• Bacterial biofilms play an important role in UTIs, responsible for persistent infections leading to recurrences and relapses. (mdpi.com)
  • Engineer microbial biofilms that physically modify surfaces to decrease bacterial attachment sites and prevent bacterial adhesion. (ebrc.org)
  • Engineer microbial biofilms that degrade bacterial holdfast structures to prevent "primary surface colonizers" from attaching and starting the biofilm formation process. (ebrc.org)
  • Microscopic evaluation of these biofilms indicated that streptococcus accounts for approximately 80 percent of this colonization. (news-medical.net)
  • Soon after establishing multilayered biofilms streptococci establish adhesions on their surfaces. (news-medical.net)
  • Many enteric pathogens are equipped with multiple cell adhesion factors which are important for host tissue colonization and virulence. (uni-muenchen.de)
  • A new class of phenolic phytoalexins with antimicrobial activities against bacterial and fungal pathogens in rice comprises stress-induced phenylamides, which rely on the shikimate pathway for aromatic L-amino acids and the phenylpropanoid pathway for the phenolic acid moieties in phenylamides and sakuranetin [ 6 ]. (researchsquare.com)
  • Persistent surveillance and characterization of enteric ETEC isolates are vital for tracking the community presence of MDR bacterial species in order to recommend effective treatment strategies and help mitigate the spread of resistant pathogens. (biomedcentral.com)
  • It is imperative that both archived and current bacterial isolates from underdeveloped regions undergo extensive MDR characterization to inform national strategies designed to halt the continuing spread of these dangerous pathogens. (biomedcentral.com)
  • Dental plaque biofilm may promote oral and oropharyngeal colonization of respiratory pathogens in hospitalized subjects. (who.int)
  • Microbial Surface Colonization and Biofilm Development in Marine Environments. (ebrc.org)
  • The present study investigated the anti-adhesive and anti-biofilm activity of a saline extract of blueberry (Vaccinium corymbosum) targeting intestinal colonization by a highly adherent Klebsiella pneumoniae strain. (blueberry.org)
  • Pantoea stewartii is a species of plant pathogenic bacteria that causes Stewart's wilt of corn, as well as jackfruit-bronzing disease, bacterial leaf wilt of sugarcane, and leaf blight in rice. (wikipedia.org)
  • Due to the resistance of some bacteria to antibiotics, research in the field of dealing with bacterial infections is necessary. (nature.com)
  • Furthermore, the anti-adhesive activity was still expressed when substituted dextrans were preincubated with fibronectin-coated PMMA but washed away at the time when radiolabeled bacteria were added to the adhesion assay. (unige.ch)
  • Kawai K, Urano M, Ebisu S. Effect of surface roughness of porcelain on adhesion of bacteria and their synthesizing glucans. (unicamp.br)
  • It is important to develop functional transmucosal implant surfaces that reduce the number of initially adhering bacteria and they need to be modified to improve the anti-bacterial performance. (hindawi.com)
  • The first method is to inhibit the initial adhesion of oral bacteria. (hindawi.com)
  • The second method is to inhibit the colonization of the oral bacteria, which involves surface antibacterial activity [ 7 ]. (hindawi.com)
  • Moreover, although the abundance of most protein groups reflected that of related bacterial populations, we found a specific independent regulation of bacteria-derived cell envelope proteins. (bmj.com)
  • Adhesive pili are essential for colonization, biofilm formation, virulence and pathogenesis of many environmental and pathogenic bacteria. (dentalreach.today)
  • Recent studies concluded that macro-pores allowed for bacteria to become entrapped, causing bacterial colonization resulting in graft failure. (bonegrafting.com)
  • Like many bacteria, Enterococcus faecalis encodes a number of adhesins involved in colonization or infection of different niches. (nih.gov)
  • IMPORTANCE Most bacteria express multiple adhesins that contribute to surface attachment and colonization. (nih.gov)
  • Serine‐rich repeat (SRR) glycoproteins are a family of adhesins that fulfil an important role in adhesion. (helmholtz-hzi.de)
  • However, the network and relationships between the various adhesins of a single bacterial species are less well understood. (nih.gov)
  • Here, we examined two well-characterized adhesins in Enterococcus faecalis , aggregation substance and endocarditis- and biofilm-associated pili, and found that they exhibit distinct functional contributions depending on the growth stage of the bacterial community. (nih.gov)
  • Genes encoded in LAA contribute to the adhesion phenotype though the expression of STEC adhesins is a coordinated event that depends not only the strain but also on the environment as well as its genetic background. (biomedcentral.com)
  • Unusual and multiresistant bacterial infections are increasingly reported in cystic fi bro- sis (CF) patients ( 1 ). (cdc.gov)
  • Bacterial infections pose a significant threat to human health and cause various diseases. (nature.com)
  • Over the years, antibiotics have played a crucial role in combating bacterial infections by benefiting from technological advancements and medical knowledge 13 . (nature.com)
  • Mucinases and sialidases contribute to the process of invasion and colonisation in many conditions and infections of the female reproductive tract by degrading the protective cervical mucus. (bmj.com)
  • Recent evidence suggests that mucinases in particular may play a vital part in the aetiology of certain conditions and/or infections of the female genital tract, and may also be involved in adverse sequelae resulting from microbial colonisation. (bmj.com)
  • Understanding these oral floras can help in assessing various dental diseases like gingivitis and periodontitis which account for the most frequent bacterial infections in the human body. (news-medical.net)
  • More importantly, these microorganisms can even result in serious systemic infections like bacterial endocarditis, preterm labor, pneumonia, and cardiovascular diseases. (news-medical.net)
  • The major virulence factors associated with infections are the ability of microorganism to adhere to the tissue and initiate the interaction of bacterial cell with epithelial cells to cause infection. (interesjournals.org)
  • One of the most common chronic bacterial oral infections, periodontitis, affects the supporting structures of the teeth. (medscape.com)
  • Three CMBD derivatives showing an increasing proportion (5-14%) of benzylamide groups showed inhibition of bacterial adhesion increasing from 33 to 51% at 1 mg/ml. (unige.ch)
  • Unlike antibacterials that aim to inhibit cell growth, antivirulence therapies are based on the inhibition of bacterial virulence. (nature.com)
  • Some of these animal hosted Campylobacter species, such as Campylobacter jejuni and Campylobacter coli , can cause acute bacterial gastroenteritis in humans through consumption of contaminated food or water ( Galanis, 2007 ). (frontiersin.org)
  • Bacterial species are usually not harmful to their hosts, although there are exceptions. (frontiersin.org)
  • In the intestine of human and animals, Clostridium species, as one of the richest bacterial cluster, are mainly composed of Clostridium cluster IV and XIVa (Fig. 1 ). (biomedcentral.com)
  • Multidrug-resistant (MDR) Gram-negative bacterial species are an increasingly dangerous public health threat, and are now endemic in many areas of South Asia. (biomedcentral.com)
  • Multidrug-resistant (MDR) Gram-negative bacterial species are an established prominent international public health threat [ 1 ]. (biomedcentral.com)
  • A lack of comprehensive surveillance programs may result in the unchecked spread of MDR Gram-negative bacterial species and their associated resistance mechanisms. (biomedcentral.com)
  • Over 700 bacterial species co-inhabit healthy human mouth. (news-medical.net)
  • As a result of recent advances in culture-independent measurements of microbial communities, we know that the human gut is host to roughly a thousand different bacterial species [ 2 ]. (biomedcentral.com)
  • For example, bacterial endocarditis is one such condition that can affect the human heart. (news-medical.net)
  • ETEC attaches to and colonizes cells in the small intestine along the epithelial surface through the interaction of bacterial colonization factors (CFs) with the intestinal cell wall [ 15 , 16 ]. (biomedcentral.com)
  • An ideal transmucosal implant surface exposed to the oral cavity is recommended to be highly polished to resist bacterial colonization and it is expected to allow the formation of an epithelial seal that prevents plaque accumulation leading to peri-implantitis [ 5 , 6 ]. (hindawi.com)
  • We show that SrpB and SrpC play complementary adhesive roles involved in several steps of the colonization process: auto‐aggregation, biofilm formation and adhesion to a variety of host epithelial cells and components. (helmholtz-hzi.de)
  • Surface proteins involved in the adhesion of Streptococcus salivarius to human intestinal epithelial cells. (helmholtz-hzi.de)
  • 2010). It may have an effect on bacterial structure, influence the adhesion of bacterial to epithelial cells, and prevent colonization. (interesjournals.org)
  • The capability to adhere to epithelial cells is a key virulence trait, and genes codified in LAA pathogenicity island could be involved in the adhesion during the pathogenesis of LAA-positive STEC strains. (biomedcentral.com)
  • Both variations were shown to influence bacterial colonization in a murine infection model. (uni-muenchen.de)
  • The composition, configuration, and density of the proteins in the pellicle derived from the saliva and gingival crevicular fluid are largely dependent on the physical and chemical nature of the underlying surface and thus the properties of the surface influence bacterial adhesion through the pellicle [ 2 ]. (hindawi.com)
  • Our results show increased microbial diversity in the tumor microenvironment, with changes in the abundances of commensal and pathogenic bacterial taxa, including Fusobacterium and Providencia . (biomedcentral.com)
  • The pathogenic bacterial complex can lead to dental caries, periodontitis and gingivitis. (encyclopedia.pub)
  • To evaluate antibacterial behavior, we used two bacterial strains Gram-negative Escherichia coli ( E. coli ) and Gram-positive Staphylococcus aureus ( S. aureus ). (nature.com)
  • We previously developed an in vitro assay to study the Staphylococcus aureus adhesion-promoting effect of surface-adsorbed fibronectin on flat PMMA coverslips coated with a monolayer amount of fibronectin. (unige.ch)
  • In the dog, this includes Malassezia overgrowth (MOG) due to Malassezia pachydermatis and bacterial overgrowth (BOG) due to Staphylococcus intermedius . (vin.com)
  • Infrared spectroscopy, surface roughness, tube light deformation after compression, and Staphylococcus aureus colonization were assessed. (bvsalud.org)
  • Results: The number of immersions (reprocessing) had no influence on Staphylococcus aureus colonization of tubes (p=0.235), neither on chemical composition nor on roughness (p=0.621). (bvsalud.org)
  • A practical approach utilized in this study involves the preparation of an antibacterial thin film on the surfaces, which can effectively inhibit and reduce biofilm formation and bacterial adherence. (nature.com)
  • Conclusion: Reprocessing up to three times does not impair material properties and does not increase bacterial colonization of tube surfaces. (bvsalud.org)
  • Concise review of mechanisms of bacterial adhesion to biomaterial surfaces. (softtissuesupport.com)
  • The anti-biofouling effect of superhydrophobic surfaces is also desired in medical devices as it resists the adhesion of organic substances, such as blood cells and microorganisms. (afpm.org.my)
  • Dental plaque is a community of microorganisms found on the surface of teeth or other hard surfaces like dentures and embedded in a matrix of polymers of both host and bacterial origin. (encyclopedia.pub)
  • Then the lactic acid that comes from the bacterial fermentation of sucrose and other carbohydrates in the diet reach the enamel surface, which begins to dissolve, releasing Ca and PO 4 ions from the surfaces under the enamel [ 4 ] . (encyclopedia.pub)
  • Unique cell adhesion and invasion properties of Yersinia enterocolitica O:3, the most frequent cause of human Yersiniosis. (uni-muenchen.de)
  • In this study, we demonstrate unique cell adhesion and invasion properties of Y. enterocolitica serotype O:3 strains, the most frequent cause of human yersiniosis, and show that these differences are mainly attributable to variations affecting the function and expression of invasin in response to temperature. (uni-muenchen.de)
  • Multiple steps are involved during the pathogenesis of infection, including the colonisation of healthy individuals and invasion of the bacterium into the cerebrospinal fluid. (ox.ac.uk)
  • Most research on this bacterial pathogen to date has been done on strains infecting corn as the other diseases have been identified much more recently. (wikipedia.org)
  • To be effective against colonisation, vaccines must induce local immune responses, which promote elimination of the pathogen, break the chain of transmission, and induce herd immunity. (bmj.com)
  • 1, 2 This review approaches the role of mucin degrading enzymes from the potential interaction of micro-organisms with the cervical mucus barrier, and discusses the contribution that mucin degrading enzymes may make to microbial colonisation of the reproductive tract. (bmj.com)
  • Microbial overgrowth may be defined as a clinical disease due to the colonisation of the skin by microbes. (vin.com)
  • Catheter-related urinary tract infection (UTI) occurs because urethral catheters inoculate organisms into the bladder and promote colonization by providing a surface for bacterial adhesion and causing mucosal irritation. (blogspot.com)
  • Morphology and bacterial colonization of tooth/ceramic restoration interface after different cement excess removal techniques. (unicamp.br)
  • Bacterial morphology was examined using an SEM. (hindawi.com)
  • Considered generally recognized as safe (GRAS) by the Food and Drug Administration and recently approved by the U.S. Dept. of Agriculture for use on fresh beef, ALF can be sprayed onto carcasses to help prevent bacterial contamination during processing or can be applied to a subprimal or finished beef surface prior to final packaging to inhibit bacterial growth and extend shelf life. (ift.org)
  • Proanthocyanins aren't the only compounds that have anti-adhesion properties and cranberries aren't the only fruits beneficial for urinary tract health. (reddremedies.com)
  • However, excessive and indiscriminate use of antibiotics has resulted in the development of antibiotic resistance among bacterial strains 14 . (nature.com)
  • The nanotubular TiO 2 surface layers play an important role in the improvement of osseointegration through the enhancement of bone cell adhesion, differentiation, ALP activity, bone matrix deposition, apatite deposition rates [ 15 ], and hemocompatibility of Ti and Ti-based materials [ 16 - 18 ]. (hindawi.com)
  • As a matrix for cell adhesion and proliferation in combination with cell mediated resorption, OsseoConduct™ produces normal bone in a short time period. (bonegrafting.com)
  • Field emission scanning electron microscopy (FE-SEM) images verified that both E. coli and S. aureus cells were physically deformed and damaged the bacterial cell ultrastructure was observed. (nature.com)
  • Another category of substituted dextrans having a variable proportion (2-26%) of sulfonated benzylamide groups (CMBDS) produced active inhibition of S. aureus adhesion. (unige.ch)
  • In comparison to these heparin-like dextran derivatives, native heparin produced inhibition values of S. aureus adhesion which were intermediate between those of CMBD and CMBDS compounds. (unige.ch)
  • In conclusion, S. aureus adhesion on fibronectin-coated biomaterials can be efficiently blocked in vitro by soluble compounds such as dextran derivatives. (unige.ch)
  • We report here that myricetin, but not its glycosylated form, can remarkably decrease the production of several S. aureus virulence factors, including adhesion, biofilm formation, hemolysis and staphyloxanthin production, without interfering with growth. (nature.com)
  • Due to being relatively easy to work with in laboratory research, P. stewartii has been used to study a range of processes in bacterial physiology including quorum sensing, bacterial pigment production, endoglucanase enzymes, and siderophore-mediated iron acquisition. (wikipedia.org)
  • Biological role of pigment production for the bacterial phytopathogen Pantoea stewartii subsp. (wikipedia.org)
  • These data are evidence for a synergistic action of fimbrial operons during colonization of the mouse intestine and the development of murine typhoid fever. (elsevierpure.com)
  • The phrase "race for the surface" was coined by Gristina in 1987 to describe the competition between bacterial adhesion and tissue integration [ 3 ]. (hindawi.com)
  • Proven osseointegration and soft-tissue adhesion thanks to the hydrophilic sand-blasted, acid-etched Zerafil™ implant surface. (nobelbiocare.com)
  • These findings highlight that adding Cu to Ti can improve the antibacterial ability of the surface while inhibiting bacterial adherence. (nature.com)
  • This study evaluated the surface topography and bacterial adhesion of a hybrid ceramic and a nano ceramic resin composite after different surface finishes. (unicamp.br)
  • The specimens were analyzed regarding surface roughness parameters (Ra, Rz, Rq), sterilized and subjected to bacterial adhesion. (unicamp.br)
  • The type of material and surface finish system significantly interfered with surface roughness parameters and bacterial adhesion. (unicamp.br)
  • TPS systems are TpsA for translocated proteins to the bacterial surface and TpsB for the transporter proteins. (biomedcentral.com)
  • Other cancer-associated bacterial taxa have been identified, including Escherichia coli strain NC101 and Bacteroides fragilis , each with a proposed mechanism of interaction with colon cancer [ 15 ]. (biomedcentral.com)
  • Bacterial adhesion and proliferation are serious and increasing concerns in everyday life, and are responsible for significant damage in several industries, including textile, water treatment, marine transport, medicine and food packaging. (mdpi.com)
  • Genome analysis of C. concisus strains isolated from saliva samples has identified a bacterial marker that is associated with active Crohn's disease (one major form of IBD). (frontiersin.org)
  • Biofilm formation requires three different stages: cell attachment to a solid substrate, adhesion, and growth. (intechopen.com)
  • Bilberries, blueberries, cherries and raspberries contain polyphenols, ellagic acid, and other antioxidants that impact bacterial colonization of the bladder wall. (reddremedies.com)
  • Three glycosylated serine-rich repeat proteins play a pivotal role in adhesion and colonization of the pioneer commensal bacterium, Streptococcus salivarius. (helmholtz-hzi.de)
  • The pioneer colonizer and commensal bacterium of the human gastrointestinal tract, Streptococcus salivarius, has strong adhesive properties but the molecular determinants of this adhesion remain uncharacterized. (helmholtz-hzi.de)
  • Identification of New Factors Modulating Adhesion Abilities of the Pioneer Commensal Bacterium Streptococcus salivarius. (helmholtz-hzi.de)
  • The continued and prolonged use of antibiotics can lead to bacterial resistance and negative impacts on probiotic populations in the body, which can lead to impaired immune system function. (reddremedies.com)
  • The extract significantly inhibited biofilm formation and bacterial adhesion to HT-29 colorectal cells by a highly adherent multidrug-resistant K. pneumoniae. (blueberry.org)
  • This work identifies bacterial taxa significantly correlated with colorectal cancer, including a novel finding of an elevated abundance of Providencia in the tumor microenvironment. (biomedcentral.com)
  • In general, Gram‐positive bacterial genomes have a unique SRR glycoprotein‐encoding gene. (helmholtz-hzi.de)
  • Actually, inflammation is the most common pathological symptom of periodontal disease and the agent of inflammatory processes is bacterial plaque [2,3]. (bvsalud.org)
  • The direct mechanism is connected with angiotensin-converting enzyme II (ACE-2) receptors, while the indirect mechanism is connected with inflammatory pathways and bacterial superinfections. (encyclopedia.pub)
  • Interactions between Neisseria meningitidis and human cells that promote colonisation and disease. (ox.ac.uk)
  • Neisseria meningitidis is the leading cause of bacterial meningitis, a potentially fatal condition that particularly affects children. (ox.ac.uk)
  • Micro-organisms depend on successful colonisation of the host in order to reproduce and multiply. (bmj.com)
  • they play a key role in adhesion and colonisation of host cells. (kent.ac.uk)
  • Bacterial adhesion is a critical step for colonization of the host. (helmholtz-hzi.de)
  • SrpA, SrpB and SrpC are the main factors underlying the multifaceted adhesion of S. salivarius and, therefore, play a major role in host colonization. (helmholtz-hzi.de)
  • Bacterial adhesion is a general strategy for host-microbe and microbe-microbe interactions. (dentalreach.today)
  • Alterations of this bacterial community are correlated with host health, including diseases ranging from diabetes and obesity to Crohn's disease and arteriosclerosis [ 3 ]. (biomedcentral.com)
  • We found bacterial contamination within 24 hours in this system in patients on ventilatory support in intensive care. (afpm.org.my)
  • Antibiotic sensitivity patterns showed concordance of bacterial cultures from dental plaque and oropharyngeal cavity in 13 patients. (who.int)
  • The adhesion test for the E.coli was applied by method of slide hemagglutination of erythrocyte cells ( Iwahi et al. (interesjournals.org)
  • 1983). Bacterial cells from individual colonies was picked up by sterile loop and mixed with one drop of normal saline on microscope slide to form homogenous emulsion. (interesjournals.org)
  • The myocardial nicheplays a critical role in directing the function and fate of cardiomyocytes;therefore, engineering a biomimetic scaffold holds excellent promise.We produced an electroconductive cardiac patch of bacterial nanocellulose(BC) with polypyrrole nanoparticles (Ppy NPs) to mimic the naturalmyocardial microenvironment. (ibecbarcelona.eu)
  • Smaller bacterial adhesion values (CFU/mL) were observed for ENDD and ENVT, which differed significantly from the other groups, except ENCTL. (unicamp.br)
  • We also describe the predicted metabolic pathways and enzymes differentially present in the tumor-associated microbiome, and show an enrichment of virulence-associated bacterial genes in the tumor microenvironment. (biomedcentral.com)
  • These genes are encoded in LAA, and are virulence factors that participate in adhesion and autoaggregation. (biomedcentral.com)
  • Genes codified in LAA could be involved in the adhesion during the pathogenesis of LAA-positive STEC strains, and little is known about the specific virulence factors that contribute to these pathogeneses. (biomedcentral.com)
  • Meier R, Hauser-Gerspach I, Lüthy H, Meyer J. Adhesion of oral streptococci to all-ceramics dental restorative materials in vitro. (unicamp.br)
  • 20%) adhesion inhibition at 1 mg/ml, dextrans increasingly substituted with carboxylic and benzylamide groups (CMBD) exhibited increasing anti-adhesive activities. (unige.ch)
  • Any drug impairing crucial processes for bacterial life will inevitably lead to the development of drug-resistant strains, whereas the inhibition of biofilm formation might prevent the onset of bacterial resistance. (intechopen.com)