• Cyanocobalamin is a form of vitamin B 12 and is one of the class of B 12 vitamins or cobalamin compounds that includes vitamin B 12a (hydroxocobalamin), vitamin B 12b (aquacobalamin), vitamin B 12c (nitrilocobalamin), methyl B 12 (methylcobalamin) and coenzyme B 12 (5′deoxyadenosine cobalamin). (justia.com)
  • loop kappa p21 D cell 4( ABCD4) is shown to reduce the CD127 performance of cobalamin( Cbl membrane parking B12) into the mitochondrion, interacting it ED for the composition of Cbl lives. (evakoch.com)
  • T changes with key GAB2 and is the raft of PIP3 in the liver, which contains heparin-dependent membrane leader sites like BTK, PLC-gamma, AKT and PDK. (evakoch.com)
  • protein_coding" "AAC74323","adhE","Escherichia coli","fused acetaldehyde-CoA dehydrogenase/iron-dependent alcohol dehydrogenase/pyruvate-formate lyase deactivase [Ensembl]. (ntu.edu.sg)
  • Functional identification in Lactobacillus reuteri of a PocR-like transcription factor regulating glycerol utilization and vitamin B 12 synthesis. (uva.nl)
  • The present invention relates generally to vitamin B12 nasal spray compositions and methods of using the same in the treatment of vitamin B12 deficiency and various disorders that are related to such deficiency. (justia.com)
  • Based on in silico thermodynamic optimization, minimal protein requirement analysis, and ensemble modeling-based robustness analysis, we identified the top two significant flux control sites, i.e., acetoacetyl-coenzyme A (CoA) transferase (AACT) and acetoacetate decarboxylase (AADC), overexpression of which could lead to increased isopropanol production. (bvsalud.org)
  • Insulin is used as a drug to control insulin-dependent diabetes mellitus (DIABETES MELLITUS, TYPE 1). (lookformedical.com)
  • The therapeutic efficacy of biotin was evaluated in 43 patients with non-insulin dependent diabetes mellitus. (researchgate.net)
  • These observations suggest that the biotin administration ameliorates abnormal glucose metabolism in diabetic patients, presumably by enhancing the activity of the biotin-dependent enzyme, pyruvate carboxylase, with a subsequent promotion of glucose utilization for the entry into the tricarboxylic acid cycle. (researchgate.net)
  • Background Biotin is a water-soluble vitamin acting as a covalently bound coenzyme in regulating energy production. (researchgate.net)
  • Binding-protein-dependent transport system inner membrane component [Interproscan]. (ntu.edu.sg)
  • Herein, we use a combination of stopped-flow spectroscopy, targeted mutagenesis, TD-DFT calculations, high-energy resolution fluorescence detection X-ray absorption spectroscopy, and electron paramagnetic resonance spectroscopy to study two transient intermediates that together form a protective pathway built into the active sites of copper-dependent lytic polysaccharide monooxygenases (LPMOs). (bvsalud.org)
  • Here, a series of crystal structures of the CarH B12-binding domain after illumination suggest formation of unforeseen intermediate states prior to tetramer dissociation. (bvsalud.org)
  • Combined with detailed solution spectroscopy and computational studies, these data demonstrate the CarH photoresponse integrates B12 photo- and redox-chemistry to drive large-scale conformational changes through stepwise Co-ligation changes. (bvsalud.org)
  • The motion of phospholipid molecules within the lipid bilayer, dependent on the classes of phospholipids present, their fatty acid composition and degree of unsaturation of the acyl chains, the cholesterol concentration, and temperature. (lookformedical.com)