Complex biological assay. Medical search. Frequent questions

With current in vitro screening assays now representing a $1.4B market with a predicted 12% annual growth rate, we believe we possess a product capable of significantly impacting the chemical/drug screening market and, here in particular, advancing our understanding of cytotoxic chemical biotransformations as they pertain to public health and consumer safety. (inknowvation.com)

The range of available testing services include cell-based potency assays, bioassays and binding assays, as well as physicochemical and structural analyses, enabling customers to benefit from a fully integrated package. (manufacturingchemist.com)
Senior Scientist Helen Hsu, Ph.D. describes how, with our custom binding assays, and supported with our comprehensive off-the-shelf Fc gamma receptor binding assays, we can help you optimize your mAb production, from clone development through upstream and downstream processes. (sigmaaldrich.com)

The role of potency assays will also be addressed. (frontiersin.org)

A senior research scientist position is available at the Marine Biological Laboratory in Woods Hole MA to continue our study on the crystal structures of blood coagulation proteins, particularly Factor VIII (Structure. (sbgrid.org)
The company provides a comprehensive range of testing for innovator molecules available either as off-the-shelf assays or custom assay development for more complex proteins. (manufacturingchemist.com)
Macromolecules such as proteins, RNA, and DNA do not act alone, but interact to form complex networks, the "interactome" network. (dana-farber.org)
We study the interaction between proteins in biological fluids as well as single proteins to nanomaterials of different kinds. (lu.se)
She also developed multiplex assays to quantify proteins associated with different diseases, which were then used to screen clinical patient cohorts. (lu.se)

This new paradigm would be anchored by in vivo monitoring of complex sets of molecular biomarkers rather than in vitro screening of single targets (the term in vitro is used throughout this article to mean a biochemical reaction carried out in a laboratory vessel using isolated reagents, as opposed to another common usage of in vitro that refers to cells grown in cultured conditions). (ddw-online.com)
Assay biological specimens for biomarkers of disease. (nih.gov)
Founded in 1998 and headquartered in Cambridge, UK, Abcam offers the scientific community highly validated antibodies, reagents, biomarkers and assays to address targets in biological pathways that are critical for advancing drug discovery, life sciences research, and diagnostics. (onenucleus.com)

On the other hand, older generation qualitative assays, especially bioassays, may be much more gross and less quantitative (e.g., counting death or dysfunction of an organism or cells in a population, or some descriptive change in some body part of a group of animals). (wikipedia.org)

Serum samples from case-patient 2 did not contain antibodies detectable by either assay. (cdc.gov)
The Wampole Laboratories (Wampole) H. pylori IgG Enzyme-Linked Immunosorbent Assays (ELISA) is intended for the detection and qualitative determination of IgG antibodies to Helicobacter pylori in human serum. (cdc.gov)
Providing the research and clinical communities with tools and scientific support, the Company offers highly validated antibodies, assays, and other research tools to address important targets in critical biological pathways. (onenucleus.com)

Mass spectrometry, specifically tandem mass spectrometry (MS/MS) is the method of choice to mine complex samples for new natural products. (drexel.edu)
Support from the Swedish National Infrastructure for Biological Mass Spectrometry (BioMS) and the SciLifeLab, Integrated Structural Biology (ISB) platform, is gratefully acknowledged. (lu.se)
Dr. Rezeli has 15 years of experience in biological mass-spectrometry. (lu.se)
She is associated with the Swedish National Infrastructure for Biological Mass Spectrometry, and a member of the Working group on Protein Misfolding and Aggregation Diseases in B/D HPP. (lu.se)

Enzyme linked immunosorbent assays (ELISA) rely on the ability of biological materials, (i.e. antigens) to adsorb to plastic surfaces such as polystyrene (solid phase). (cdc.gov)

Its biological activity has been verified using cellular assays. (invivogen.com)
The complexities of biological manufacturing, the large size of the molecules, and the product heterogeneity introduced by cellular expression systems present significant challenges to measuring the quality of a biologic drug. (sigmaaldrich.com)
The strategy followed at the Center is to generate models of the human interactome to answer such questions as how complex cellular systems relate to biology and how perturbations of cellular networks lead to cancer. (dana-farber.org)
Operetta® CLS™ High-Content Analysis System & Columbus™ Software: The Operetta CLS system enables scientists to gain deep biological insight into disease from common assays and complex applications using advanced cellular models, and to identify even subtle phenotypic changes through sensitive imaging and intuitive data analysis. (technologynetworks.com)

When antigens bound to the solid phase are brought into contact with a participant's serum, antigen-specific antibody, if present, will bind to the antigen on the solid phase forming antigen-antibody complexes. (cdc.gov)
A variety of sero- complexes, serum amyloid, rheumatoid logical tests for the detection of anti-leish- factors and autoantibodies. (who.int)

If the assay involves exogenous reactants (the reagents), then their quantities are kept fixed (or in excess) so that the quantity and quality of the target are the only limiting factors. (wikipedia.org)

Synthace's cloud-based platform Antha® enables automation of design of experiments (DOE) to optimize complex biological processes and assays. (jmp.com)
With the advent of laboratory automation and more rigorous analytical techniques, scientists now have the opportunity to ask more complex questions to understand and develop more complex biological systems. (jmp.com)
Automation plays a vital role in this process, enabling high throughput screening of cell-based assays. (tecan.com)
The integration of such systems for series of complex individual operations on droplets has offered a solution to the necessary miniaturization and automation of individual biological assays. (selectbiosciences.com)
Using the LANCE Ultra kits' unique combination of ULight Acceptor and Europium Eu chelate donor pairs, researchers can perform a wider variety of highly sensitive, automation friendly assays to speed and simplify the screening process. (technologynetworks.com)
Our lab automation for high-throughput, high-content screening include scientists and engineers who can customize our instruments, as well as automate entire workflows to meet the specific needs of your assay, method, or protocol. (moleculardevices.com)
New advanced tools for imaging and analysis, as well as assay automation are critical for increased quality of information, throughput, and precision of complex biological models. (moleculardevices.com)

We will show how by combining droplet-based microfluidic systems and clinical advances in molecular diagnostic we have developed an original method to perform millions of single molecule PCR in parallel to detect and quantify a minority of mutant sequences within a high quantity of non-mutated sequences in complex mixture of DNA with a sensitivity and precision that was unreachable by conventional procedures. (selectbiosciences.com)
With our lab-on-a-chip systems we aim to make biological and diagnostic assays simpler, more sensitive and less error prone. (microfluidic-chipshop.com)
KAtex est un simple supplément pour le diagnostic de la leishmaniose viscérale, en particulier sur le terrain, et un test complémentaire pour le diagnostic de la leishmaniose viscérale dans les cas à frottis négatif ayant des résultats positifs au test d'agglutination directe. (who.int)
Al- direct demonstration or cultivation of the though a number of papers have reported causative organism, remain the definitive the existence of circulating antigens and laboratory diagnostic method for VL, sero- immune complexes in VL [ 16-19 ], none of diagnostic methods are needed to over- them has led to a useful antigen detection come the diagnostic difficulties assay for VL. (who.int)
She has participated in and led several proteomic and multi-omic studies, which were primarily aimed at understanding the complex biological processes underlying development and heterogeneity of various diseases, such as Alzheimer´s disease and various cancers, as well as exploring possible new diagnostic and therapeutic options. (lu.se)

Assays can be very diverse, but generally involve the following general steps: Sample processing and manipulation in order to selectively present the target in a discernible or measurable form to a discrimination/identification/detection system. (wikipedia.org)

An assay is an investigative (analytic) procedure in laboratory medicine, mining, pharmacology, environmental biology and molecular biology for qualitatively assessing or quantitatively measuring the presence, amount, or functional activity of a target entity. (wikipedia.org)
Molecular complexes of topo I and topo II inhibitors from camptothecin and flavonoid families with model DNA oligomers. (science24.com)
Molecular profiling using genomic approaches is becoming an important complement to this process and may eventually become a new paradigm for drug discovery that is based on complex biomarker sets, or molecular profiles, that are monitored in vivo. (ddw-online.com)
We have two announcements for this month: a position available at the Marine Biological Laboratory in Woods Hole, Massachusetts and a free workshop on molecular dynamics held at Stanford University in February. (sbgrid.org)

The resulted complexes were fully characterized by different techniques such as 1 H NMR, UV-vis, XRD, DSC and SEM, and they were biologically assayed in comparison with the pure compound in several biological systems. (rsc.org)
Before the 20th century, biological warfare took three main forms: (1) deliberate poisoning of food and water with infectious or toxic material, (2) use of microorganisms or toxins in some form of weapon system, and (3) use of biologically inoculated fabrics. (medscape.com)

In one run of the assay M molecules are tested, generating 2 M N data points. (physicsforums.com)
The assay is often repeated multiple times on certain molecules. (physicsforums.com)
A step towards rapid radiolabeling of complex biological molecules for PET imaging. (cea.fr)

Biological assays to test the cytotoxicity of the compound 1b combined with electroporation were performed to determine its potential for future medical applications in cancer treatment. (hindawi.com)
Considering as evaluation metrics standard plate-, assay- or compound statistics on the final results, we assess the generalizability and importance of the selected features by use of automated machine learning (AutoML) to achieve an unbiased evaluation across methods. (genedata.com)
In addition, methods to increase throughput, such as automated organoid assays and compound screening, are presented. (moleculardevices.com)

Various assays and biological studies showed evidence of comparable cytotoxicity and mechanism, demonstrating that altering the substitution of the isonitrile ligand doesn't significantly impact the bioactivity of the complex. (rsc.org)
Critically, the colocalization of the Re and I maps for I-TRIP samples indicate that the isonitrile ligand remains bound as a part of the Re complex inside the cells. (rsc.org)

Small enough to fit the palm of the hand the so-called "lab on a chip" or micro total analysis systems (TAS) employs miniaturization of biological separation and assay techniques to an extent that multiple and complex analyses can be done on a chip. (medgadget.com)

Inhibitors of bacterial RNA polymerase transcription complex" by Daniel S. Wenholz, Michael Miller et al. (edu.au)

Product Characterization Scientist, Rachel Wood, introduces the multiplexed cytokine release assay. (sigmaaldrich.com)
A highly sensitive assay that requires low sample volumes to measure the cytokine release activity induced by your mAb. (sigmaaldrich.com)
No. 559603), which is specially formulated for assay of cytokine in complex fluids. (bdbiosciences.com)

However, because almost all disease processes are complex and multi-factorial, drug discovery efforts that are anchored in defining the effect of compounds on isolated targets outside their natural microenvironment have obvious drawbacks. (ddw-online.com)
Work at the Center maps the human interactome network with systematic protein-interaction assays, aiming to deepen understanding of complex functional interactions and biological processes relevant to cancer. (dana-farber.org)

Synthesis, in vitro transcription inhibition assays, and biological testing of the hybrids identified a range of potent anti-transcription inhibitors with activity against a range of pathogenic bacteria with MICs as low as 3.1 μM. (edu.au)

e.g., pre-analytic steps in medical laboratory assays may contribute 32-75% of all lab errors. (wikipedia.org)
A joint appointment at the Marine Biological Laboratory and Harvard Medical School is anticipated. (sbgrid.org)
Instruments powerful enough to meet the required speed, sensitivity, and selectivity requirements often do not function well outside of rigorously controlled laboratory conditions and are usually very complex and expensive. (cdc.gov)
The German-American physician Anton Dilger established a secret biological laboratory in Chevy Chase, Maryland, with the intent to grow the causative agents of anthrax and glanders. (medscape.com)

These technologies allow researchers to automate and improve the efficiency of their workflows across liquid handling, assays, big data and informatics processing, high content imaging and nucleic acid extraction. (technologynetworks.com)

In this blog, we explore what it takes to tame automated cell imaging assays, and take back control of kinetic experiments to get reliable results more quickly, with fewer errors and less aggravation. (tecan.com)
Biostatistics areas of interest include development of advanced statistical techniques and methodologies for design of biological experiments, collection and analysis of the data from those experiments and interpretation of, and inference from, the results. (nih.gov)
This complex problem will be addressed by determining the distribution and chemical composition of the DOM pool and selected metal species and their speciation in the different systems and by performing incubation experiments in the field and in the lab. (europa.eu)
In situ and lab experiments will be performed to determine the alterations in the DOM-metal complex upon exposure to UV radiation. (europa.eu)
In bio-assay experiments, the UV-induced changes in the bioavailability of selected metal species will be investigated. (europa.eu)
Micro- and mesocosm experiments at selected sites will be performed to investigate the complex interaction between the DOM-metal complex and the microplankton component of the food web in the presence of UV radiation. (europa.eu)
During World War II, the Japanese operated a secret biological warfare research facility in Manchuria and carried out human experiments on Chinese prisoners. (medscape.com)

Thus, reading of an assay may be noisy and involve greater difficulties in interpretation than an accurate chemical titration. (wikipedia.org)
Biological systems can often be quite noisy, and a lot of assays tend to be very labor- and resource-intensive," explains Michael Sadowski, PhD, Head of Bioinformatics at Synthace. (jmp.com)

However, assays typically involve biological material or phenomena that are intrinsically more complex in composition or behavior, or both. (wikipedia.org)
The behavior of mesenchymal stem cells from an umbilical cord vein was evaluated using a 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide (MTT) assay, a mineralization assay, and an alkaline phosphatase activity assay and by carrying out a quantitative real-time polymerase chain reaction for osteogenic markers. (biomedcentral.com)

Nematic liquid crystals (NLCs) are complex non-Newtonian fluids - anisotropic fluids with a degree of long-range orientational ordering. (fluids.ac.uk)

The difference in the assay outcome is used to deduce the unknown quality or quantity of the target in question. (wikipedia.org)
or use data science methods and tools to deduce information about biological systems. (nih.gov)

Of interest are development of computational and mathematical algorithms and tools, modeling techniques and approaches for understanding the complexity of biological systems, and utilization of big datasets and data science methods for model construction. (nih.gov)
We compare 12 state-of-the-art feature selection methods (both supervised and unsupervised) by systematically testing them on two HCS datasets from drug screening imaging assays of high practical relevance. (genedata.com)

Some assays (e.g., biochemical assays) may be similar to chemical analysis and titration. (wikipedia.org)
For assay of currency coins this literally meant analysis of the purity of the gold or silver (or whatever the precious component) that represented the true value of the coin. (wikipedia.org)
An assay (analysis) is never an isolated process, as it must be accompanied with pre- and post-analytic procedures. (wikipedia.org)
Exploiting HCS to its full potential traditionally requires extracting a high number of features from the images to capture as much information as possible, then performing algorithmic analysis and complex data visualization in order to render this high-dimensional data into an interpretable and instructive information for guiding drug development. (genedata.com)
two protein structures were solved, and insights into their regulation and biological roles were gained through gene expression analysis and enzymatic assays on complex biomass. (proteopedia.org)
95% pure as determined by SDS-PAGE analysis, and an absorbance assay based on the Beers-Lambert law. (bdbiosciences.com)
The BD ® AbSeq Assay enables expression analysis of CD11c and CD5 markers in chronic lymphocytic leukemia (CLL) samples. (bdbiosciences.com)
Six-week-old organoids were treated with various compounds followed by the live/dead assay and advanced image analysis to assess effects of treatment. (moleculardevices.com)

As your characterization partner we can provide expert guidance on the biological components of your antibody drug conjugate (ADC) - conducting safer, more reliable, and faster testing that helps to expedite product quality decisions at critical junctures. (sigmaaldrich.com)

LANCE® Ultra TR-FRET Assay Kits: With over 60 new, easy-to-use kits for oncology, immunology, metabolic, neuro and biotherapeutic targets, these innovative assays enable researchers performing drug discovery to achieve highly sensitive and reliable results in an extremely short amount of time. (technologynetworks.com)

Biological warfare became more sophisticated against both animals and humans during the 20th century. (medscape.com)

Finally, the in vitro model we have described should serve as a useful system to investigate the complex interactions that appear to operate in vivo within the biofilm-antifungal interphase. (who.int)
Trace metals originating from anthropogenic activities are largely transported via rivers into the coastal environment and undergo complex physico-chemical interactions with DOM. (europa.eu)
All the data acquired are directly entered in an existing model, which will be expanded significantly to allow predictions on the future development of the physico-chemical interactions in the DOM-metal complex model and its interaction with the planktonic component of the food web in European waters. (europa.eu)
Ribosome interactions anchor the Sec61/TRAP complex in a conformation that renders. (lu.se)
Ribosome interactions anchor the Sec61/TRAP complex in a conformation that renders the ER membrane locally thinner by significantly curving its lumenal leaflet. (lu.se)

The development of platinum-drug resistance in cancer patients, the general toxicity and severe side effects of platinum drugs however required a different approach in the research of anticancer metal complexes [ 2 ]. (hindawi.com)
New drug research uses biochips for drug assays and also to test them for toxicity. (medgadget.com)
Drug discovery efforts that focus on in vitro targetbased screening benefit from the advantage of having a relatively simple binary assay with which to define success or failure of an individual drug candidate. (ddw-online.com)
This allows drug developers to fast-track complex bioassay development using our platform methods. (manufacturingchemist.com)
Abcam is expected to operate as a standalone operating company and brand within Danaher's Life Sciences segment, furthering Danaher's strategy to help map complex diseases and accelerate the drug discovery process. (onenucleus.com)
The complexity of 3D assays remains a hurdle for the wider adoption of organoid models in research and drug screening. (moleculardevices.com)

The work will include preparation of protein-protein complexes, biological assay, crystallization, and structure determination. (sbgrid.org)
The product can be reconstituted in sterile neutral buffer containing not less than 0.5 - 10 mg/ml carrier protein such as human or bovine albumin, aliquoted and stored at -80°C. For in vitro biological assay use, we recommend carrier-protein concentrations of 0.5 - 1.0 mg/ml. (bdbiosciences.com)
In cells, the majority of Sec61 is stably associated with a heterotetrameric membrane protein complex, the translocon-associated protein complex (TRAP), yet the mechanism by which TRAP assists in polypeptide translocation remains unknown. (lu.se)

Assays in high commercial demand have been well investigated in research and development sectors of professional industries. (wikipedia.org)
In the face of increasingly complex methodologies and research questions, a more comprehensive approach is required. (jmp.com)
Synthace offers a new approach, by applying the principles of DOE, to reduce experimentation time and make biological research more reproducible. (jmp.com)
The bottom line is that they still very much need to use animals in this area of research since 'alternative' assays simply can't model complex biological systems yet, but they clearly are pressing ahead to make whatever gains they can using available technology. (understandinganimalresearch.org.uk)
Clean, document, disseminate, archive (including storage of biological specimens for future study), and promote the Wave VI data to the scientific community for aging research. (nih.gov)
In today's complex research setting, speed and efficiency are critical to achieving scientific breakthroughs. (technologynetworks.com)
Introduction The research of Hatch (1) has greatly increased our understand- ing of the use and potential limitations of biological markers for adverse reproductive effects. (cdc.gov)

Unfortunately, existing field assay methods are typically inadequate because they lack the selectivity and sensitivity needed to provide reliable information. (cdc.gov)

Droplet-based microfluidics has led to the development of highly powerful systems that represent a new paradigm in High-Throughput Screening where individual assays are compartmentalized within microdroplet microreactors. (selectbiosciences.com)

To cope with the complex task of developing such systems, we adapt standard assay steps to the special requirements of the microfluidic surrounding. (microfluidic-chipshop.com)
Independent of how different your specific assays themselves are, the underlying principle and general steps to transfer the assay on chip usually have similar requirements and are part of microfluidic ChipShop's daily business. (microfluidic-chipshop.com)
To cope with these tasks, microfluidic ChipShop's biological and chemical laboratories are well equipped and experienced application teams are at hand. (microfluidic-chipshop.com)
This has the potential of creating ultra-low-cost acoustofluidics devices, capable of carrying out complex microfluidic processing of samples for applications in flexible and wearable healthcare monitoring. (fluids.ac.uk)

Whether you are testing cell pools or isolated clones, we have compliant mAb-based assays to suit the level of characterization you require to understand the function and critical quality attributes of your biotherapy. (sigmaaldrich.com)
Senior Scientist, Agata Burzawa, MSc, describes how designing cell-based assays to help our clients understand the complex biological functions of the therapy they are developing as a part of product characterization. (sigmaaldrich.com)

Development of new or improved instruments, methods, and related software to elucidate 3D structures of macromolecules and macromolecular complexes. (nih.gov)
For this reason, inuloxin A was complexed with β-cyclodextrins by using three different methods, i.e. , kneading, co-precipitation and grinding. (rsc.org)
To meet this need, a wide range of field screening methods for identifying chemical, biological, and nuclear materials is presently being marketed and used. (cdc.gov)

Biological weapons include any organism or toxin found in nature that can be used to incapacitate, kill, or otherwise impede an adversary. (medscape.com)

But behind every great imaging assay, pity the poor scientist grappling with the demands of biological variability and complex kinetic assays. (tecan.com)

We also want to combine several assay steps, which are conventionally conducted in different systems, in one device. (microfluidic-chipshop.com)

By combining a decrease of assay volume and an increase of throughput, this technology goes beyond the capacities of conventional screening systems. (selectbiosciences.com)
We address the complex interaction between metals, dissolved organic matter (DOM), solar radiation and its influence on a diverse range of European aquatic systems. (europa.eu)
The expected outcomes are scientific publications and a model with the goal to allow predictions on the future development of the interaction of the DOM-metal complex in a variety of European aquatic systems under increased UV radiation scenarios. (europa.eu)
The potential spectrum of bioterrorism ranges from hoaxes and actual use of agents by individuals or groups against others, to state-sponsored terrorism that employs biological warfare (BW) agents and delivery systems that can produce mass casualties. (medscape.com)

Life scientists have often taken a manual, one-factor-at-a-time approach to experimentation that omits critical insights into how simultaneous changes in multiple factors can affect the biological outcomes. (jmp.com)

Such industrial-scale assays are often performed in well-equipped laboratories and with automated organization of the procedure, from ordering an assay to pre-analytic sample processing (sample collection, necessary manipulations e.g. spinning for separation, aliquoting if necessary, storage, retrieval, pipetting, aspiration, etc. (wikipedia.org)
Effective use of hierarchical lines of evidence relies on consideration of the rele- vance and potency of assays, organization of assays by mode of action, and better assay validation. (cdc.gov)

La concentration sérique pour ces facteurs chez les femmes non encein- tes était similaire à celle des femmes enceintes en bonne santé. (who.int)
Toutefois, la concentration sérique était significativement plus élevée en présence d'une prééclampsie bénigne ou grave par rapport aux grossesses normales et significativement plus élevée pour les prééclampsies graves par rapport aux prééclampsies bénignes. (who.int)

This is followed by the addition of goat anti-human IgG conjugated with horseradish peroxidase, which then binds to the antibody-antigen complexes. (cdc.gov)

As an example of one of the complex transformations on this pathway, the figure below shows the structure of the pyrimidine synthase catalyzing the complex rearrangement of aminoimidazole ribotide (left) to the thiamin pyrimidine (right). (tamu.edu)

A wide range of biological materials - from extracellular matrix components and platelet lysates to stem cells - can be used to induce targeted tissue regeneration, but require careful formulation, extraction and purification for clinical use. (tecan.com)
The other members of the Mycobacterium tuberculosis complex (MTC) or the nontubercular mycobacterium (NTM) produces similar diseases which cannot be differentiated from tuberculosis by clinical symptoms and signs. (openmicrobiologyjournal.com)

Lastly, we present the solved crystal structure of the nsp14-MTase complexed with SS148, a potent inhibitor of methyltransferase activity at the nanomolar level (IC50 value of 70 ± 6 nM). (bvsalud.org)

Can the 'standard deviation' or the assay itself be calculated from these data, as if they were direct, repeated measurements? (physicsforums.com)
Including gene expression data (ref), network modeling (ref), DNA copy number data (ref), and massively parallel reporter assays(ref). (lu.se)

A consortium of researchers, including SPI/DMTS metabolomics specialists, presents PeakForest, a database of NMR and mass spectra, which provides storage and annotation services for spectra of reference compounds and metabolic profiles of biological matrices. (cea.fr)
Researchers in the US and Australia developed a tricarbonyl Re isonitrile polypyridyl complex fac-[Re(CO)3(dmphen)(para-tolyl-isonitrile)]+, where dmphen = 2,9-dimethyl-1,10-phenanthro-line, called TRIP for short. (rsc.org)

As with any multi-step information handling and transmission system, the variation and errors in reporting final results entail not only those intrinsic to the assay itself but also those occurring in the pre-analytic and post-analytic procedures. (wikipedia.org)

The most commonly studied complexes are based around a Re(I) tricarbonyl core with the other three binding sites occupied by ligands of varying complexity. (rsc.org)

We explore the properties of these factors in biological assays. (drexel.edu)

Verification of biological assay on atomic coordinates level. (science24.com)

In vitro diagnostics (IVD) is central to the provision of healthcare globally, and is estimated to be worth in excess of $8.2 billion (€7.3 billion) a year in China alone.1 Despite this, the Chinese IVD landscape has historically been controlled by large international providers, with few domestic instrumentation and assay suppliers. (tecan.com)
Combining experience, state-of-the-art instrumentation, and fast turnaround times, we provide reliable assays that help control process and product impurities in mAb biologics and push your project forward. (sigmaaldrich.com)

The Begley Group is interested in the mechanistic chemistry and enzymology of complex organic transformations, particularly those found on the vitamin biosynthetic pathways. (tamu.edu)
2014). Prior work has confirmed that ORGANIC resolves the positioning of TFs at high res and provides information on multifactor complexes at binding sites (Kasinathan et al. (eprf.ca)

The unique combination of biological and structural studies at the Department of Immunology & Theranostics, has created a thriving, productive environment and a fruitful collaboration among investigators at City of Hope and at other institutions. (cityofhope.org)

Jennifer Lawson, Product Manager for Testing at Sartorius Stedim BioOutsource, commented: "With our unrivalled experience in biosimilars testing, combined with our proven expertise in NBE assay development, we have developed a panel of assays suitable for mAb characterisation. (manufacturingchemist.com)
Thus, pharmaceutical companies can now work with one contract partner from cell line development to qualification and validation of analytical and biological product characterisation assays. (manufacturingchemist.com)
In 2007 she joined a biotech company in Hungary as a researcher and took part in the development of immune-based multiplex assays in the field of life sciences and healthcare. (lu.se)

Anatomy4

Organisms5

Diseases1

Chemicals and Drugs18

Analytical, Diagnostic and Therapeutic Techniques and Equipment34

Phenomena and Processes32

Disciplines and Occupations9

Anthropology, Education, Sociology and Social Phenomena1

Technology, Industry, Agriculture2

Information Science15

Health Care6

Vitro screen1

Binding Assays2

Potency Assays1

Proteins5

Biomarkers3

Bioassays1

Antibodies3

Mass spectrometry4

ELISA1

Cellular4

Serum2

Reagents1

Automation7

Diagnostic5

Detection1

Molecular4

Biologically2

Molecules3

Compound3

Ligand2

Analyses1

Bacterial1

Cytokine3

Processes2

Synthesis1

Laboratory4

Workflows1

Experiments7

Noisy2

Behavior2

Fluids1

Deduce2

Datasets2

Analysis8

Conjugate1

Targets1

Humans1

Interactions5

Drug6

Protein3

Research7

Typically1

High-throughput1

Microfluidic4

Characterization2

Methods3

Organism1

Scientist1

Combine1

Systems4

Simultaneous1

Organization2

Concentration2

Antigen1

Synthase1

Clinical2

Potent1

Data2

Researchers2

Procedures1

Complexity1

Factors1

Verification1

Instrumentation2

Organic2

Immunology1

Development3