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PerilymphEndolymphLabyrinthine FluidsScala TympaniRound Window, EarCochleaEndolymphatic HydropsEar, InnerMeniere DiseaseScala VestibuliCochlear Microphonic PotentialsStria VascularisOtolithic MembraneTympanic MembraneLabyrinth DiseasesSaccule and UtricleSemicircular CanalsEndolymphatic SacEndolymphatic DuctStapesGuinea PigsStapes SurgeryFistulaBody CompositionBatrachoidiformesTympanic Membrane PerforationAmikacinAudiometry, Evoked ResponseKanamycin

Membranous labyrinthExtracellular fluidCerebrospinal fluidSemicircularVestibuleResemblesFluidCochlearIonicTympaniElectrolyteVestibularFluidsConcentrationPerilymphaticBarrierSpiralFlowStructure

Membranous labyrinth4

• The membranous labyrinth contains endolymph, and is surrounded by perilymph. (wikipedia.org)
• The membranous labyrinth is surrounded by perilymph and suspended by fine connective tissue strands from the bony labyrinth. (medscape.com)
• It consists of a bony shell (the bony labyrinth) within which is found the membranous labyrinth-a series of cavities forming a closed system filled with endolymph, a potassium-rich liquid. (cloudaccess.net)
• The membranous labyrinth is separated from the bony labyrinth by the perilymph, a sodium-rich liquid. (cloudaccess.net)

Extracellular fluid3

• Perilymph is an extracellular fluid located within the inner ear. (wikipedia.org)
• perilymph resembles extracellular fluid in composition (sodium salts are the predominant positive electrolyte) and, via the cochlear aqueduct (sometimes referred to as the "perilymphatic duct"), is in continuity with cerebrospinal fluid. (wikipedia.org)
• [ 2 ] In contrast, the composition of perilymph resembles that of extracellular fluid and is high in Na + and low in K + . These differences in electrolyte concentrations remain fairly constant throughout the cochlea, although slight differences are noted in the electrolyte composition of scala vestibuli and scala tympani and between the basal and apical portions of scala media. (medscape.com)

Cerebrospinal fluid3

• The ionic composition of perilymph is comparable to that of plasma and cerebrospinal fluid. (wikipedia.org)
• The perilymph in the bony labyrinth serves as connection to the cerebrospinal fluid of the subarachnoid space via the perilymphatic duct. (wikipedia.org)
• This fluid is similar in composition to cerebrospinal fluid. (justfactsllc.com)

Semicircular1

• Motion sickness can be caused when the endolymph of the semicircular canals is compromised. (weilab.com)

Vestibule1

• The so-called bony labyrinth includes the scalae vestibule and tympani and contains perilymph. (justfactsllc.com)

Resembles1

• endolymph resembles intracellular fluid in composition (potassium is the main cation). (wikipedia.org)

Fluid3

• The bony labyrinth is filled with a fluid called perilymph and encloses the membraneous labyrinth. (kenyon.edu)
• It is filled with a seperate fluid that does not mix with the perilymph called endolymph. (kenyon.edu)
• The cochlea and the vestibular system are filled with fluid, called endolymph, and they are also soaked in the fluid called perilymph. (weilab.com)

Cochlear3

• Apart from the importance in the electric cochlear potential, the perilymph also contains a large number of proteins, e.g. extracellular enzymes and immunoglobulins. (wikipedia.org)
• An image depicting the divisions and electrolyte compositions of the cochlear compartments can be seen below. (medscape.com)
• The divisions and electrolyte compositions of the cochlear compartments. (medscape.com)

Ionic1

• Perilymph and endolymph have unique ionic compositions suited to their functions in regulating electrochemical impulses of hair cells necessary for hearing. (wikipedia.org)

Tympani1

• The scalae tympani and scala vestibuli communicate with each other and are filled with perilymph . (medscape.com)

Electrolyte2

• The difference between the electrolyte composition of the perilymphatic and endolymphatic spaces creates an electrochemical environment that makes sensorineural transduction possible. (medscape.com)
• In the spiral ligament and stria vascularis reside the enzyme systems and cellular organelles necessary for the maintenance of the differences in electrolyte content between the perilymph and endolymph. (medscape.com)

Vestibular1

• The proteome of perilymph in patients with vestibular schwannoma. (wikipedia.org)

Fluids1

• A characteristic of perilymph is that its concentration of sodium is high (about 150 milliequivalents per litre) and its concentration of potassium is low (about 5 milliequivalents per litre), similar to other extracellular fluids. (kenyon.edu)

Concentration4

• The major cation in perilymph is sodium, with the values of sodium and potassium concentration in the perilymph being 138 mM and 6.9 mM, respectively. (wikipedia.org)
• The electric potential of endolymph is ~80-90 mV more positive than perilymph due to a higher concentration of potassium cations (K+) in endolymph and higher sodium (Na+) in perilymph. (wikipedia.org)
• Pumping of K + into the endolymph occurs against a concentration gradient and thus requires energy expenditure. (medscape.com)
• Conversely endolymph has a low concentration of sodium (about 15 milliequivalents per litre) and a high concentration of potassium (about 140 milliequivalents per litre). (kenyon.edu)

Perilymphatic1

• The scala media is isolated from the perilymphatic space and contains endolymph. (medscape.com)

Barrier3

• The basic principles of this local control are illustrated in the images below and are outlined as follows: First, an anatomic barrier exists between perilymph and endolymph, and it consists of Reissner membrane, the stria vascularis, and the reticular lamina formed by tight junctions between the apices of hair cells and the adjacent supporting cells (see the image above). (medscape.com)
• Second, despite this anatomic barrier, electrolytes slowly leak down concentrating gradients (eg, K + flow from endolymph to perilymph). (medscape.com)
• In addition to nutrients, small concentrations of immunoglobulins present in blood serum are also found in the perylimph and endolymph, filtered through by the blood-labyrinth barrier (15). (kenyon.edu)

Spiral2

• Third, electrolytes (eg, K + ) that flow into perilymph are returned to the endolymph via the spiral ligament and stria vascularis (see the second image below). (medscape.com)
• They serve to transport K + through the spiral ligament and stria vascularis, and they secrete it into the endolymph. (medscape.com)

Flow2

• It has also been suggested that perilymph and endolymph participate in a unidirectional flow that is interrupted in Ménière's disease. (wikipedia.org)
• However, it now appears that substantial longitudinal flow of perilymph or endolymph does not occur. (medscape.com)

Structure1

• The corneo-scleral layer supports the structure of the eye with its tough fibroelastic composition. (medcell.org)