OBJECTIVES: We sought to determine vaccine antibody titres and the prevalence of hepatitis B surface antigen (HBsAg) in both HIV-positive and HIV-negative infants born to HIV-positive mothers in Botswana. (bvsalud.org)
The haplotype can be written in an extended form covering the major histocompatibility loci as follows: HLA Cw*0702 : B*0702 : DRB1*1501 : DQA1*0102 : DQB1*0602 The older literature may describe this haplotype in two different ways. (wikipedia.org)
HLA 1991: proceedings of the eleventh International Histocompatibility Workshop and Conference, held in Yokohama, Japan, 6-13 November 1991. (wikipedia.org)
Our identification of the first non-human primate-specific minor histocompatibility antigen now published at Frontiers in Immunology. (wisc.edu)
This phase I trial assessed the safety, efficacy, and immunologic responses to minor histocompatibility antigens following nonmyeloablative allogeneic hematopoietic cell transplantation as treatment for metastatic renal cell carcinoma. (aacrjournals.org)
Patients were monitored for donor engraftment of myeloid and lymphoid cells, for clinical response by serial imaging, and for immunologic response by in vitro isolation of donor-derived CD8 + CTLs recognizing recipient minor histocompatibility (H) antigens. (aacrjournals.org)
Hematopoietic2
Overexpression of CD30 antigen in hematopoietic malignancies make the antigen clinically useful as a biological tumor marker. (lookformedical.com)
Eight patients received conditioning with fludarabine and low-dose total body irradiation followed by hematopoietic cell transplantation from an HLA-matched sibling donor. (aacrjournals.org)
Tumor2
Clones from three patients with a partial response or stable disease recognized antigens expressed on renal cell carcinoma tumor cells. (aacrjournals.org)
CD8 + CTL-recognizing minor H antigens on tumor cells can be isolated posttransplant and could contribute to the graft- versus -tumor effect. (aacrjournals.org)
Human1
Overall primary concerns are: extrapolating human clinical studies, seeding durable effective T cell resident memory (Trm), population human leucocyte antigen (HLA) coverage, and the potential for T cell-mediated immune escape. (mdpi.com)
Immune1
Molecular docking, molecular dynamic simulation, and immune simulation were performed to ensure the binding between HLA and TLR4. (springeropen.com)
Minor1
CD8 + CTL clones recognizing minor H antigens were isolated from five patients studied. (aacrjournals.org)
Common1
HLA B7-DR15-DQ6 is a representation(by serotype) of a common HLA haplotype found in Western Eurasia. (wikipedia.org)
Population1
HLA B7-DR15-DQ6 was found to have an association with postmenopausal osteoporosis in a Greek population. (wikipedia.org)
Properties2
Subgroups and serotypes are differentiated from each other by their biochemical characteristics (eg, ability to ferment D-mannitol) and antigenic properties. (medscape.com)
Bacterial toxins can be single proteins or oligomeric protein complexes that are organized with distinct AB structure-function properties. (springer.com)
Peptide1
High cell surface expression and peptide binding affinity of HLA-DQA1*05:03, a susceptible allele of neuromyelitis optica spectrum disorders (NMOSD). (nih.gov)
Alleles1
HLA alleles and sustained peanut consumption promote IgG4 responses in subjects protected from peanut allergy. (nih.gov)
Antibody2
Although this article discusses agammaglobulinemia and hypogammaglobulinemia, the emphasis is on selective Ig deficiencies, including the decreased production of IgA and the various IgG subclasses and impaired antibody responses to specific antigens such as polysaccharide proteins present on certain bacteria. (medscape.com)
Methods: PWH from a previous population-based study, the Botswana Prevention Combination Project, which enrolled adults in 30 communities across Botswana (2013-2018), were screened for HBV surface antigen (HBsAg) and HBV core antibody (anti-HBc). (bvsalud.org)
Antibodies3
The importance of IgG-subclass deficiency is reflected in the isotypes of IgG antibodies produced against microbial antigens. (medscape.com)
Antibodies against pneumococcal polysaccharide antigens are predominantly IgG2 and, to a lesser degree, IgG4. (medscape.com)
The haplotype can be written in an extended form covering the major histocompatibility loci as follows: HLA Cw*0702 : B*0702 : DRB1*1501 : DQA1*0102 : DQB1*0602 The older literature may describe this haplotype in two different ways. (wikipedia.org)
HLA-DQA1 belongs to the HLA class II alpha chain paralogues. (nih.gov)
Association between the HLA-DQA1 rs1391371 risk allele and chronic rhinosinusitis. (nih.gov)
Genes1
Antigens encoded by the genes in the group II took part in the rejection of transplanted tumors and other tissues. (slideshare.net)
The other B7-DR2-DQ1 stems from the fact that DQ1 is an alpha chain serotype that is now covered by the beta chain type DQ5 and DQ6 (DQ1 pairs with DQ5 and DQ6 by cis-haplotype pairing). (wikipedia.org)
Major1
There are two major subhaplotypes one that is preceded on its telomeric side by HLA A*0301 and the other by HLA A*0201. (wikipedia.org)
Association2
HLA B7-DR15-DQ6 was found to have an association with postmenopausal osteoporosis in a Greek population. (wikipedia.org)
Association of HLA-DQ Heterodimer Residues -18β and β57 With Progression From Islet Autoimmunity to Diabetes in the Diabetes Prevention Trial-Type 1. (nih.gov)