• Cancer
  • In patients with locally advanced colon cancer (high risk stage II and stage III), curative surgery followed by adjuvant FOLFOX-4 chemotherapy has become the standard of care. (clinicaltrials.gov)
  • Preoperative chemotherapy is an attractive concept for locally advanced colon cancer and has the potential to impact upon both of these causes of failure. (clinicaltrials.gov)
  • ECKINOXE is a multicenter randomized phase II trial designed to evaluate efficacy (response rate) and feasibility (safety, tolerance) of these two chemotherapy regimens (FOLFOX-4 alone and FOLFOX-4+Cetuximab) in a neoadjuvant strategy in patients with locally advanced colon cancer. (clinicaltrials.gov)
  • Mucin production by human colonic carcinoma cells correlates with their metastatic potential in animal models of colon cancer metastasis. (mysciencework.com)
  • Patients with mucinous colorectal cancers characteristically present with advanced disease, however, the relationship between mucin production by colon cancer cells and their metastatic potential remains unclear. (mysciencework.com)
  • We therefore sought to define the relationship between mucin production by human colon cancer cells and metastatic ability by employing animal models of colon cancer metastasis. (mysciencework.com)
  • These data suggest that mucin production by human colon cancer cells correlates with their metastatic potential and affects their ability to colonize the liver in experimental model systems. (mysciencework.com)
  • high
  • LS LiM 6, a colon carcinoma cell line with high liver metastasizing ability during cecal growth in nude mice produced twofold more metabolically labeled intracellular mucin and secreted four- to fivefold more mucin into the culture medium compared to poorly metastatic parental line LS174T. (mysciencework.com)
  • Text
  • Colon (anatomy) This article incorporates text in the public domain from the 20th edition of Gray's Anatomy (1918) Physiology: 6/6ch2/s6ch2_30 - Essentials of Human Physiology Anatomy figure: 37:06-08 at Human Anatomy Online, SUNY Downstate Medical Center - "The large intestine. (wikipedia.org)