• For this reason, in the recent five years hydroxyapatite particles and whiskers have been added as novel bioactive and biocompatible reinforcing filler in dental restorations. (hindawi.com)
  • Please note that the screws should not be placed near the edge of the cement as this may cause a fracture of the bone-void filler. (aofoundation.org)
  • Two screws were placed through the fiber-enhanced calcium phosphate. (aofoundation.org)
  • In fact, it was shown that the incorporation of hydroxyapatite with whiskers morphology can provide larger load transfer and favor toughening mechanisms, thus, increasing flexural modulus and fracture toughness of resins in comparison with conventional silica based fillers [ 6 - 11 ]. (hindawi.com)
  • One of the major properties of most types of CaPO 4 is their osteoconductivity, an ability to favor bone healing and to bind firmly to bone tissues. (encyclopedia.pub)
  • The recognition and importance of immune cells during bone regeneration, including around bone biomaterials, has led to the development of an entire field termed "osteoimmunology," which focuses on the connection and interplay between the skeletal system and immune cells. (bvsalud.org)
  • Most studies have focused on the "osteogenic" capacity of various types of bone biomaterials, and much less focus has been placed on immune cells despite being the first cell type in contact with implantable devices. (bvsalud.org)
  • These findings highlight and recognize the importance of the immune system and osteoimmunology, leading to a shift in the traditional models used to understand and evaluate biomaterials for bone regeneration. (bvsalud.org)
  • If compared with other types of bioceramics (such as alumina, zirconia, calcium silicates, calcium sulfate, etc.), the main feature and superiority of CaPO 4 is based on their chemical similarity to the composition of calcified tissues of mammals (bones, teeth, and deer antlers) and the need for versatile and risk-free bone substitute biomaterials immediately available without the constraint of bone grafts. (encyclopedia.pub)
  • In large bone lesions, such as severe bone fractures, bone cancer or other diseases, bone grafts substituting the lost bone might be necessary. (bvsalud.org)
  • Such grafts can be of biological origin or be composed of a synthetic bone substitute. (bvsalud.org)
  • A strong interest was raised in studying ceramics as potential bone grafts due to their biomechanical properties. (encyclopedia.pub)
  • Current biomedical applications of CaPO 4 -based bioceramics include artificial bone grafts, bone augmentations, maxillofacial reconstruction, spinal fusion, and periodontal disease repairs, as well as bone fillers after tumor surgery. (encyclopedia.pub)
  • Norian drillable is a calcium-phosphate-based bone-void filler, based on the same ceramic phase as Norian SRS. (aofoundation.org)
  • The ceramic component is slowly remodeled over a period of years, at a rate depending on the metabolic activity of the host bone. (aofoundation.org)
  • In addition, hydroxyapatite whiskers (wHA) have been considered the best option as reinforcing filler in comparison with other whiskers based on carbon, ceramic, glass, metal, and polymer due to the absence of cytotoxicity effects [ 12 , 13 ]. (hindawi.com)
  • Data obtained show better interfacial interaction with filler/matrix until 20 wt% of hydroxyapatite whiskers partially replaced silica particles filler. (hindawi.com)
  • Synchrotron nanoCT imaging has great potential to contribute to further the understanding of integration of implants into bone tissue by imaging the spatial interaction between bone tissue and implant, and by accessing the interface between implant material and bone tissue. (bvsalud.org)
  • Nowadays, in order to avoid limits affecting long-term durability of resin composites, dental materials companies are focusing their attention on the improvement of the mechanical and biological properties of filler. (hindawi.com)
  • When fully cured, the composition formed closely approximates the mineral phase of bone. (aofoundation.org)
  • Thus, working on filler packing, optimization of filler content, and development of a new innovative fillers is needed. (hindawi.com)
  • With this aim, a methodology for evaluating the image quality is presented for in-line phase contrast nanoCT images of bone scaffold samples. (bvsalud.org)
  • First, the various immune cell types involved in bone biomaterial integration are discussed, including the prominent role of osteal macrophages (OsteoMacs) during bone regeneration. (bvsalud.org)