu.se)

Proteins remain tightly bound while DNA is eluted from the matrix. (qiagen.com)
SQR consists of a membrane-peripheral heterodimer domain (often called succinate dehydrogenase) which is tightly bound to a membrane-spanning anchor, which is a cytochrome with one or two heme groups depending on the organism. (lu.se)

However, this does not increase the affinity between cI and OR3, which will be occupied only when the cI concentration is high. (wikidoc.org)

DNA binding reactions and the electrophoresis mobility shift assay were also conducted. (cdc.gov)

Mutation and in vitro DNA binding studies completed on a subset of the CRMs provide evidence for a direct regulatory relationship. (sdbonline.org)
This system, designated sequence-enabled reassembly (SEER), was demonstrated in vitro to produce a DNA-concentration-dependent signal. (nebraska.edu)

Retinoblastoma-binding protein 1 (RBBP1) is a tumor and leukemia suppressor that binds both methylated histone tails and DNA. (rcsb.org)
Our previous studies indicated that RBBP1 possesses a Tudor domain, which cannot bind histone marks. (rcsb.org)
The Hsp90 inhibitor 17-DMAG diminishes the binding of DNMT1 and of the histone methyltransferase EZH2 to Hsp90, attenuates the connection between DNMT1 and EZH2, and mediates the depletion of DNMT1 and EZH2 [50]. (edrc2013.org)
The thermostable histone-like protein Sso7c (Sso for Sulfolobus solfataricus) from the archaeon Sulfolobus solfataricus was purified from the supernatant of acid-soluble cell lysates. (ox.ac.uk)

This LA-dependent increase in Akt phosphorylation was accompanied by inhibition of LPS-induced NF-kappaB DNA binding activity and up-regulation of TNFalpha and monocyte chemoattractant protein 1. (oregonstate.edu)
We showed that t-RA suppressed IL-1-induced release of chemokines, including regulated upon activation, normal T cell expressed and secreted (RANTES), monocyte chemoattractant protein 2 (MCP-2), macrophage inflammatory protein-1alpha (MIP-1α) and MIP-1β. (tmu.edu.tw)

These shared biochemical, protein sequence and functional similarities suggest the existence of an ancestral annealing mechanism involved in HR. (nature.com)
no apparent DNA sequence specificity was detected. (rcsb.org)
As DNA sequencing was not developed at those times, the sequence was established by oligopyrimidine pattern (Nobel, 1996). (wepapers.com)
The original BOB' sequence is changed by the integration to B-O-P'-phage DNA-P-O-B'. The phage DNA is now part of the host's genome. (wikidoc.org)
We previously showed that two inactive fragments of green fluorescent protein, each coupled to engineered zinc finger DNA-binding proteins, were able to reassemble an active reporter complex in the presence of a predefined DNA sequence. (nebraska.edu)
A single base-pair substitution in the DNA binding sequence reduced the signal to nearly background levels. (nebraska.edu)
The proposed method is novel because it works independently of protein sequence databases and without any prior knowledge about modifica- tions. (lu.se)
The matching is com- plicated by the fact that there are protein modifications and the sequence databases store the unmodified sequences. (lu.se)
PTMs from this list in conjunction with a protein sequence and a few precursor masses. (lu.se)
Moreover, speci®c hy- found in narrow minor groove regions in a variety dration patterns seem to play a role in nucleotide sequence recognition by proteins (Otwinowski of oligonucleotide duplexes (PriveÂ et al. (lu.se)

Estrogen, Oral Contraceptives: Estrogens tend to increase serum thyroxine -binding globulin (TBg). (pediatriconcall.com)
Over 90% is bound to serum protein. (msdmanuals.com)

If the membrane-anchor is missing or defective, Fp and Ip subunits accumulate as soluble proteins in the cytoplasm. (lu.se)

The X-ray structure of the casposase bound to DNA representing the product of integration reveals a tetramer with target DNA bound snugly between two dimers in which single-stranded casposon end binding resembles that of spacer 3'-overhangs. (elifesciences.org)

Miniaturization of the assay into microwell formats facilitates automation and increases concentration of the antigen (target transcription factor) during the IP workflow - this avoids the "dilution effect" of low antigen concentrations that favor dissociation of the antibody:antigen complex 4 and decrease the efficiency of ChIP. (abcam.com)

Difference images obtained by digital subtraction of a reference image from a postbinding image allow for visual confirmation of binding: where binding occurs, reflectivity increases and spots become brighter. (genengnews.com)
Avoid use with CYP2D6 substrates where minimal increases in concentration of the CYP2D6 substrate may lead to serious or life-threatening toxicities. (medscape.com)

Label-free systems are widely appreciated in proteomics because there is no need to modify proteins chemically with fluorescent or other tags that might compromise protein function. (genengnews.com)
Low Binding Beads are chemically treated so they bind less solutes liberated from homogenized samples. (opsdiagnostics.com)

Calcium indicators selectively bind to calcium ions. (dojindo.com)

The B subunit of CT binds to the outside of the host cells, allowing the A sub-unit to enter the cell. (kenyon.edu)
The flavin together with the iron-sulfur clusters function to mediate electron transfer from the dicarboxylate binding site on the Fp subunit to the membrane-anchor domain where quinone is reduced to quinol. (lu.se)
Flavinylation of Fp in B. subtilis does not require the Ip subunit or the membrane anchor but depends on folding of the Fp polypeptide into a state that can bind FAD and subsequent mediate covalent binding of the FAD [3, 4]. (lu.se)

The many variables that affect the kinetics of the immunoprecipitation with low concentration antigen can be optimized, including buffer pH, ionic strength and time of incubation 4 . (abcam.com)

Spermidine binds and precipitates DNA and may be used for purification of DNA binding proteins. (botanicure.com)
Further purification of the eluted DNA may be required in some samples because PCR inhibitors may not be completely removed using the described procedure. (cdc.gov)

Untreated silica and zirconium beads have surface chemistries that bind DNA, RNA, and proteins upon disruption of cells. (opsdiagnostics.com)

DNA is probably analogous to the internal hy- pancreatic trypsin inhibitor. (lu.se)

At the molecular level, it was found that replacement of glucose by starch has enhanced the relative expression level of ccpA encoding catabolite control protein A. Therefore, the repression of starch utilization by glucose could be probably relieved. (hindawi.com)

The reason for the observed defective assembly in E. coli is probably not some unidentified mutation in the plasmid DNA because the same plasmid preparation complemented a B. subtilis sdhCAB deletion strain [7]. (lu.se)
DNA was eluted in In this study we report the frequency of 100 µL molecular biology grade water and the CCR5 -delta 32 mutation in the Lebanese stored at -20 °C. DNA concentrations population. (who.int)

Mechanistically, it shares the molecular pathways engaged by other caloric restriction mimetics: It induces protein deacetylation and depends on functional autophagy. (botanicure.com)
These approaches promise to enable researchers to assess, on a large scale, both expression level and functional state of the proteins that carry out most functions in a cell. (lu.se)

Barrier-to-autointegration factor is a protein that in humans is encoded by the BANF1 gene. (wikipedia.org)
The protein encoded by this gene was identified by its ability to protect retroviruses from intramolecular integration and therefore promote intermolecular integration into the host cell genome. (wikipedia.org)
For instance, cI refers to the gene, while cI is the resulting protein encoded by that gene. (wikidoc.org)
In the absence of cI proteins, the cro gene may be transcribed. (wikidoc.org)
In the presence of cI proteins, only the cI gene may be transcribed. (wikidoc.org)
N binds to the two Nut sites, one in the N gene, and one in the cro gene. (wikidoc.org)

Initially these produce N, Cro and a short inactive protein. (wikidoc.org)

The FTA Elute cards contain a chaotropic salt to lyse cells on contact, denature proteins and protect DNA from degradation. (qiagen.com)
We found that 5-ASA at concentrations between 10 and 40 mmol/L affects cell cycle progression by inducing cells to accumulate in the S phase. (nih.gov)
Standard ChIP workflows require a starting sample quantity of around 10 6 to 10 7 cells, below which the assay is hindered by high background binding, poor enrichment efficiencies and loss of enriched library complexity. (abcam.com)
The mechanism of exercise-induced myopathy could be the cell membrane damage by lipid peroxidation and DNA fragmentation in the working muscle cells by free radicals generation. (scielo.org.ar)
They mostly belong to class G or M immunoglobulins and recognize and induce clearance of altered self-structures, including oxidatively damaged components, dying cells and aggregated or misfolded proteins [ 7 - 10 ]. (plos.org)

Substitution of a different custom zinc finger DNA-binding domain produced a signal only on the new cognate target. (nebraska.edu)

PWMs are a useful way to represent binding specificities and provide a statistical framework for searching for novel instances of the motif in genome sequences (Berman, 2002). (sdbonline.org)
Using specific DNA barcodes and whole-genome sequencing, population dynamics were followed, revealing the impact of individual Rap phosphatases and arising mutations on the adaptability of B. subtilis . (nature.com)

The success of proteomics experiments, such as studies of protein function and cell signaling pathways, ultimately de- pends on how well the protein content in samples is identified and annotated. (lu.se)

Once the phage has injected its DNA into its host , the phage DNA may integrate itself into the host cell chromosome. (wikidoc.org)
Both Int and IHF bind to attP and form an intasome , a DNA-protein-complex designed for site-specific recombination of the phage and host DNA. (wikidoc.org)
The lambda phage will remain in the lysogenic state if cI proteins predominate, but will be transformed into the lytic cycle if cro proteins predominate. (wikidoc.org)

T3 in cell cytoplasm and T3 generated from T4 within the cell diffuse into the nucleus and bind to thyroid receptor proteins, which appear to be primarily attached to DNA. (pediatriconcall.com)
Hb, Kr, and Kni are zinc-finger gap proteins that act primarily as repressors in specific embryonic domains. (sdbonline.org)
A LEUCINE and DNA-binding protein that is found primarily in BACTERIA and ARCHAEA. (bvsalud.org)

Additionally, icariin treatment significantly increased the protein levels of Nrf2, a cystine/glutamate transporter (xCT), and glutathione peroxidase 4 (GPX4). (bvsalud.org)

However, since most zinc ions are strongly combined with proteins, the concentration of free zinc ions in a cell is at the millimolar level or lower. (dojindo.com)
A phorbol-12- myristate-13-acetate (16561298) (PMA) dose of 10 nanograms per milliliter, a phenol (108952) dose of 1mg/ml, and a sodium-arsenite (7784465) concentration of 4 millimolar were added to cell cultures. (cdc.gov)

Cell cycle progression, phosphorylation, and DNA binding of cell cycle checkpoint proteins were analyzed. (nih.gov)

The DNA of the prophage that is expressed in that state codes for proteins that look out for signs of stress in the host cell. (wikidoc.org)
At that point, the prophage reactivates, excises itself from the DNA of the host cell and enters its lytic cycle . (wikidoc.org)
Bacteriophage Lambda binds to the target E. coli cell, the tail tip binding to a maltose receptor. (wikidoc.org)
Once the lysogenic pathway is initiated, whether the prophage is excised from the DNA and a lytic cycle begins depends on the amount of stress on the cell: see "Induction" below. (wikidoc.org)
CLS-VF (Cell Lysis/DNA Solubilizing Solution for Vegetation, Cat. (cdc.gov)

By mechanism, DNA annealing proteins are divided into ATPases capable of strand invasion (RecA, RAD51) and single strand annealing proteins (SSAPs) that do not utilize ATP 4 . (nature.com)

Changes in protein concentrations are responsible for the metabolic changes observed in organs and tissues. (pediatriconcall.com)
Changes in the concentration of proteins in various tissues and organs are responsible for metabolic changes. (medscape.com)

DNAbinding proteins combine with DNA through several motifs called zinc fingers, zinc twists, ring fingers, or zinc clusters. (dojindo.com)
A shortage of zinc ions influences DNA transcription, and may have some relationship with the development of cancer. (dojindo.com)

This protein binds to DNA in a non-specific manner and studies in rodents suggest that it also binds to lamina-associated polypeptide 2, a component of the nuclear lamina. (wikipedia.org)

Collectively, our results raise a therapeutic option that intra-articular administration of retinoid derivatives at 10-1000 nanomolar concentrations may be effective to suppress the progression of inflammatory OA. (tmu.edu.tw)

We describe a statistical measure, Mass Distance Fingerprint, for automatic de novo detection of predominant peptide mass distances, i.e., putative protein mod- ifications. (lu.se)

Sample: Recombinant protein. (biomatik.com)

In the present study we aimed to determine the effects of alcohol on DNA hydroxymethylation and further effects of iron on alcohol associated epigenetic changes. (bvsalud.org)

Proteína de unión al ADN y a la LEUCINA que se encuentra principalmente en BACTERIAS y en ARCHAEA. (bvsalud.org)

Anatomy13

Organisms22

Diseases1

Chemicals and Drugs119

Analytical, Diagnostic and Therapeutic Techniques and Equipment28

Phenomena and Processes74

Technology, Industry, Agriculture1

Information Science4

Health Care2

Peptides3

Genomic6

Metabolism3

MRNA5

Replication5

Genes7

Covalently6

Double-stranded5

Transcriptional5

Interactions7

Transcription factors1

Amino acids1

Methylation14

Amyloid beta1

Leucine-Responsive Regulatory Protein3

Residues4

Chemokine1

Biomarkers3

Tissue2

Signaling pathway1

Adducts1

Polymerase2

Mitosis1

Bacterial3

Molecules2

Tightly bound2

Affinity1

Electrophoresis mobility shift assay1

Vitro2

Histone4

Monocyte2

Sequence10

Serum2

Soluble1

Single-stranded1

Favor1

Increases2

Chemically2

Selectively1

Subunit3

Kinetics1

Purification2

Disruption1

Pancreatic1

Repression1

Mutation2

Functional2

Gene6

Inactive1

Cells5

Cognate1

Genome2

Pathways1

Phage3

Primarily3

Significantly increased1

Millimolar2

Phosphorylation1

Cell5

Mechanism1

Metabolic2

Zinc2

Polypeptide1

Progression1

Putative1

Recombinant1

Hydroxymethylation1

ARCHAEA1