Complications antiviral agents. Medical search. Frequent questions

Conference highlights include direct-acting antiviral therapy for difficult-to-treat people with hepatitis C, novel hepatitis B agents, complications of viral hepatitis, and NAFLD/NASH. (hivandhepatitis.com)
Study patients treated in the interferon era will likely have different comorbid disease burden than those treated in the direct-acting antiviral era, limiting the generalizability off the findings. (va.gov)

The conclusion of the panel was that it would be appropriate, and possibly essential, to develop antiviral drugs for PV infection, as an additional tool to address the problems that might arise in the "postpolio" era ( 6 ). (cdc.gov)
NO donor or NOS2 overexpression provides protection from virus infection in CF, suggesting that NO is sufficient for antiviral host defense in the human airway and is one strategy for antiviral therapy in CF children. (nih.gov)
The disease is considered benign and self-limited but complications may arise, particularly when the illness results from infection with EV 71. (canada.ca)
It should be noted that infection with EV 71 may result in complications without producing clinically-evident HFMD. (canada.ca)
No specific antiviral agent is available for therapy or prophylaxis of EV 71 infection. (canada.ca)
In February 2016, Cafferkey was readmitted to the Royal Free Hospital due to complications from her infection, but later that month declared not to be infectious and discharged. (wikipedia.org)
In a statement the Royal Free said she had been transferred to the hospital "due to a late complication from her previous infection by the Ebola virus" and that she was being treated by the hospital's infectious diseases team. (wikipedia.org)
Antiviral chemoprophylaxis is recommended for the prevention of influenza virus infection as an adjunct to vaccination in certain individuals, especially exposed children who are at high risk for To cite: AAP Committee on Infectious Diseases. (cdc.gov)
This may include oxygen for hypoxaemia and ventilatory support, along with optimal management of complications, e.g. super-imposed bacterial infection, and any underlying co-morbidities, e.g. chronic obstructive pulmonary disease, congestive heart failure. (ersjournals.com)
A third category of CMV infection can occur as a complication of AIDS ( acquired immunodeficiency syndrome ). (encyclopedia.com)
The increase in cirrhosis complications in women with active HCV infection is similar to those in men. (va.gov)
HBV infection is considered the most important causative agent of HCC, with approximately 240 million people infected worldwide, especially in the Asia-Pacific and African regions [ 6 , 7 , 8 ]. (biomedcentral.com)
Neurologic complications due to acute Epstein-Barr virus infection include acute encephalitis, cerebellar ataxia, cranial nerve palsies, and Guillain-Barré syndrome. (medlink.com)
Neurologic symptoms can be seen with infectious and postinfectious complications of Epstein-Barr virus infection. (medlink.com)
02 ). Meningitis and encephalitis are the most common complications of acute Epstein-Barr virus infection, with encephalitis being less frequent than meningitis. (medlink.com)
Neurosarcoidosis and cryoglobulinemia are rare but well-recognized complications of HCV infection, even in treatment-naïve patients. (scielo.pt)
A bacterial infection of the skin where the rash happens is another complication. (shinglestalk.com)

A panel convoked by the National Research Council concluded that the use of antiviral drugs may be essential in the polio eradication strategy. (cdc.gov)
Therefore, research initiatives leading to the successful development of anti-PV drugs will have to rely on the current knowledge of existing picornavirus antiviral agents. (cdc.gov)
Antipicornavirus compounds that reached clinical trials are scarce, and despite the fact that some of these drugs have demonstrated activity against certain picornavirus-associated conditions in humans, no specific antipicornavirus agent has yet been approved by the US Food and Drug Administration (FDA) ( 8 ). (cdc.gov)
Although currently available antiviral drugs can reduce the symptoms of influenza and limit virus transmission, the possibility of selecting resistant strains still exists, meaning influenza treatment continues to be a challenge. (pharmacytimes.com)
2016-2017 Influenza Antiviral Recommendations Don't miss the update from CDC with this year's recommendations for antiviral drugs in the treatment of influenza. (medscape.com)
In Canada, two available measures can reduce the impact of influenza: immunoprophylaxis with inactivated (killed-virus) vaccine and chemoprophylaxis or therapy with influenza-specific antiviral drugs. (canada.ca)
If you suspect it is Zoster, get to MD asap or go to Healthtap, a Virtual MD pratice I use (see bottom of this blog post to learn more about how to make a virtual appointment with an MD for an antiviral Rx) & ask the MD to prescribe the drugs noted on this blog post. (drcremers.com)
Diabetic patients are more susceptible to severity and incidence of COVID-19, antidiabetic agents may interact with antiviral drugs and other therapeutic agents used in management of COVID-19, thus, caution should be taken in consideration upon selection of drug treatment to avoid undesirable potential adverse events or lack of therapeutic efficacy. (actascientific.com)
Unlike traditional antiviral drugs, which often target viral enzymes or proteins, peptide-based agents utilize short chains of amino acids to disrupt viral mechanisms. (researchpeptides.net)
4. Resistance development: While resistance to traditional antiviral drugs can emerge over time, peptide-based agents have shown a lower propensity for resistance development. (researchpeptides.net)

2000 IU/mL who underwent hepatectomy at Zhongnan Hospital of Wuhan University between March 2013 and December 2017, of whom 157 patients received antiviral therapy (antiviral group) and 139 patients did not receive antiviral therapy (non-antiviral group), propensity score matching was used for survival analysis of patients in both groups, and subgroup analysis of major risk factors was performed. (biomedcentral.com)

Her doctors stated that she had been critically ill due to neurological complications from meningitis, and that she had been treated using a highly experimental anti-viral agent. (wikipedia.org)

Once cirrhosis develops, treatment is aimed at the management of complications as they arise. (medscape.com)
Treatment is supportive and focuses on management of complications. (canada.ca)

The ACIP also publishes recommendations on the use of antiviral agents for prevention and treatment of influenza . (medscape.com)
Antiviral agents available for influenza treatment and/or prevention include neuraminidase inhibitors (oseltamivir, peramivir, zanamivir) and the cap-dependent endonuclease inhibitor (baloxavir marboxil). (medscape.com)
This statement updates the recommendations of the American Academy abstract of Pediatrics for the routine use of influenza vaccine and antiviral medications in the prevention and treatment of influenza in children during the 2023-2024 influenza season. (cdc.gov)
Antiviral treatment of influenza is recommended for children with the organizations or government agencies that they represent. (cdc.gov)
Antiviral treatment should be initiated as soon as possible. (cdc.gov)
Several published clinical trials provide evidence that Doxil is an active agent in multiple myeloma and it is used in treatment combinations for multiple myeloma in general practice. (drugpatentwatch.com)
However, the benefits of HCV treatment must be extended to all patients in order to stem the rising tide of HCV complications. (va.gov)
For example, although investigators had information on antiviral treatment, they opted not to include this variable in their analysis given similar treatment rates in the two study groups - and the low efficacy of previous interferon-based treatment used during the study time frame. (va.gov)
Currently the rate of fungal infections across the globe is increasing and given increasing rates of resistance to a limited number of treatment options, new anti-fungal agents are desperately needed. (mtsu.edu)
Antiviral medications with activity against influenza viruses are useful adjuncts in the prevention of influenza, and effective when used early in the course of illness for treatment. (web.app)
Apart from vaccination and antiviral treatment the public health management includes personal protective measures. (web.app)
Receipt of curative antiviral treatment was associated with a reduction in the risk of cirrhosis, HCC, and overall mortality, irrespective of age. (va.gov)
Although we are living in a new era of HCV treatment, there is still little data concerning the treatment of extrahepatic complications of the disease with direct antiviral agents, especially rare ones such as neurosarcoidosis. (scielo.pt)
Antiviral treatment during late pregnancy effectively reduced MTCT. (e-cmh.org)
19 A recent systematic review by Matheson et al 20 confirmed the beneficial role of the neuraminidase inhibitors (Zanamivir and Oseltamivir) for treatment and probable prevention of influenza complications in children. (health.gov.au)
Starting antiviral medication treatment within 3 days of the rash first appearing can lower your risk of developing complications, like long-term pain. (shinglestalk.com)
The treatment approach to chickenpox depends on a number of factors, including the risk of complications to the person infected. (regentstreetclinic.co.uk)
however, antiviral treatment has a limited effect and must be started as soon as possible after the rash first develops. (regentstreetclinic.co.uk)
Treatment with HAART is not without complications. (i-sis.org.uk)
Patient's age, comorbidities, and presentation after 48 hours of symptom onset were not associated with antiviral treatment. (authorea.com)
Our findings revealed the physicians' rationale for initiating antiviral treatment and the discrepancy with guideline indications of antivirals, which is patient's age and comorbidities. (authorea.com)
Peptide-based agents have emerged as a promising approach for the treatment of viral infections. (researchpeptides.net)

Mechanism of Action of Antifungal Peptoids Due to the rise of drug resistant strains of fungal pathogens such as Cryptococcus neoformans and Candida albicans, there has been a need to identify new antifungal agents. (mtsu.edu)
RMG8-8 and RMG9-11, two peptoids recently discovered in the Bicker Lab, have proven to be effective antifungal agents against C. neoformans and C. albicans, respectively. (mtsu.edu)

Complications include encephalitis, aseptic meningitis, acute flaccid paralysis, pulmonary edema or hemorrhage and myocarditis. (canada.ca)
Antibiotics are of absolutely no use for influenza and are used only for bacterial complications after the acute phase is over. (fightflu.com)
About 42.3% of COVID-19 mortalities were diabetic patients, death rates were significantly higher in hospitalized type 2 diabetic patients than non-diabetic ones and were more susceptible to acute respiratory distress syndrome and other life threatening complications. (actascientific.com)

The most common serious complications of influenza include exacerbation of underlying chronic pulmonary and cardiopulmonary diseases, such as worsening of chronic obstructive pulmonary disease, asthma, and congestive heart failure, as well the development of pneumonia. (antiinfectivemeds.com)
Patients at risk of severe neurologic or other systemic complications (eg, pneumonia) include adults, neonates, and patients who are immunocompromised or have certain underlying medical conditions. (msdmanuals.com)

Reinfection with HPIV can occur throughout life, with elderly and immunocompromised persons being at a greater risk for serious complications of infections. (medscape.com)
Influenza is usually considered a mild winter-time illness but can be associated with a range of serious complications. (health.gov.au)
Certain groups of people, however, are at greater risk of serious complications from chickenpox. (regentstreetclinic.co.uk)

antibiotics are used only if bacterial complications (eg, otitis and sinusitis) develop. (medscape.com)
Early 'point of care' testing, use of influenza-specific antiviral agents, and extension of current vaccination schedules to include all children aged six to 23 months could considerably reduce over-investigation, unnecessary use of antibiotics and the health care impact of influenza. (health.gov.au)
Point of care testing and influenza-specific antiviral agents are rarely used and thus many children are managed with unnecessary antibiotics and invasive procedures such as lumbar puncture. (health.gov.au)

Physicians with more years of experience were significantly more likely to prescribe antivirals for patients with low risk of complications. (authorea.com)

Young children and young adults have a predilection for symptomatic infections, with severity ranging from mild to fulminant life-threatening complications. (medlink.com)

Given the accelerated progression to advanced liver disease, elderly patients with chronic hepatitis C constitute a high-risk group that may need to be prioritized in the era of new antiviral treatments. (va.gov)
The most common treatments for shingles are antiviral medications, pain relievers, and creams or patches. (amaravatigrill.com)
Peptide-based anti-viral agents offer several advantages over conventional treatments. (researchpeptides.net)

Interestingly, certain outbreaks of HFMD due to EV 71 have been associated with severe neurological complications and significant mortality while others have been associated with relatively fewer complications and little mortality. (canada.ca)
Influenza vaccination is the primary method for preventing influenza and its severe complications. (cdc.gov)
[ 2 ] Early antiviral therapy must be considered among hospitalized children diagnosed with or suspected to have influenza, especially if they have risk factors such as asthma, cardiac problems, or other conditions, to prevent severe complications and prolonged hospitalization. (medscape.com)
In the IFN-free regimen era we are currently living in, treating HCV extrahepatic manifestations with direct antiviral agents (DAAs) is recommended [3], leaving other immunosuppressive therapies, such as corticosteroids or rituximab, usually used in combination with DAAs for very severe manifestations. (scielo.pt)
Hepatitis B e antigen seroconversion can occur in mothers who undergo persistent antiviral therapy or severe hepatitis after delivery. (e-cmh.org)

In Australia influenza vaccination is recommended only for children at high-risk of complications. (health.gov.au)
Programs should focus on those at high risk of influenza-related complications, those capable of transmitting influenza to individuals at high risk of complications, and those who provide essential community services. (canada.ca)

Teravir 300mg Tablet is an antiviral medication. (careexim.in)

Influenza viruses also can cause pandemics, during which rates of illness and death from influenza-related complications can increase worldwide. (cdc.gov)

Antiviral therapy has been shown to benefit long-term survival after curative hepatectomy in patients with hepatitis B virus (HBV)-associated hepatocellular carcinoma (HCC) with high levels of HBV-DNA, but the impact of antiviral therapy on patient recurrence in patients with low levels of HBV-DNA remains less clear. (biomedcentral.com)
Overall, there are relatively few data regarding the effectiveness of antiviral therapy after curative hepatectomy for HCC, especially in patients with HBV-associated HCC with low levels of HBV-DNA, and it is still not well known whether antiviral therapy is effective in preventing recurrence of metastasis after curative hepatectomy in patients. (biomedcentral.com)

Neuraminidase inhibitors (NIs) were used as an antiviral agent because neuraminidase can facilitate the release of viral particles by severing the sialic acid groups hemagglutinin-a surface protein influenza uses-is bound to. (pharmacytimes.com)
Neuraminidase inhibitors are again recommended as the first-line antiviral agents for the prevention of influenza rather than amantadine. (canada.ca)

To do this ABIVAX leverages three technology platforms for drug discovery: antiviral, immune enhancing and polyclonal antibodies. (evotec.com)
4. Modulation of host immune response: Some peptides can enhance the host immune response against viral infections by stimulating the production of antiviral cytokines or activating immune cells. (researchpeptides.net)
Example: Synthetic peptides known as Toll-like receptor agonists can activate immune cells and promote antiviral responses. (researchpeptides.net)

Spain is making dramatic progress towards eliminating hepatitis C among people living with HIV because of widespread use of direct-acting antivirals, Juan Berenguer of Hospital Gregorio Marañón in Madrid reported last week at the 16th European AIDS Conference (EACS 2017) in Milan. (hivandhepatitis.com)
There have been numerous efforts to reduce mother-to-child transmission (MTCT) of hepatitis B virus (HBV) with antiviral agents during pregnancy. (e-cmh.org)
Administrating antiviral agents during late pregnancy can effectively reduce maternal hepatitis B virus-DNA levels and successfully prevent perinatal transmissions. (e-cmh.org)
Postpartum biochemical flare is likely to occur in mothers who had previously been treated for chronic hepatitis B and discontinued antivirals for pregnancy. (e-cmh.org)

Gastrointestinal manifestations, such as vomiting, abdominal pain, and diarrhea, and other complications such as myositis, croup (tracheobronchitis), and otitis media also occur more frequently in children. (antiinfectivemeds.com)

Moreover, it is estimated that at least one-third of patients with this condition will progress to advanced fibrosis and cirrhosis - a subset at high risk for subsequent complications, including hepatocellular cancer (HCC). (va.gov)

Concomitantly, there have been efforts to evaluate the efficacy of immunomodulatory, antiviral, and anti-seizure therapies that could ameliorate the devastating effects of this disease. (aku.edu)
This study was performed to evaluate the efficacy of antiviral agents in preventing MTCT of HBV and maternal long-term outcomes. (e-cmh.org)
However, ongoing research efforts are focused on addressing these limitations and optimizing the efficacy and safety profiles of peptide-based anti-viral agents. (researchpeptides.net)
1. Effectiveness: Peptide-based agents have demonstrated efficacy against a wide range of viruses, including drug-resistant strains. (researchpeptides.net)

These agents are inhibitors of DNA polymerase in herpes simplex virus (HSV)-1 and HSV-2 strains, inhibiting viral replication. (medscape.com)
Postherpetic neuralgia (PHN) is the most common complication of herpes zoster. (drcremers.com)

Diabetes is considered as one of the main contributing factors of high morbidity and mortality rates globally, where, uncontrolled diabetes is associated with macro- and micro-vascular complications affecting patient's health wellbeing and survival. (actascientific.com)

The most common complication of shingles is postherpetic neuralgia, which affects around 5-20% of people with shingles. (amaravatigrill.com)
2. Start Gabapentin or the other meds discussed below to prevent Postherpetic Neuralgia (PNH) which is a dreaded complication of Zoster as it can cause long term pain which can sometimes be worse than the original Zoster. (drcremers.com)

These agents are used to treat secondary yeast infections. (medscape.com)
By targeting specific steps in the viral life cycle, these agents offer a unique approach to managing viral infections. (researchpeptides.net)

399,000 people die annually from complications of liver cirrhosis, including hepatocellular carcinoma. (bvsalud.org)

Models did not control for factors that might preclude prescription for older antivirals (e.g., mental illness diagnoses and interferon). (va.gov)

These findings suggest that antiviral therapy may have a positive impact on reducing recurrence in patients with HBV-associated hepatocellular carcinoma. (biomedcentral.com)

Most deaths associated with influenza in industrialized countries are due to complications of underlying diseases in people with well defined risks, including age over 65 years, chronic cardiovascular, pulmonary, metabolic or renal disease, and immunosuppression. (who.int)

3. Broad-spectrum activity: Unlike many conventional antivirals that are specific to a particular virus or family of viruses, peptide-based agents can be designed to have broad-spectrum activity. (researchpeptides.net)

The incidence and prevalence of HCV complications was higher in men than in women. (va.gov)

However, some studies have also shown no difference in prognosis of HBV-associated HCC patients with antiviral drug therapy [ 20 , 21 ]. (biomedcentral.com)
To this end, we conducted a retrospective study to assess the effect of antiviral drug therapy on recurrence and survival after hepatectomy in patients with HBV-associated HCC with low levels of HBV-DNA. (biomedcentral.com)

Multivariable analysis revealed that a positive RIDT had the largest effect on antiviral prescription, followed by physician status, high regional influenza activity, and patients' presentation within 12 hours of symptom onset. (authorea.com)

Most antiviral agents are CYP450 inhibitors or inducers or CYP450 substrates, thus, drug interactions might occur with CYP450 substrates as thiazolidinediones, sulfonylureas, and short-acting secretagogues used in the management of diabetes. (actascientific.com)

A panel was convened by the National Research Council to evaluate the potential for an antiviral drug as one of the tools to minimize poliomyelitis risk after OPV cessation. (cdc.gov)
2 years, and persons of any age who have medical conditions that place them at increased risk for complications from influenza ( 2,5--7 ). (cdc.gov)
risk of complications of influenza, regardless of duration of illness. (cdc.gov)
In 1975, mAbs were first developed by Kohler and Milstein with palivizumab being the first antiviral mAb approved for the prophylaxis of respiratory syncytial virus in high-risk infants by the United States Food and Drug Administration (FDA) [ 5 ]. (journalmc.org)
Association of physician experience with higher prescription rate of anti-influenza agents in low-risk patients. (authorea.com)

130 IU/L, and the presence of satellite nodules, and subgroup analysis showed that compared to HBeAg-positive patients, antiviral therapy could significantly prolonged the recurrence-free survival of HBeAg-negative patients. (biomedcentral.com)
Antiviral therapy reduces early tumor recurrence after hepatectomy in patients with low levels of HBV-DNA. (biomedcentral.com)
The mean HBV DNA titer before antiviral therapy was 8.67 (6.60-9.49) log copies/mL, and the median age at delivery was 32 years (range, 22-40). (e-cmh.org)
Antiviral therapy suppresses the replication of the HIV virus in the body. (i-sis.org.uk)
A combination of several antiretroviral agents, termed Highly Active Anti-Retroviral Therapy (HAART), has been highly effective in reducing the number of HIV particles in the blood stream (as measured by a blood test called the viral load). (i-sis.org.uk)
The coronavirus disease 2019 (COVID-19) pandemic emerged as a world crisis in 2019 and started a global search for optimal therapeutic regimen including vaccines, antiviral agents, and recently monoclonal antibody therapy. (journalmc.org)

The HBV-infected pregnant women treated with antiviral agents to prevent MTCT were retrospectively reviewed. (e-cmh.org)

In October 2015, Cafferkey was diagnosed with late complications caused by the Ebola virus hitherto considered unusual, and readmitted to the Royal Free Hospital. (wikipedia.org)

p = 0.001, and the overall survival and recurrence-free survival were significantly better in the antiviral group than in the non-antiviral group. (biomedcentral.com)

These mechanisms highlight the diverse ways in which peptide-based agents can disrupt viral replication and reduce viral load within infected individuals. (researchpeptides.net)

Antiviral agents do not confer immunity but could be used prophylactically as well as therapeutically. (cdc.gov)

It is a first-in-class oral small antiviral molecule which blocks HIV replication through a unique mechanism of action and, separately, also has a strong anti-inflammatory effect. (evotec.com)
These agents are designed to target specific components or processes involved in viral replication and entry into host cells. (researchpeptides.net)

Liver manifestations vary according to the degree of fibrosis, portal hypertension complications, and the severity of liver failure. (scielo.pt)
3 There is a wide range of symptom severity from minor respiratory illness to life-threatening multi-system complications and death. (health.gov.au)

Anatomy9

Organisms33

Diseases43

Chemicals and Drugs77

Analytical, Diagnostic and Therapeutic Techniques and Equipment59

Phenomena and Processes34

Disciplines and Occupations1

Technology, Industry, Agriculture1

Information Science6

Named Groups1

Health Care18

Geographicals1

Direct-acting an2

Infection17

Drugs10

Receive antiviral1

Neurological complications from meningitis1

Management of complications2

Treatment22

Antifungal Agents2

Acute3

Pneumonia2

Serious complications3

Antibiotics3

Prescribe1

Life-threatening c1

Treatments3

Severe5

High-risk of complications2

Medication1

Influenza-related1

Curative2

Neuraminidase2

Immune3

Hepatitis4

Croup1

Hepatocellular Cancer1

Efficacy4

Herpes2

Patient's1

Postherpetic2

Infections2

Cirrhosis1

Interferon1

FINDINGS1

Pulmonary1

Viruses1

Incidence1

Drug therapy2

Onset1

Inhibitors1

Risk5

Therapy6

Retrospectively reviewed1

Cafferkey1

Significantly1

Viral load1

Immunity1

Replication2

Severity2