Comorbidity severity of illness index. Medical search. Frequent questions

To explore the potential relationship between erectile dysfunction (ED), low testosterone levels, and the Charlson Comorbidity Index (CCI). (nih.gov)
Martin Meltzer] Well, the authors of the study on pneumonia did adjust for pre-existing medical conditions by using a severity-of-illness scale, called the Charlson Comorbidity Index. (cdc.gov)
Among these 45 persons, 21 (47%) were aged 65 years, and Charlson Comorbidity Index, which included 17 conditions of interest available in EHRs during the 12 months preceding the date of treatment. (cdc.gov)

For example, in longstanding diabetes mellitus, the extent to which coronary artery disease is an independent comorbidity versus a diabetic complication is not easy to measure, because both diseases are quite multivariate and there are likely aspects of both simultaneity and consequence. (wikipedia.org)

9 , 10 The underlying causes of the shorter survival of these patients have remained unclear so far, resulting in uncertainty whether treatment approaches in patients with CLL and comorbidity should focus on the prevention of therapy-related morbidity and mortality or whether the potential loss of disease control associated with such a strategy will offset its net benefits by increasing disease-related morbidity and mortality. (haematologica.org)
The epidemiology of exacerbations of chronic obstructive pulmonary disease (COPD) is reviewed with particular reference to the definition, frequency, time course, natural history and seasonality, and their relationship with decline in lung function, disease severity and mortality. (bmj.com)
0.3 mL/kg/hr).Measurements and main resultsThe primary outcome was hospital mortality, whereas secondary outcomes included prevalence of acute kidney injury and characterization of acute respiratory distress syndrome risk factors and illness severity patterns, in patients with acute kidney injury versus no acute kidney injury. (ox.ac.uk)
0.001) acute kidney injury were independently associated with mortality.ConclusionsThe development of acute kidney injury, even when mild-moderate in severity, is associated with a substantial increase in mortality in patients with acute respiratory distress syndrome. (ox.ac.uk)
This study compares the 100-day mortality of chronic hemodialysis patients with patients without kidney disease with the same disease severity. (eastjmed.org)
Multivariable regression analysis in Model A showed that chronic hemodialysis and critical illness were significantly associated with 100-day mortality, while cardiovascular disease comorbidity was a significant factor only in univariable analysis. (eastjmed.org)
DISCUSSION AND CONCLUSION: Patients undergoing chronic hemodialysis are at a higher mortality risk than those without kidney disease, even with the same severity of coronavirus disease 2019. (eastjmed.org)
Clinicians can predict in-hospital mortality and manage patients more effectively by evaluating the pneumonia severity index scores. (eastjmed.org)
however, all levels of severity carry a high mortality rate if appropriate measures to improve oxygenation and minimize the risk of further lung injury are not taken. (wikidoc.org)
http://cid.oxfordjournals.org/content/47/3/375.long http://www.ncbi.nlm.nih.gov/pubmed/18558884?tool=bestpractice.com The PSI score classifies patients in 5 risk classes associated with the risk of mortality while the CURB-65 score uses 5 variables to calculate severity. (bmj.com)
There is still limited to no evidence on the independent and interactive effects of HIV infection, disease stage, baseline disease severity and other important comorbidities on mortality risk among young children treated for severe acute malnutrition (SAM) in South Africa (SA, using the World Health Organization (WHO) recommended treatment modality. (sajch.org.za)
To determine baseline clinical characteristics among children with SAM and assess whether HIV infection, disease stage, critical illness at baseline and other comorbidities independently and interactively contributed to excess mortality in this sample. (sajch.org.za)
HIV infection, clinical disease stage, the presence of lower respiratory tract infection, marasmus and disease severity at baseline were all independently associated with excess mortality. (sajch.org.za)

Prognosis for patients with ARDS is generally poor and varies based on the severity of illness, the precipitating insult, and medical comorbidities. (wikidoc.org)
Psychiatric hospitals have limited resources to screen and treat medical comorbidities and are seldom linked to a general medical health service. (sajp.org.za)

The use of severity assessment tools such as the Pneumonia Severity Index (PSI), CURB-65, severe CAP (SCAP), and SMART-COP can facilitate decision-making and guide the antibiotic choice. (bmj.com)

Patients who died from COVID-19 often had comorbidities, such as hypertension, diabetes, and chronic obstructive lung disease. (ox.ac.uk)
MacTel participants were matched based on age, gender and body mass index (BMI) (and where possible hypertension and diabetes) on a 3:1 ratio with controls from the Busselton Health Study. (emmes.com)

The purpose of this study was to estimate its prevalence in family practice patients by counting the number of chronic medical conditions and using a measure that considers the severity of these conditions, the Cumulative Illness Rating Scale (CIRS). (annfammed.org)
A research nurse reviewed medical records and extracted the data regarding chronic illnesses. (annfammed.org)
For each chronic condition, a severity rating was determined in accordance with the CIRS scoring guidelines. (annfammed.org)
Mitrovic and colleagues analyzed the severity of chronic liver disease and its associated comorbidities, the severity of COVID-19 and associated outcomes, as well as patient demographics. (hcplive.com)
This study investigated the impact of comorbidity in 555 patients with chronic lymphocytic leukemia enrolled in two trials of the German Chronic Lymphocytic Leukemia Study Group on first-line treatment with fludarabine plus cyclophosphamide, fludarabine, or chlorambucil. (haematologica.org)
Chronic lymphocytic leukemia was the major cause of death in patients with two or more comorbidities. (haematologica.org)
These results give insight into interactions between comorbidity and therapy of chronic lymphocytic leukemia and suggest that durable control of the hematologic disease is most critical to improve overall outcome of patients with increased comorbidity. (haematologica.org)
To better understand the modes of interaction between comorbidity and CLL therapy, we assessed the comorbidity burden in patients enrolled in the CLL4 and CLL5 trials of the German Chronic Lymphocytic Leukemia Study Group (GCLLSG) 11 , 12 and investigated its impact on treatment outcome in detail. (haematologica.org)
1 Although many patients with recurrent episodes of illness have good symptom remission between episodes, with few residual symptoms, approximately a quarter of patients with major depression have chronic residual depressive symptoms of varying severity with only incomplete remission for many years. (psychiatrictimes.com)
Current nosologies of depressive illnesses do not, however, do a very good job of categorizing chronic depression. (psychiatrictimes.com)
and dysthymic disorder, conceptualized as a more chronic but less severe depressive illness ( Table ). (psychiatrictimes.com)
When the validity of these distinctions is examined, it becomes apparent that this multitude of diagnoses does not reflect the clinical reality of chronic depressive illnesses. (psychiatrictimes.com)

ANAHEIM, CA-Children with a pre-existing illness were at highest risk of severe illness or death due to a COVID-19 infection, but those who were vaccinated had a significantly higher level of protection, according to research presented during the 2022 American Academy of Pediatrics National Conference & Exhibition. (eurekalert.org)
The research found that, across all age groups, presence of pre-existing illness and residence in the Census-defined South region were most often associated with severe outcomes (including hospitalization, ICU admission, use of inpatient respiratory support, and death). (eurekalert.org)
Infants had more severe illness than older children, the author found. (eurekalert.org)
More than a quarter (n = 22 [27.5%]) of patients reported severe pneumonia and/or critical illness. (hcplive.com)
It causes a respiratory illness, and is to severe and fatal cases. (who.int)
ACE2 Expression Is Increased in the Lungs of Patients With Comorbidities Associated With Severe COVID-19. (ox.ac.uk)
Here, we analyzed over 700 lung transcriptome samples from patients with comorbidities associated with severe COVID-19 and found that ACE2 was highly expressed in these patients compared to control individuals. (ox.ac.uk)
This finding suggests that patients with such comorbidities may have higher chances of developing severe COVID-19. (ox.ac.uk)
however, large-scale studies after Paxlovid treatment was dispensed¶ were flagged for investigating severe illness after Paxlovid treatment are limited. (cdc.gov)

Among current comorbidity indices, the Cumulative Illness Rating Scale (CIRS) 11 is one of the best suited to the primary care context. (annfammed.org)
A semi-structured questionnaire on quality of life quality was applied as well as the scale of depressive symptoms Geriatric Depression Scale (GDS) and the index of general health Cumulative Illness Rating Scale (CIRS). (scielo.br)
Um questionário semi- estruturado de qualidade de vida foi aplicado, bem como a escala de sintomas depressivos "Geriatric Depression Scale" (GDS) e o "Índice de Saúde Geral Cumulative Illness Rating Scale" (CIRS). (scielo.br)
By univariate analysis in-hospital clinical adverse events (AEs), a previous hospital admission, number of diagnoses and drugs, comorbidity and severity index (according to Cumulative Illness Rating Scale-CIRS), vascular and liver diseases with a level of impairment at discharge of 3 or more at CIRS were significantly associated with risk of readmission. (unimore.it)

In psychiatric diagnoses it has been argued in part that this "'use of imprecise language may lead to correspondingly imprecise thinking', [and] this usage of the term 'comorbidity' should probably be avoided. (wikipedia.org)
However, in psychiatric classification, comorbidity does not necessarily imply the presence of multiple diseases, but instead can reflect current inability to supply a single diagnosis accounting for all symptoms. (wikipedia.org)
Recently, an expert panel comprised of dermatologists, psychiatrists, and psychologists met to identify three cases that highlight the efficacy and safety of brodalumab in patients with psychiatric comorbidities who failed to respond to other systemic therapies. (jcadonline.com)

In one report from that project, 431 patients with a major depressive episode were monitored for 12 years, assessed every 6 months, and assigned to 1 of 4 symptom levels of depressive illness: major depression, dysthymia, subsyndromal symptoms, or no symptoms. (psychiatrictimes.com)
Severity of gambling is associated with severity of depressive symptoms in pathological gamblers. (ox.ac.uk)
The objective of this study was to investigate the relationship between gambling severity and depressive symptoms in pathological gamblers addicted to slot machines, with the hypothesis that comorbid depressive symptoms are associated with exacerbated gambling symptoms and behavior. (ox.ac.uk)
Conclusion: Participants with a history of mental illness were predisposed to developing negative psychological symptoms as a result of the pandemic. (bvsalud.org)

Sixty-four percent (£4224) of poststroke costs were due to hospitalizations linked to the index stroke, more than 30% of which were given nonvascular primary diagnoses on Hospital Episode Statistics, and £653 (10%) were due to hospitalizations linked to subsequent vascular events. (ox.ac.uk)

Total testosterone, the prevalence of each comorbidity, and the CCI were compared between patients with different grades of ED. Besides, the correlation between total testosterone and the CCI score, the influence of each comorbidity, and the ED severity on the CCI was assessed in a multiple linear regression. (nih.gov)
The purpose of this study was to estimate the prevalence of multimorbidity in family practice patients by counting the number of medical conditions and using a measure that considers their severity. (annfammed.org)
We describe the prevalence of cognitive impairment in a population of community-living older people, its association with functional decline, and degree of comorbidity. (unicatt.it)
[3] There is substantial variance in the rates of ARDS between different countries and geographic regions due to factors such as mean life expectancy , prevalence of different risk factors and comorbidities , and access to healthcare . (wikidoc.org)
The high HIV prevalence rate in the study setting and the resultant treatment outcomes support the notion that the WHO treatment guidelines should be revised to ensure that mechanisms for effective treatment of HIV comorbidity in SAM are in place. (sajch.org.za)
The aim of this cross-sectional study was to evaluate the prevalence of depressed mood among asthma patients ( n = 280) attending a pulmonary clinic in Tehran and compare it with measures of severity of asthma and of health and well-being. (who.int)

International data show conditions including cirrhosis and alcohol-associated liver disease significantly drive the likelihood of critical illness and death in COVID-19 patients. (hcplive.com)
One of the early features of the international response, at least at a clinical level, was to think about the associations between frailty and outcomes from critical illness. (bgs.org.uk)

Our study found that the national disease burden of COVID-19 in children is unequally distributed, with worse outcomes in children with pre-existing illnesses and along racial and geographic lines. (eurekalert.org)
The study shows that infancy, African-American race, Asian race, Hispanic ethnicity, and preexisting illnesses are significantly associated with worse outcomes in children with COVID-19 nationally. (eurekalert.org)
However, inconsistent reporting of severity outcomes in children clouds the impact of COVID-19 on children in the US and child vaccination rates vary widely across states. (eurekalert.org)
65% had comorbidities that were known to influence COVID-19 severity and outcomes. (hcplive.com)

Recurrent MRSA bacteremia was identified by a positive blood culture result from 2 to 180 days after index hospitalization discharge. (cambridge.org)

Most predictive models incorporate age, comorbidity and prior healthcare utilization which may not serve to further risk-stratify an already high-risk population of frail older adults with multi-morbidity. (biomedcentral.com)

In the context of mental health, comorbidity often refers to disorders that are often coexistent with each other, such as depression and anxiety disorders. (wikipedia.org)
The Axis II personality disorders are often criticized because their comorbidity rates are excessively high, approaching 60% in some cases. (wikipedia.org)
Conditional logistic regression was performed as an estimate of the relative risk of stroke in RA patients compared with those with noninflammatory rheumatic disorders, and to examine severity and anti-tumor necrosis factor (anti-TNF) treatment effects in RA. (nih.gov)
Mood disorders are among the most prevalent forms of mental illness. (psychiatrictimes.com)

Risk factors for recurrent MRSA bacteremia included comorbidities, severity of illness, duration of bacteremia, and receipt of only vancomycin. (cambridge.org)

In psychiatry, psychology, and mental health counseling, comorbidity refers to the presence of more than one diagnosis occurring in an individual at the same time. (wikipedia.org)
Prior to the development of the Berlin Definition in 2012, a greater emphasis was placed on excluding other potential illnesses prior to making a diagnosis of ARDS. (wikidoc.org)

A majority of patients (61.2%) reported body mass index (BMI) in the range of 18.5 - 24.9 kg/m 2 . (hcplive.com)
Any comorbidity was present in 194 (52%) patients, with a Charlson Index of 1 point (0 to 2). (biomedcentral.com)
The BI was calculated for 318 patients who were discharged from hospital: ICU admission index 80 (70 to 100) and discharge 100 (80 to 100). (biomedcentral.com)
Disease control in patients with two or more comorbidities was better with fludarabine plus cyclophosphamide than with fludarabine treatment, but not with fludarabine compared to chlorambucil treatment. (haematologica.org)
However, many CLL patients in routine practice are elderly and suffer from comorbidities. (haematologica.org)
Recently, comorbidity was identified as an adverse prognostic factor in patients with untreated or treated CLL. (haematologica.org)
Our systems biology approach offers a possible explanation for increased COVID-19 severity in patients with certain comorbidities. (ox.ac.uk)
MacTel patients did not have a higher risk of sleep apnoea when compared to age, sex and BMI -matched controls (mean ± SD Apnoea hypopnea index [AHI] cases 9.6 ± 14.7 vs. controls 9.7 ± 10.8, P = 0.95). (emmes.com)
Patients with TIA incurred nonsignificantly higher costs due to hospitalizations linked to subsequent vascular events (£774) than for hospitalizations linked to the index TIA (£720). (ox.ac.uk)
The vast majority of patients with ARDS are managed in an intensive care unit (ICU) , where many will require mechanical ventilation at some point during the course of their illness and recovery. (wikidoc.org)
In unadjusted analyses, patients with low health literacy were less likely to believe they will always have COPD (p = 0.003, Cohen's d = 0.42), and were more likely to be concerned about their illness ((p = 0.04, Cohen's d = 0.17). (plos.org)
Patient selection Subject selection often is limited by censoring the severity distribution through entry criteria where exclusions often require elimination of patients who are suicidal or psychotic, or have a variety of common comorbidities, such as physical illness, substance abuse, or personality disorder. (anti-cancers.com)

Limited national data were available 18 years of age or older, either a fam- are, however, frequently associated on the characteristics of caregivers and ily member or a voluntary worker, who with illnesses that cause disability and their burden. (who.int)

Currently there is no know treatment however with similar comorbidities to Obstructive Sleep Apnoea (OSA) there is plausibility of an association which may accelerate disease progression. (emmes.com)

This may be due to heterogeneity in the aetiology of exacerbations, delay between onset and presentation of the exacerbation for sampling of the biomarker, or shifts in the baseline (stable) levels with age or disease severity. (bmj.com)
No markers of disease progression in the cases were associated with any marker of OSA severity. (emmes.com)
The final dataset will include self-reported data on demographic characteristics, disease-severity, self-management behaviors, cognition, and health literacy, as well as medication and disease data obtained from electronic records abstractions. (plos.org)
Psoriasis disease severity was measured using the Psoriasis Area and Severity Index (PASI) score. (jcadonline.com)
BACKGROUND: Diarrhoeal disease is a leading cause of childhood illness and death globally, and Shigella is a major aetiological contributor for which a vaccine might soon be available. (cdc.gov)

Comorbidity is often referred to as multimorbidity even though the two are considered distinct clinical scenarios. (wikipedia.org)
A delay in determining the severity of the illness and where best to treat the patient can have an impact on clinical outcome and costs. (bmj.com)

assert this indicates these categories of mental illness are too imprecisely distinguished to be usefully valid for diagnostic purposes, impacting treatment and resource allocation. (wikipedia.org)

Stroke is predicted by RA severity, certain cardiovascular risk factors, and comorbidity. (nih.gov)

Longer duration of index bacteremia, increased severity of illness, receipt of only vancomycin, community-acquired infection, and several comorbidities were risk factors for recurrence. (cambridge.org)

The CCI is significantly associated with the ED severity, but it shows a weak correlation with the testosterone levels. (nih.gov)

In this cohort of urban individuals with COPD, low health literacy was prevalent, and associated with illness beliefs that predict decreased adherence. (plos.org)

After adjustment for other prognostic factors and treatment, comorbidity maintained its independent prognostic value in a multivariate Cox regression analysis. (haematologica.org)

Using the framework of the Self-Regulation Model, illness and medication beliefs were measured with the Brief Illness Perception Questionnaire (B-IPQ) and Beliefs about Medications Questionnaire (BMQ). (plos.org)
The commonly used mental health assessment tools were the Patient Health Questionnaire (41.7%), Generalized Anxiety Disorder Scale (36%), 21-item Depression, Anxiety, and Stress (13.9%), Impact of Event Scale (12.5%), Pittsburgh Sleep Quality Index (9.7%), Symptom Checklist and the General Health Questionnaire (6.9% each). (bvsalud.org)
Une étude transversale, reposant sur un questionnaire, a été conduite en recourant à un échantillonnage non probabiliste par choix raisonné. (who.int)

His Status epilepticus study incorporates themes from Stroke, Encephalopathy, Pediatrics and Comorbidity. (research.com)

Life-threatening ventricular arrhythmias, unstable angina (characterized by increasingly frequent episodes with modest exertion or at rest, worsening severity, and prolonged duration), and/or myocardial infarction within four weeks before screening. (who.int)

Is There a Relationship Between Obesity and Respiratory Illnesses in Adults? (medscape.com)

Acute respiratory distress syndrome ( ARDS ), originally known as adult respiratory distress syndrome (to contrast with neonatal respiratory distress syndrome ) is a serious and potentially life-threatening inflammatory lung condition that develops rapidly (usually within 24 to 48 hours) in the setting of sepsis , toxic exposures , adverse drug reactions , trauma , or other critical illnesses. (wikidoc.org)
The various areas that Nathan B. Fountain examines in his Adverse effect study include Young adult, Severity of illness, Quality of life and Mood. (research.com)

Acute severity of illness was calculated (SAPS II and SOFA scores) on day 1 of admission. (biomedcentral.com)

Comorbidity describes the effect of all other conditions an individual patient might have other than the primary condition of interest, and can be physiological or psychological. (wikipedia.org)

The current strategy is to implement an individualized approach taking into consideration the patient underlying comorbidities, reason for mechanical ventilation (MV), and potential complications of the procedure. (hindawi.com)

Frailty assessment and scaling allows a more nuanced and evidence-based assessment of an individual's baseline, which should inform what it is likely to be possible to achieve in the face of an illness, but such plans should always be accompanied by discussion - a shared decision making process. (bgs.org.uk)

Linked hospital and mental health service data were used to assess in-hospital death, repeat self-harm and mental health service use in the 12 months following index self-harm hospital admission. (deepdyve.com)

COVID-19 during the 5-15 days after Paxlovid treatment was inhibitor that blocks replication of SARS-CoV-2 (the virus that dispensed for mild to moderate COVID-19 illness were rarely causes COVID-19) and has been shown to reduce the risk for identified. (cdc.gov)

Anatomy1

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Analytical, Diagnostic and Therapeutic Techniques and Equipment79

Psychiatry and Psychology60

Phenomena and Processes17

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