• Transaminase
  • Transamination, or the transfer of an amine (or NH2) group from an amino acid to a keto acid by an aminotransferase (also known as a "transaminase"), was first noted in 1930 by D. M. Needham, after observing the disappearance of glutamic acid added to pigeon breast muscle. (wikipedia.org)
  • amino
  • L-alanine + α-ketoglutarate ⇌ pyruvate + L-glutamate ALT (and all aminotransferases) require the coenzyme pyridoxal phosphate, which is converted into pyridoxamine in the first phase of the reaction, when an amino acid is converted into a keto acid. (wikipedia.org)
  • Because of their biological significance, amino acids are important in nutrition and are commonly used in nutritional supplements, fertilizers, and food technology. (wikipedia.org)
  • The enhancement of immune responsiveness observed in mice fed the 28% L diet was moderately reduced by the addition of phenylalanine to the diet, indicating that the lower level of this amino acid in the L protein may be of some significance. (wikipedia.org)
  • efficacy
  • Its efficacy is further substantiated by pre-clinical data obtained from the vacuous chewing movement (VCM) model in rats, a model we employ ourselves in investigating the relationship between D2 occupancy and TD. (clinicaltrials.gov)
  • practice
  • The available noninvasive diagnostic assessments including APRI, FIB-4, and FibroTest were also less optimal, although they have been increasingly accepted in clinical practice. (hindawi.com)
  • Clinical practice guidelines by the American College of Gastroenterology have recommended corticosteroid treatment. (wikipedia.org)
  • diagnosis
  • Based on our clinical experiences in diagnosis and treatment with Traditional Chinese Medicine (TCM) in CHB patients with fibrosis, TCM syndrome elements would improve the diagnosis performance when combined with the markers with confirmed diagnostic effects in these patients. (hindawi.com)
  • data
  • The demographic, clinical, and pathological data were retrospectively collected from 709 CHB patients who had ALT less than 2 times the upper limit of normal from April 2009 to October 2012. (hindawi.com)
  • series
  • The first involves a series of instrumental and clinical measures that were developed as a battery for the assessment of antipsychotic-induced parkinsonism and TD. (clinicaltrials.gov)