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Submandibular Gland NeoplasmsSubmandibular GlandSalivary GlandsSalivary Gland NeoplasmsSubmandibular Gland DiseasesSebaceous Gland NeoplasmsAnal Gland NeoplasmsAdenoma, PleomorphicSalivary Glands, MinorSalivary Gland DiseasesSublingual GlandSalivary DuctsParotid GlandParotid NeoplasmsSublingual Gland NeoplasmsCarcinoma, MucoepidermoidSialadenitisPerianal GlandsSalivary Gland CalculiSalivationCarcinoma, Adenoid CysticSalivary Proteins and PeptidesPalatal NeoplasmsAdenolymphomaSalivaAquaporin 5MyoepitheliomaChloropreneExocrine GlandsSjogren's SyndromeMammary Glands, AnimalParasympathetic Nervous SystemIncidenceXerostomiaSialographyLingual NerveLacrimal ApparatusSweat Gland NeoplasmsImmunohistochemistrySialorrheaKallikreinsEndocrine Gland NeoplasmsSweat GlandsSodium Pertechnetate Tc 99mSebaceous GlandsSalivary CystatinsProline-Rich Protein DomainsParasympathectomyHarderian GlandDihydroergotamineAdrenal GlandsPilocarpine
Minor salivary glandTumorsMalignant neoplasmCarcinomaSublingual glandsExcisionPolymorphous AdenocarcinomaLiver NeoplasmsCarcinomasParotid glandsTumorBenignAriseDuctSubtypeEtiologyHigher incidencePleomorphicOralSerousSialolithiasis100,000SialadenitisMalignanciesCongenitalCommonlyPrognosisMucosaTissueRarelySaliva producedPatientsLesionsHead and neckMucinDiseasesDisordersRareHumansUncommonMajorNeckVascularClinicalFlowReportUpper
Minor salivary gland5
  • Almost half of all submandibular gland neoplasms and most sublingual and minor salivary gland tumors are malignant. (medscape.com)
  • Necrotizing sialometaplasia is a lesion that usually arises from a minor salivary gland on the palate. (wikipedia.org)
  • they are usually associated with the sublingual gland, and less often they arise from the submandibular gland or a minor salivary gland. (wikipedia.org)
  • Clinically, a patient with minor salivary gland sialolithiasis usually presents with a palpable, firm, submucosal nodule. (bvsalud.org)
  • The aim of this study was to report three rare cases of minor salivary gland sialolithiasis, which were treated surgically. (bvsalud.org)
Tumors19
  • Although researchers have learned much from the study of this diverse group of tumors over the years, the diagnosis and treatment of salivary gland neoplasms remain complex and challenging problems for the head and neck surgeon. (medscape.com)
  • Salivary gland neoplasms make up 6% of all head and neck tumors. (medscape.com)
  • In children and adolescents, salivary gland tumors make up 0.5% of all malignancies. (medscape.com)
  • [ 4 , 5 ] ) Benign neoplasms occur more frequently in women than in men, but malignant tumors are distributed equally between the sexes. (medscape.com)
  • The relative proportion of submandibular tumors is shown in the table below. (medscape.com)
  • Most tumors (65%) are benign, with hemangiomas being the most common, followed by pleomorphic adenomas. (medscape.com)
  • Successful diagnosis and treatment of patients with salivary gland tumors require a thorough understanding of tumor etiology, biologic behavior of each tumor type, and salivary gland anatomy. (medscape.com)
  • An estimated 700 deaths (0.4 per 100,000 for males and 0.2 per 100,000 for females) related to salivary gland tumors occur annually. (medscape.com)
  • The relative proportion of submandibular tumors is shown in the image below. (medscape.com)
  • This theory more logically explains neoplasms that contain multiple discrete cell types, such as pleomorphic adenomas and Warthin tumors. (medscape.com)
  • Aim: The aim of this study is to investigate the DNA ploidy and S-Phase Fraction (SPF) of some Salivary Gland Tumors (SGTs) in Egyptian patients and to investigate the correlation between these two biological parameters and the presumptive behavior of these neoplasms. (researchgate.net)
  • These tumors develop within the mucosa that lines the upper aerodigestive tract (squamous-cell carcinomas) or the different glands in this region (adenocarcinomas). (biomedcentral.com)
  • ABSTRACT BACKGROUND: Neuroendocrine tumors are rare neoplasms of uncertain biological behavior. (bvsalud.org)
  • Salivary gland tumors are rare tumors that account for 3 to 4% of head and neck neoplasms. (waocp.com)
  • These tumors may arise from 6 major and numerous minor salivary glands. (waocp.com)
  • This study was designed to investigate the factors affecting the prognosis of salivary gland tumors. (waocp.com)
  • This study is a retrospective descriptive study in which the records of patients with salivary gland tumors referred to the Radiotherapy and Oncology Center of Namazi Hospital from 2005 to 2015 were reviewed. (waocp.com)
  • Salivary gland tumors are diverse and rare tumors and consists both benign and malignant lesions [1, 2]. (waocp.com)
  • These tumors are more common in adulthood and older ages and about 5% of cases occur under 16 years of age (8-10). (waocp.com)
Malignant neoplasm3
  • Extranodal natural killer/T-cell lymphoma (ENKL) is an aggressive and infrequent malignant neoplasm. (bvsalud.org)
  • Salivary gland type malignant neoplasm arising from bronchial seromucinous glands. (cancerhealthcenter.com)
  • A primary malignant neoplasm of epithelial liver cells. (lookformedical.com)
Carcinoma9
  • Mucoepidermoid carcinoma is the most common salivary gland malignancy in children. (medscape.com)
  • Tobacco and alcohol, which are highly associated with head and neck squamous cell carcinoma, have not been shown to play a role in the development of malignancies of the salivary glands. (medscape.com)
  • Sebaceous carcinoma is a very rare, aggressive, malignant tumor arising in the adnexal epithelium of the sebaceous gland. (biomedcentral.com)
  • The clinical differential diagnosis included squamous cell carcinoma, basal cell carcinoma with sebaceous differentiation, and salivary gland neoplasms. (biomedcentral.com)
  • Sebaceous carcinoma (SC) is a rare neoplasm. (biomedcentral.com)
  • It seems that these intraoral sebaceous glands can rarely give rise to a variety of sebaceous neoplasms, such as sebaceous carcinoma [ 7 ]. (biomedcentral.com)
  • Adenoid Cystic Carcinoma was the most common histological type (30.57%) and Adenocarcinoma with a prevalence of 1.91% had the lowest prevalence rate in this study. (waocp.com)
  • The prevalence of salivary gland carcinoma has increased [3]. (waocp.com)
  • Other types in order of prevalence were MUC, SCC, carcinoma ex-pleomorphic, acinic cell carcinoma, salivary duct carcinoma, polymorphous low grade adenocarcinoma and adenocarcinoma (Table1). (waocp.com)
Sublingual glands3
Excision2
  • if it is larger and causing symptoms, excision of the sublingual gland may be indicated. (wikipedia.org)
  • The aim of this case series was to show our experience gained in two clinical cases of submandibular gland excision through an extraoral approach, using the submandibular access technique. (bvsalud.org)
Polymorphous Adenocarcinoma1
  • Salivary Gland Polymorphous Adenocarcinoma: Clinicopathological Features and Gene Alterations in 36 Japanese Patients. (nagoya-u.ac.jp)
Liver Neoplasms1
Carcinomas2
  • After therapy, the incidence of pleomorphic adenomas, mucoepidermoid carcinomas, and squamous cell carcinomas is increased. (medscape.com)
  • While several reports document sebaceous adenomas arising from sebaceous glands of the oral cavity, oral sebaceous carcinomas are extremely rare. (biomedcentral.com)
Parotid glands3
  • Among salivary gland neoplasms, 80% arise in the parotid glands, 10-15% arise in the submandibular glands, and the remainder arise in the sublingual and minor salivary glands. (medscape.com)
  • Those located in the minor salivary glands had a lower recurrence risk than did pleomorphic adenomas in the parotid glands. (medscape.com)
  • The parotid glands are in front of the ears, one on side, and secrete mostly serous saliva, via the parotid ducts (Stenson ducts), into the mouth, usually opening roughly opposite the second upper molars. (wikipedia.org)
Tumor6
  • That is, as the size of the gland decreases, the incidence of malignancy of a tumor in the gland increases in approximately these proportions. (medscape.com)
  • The most common tumor of the parotid gland is the pleomorphic adenoma , which represents about 60% of all parotid neoplasms, as seen in the table below. (medscape.com)
  • In the multicellular theory, each tumor type is associated with a specific differentiated cell of origin within the salivary gland unit. (medscape.com)
  • The most common primary tumor site was in the gastrointestinal tract in 64% of cases. (bvsalud.org)
  • Demographic and Pathologic Characteristics of the 157 Patients with Salivary Gland Tumor. (waocp.com)
  • It ranges from a well-differentiated tumor with EPITHELIAL CELLS indistinguishable from normal HEPATOCYTES to a poorly differentiated neoplasm. (lookformedical.com)
Benign5
  • Neoplasms that arise in the salivary glands are relatively rare, yet they represent a wide variety of both benign and malignant histologic subtypes as seen in the image below. (medscape.com)
  • Most series report that about 80% of parotid neoplasms are benign, with the relative proportion of malignancy increasing in the smaller glands. (medscape.com)
  • This study on 279 tumours of the salivary glands was conducted to analyse whether the assessment of DNA ploidy by flow cytometry may assist histopathology in discriminating benign from malignant types of tumours. (researchgate.net)
  • In the histological classification of salivary gland cancers by WHO in 2005, there were 10 subtypes in the benign group and 24 subtypes in the malignant group, and benign subtypes are 5 to 7 times more common than malignant types and most of them (more than 80%) are PA (pleomorphic adenoma) [4]. (waocp.com)
  • Malignant neoplasms show a greater degree of anaplasia and have the properties of invasion and metastasis, compared to benign neoplasms. (lookformedical.com)
Arise1
  • Generally, the lesions arise in the meibomian glands of the eyelid. (biomedcentral.com)
Duct3
  • The submandibular gland is medial to the angle of the mandible, and it drains its mixture of serous and mucous saliva via the submandibular duct (Wharton duct) into the mouth, usually opening in a punctum in the floor of mouth. (wikipedia.org)
  • Oral mucoceles are common, and are caused by rupture of a salivary gland duct and spillage of mucin into the surrounding tissues. (wikipedia.org)
  • This could be explained by the anatomy of Wharton's duct, and the chemical composition of the saliva produced by this gland. (bvsalud.org)
Subtype1
  • Mantle cell lymphoma (MCL) is a rare subtype of B-cell neoplasm and it accounts for about 3~6% of all non-Hodgkin's lymphomas. (kjhno.org)
Etiology2
Higher incidence1
  • Introduction: Oligohydramnios is associated with fetal complications and a higher incidence of maternal operative morbidity. (who.int)
Pleomorphic1
  • A study from the Netherlands, by Valstar et al, found an overall 20-year recurrence rate for salivary gland pleomorphic adenomas of 6.7%, with the first recurrence arising at a median of 7 years. (medscape.com)
Oral2
  • Although the oral cavity and upper lip are the most common sites, they can develop in any region of the oral cavity that contains minor salivary glands. (bvsalud.org)
  • Although the upper lip and the buccal mucosa are the most frequently affected sites, they may develop in any part of the oral cavity that contains minor salivary glands 1-5 . (bvsalud.org)
Serous1
  • Analysis of the soft tissues and mandible within the radiation field revealed severe unilateral alopecia and dermatitis of the skin, extensive inflammation of the submandibular gland with loss of serous secretory cells, hyperkeratinization and dense connective fiber bundles of the gingival tissue, and disturbed tooth development with necrosis of the pulp. (biomedcentral.com)
Sialolithiasis5
  • Sialolithiasis is the most common cause of sialadenitis in the submandibular gland, in which the highest incidence of this condition occurs, among the major salivary glands. (bvsalud.org)
  • There are several alternatives and techniques for the treatment of sialolithiasis, including lithotripsy, sialoendoscopy, and conservative removal of the sialoliths or complete removal of the submandibular gland, through the transoral and extraoral routes for access to the gland. (bvsalud.org)
  • Sialolithiasis, or salivary calculus, is a disease of the salivary glands, characterized by the formation of mineralized structures within the excretory salivary ducts or the glandular parenchyma. (bvsalud.org)
  • Although rare, sialolithiasis can also occur in the minor salivary glands. (bvsalud.org)
  • This study presents three cases of sialolithiasis of minor salivary glands of the upper and lower lip, addresses their clinical characteristics and correlation with microscopic findings, diagnosis and treatment plans. (bvsalud.org)
100,0002
Sialadenitis2
  • Sialadenitis is inflammation of a salivary gland, usually caused by infections, although there are other, less common causes of inflammation, such as irradiation, allergic reactions, and trauma. (wikipedia.org)
  • Mumps is the most common viral sialadenitis. (wikipedia.org)
Malignancies1
  • Regardless of the localization, sebaceous malignancies must be considered aggressive neoplasms with potential for regional and distant metastases. (biomedcentral.com)
Congenital1
Commonly3
Prognosis1
  • Treatment is based on surgical removal of both the sialolith and the gland involved, with a good prognosis 2-4 . (bvsalud.org)
Mucosa2
Tissue3
  • They include: Aplasia Atresia Ectopic salivary gland tissue Stafne defect - an uncommon condition which some consider to be an anatomic variant rather than a true disease. (wikipedia.org)
  • It is thought to be created by an ectopic portion of salivary gland tissue which causes the bone of the mandible to remodel around the tissue, creating an apparent cyst like radiolucent area on radiographs. (wikipedia.org)
  • Abnormal growths of tissue that follow a previous neoplasm but are not metastases of the latter. (lookformedical.com)
Rarely1
Saliva produced1
  • Salivary gland dysfunction affects the flow, amount, or quality of saliva produced. (wikipedia.org)
Patients3
  • Contrasting information was derived through a literature review by Louredo et al, which indicated that in pediatric patients, most salivary gland neoplasms (75.4%) are malignant. (medscape.com)
  • Salivary gland neoplasms occurred with slightly greater frequency in girls (57.4% of patients) than in boys. (medscape.com)
  • The liver is one of the most common sites of metastases, occurring in 50% of patients with metastatic disease. (bvsalud.org)
Lesions2
  • The most obvious value of DNA flow cytometry in salivary gland tumours is thus its contribution to assist histopathology in identifying potentially malignant lesions. (researchgate.net)
  • A combination of clinical, radiographic and histological examinations is fundamental for diagnosis, due to the possibility of overlapping clinical characteristics common to other lesions. (bvsalud.org)
Head and neck2
  • Head and neck cancer (HNC) is a heterogeneous group of neoplasms that share a common anatomic origin. (biomedcentral.com)
  • They account for 3 to 4% of head and neck neoplasms. (waocp.com)
Mucin1
  • Neoplasms containing cyst-like formations or producing mucin or serum. (lookformedical.com)
Diseases1
  • Salivary gland diseases (SGDs) are multiple and varied in cause. (wikipedia.org)
Disorders3
  • Some disorders affecting the salivary glands are listed below. (wikipedia.org)
  • It is one of the most common neurologic disorders of the cranial nerves (see the image below). (medscape.com)
  • Bell palsy is one of the most common neurologic disorders affecting the cranial nerves, and it is the most common cause of facial paralysis worldwide. (medscape.com)
Rare2
Humans1
Uncommon1
Major1
Neck1
  • C, D) The enhanced neck CT scans show 2.2×1.4cm homogenous enhanced well-margined round mass on mid-portion of left parotid gland (arrows). (kjhno.org)
Vascular1
  • It is thought to be due to vascular infarction of the salivary gland lobules. (wikipedia.org)
Clinical1
Flow1
Report1
  • Nassehi Y, Rashid A, Pitiyage G, Jayaram R. Floor of mouth schwannoma mimicking a salivary gland neoplasm: a report of the case and review of the literature. (ucacue.edu.ec)
Upper1