• Synthesis, spectroscopic, cyclic voltammetry properties and molecular structure of the thiocyanato-N meso-tetratolylporphyrinato zinc(II) ion complex. (icmub.com)
  • Recently, the group of Professor Dorota Gryko (Polish Academy of Sciences, Warsaw, Poland) described the vitamin B12-photocatalyzed cyclization of N -tosyl amines carrying an ω-bromoalkyl and an allyl group, which occurs with subsequent C- dicarbofunctionalization in the presence of acrylic acid derivatives or acrylonitrile, leading to the corresponding cyclic amines. (thieme.de)
  • UNIVERSITY OF BELGRADE FACULTY OF CHEMISTRY Afya A. Baroud SYNTHESIS, CHARACTERIZATION AND CYTOTOXICITY OF BIS(BIPYRIDINE) RUTHENIUM(II) COMPLEXES WITH PICOLINIC ACID DERIVATIVES Doctoral dissertation Belgrade, 2017. (documents.pub)
  • If the destructive σ-interference effect is to benefit from the broad range of complex molecules available through modern organic synthesis, different classes of saturated systems with the effect need to be explored. (rsc.org)
  • A base-mediated protocol enables the synthesis of imines and amines from N -phenylureas and alcohols in good yields under air. (organic-chemistry.org)
  • This protocol is as an efficient alternative to conventional methods for the synthesis of imines and amines. (organic-chemistry.org)
  • Professor Gryko said: "We demonstrated that nature native cobalt complex - vitamin B12 - and light as the source of energy can facilitate the synthesis of complex and valuable organic compounds, including pyrrolidines and piperidines. (thieme.de)
  • Diethanolamine is used in logical chemistry as a reagent as well as a set fluid for gas chromatography to uniquely maintain and divide alcohols, diols, amines, pyridines, quinolines, piperazines, thiols, thioethers as well as water. (zspharmac.com)
  • In combination with polymer-supported cyanoborohydride (PSCBH), a one-pot oxidation-imine formation-reduction sequence enables alcohols to be converted directly into both secondary and tertiary amines. (organic-chemistry.org)
  • Imines and secondary amines were synthesized selectively by a Pd-catalyzed one-pot reaction of benzyl alcohols with primary amines. (organic-chemistry.org)
  • The reactions did not require any additives and were effective for a wide range of alcohols and amines. (organic-chemistry.org)
  • Iron-catalyzed aerobic oxidative reactions of primary amines, secondary amines, benzylamines with anilines, and alcohols with amines in the presence of air as the economic and safe oxidant, provide several direct, practical, and greener approaches for the preparation of useful imines. (organic-chemistry.org)
  • The impact of the metal size and Lewis acidity on the polymerization activity of group 13 metal complexes was studied, and it was shown that, within the same ligand family, indium complexes are far more reactive and selective than their gallium analogues. (americanelements.com)
  • To this end, gallium and aluminum complexes supported by a tridentate diaminophenolate ligand, as well as gallium complexes supported by N,N'-ethylenebis(salicylimine)(salen) ligands, were synthesized and compared to their indium analogues. (americanelements.com)
  • Using the tridentate ligand set, it was possible to isolate the gallium chloride complexes 3 and (±)-4 and the aluminum analogues 5 and (±)-6. (americanelements.com)
  • In this article, we examine the single-molecule junction properties of saturated heterocyclic cyclohexane derivates, 1,4- dithiane , 1,4- piperazine and 1,4-diazabicyclo[2.2.2]octane, C222-diaza , also known as DABCO, shown in Scheme 1 . (rsc.org)
  • 1-(Methyl-D3)piperazine 2HCl, a remarkable chemical compound, is characterized by its deuterium-labeled methyl group and its association with piperazine, a bicyclic heterocyclic amine. (clearsynth.com)
  • 1,2-Ethylenediamine readily forms heterocyclic imidazolidine derivatives, because of its bifunctional nature, having two amines. (atamanchemicals.com)
  • This is then hydrolyzed by a water molecule to give an unstable vicinal terminal hydroxyl amine which rapidly decomposes to yield the de-methylated lysine H3K4 molecule and formaldehyde, which diffuses away and is subsequently metabolized by aldehyde dehydrogenase. (wikipedia.org)
  • A set of promising moieties (piperidineethanol, quinuclidine, TMEDA, and methyl derivatives of diethanolamine, imidazole, morpholine and piperazine) had similar [Au]R/Cm values to the commercial IEX resins Dowex-1, IRA-410 and Amberlite A26 (-10 mmol/mol). (edu.au)
  • Neat non-volatile amines react efficiently with various aromatic aldehydes in the absence of any catalyst or solvent, to give imines after a reaction time of eight minutes under microwave irradiation. (organic-chemistry.org)
  • A Comparison of Gallium and Indium Alkoxide Complexes as Catalysts for Ring-Opening Polymerization of Lactide. (americanelements.com)
  • [0002] It is generally known that aliphatic nitrites, which may be substituted by further functional groups, can be hydrogenated in the presence of catalysts to form the corresponding amines. (patentsencyclopedia.com)
  • this study shows that indium halide complexes are less Lewis acidic than their aluminum and gallium analogues. (americanelements.com)
  • Density functional theory calculations show that the Mulliken charges for the indium complexes are higher than those for the gallium analogues. (americanelements.com)
  • It has been demonstrated that the composition and length of the linker play a crucial role in influencing the spatial orientation and physicochemical properties of the POI-PROTAC-E3 ternary complex. (musechem.com)
  • Due to the improved hit rate in forming ternary complexes and subsequent degradation of the POI, flexible linkers are often the preferred choice in the early stages of PROTAC discovery. (musechem.com)
  • Tris(2,2,2-trifluoroethyl)borate [B(OCH 2 CF 3 ) 3 ] is a mild and general reagent for condensation of amides or amines with carbonyl compounds providing N -Sulfinyl, N -toluenesulfonyl, N -(dimethylamino)sulfamoyl, N -diphenylphosphinoyl, N -(α-methylbenzyl), and N -(4-methoxyphenyl) aldimines at room temperature. (organic-chemistry.org)
  • Desogestrel binds intracellular progesterone receptors in progesterone responsive tissue and the resultant complex interacts with DNA and results in either gene transcription or gene repression. (medindex.am)
  • The gold and copper thiosulfate complexes, along with the thiosulfate, trithionate and tetrathionate anions were modelled using ab-initio density functional theory (DFT). (edu.au)
  • Find complete chemical information for 1-​(METHYL-​D3)​PIPERAZINE 2HCL . (clearsynth.com)
  • 1-​(METHYL-​D3)​PIPERAZINE 2HCL in Bulk is primarily used in Pharmaceutical Industry and Drug Discovery. (clearsynth.com)
  • Evogliptin ((R)-4-((R)-3-amino-4-(2,4,5-trifluorophenyl)butanoyl)-3-(tert-butoxymethyl) piperazine-2-one)) is a highly potent selective inhibitor of dipeptidyl peptidase IV (DPP4) that was approved for the treatment of type 2 diabetes in South Korea. (inrae.fr)
  • In this study, we report the crystal structures of Evogliptin, DA-12166, and DA-12228 (S,R diastereomer of Evogliptin) complexed to human DPP4. (inrae.fr)
  • A highly conserved lysine (Lys661 in LSD1) at the active site in FAD-dependent amine oxidases is believed to assist in this reaction. (wikipedia.org)
  • A common reaction scheme was employed for most preparations, via treatment of the exhaustively chloromethylated resin substrate with excess amine in dimethylformamide. (edu.au)
  • 20. The process according to claim 12, wherein TETA or diethylenetriamine (DETA) and optionally further ethylene amines which are comprised as by-products in the reaction product obtained in each case are isolated after the hydrogenation. (patentsencyclopedia.com)
  • MIPs can function under extreme conditions of pH, temperature and complex environment. (intechopen.com)
  • For this purpose, also, besides the literature review investigates the effect of some operational parameters such as temperature, pressure, amine concentration, solution flow rate, and the adsorbent loading on the CO 2 removal efficiency and CO 2 capture capacity. (ac.ir)
  • 1,2-Ethylenediamine is a clear and colorless product at normal temperature and pressure which has a characteristic smell of an amine. (atamanchemicals.com)
  • Made use of as a complexing representative for silver, cadmium, lead, along with zinc plating. (zspharmac.com)
  • [ 5 ] Long-term use can lead to a depletion of biogenic amine stores and a paradoxical reverse effect of the drug-a wash out. (medscape.com)
  • The results demonstrated that the flow rate of liquid and concentration of amine has a positive effect on the removal efficiency and the CO 2 flow rate has a negative effect. (ac.ir)
  • A set of 48 novel ion-exchange (1EX) resins bearing a range of amine and quaternary ammonium moieties were prepared on a polystyrene-divinylbenzene substrate. (edu.au)
  • Initially, the functional monomer forms a complex and, after polymerization, their functional groups are held by the highly crosslinking polymeric structure. (intechopen.com)
  • That species is then hydrolytically cleaved by water to give free amine and cinnamaldehyde fragments. (wikipedia.org)
  • 1,2-Ethylenediamine is frequently used in soaps and detergents to form complexes with calcium and magnesium ions in hard water to improve the cleaning efficiency. (atamanchemicals.com)
  • The reduced FAD state is converted back to its normal resting oxidized state by molecular oxygen with the production of hydrogen peroxide while the larger cinnamaldehyde fragment, rather than diffusing away from the active site, is able to react in situ with the oxidized FAD to form a stable covalent adduct, effectively locking the LSD1/CoREST complex into a permanently inactivated state. (wikipedia.org)
  • Carbon Sequestration: We are evaluating the formation of nitrosamine and nitraminecarcinogens from amine-based carbon capture, as well as techniques to destroy any of these byproducts that form. (stanford.edu)
  • Vitamin B12 (cyanocobalamin) is a Co(III) complex used by nature as a cofactor for a number of key enzymatic transformations, which plays a key role in the functioning of living cells. (thieme.de)
  • The phenylethylamine structure of amphetamines (see the image below) is similar to catecholaminergic, dopaminergic, and serotonergic agonists (biogenic amines), which may explain their actions. (medscape.com)
  • Once the mast cell-antibody-antigen complex is formed, a complex series of events occurs that eventually leads to cell degranulation and the release of histamine (and other chemical mediators) from the mast cell or basophil. (wikidoc.org)
  • They inhibit specific transporters responsible for reuptake of biogenic amines from the synaptic nerve ending and presynaptic vesicles. (medscape.com)
  • VHL is part of the E3 ubiquitin ligase complex CUL2-RBX1-ElonginB-ElonginC-VHL, consisting of two structural domains with specific binding sites. (musechem.com)
  • This "casting a wide net" approach enables the exploration of diverse conformations, maximizing the potential for formation of ternary complexes with the POI and E3 ligase. (musechem.com)
  • In addition, the regulatory requirements are more complex when the agents are used in combination, since the safety profile of each drug needs to be demonstrated before clinical trials, and this can be further delayed due to regulatory and IP issues, in particular if the two drugs are being developed by different companies [ 1 ]. (biomedcentral.com)