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  • toxicity
  • Organ toxicity in cancer therapy is likely caused by an underlying disposition for given pathophysiological mechanisms in the individual patient. (mdpi.com)
  • To determine the safety and toxicity of high-dose systemic methotrexate (MTX) and dexamethasone (DEX) combined with zidovudine (AZT) and brain irradiation in patients with AIDS-related primary central nervous system (CNS) lymphoma and to determine response rates and survival of treated patients. (clinicaltrials.gov)
  • Biological
  • In view of the complexity of biological responses to cancer therapy, this communication reports on a "top-down" strategy, starting with the systematic assessment of adverse effects within a defined therapeutic context and proceeding to transcriptomic and proteomic analysis of relevant patient tissue samples and computational exploration of the resulting data, with the ultimate aim of utilizing information from functional connectivity networks in evaluation of patient safety in multimodal cancer therapy. (mdpi.com)
  • This download combined modality will Understand how biological acquisition is screened our of engaging life-long street and company Repeatability. (sierrasignsaz.com)
  • entities
  • The most successful targeted therapies are chemical entities that target or preferentially target a protein or enzyme that carries a mutation or other genetic alteration that is specific to cancer cells and not found in normal host tissue. (wikipedia.org)
  • clinical
  • citation needed] His scientific career in neuro- and thoracic oncology started in 1988 and was marked by a zealous focus on evidence-based medicine through clinical and translational research, including a variety of areas such as endobronchial brachytherapy, radioimmunotherapy, stereotactic radiosurgery, fractionated stereotactic radiotherapy, image-guided and intensity-modulated radiotherapy, radioprotectors, radiosensitizers, altered fractionation, combination chemoradiotherapy as well as combining targeted agents with radiotherapy. (wikipedia.org)
  • In regard to investigation of causes and potential targets for therapy, the route used starts with data obtained from clinical observations, enters basic research, and, once convincing and independently confirmed results are obtained, proceeds with clinical research, involving appropriately designed trials on consenting human subjects, with the aim to test safety and efficiency of the therapeutic intervention method. (wikipedia.org)
  • Madolyn M. Liebing, Ph.D. (of Aspen Achievement then, and currently of Journey Wilderness) was the first clinical psychologist to integrate clinical therapy with wilderness programming. (wikipedia.org)
  • Additionally, most wilderness therapy programs have highly trained clinical staff either on the expedition or in active and ongoing consultation with the team. (wikipedia.org)
  • tumor cells
  • The definitive experiments that showed that targeted therapy would reverse the malignant phenotype of tumor cells involved treating Her2/neu transformed cells with monoclonal antibodies in vitro and in vivo by Mark Greene's laboratory and reported from 1985. (wikipedia.org)
  • patients
  • Since the underlying immunodeficiency state is not affected by therapy directed against the lymphoma, patients are still prone to life-threatening opportunistic infections or relapse of lymphomatous disease within the CNS. (clinicaltrials.gov)
  • Biomarkers are usually required to aid the selection of patients who will likely respond to a given targeted therapy. (wikipedia.org)
  • By exposing patients to interpersonal problems, therapy and group activities in an unfamiliar context away from home, wilderness therapy encourages the development of healthy self-esteem and social skills. (wikipedia.org)
  • In many patients with cancer, this condition does not develop until months or even years after therapy has concluded. (wikipedia.org)
  • Death is attributable to upper airway obstruction and suffocation in half of patients, and to a combination of complications of local and distant disease, or therapy, or both in the remainder. (wikipedia.org)
  • medical
  • medical citation needed] Alternately, some programs are derived from a more ecopsychological perspective, according to the director of the wilderness therapy program at Naropa University, "through contemplative practice and the experiential outdoor classroom, students gain further self-awareness and the ability to respond to whatever arises in the moment. (wikipedia.org)
  • Methods
  • Although the therapy is often used for behavior modification by the families of young people, the aims and methods of wilderness therapy do not center on behavior modification. (wikipedia.org)
  • major
  • One of the major differences between boot camps and wilderness therapy is the underlying philosophical assumptions (wilderness therapy being driven by the philosophy of experiential education and theories of psychology and boot camps being informed by a military model). (wikipedia.org)
  • development
  • citation needed] The New York Asylum and the San Francisco Agnew Asylum played an early role in the development of wilderness therapy, drawing upon the philosophies of Kurt Hahn. (wikipedia.org)
  • cells
  • This study examines whether this combination therapy can reduce the number of HIV-infected cells hidden in the lymph nodes and blood. (clinicaltrials.gov)
  • Type
  • His report on Radium Therapy in Cancer, at the Memorial Hospital (1915-1916), which appeared in book form in 1917 was the most comprehensive work of its type published in the United States. (wikipedia.org)
  • various
  • It was Mercieca's recovery and discoveries that led her to become trained in various skills, acquiring a Life and Business certificate in Coaching, before going on to learn the art of Neuro-Linguistic Programming, Time-Line Therapy, Hypnosis and Wholebrain Intelligence (she is also accredited with the relevant boards in America). (wikipedia.org)
  • programs
  • The success of the Outward Bound outdoor education program in the 1940s inspired the approach taken by many current-day wilderness therapy programs, though some adopted a survivalist methodology. (wikipedia.org)
  • Many wilderness therapy programs avoid what they view as manipulations, contrived activities, psychological games, and contrived consequences. (wikipedia.org)
  • Some programs which advertise as "wilderness therapy" are actually boot camps in a wilderness environment. (wikipedia.org)
  • These can sometimes be distinguished from other wilderness therapy by such programs promising behavior modification for troubled teens, but it is hard to tell just from the ads. (wikipedia.org)
  • cognitive behavio
  • Success in treating anxiety with cognitive behavioral therapy (CBT) interventions developed by Meichebaum inspired Novaco to modify the stress inoculation training to be suitable for anger management. (wikipedia.org)
  • Audio therapy synthesises elements from a number of discreet areas of research and practice, including receptive music therapy, bibliotherapy, creative visualization, guided imagery, guided meditation, sound healing, and cognitive behavioral therapy. (wikipedia.org)
  • One such discipline is cognitive behavioral therapy. (wikipedia.org)
  • prostate
  • Pfizer Inc. ( PFE ) and Astellas Pharma Inc. (TSE: 4503, President and CEO: Yoshihiko Hatanaka, "Astellas") announced today that the Phase 3 PROSPER trial evaluating XTANDI ® (enzalutamide) plus androgen deprivation therapy (ADT) versus ADT alone in patients with non-metastatic (M0) Castration-Resistant Prostate Cancer (CRPC) met its primary endpoint of improved metastasis-free survival (MFS). (yahoo.com)
  • PROSPER enrolled patients with prostate cancer that had progressed, based on a rising prostate-specific antigen (PSA) level despite androgen deprivation therapy (ADT), but who had no symptoms with no prior or present evidence of metastatic disease. (yahoo.com)
  • injuries
  • Physical therapy attempts to address the illnesses, or injuries that limit a person's abilities to move and perform functional activities in their daily lives. (wikipedia.org)
  • focuses
  • The third mode of therapy used is skills generalization, which focuses on helping clients integrate the skills taught in DBT into real-life situations. (wikipedia.org)
  • provide
  • Ice can be combined with a wrapping to minimize swelling and provide support. (wikipedia.org)
  • Thirdly, whilst receptive music therapy may provide live as well as recorded music, to which the patient or participant listens, audio therapy is always provided via a sound recording. (wikipedia.org)
  • physical therapy
  • Physical therapy is a very important part of rehabilitation after a shoulder fracture. (givensportspt.com)
  • The goal of physical therapy is to return you to normal activities after the normal course of bone healing. (givensportspt.com)
  • After the development of orthopedics in the eighteenth century, machines like the Gymnasticon were developed to treat gout and similar diseases by systematic exercise of the joints, similar to later developments in physical therapy. (wikipedia.org)
  • The earliest documented origins of actual physical therapy as a professional group date back to Per Henrik Ling, "Father of Swedish Gymnastics," who founded the Royal Central Institute of Gymnastics (RCIG) in 1813 for manipulation, and exercise. (wikipedia.org)
  • Modern physical therapy was established towards the end of the 19th century due to events that had an effect on a global scale, which called for rapid advances in physical therapy. (wikipedia.org)
  • Content
  • Firstly, whilst receptive music therapy provides musical sound, to which the patient or participant listens, audio therapy also uses other kinds of acoustic content, including the spoken word and ambient noise. (wikipedia.org)
  • mental
  • Physical support often includes medical detox and subsequent medical support (including medication), and mental support includes in-depth therapy to address the underlying causes of addiction. (rehab.com)
  • Whether provided in person, or delivered via media, as it is in audio therapy the verbal instruction consists of words, often pre-scripted, intended to direct the participant's attention to intentionally generated visual mental images that precipitate a positive psychologic and physiologic response, incorporating increased mental and physical relaxation and decreased mental and physical stress. (wikipedia.org)
  • field
  • Neuroimmunology is a field combining neuroscience, the study of the nervous system, and immunology, the study of the immune system. (wikipedia.org)
  • effect
  • Our subsequent experimental work focused upon practical applications of BOEC: their use for gene therapy, tissue engineering, assessment of mutant gene effect, and discovery of heterogeneity in endothelial biology. (jci.org)
  • repair
  • This manuscript reviews the role of the ECM in cardiac repair and remodeling and discusses matrix-based therapies that may attenuate remodeling while promoting repair and regeneration. (jci.org)
  • means
  • This means that by using a light therapy device, you can get rid of your braces much sooner and get back to enjoying food and life. (redlightman.com)