• The unfavourable prognosis in BRCA2-associated breast cancer seems, to a great extent, to be a consequence of the higher clinical stage at diagnosis. (lu.se)
  • We conducted this research to investigate the clinical characteristics and outcomes of OCCC and to provide additional supporting evidence to aid in the clinical diagnosis and management. (biomedcentral.com)
  • Therefore, the purpose of our research is to assess the clinical characteristics and outcomes of patients with OCCC, and to provide additional supporting evidence to aid in the clinical diagnosis and management of OCCC. (biomedcentral.com)
  • Diagnosis is clinical and based largely on patient history. (medscape.com)
  • At present, the main treatment principles of GC are early diagnosis, early surgery, and postoperative adjuvant chemotherapy, so as to improve patients' prognosis of patients. (researchsquare.com)
  • Even without a supporting history, the diagnosis of AHT can still be made with confidence on the basis of characteristic clinical findings. (aao.org)
  • In conclusion, intraventricular liponeurocytoma has a favorable clinical course, radiological features may be useful in the diagnosis of this rare tumor before surgery. (oncotarget.com)
  • If unable to make the diagnosis of nicotine stomatitis by clinical appearance or if the lesion does not resolve after cessation of smoking, perform a 5-mm punch biopsy or scalpel biopsy. (medscape.com)
  • cause the diagnosis is based on clinical cri- · colour jet seen in at least 2 planes teria, it is still under-diagnosed or over- · mosaic colour jet diagnosed in different settings [ 3 ]. (who.int)
  • Diagnosis is clinical, with laboratory and usually imaging tests to identify the cause. (msdmanuals.com)
  • For example, in the recent study that used MRS in addition to electronic health records (EHR) to predict clinical phenotypes, the methylation was measured after clinical diagnosis. (cdc.gov)
  • Elevated CRP often indicates a worse prognosis in AIS patients, but it is not clear whether it can predict the patient's functional outcome in LAA patients. (hindawi.com)
  • Patients with FCC with metastases of the liver had a worse prognosis than their MCC counterparts. (hindawi.com)
  • Furthermore, patients with liver metastatic FCC have a worse prognosis than those with MCC. (hindawi.com)
  • 60 g/L ( p = 0.027), and bone marrow hemophagocytosis ( p = 0.034) correlated with worse prognosis. (biomedcentral.com)
  • The most frequent tumor suppressor miRs were miR-126, miR-199b and miR-22 and the hypoexpression of these miRs was associated with distant metastasis, worse prognosis and a higher risk of disease relapse (worse disease-free survival). (biorxiv.org)
  • Cite this: These Adverse Events Linked to Improved Cancer Prognosis - Medscape - Sep 28, 2023. (medscape.com)
  • The authors ask whether disparate results of recent consensus conferences, which ``good old'' clinical markers, if optimally analysed, might have attempted, using simple criteria, to define ``low- have a similar discriminating power with regard to breast risk'' patients for whom adjuvant chemotherapy should cancer prognosis as the microarray gene expression pro- not be recommended. (lu.se)
  • Ren MY, Li J, Wu YX, Li RM, Zhang C, Liu LM, Wang JJ, Gao Y. Clinical characteristics and prognosis of orbital solitary fibrous tumor in patients from a Chinese tertiary eye hospital. (wjgnet.com)
  • Total LN number, positive LN number, clinical treatment, tumor marker, and patients' prognosis between two groups were compared. (researchsquare.com)
  • Cerebellar liponeurocytoma is a rare central nervous system tumor, we investigate its biological behaviors and clinical prognosis to improve the understanding of this tumor. (oncotarget.com)
  • The two groups were then compared for demographic profiles, clinical manifestations of PC, features of the tumor and fatal outcomes. (bioseek.eu)
  • Clinical features, tumor size and prognosis of PC are similar in people with and without diabetes. (bioseek.eu)
  • Combining MRS with other clinical information was found to have a better predictive value for tumor prognosis. (cdc.gov)
  • Journal of Clinical Oncology , 31 (12), 1576-1582. (eur.nl)
  • In the study, presented at this year's ASCO Gastrointestinal Symposium , Richard Francis Dunne, MD, MS, of Wilmot Cancer Institute at the University of Rochester Medical Center in New York, and colleagues identified a significant association between cachexia and poor prognosis in eight of 13 studies of pancreatic cancer and nine of 13 studies of colorectal cancer. (medpagetoday.com)
  • In 2020, a study used MRS to predict the prognosis of colorectal cancer patients. (cdc.gov)
  • this clinical situation requires adjuvant chemotherapy and radiation therapy. (aao.org)
  • Randomised clinical trials have shown an overall duction of techniques that can simultaneously evaluate benefit for both adjuvant chemotherapy and endocrine the expression of large numbers of tumour genes. (lu.se)
  • Despite growing knowledge of its biology, no molecular biomarkers are currently used in routine clinical practice to determine prognosis or aid clinical decision making. (eur.nl)
  • A short-cut review was performed to evaluate whether the RIFLE or AKIN score for acute renal impairment is the best way to determine prognosis. (bmj.com)
  • Children with intraocular retinoblastoma who have access to modern medical care have a very good prognosis for survival (>95% in industrialized countries). (aao.org)
  • The treatment of cervical cancer has a good prognosis if diagnosed early. (who.int)
  • These may be valuable biomarkers for the prognosis and the potential therapeutic targets of cervical cancer. (medscimonit.com)
  • Specific tissue miRs are shown to be promising prognostic biomarkers in patients with CRC, given their strong association with the prognostic aspects of these tumors, however, new studies are necessary to establish the sensibility and specificity of the miRs in order to use them in clinical practice. (biorxiv.org)
  • A limited number of biomarkers have been used to predict the prognosis and monitor the outcomes of patients with breast cancer (BC), such as lactate dehydrogenase (LDH), which is an independent prognostic marker for BC and the Ki-67 index, which is of utmost importance to the prognosis and molecular typing of patients with BC ( 1 ). (spandidos-publications.com)
  • This handbook discusses the risk factors of cerebral palsy, as well as the therapeutic management options, and long-term prognosis of the condition. (novapublishers.com)
  • We aimed to assess the burden, outcome, risk factors, and long-term prognosis of cryptogenic TIA and stroke. (nih.gov)
  • A global systematic review and meta-analysis on the emerging evidence on risk factors, clinical characteristics, and prognosis of multisystem inflammatory syndrome in adults (MIS-A). (bvsalud.org)
  • The multisystem inflammatory syndrome in adults (MIS-A) has emerged, similar to those in children associated with SARS-CoV-2 ( severe acute respiratory syndrome coronavirus 2 ) [multisystem inflammatory syndrome in children (MIS-C)]. This review aimed to analyze the risk factors , clinical course , and prognosis of MIS-A. (bvsalud.org)
  • There are increasing evidences that show that the prognosis of patients with acute ischemic stroke (AIS) is closely related to the inflammatory response. (hindawi.com)
  • Patients were not required to give informed consent to the study because the analysis used anonymous clinical data that were obtained after each patient agreed to treatment by written consent. (wjgnet.com)
  • Article abstract- The authors reviewed the clinical features and outcome of Miller Fisher syndrome (MFS) for 50 consecutive patients with MFS including 28 patients who received no immunotherapy. (neurology.org)
  • 1 Because MFS is a rare disorder, and few studies have been made of a large number of consecutive patients with MFS, 2 the frequency and characteristics of neurologic symptoms and signs and natural history and prognosis are not fully understood. (neurology.org)
  • To shed light on these clinical issues, we reviewed data for 50 consecutive patients with MFS. (neurology.org)
  • All 53 patients with MFS with the clinical triad of MFS (ophthalmoplegia, ataxia, and areflexia) and acute onset without major limb weakness or other signs suggestive of CNS involvement were selected. (neurology.org)
  • We followed the clinical courses of the latter 28 patients focusing on amelioration of the clinical triad, except areflexia. (neurology.org)
  • Before the introduction of highly active antiretroviral therapy (HAART), vacuolar myelopathy (VM) occurred in 5-20% of adult HIV patients in clinical studies and in 25-55% of adult HIV patients in histologic studies. (medscape.com)
  • This was a retrospective study investigating the clinical characteristics and survival outcomes of 86 patients with OCCC treated at our center between January 2010 and March 2020. (biomedcentral.com)
  • Due to this inherent chemoresistance, the prognosis of patients with OCCC is extremely poor, especially at advanced stage. (biomedcentral.com)
  • We conducted a prospective study to assess long-term clinical, pulmonary function testing, and chest computed tomography (CT) imaging findings after patients were discharged from hospital. (ox.ac.uk)
  • In order to increase the detection rate of lymph nodes (LNs) in radical gastrostomy, we applied indocyanine green (ICG) tracing and Ex vitro anatomical sorting to LNs dissection, and explored the guiding role of LNs number detected in the prognosis of patients with gastric cancer (GC). (researchsquare.com)
  • The clinical data of 88 GC patients who underwent D2 radical gastrostomy were retrospectively analyzed, and they were divided into ICG group and non-ICG group according to ICG usage and LN sorting method. (researchsquare.com)
  • ICG tracing combined with Ex vitro anatomical sorting can significantly improve the detection rate of total LNs and positive LNs, which has a positive impact on patients' long-term prognosis. (researchsquare.com)
  • Therefore, in D2 radical gastrostomy, increasing the detected number of LNs is very important to improve patients' prognosis. (researchsquare.com)
  • 2 A good model may allow the reasonably reliable classification of patients into risk groups with different prognoses. (bmj.com)
  • Various statistical or clinical factors may lead a prognostic model to perform poorly when applied to other patients. (bmj.com)
  • There will clearly be many similarities between the two sets of patients and between the clinical and laboratory techniques used in evaluating them. (bmj.com)
  • We retrospectively analyzed the clinical, radiological and histopathological findings as well as follow-up data of two patients with intraventricular liponeurocytomas in Beijing Tiantan Hospital between July 2000 and July 2016. (oncotarget.com)
  • The main clinical manifestations of the two patients were headache. (oncotarget.com)
  • The purpose of this study was to compare the metastatic pattern and prognosis of female colon cancer (FCC) to that of male colon cancer (MCC) to ascertain the independent factors impacting the prognosis of patients with FCC. (hindawi.com)
  • Liver and lung were the two most common sites of solitary metastases in CC, and among patients with solitary metastases in CC, patients who had lung metastases had a better prognosis than those who developed other types of metastasizes. (hindawi.com)
  • Emphasis on screening for colon cancer in women and additional clinical care should be paid for, especially for patients with FCC with metastatic liver cancer. (hindawi.com)
  • We conducted cross-sectional and longitudinal studies of patients with metastatic FCC to determine their clinicopathological characteristics and differences from patients with metastatic MCC and identify independent factors that affect the prognosis of patients with FCC. (hindawi.com)
  • Patients in the early stages of mesothelioma are better candidates for surgery, which can improve their prognosis and life expectancy. (asbestos.com)
  • Some patients may be eligible for mesothelioma clinical trials that test newer therapies. (asbestos.com)
  • Patients with non-malignancy-associated HLH do not have better survival, although their prognosis is relatively better in clinical practice. (biomedcentral.com)
  • We retrospectively reviewed patients with malignancy- and non-malignancy-associated HLH at our institution and compared the clinical characteristics, treatment response, overall survival time, and prognostic factors of the two groups. (biomedcentral.com)
  • Clinical features, management and prognosis of 37 MB-DLBCL patients and 63 'controls' (stage-IV DLBCL and skeletal involvement) were analysed. (qxmd.com)
  • Thus, MB-DLBCL patients exhibit a significantly better prognosis compared to patients with advanced-stage DLBCL, and should be treated with conventional anthracycline-based chemotherapy, keeping intensified treatment for relapsing cases, considering involved-field radiotherapy, and CNS prophylaxis in high-risk patients. (qxmd.com)
  • We retrospectively reviewed the clinical files of 122 patients with PC, and divided them into two groups: those with diabetes (56 patients) and those without diabetes (66 patients). (bioseek.eu)
  • BioHope is a leading biomedical company specialized in the development of novel diagnostic tools and advanced therapies for clinical management of organ transplanted patients. (europa.eu)
  • Thanks to the wide experience in molecular biology and medicine of the company´s team and the extensive research performed by the company in the field of immunology, BioHope has developed and patented a disruptive tool for efficient global clinical management of patients undergoing a kidney transplant. (europa.eu)
  • On the whole, the present study demonstrates that the partitioning calculation of the Ki‑67 index can be used to judge the prognosis of patients with BC accurately. (spandidos-publications.com)
  • The prognosis of patients with different molecular subtypes of BC may be associated with the different Ki‑67 index. (spandidos-publications.com)
  • The potential to achieve the accurate prognosis of patients with BC with the Ki-67 index is dependent on whether this index is associated with the molecular subtype of BC, the possibility of patients with different molecular types to be applicable to the same Ki-67 index, and requires this index to possess an interval value, facilitating clinical pathologists to operate and increase the critical application value. (spandidos-publications.com)
  • In the past, transla- progesterone receptor (PgR) expression, and all of the tional research focused on single biological markers following features: pT 6 2 cm, grade I, age P 35 years which could putatively discriminate patients' prognosis should be considered in this low-risk category, whereas or treatment response. (lu.se)
  • It is not meant to replace clinical judgment or specialist consultation but rather to strengthen clinical management of these patients and provide to up-to-date guidance. (who.int)
  • Determining the stage of cancer is important because it helps doctors make treatment plans and predict patient prognoses. (asbestos.com)
  • MRS has a potential to be used with EHR to predict phenotypes in the clinical setting. (cdc.gov)
  • Impact of diabetes mellitus on clinical presentation and prognosis of pancreatic cancer. (bioseek.eu)
  • The aim of this study was to investigate possible effects of diabetes mellitus on clinical manifestations and prognosis of pancreatic cancer (PC). (bioseek.eu)
  • However, laparoscopic minimally invasive surgery will affect operator's hand feeling, as a result, the exact location of tumors and LNs cannot be accurately located via visual observation and clinical experience, thus affecting the detection rate of LNs. (researchsquare.com)
  • No radiological or clinical evidence of recurrence of the tumors was observed in their follow-up surveys. (oncotarget.com)
  • Our collated findings will help clinicians identify the typical presenting symptoms and optimal management of MIS-A. Further research is required to understand the long-term prognosis and the correlation between coronavirus disease 2019 (COVID-19) and MIS-A to understand its pathogenesis and clinical spectrum. (bvsalud.org)
  • Partitioning calculation was used to judge the Ki‑67 index and the molecular type was classified according to the 2019 Chinese Society of Clinical Oncology guidelines in 199 cases of BC. (spandidos-publications.com)
  • In 2019, it was reported in the Guidelines of the Chinese Society of Clinical Oncology (CSCO) that the critical value of Ki-67 should be determined according to the practical situation of each laboratory ( 4 ). (spandidos-publications.com)
  • This is the first edition of this document for novel coronavirus, an adaption of WHO Clinical management of severe acute respiratory infection when MERS-CoV infection is suspected publication (2019). (who.int)
  • For queries, please email [email protected] with `2019-nCoV clinical question' in the subject line. (who.int)
  • Clinical features, management and prognosis of multifocal primary bone lymphoma: a retrospective study of the international extranodal lymphoma study group (the IELSG 14 study). (qxmd.com)
  • With advantages of being simple to perform with only 5 parameters to consider and a quick prediction at 24 hours following admission, you are unsure if BISAP score is accurate in predicting clinical severity in acute pancreatitis when compared with the more established Ranson's/modified Glasgow score. (bestbets.org)
  • The clinical bottom line is that both score are as good as predicting death following presentation with acute renal failure. (bmj.com)
  • Karalliedde (Karalliedde and Senanayake 1989) first described the syndrome in 1987 and observed that, although clinical findings occurred in a delayed fashion, they were described as acute in onset. (cdc.gov)
  • Among the examined polymorphisms, DBP1 (rs7041) TT and CDX2 (rs11568820) AA/AG genotypes were markers of better prognosis, even with multivariate adjustment. (naturalmedicinejournal.com)
  • Finding a mesothelioma specialist at a top mesothelioma treatment center is the best way to benefit from the latest therapies and improve a mesothelioma prognosis. (asbestos.com)
  • Prognosis and Determinants of Asthma Morbidity in World Trade Center Rescue and Recovery Workers' will provide a detailed assessment of the clinical presentation, relationship with exposure, treatment needs, evaluation of the influence of comorbidities on disease presentation, and the impact of asthma on the quality of life of WTC workers. (cdc.gov)
  • Treatment and prognosis for intermediate syndrome. (cdc.gov)
  • Prognosis and treatment of paraquat poisoning: a review of 28 cases. (cdc.gov)
  • Treatment and prognosis are also described. (cdc.gov)
  • We aimed to describe the incidence, prognosis, and focus of infection of bacteraemia with NFE. (lu.se)
  • PCP is often the initial clinical sign of HIV infection, particularly among infants. (cdc.gov)
  • Complex study addressing all 9 clinical scores and 2 laboratory markers. (bestbets.org)
  • however, laboratory testing is not necessary nor routinely performed in clinical practice. (cdc.gov)
  • The case can be confirmed if laboratory testing was not performed because either a predominant amount of clinical and nonspecific laboratory evidence of a particular chemical was present or the etiology of the agent is known with 100% certainty. (cdc.gov)
  • many clinicians were hoping that it was a Data obtained included clinical profile disease of the past, anxieties were renewed and standard laboratory investigations in- when outbreaks were reported in several cluding complete blood count, sedimenta- areas around the United States [ 7 ]. (who.int)
  • SDF-1 and NF-κB are associated with the prognosis of a wide range of cancers, but their value in cervical cancer remains controversial. (medscimonit.com)
  • The aim of this study was to investigate the expression of SDF-1and NF-κB in cervical cancer and their significance in clinical prognosis. (medscimonit.com)
  • As adjuvant therapies have cular biology of breast cancer, clinical decision-making costs and side-effects associated with them, various still largely relies on pathological staging, grading and prognostic criteria have been established to guide the steroid receptor status. (lu.se)
  • Patterns of chromosomal imbalances defines subgroups of breast cancer with distinct clinical features and prognosis. (lu.se)
  • Sources for each exposure are discussed along with relevant historical aspects Pathophysiological mechanisms are addressed in conjunction with clinical presentation. (cdc.gov)
  • A study reports high levels of CRP associated with clinical prognosis in the time window between 12 and 72 hours after ischemic stroke [ 17 , 18 ]. (hindawi.com)
  • While the vasculitic subtype seemed to have poorer prognosis in Sun's research, other study has shown controversial result[2]. (ashdin.com)
  • A clinical study using strict recovery criteria (concurrent remission of positive and negative symptoms and adequate social and vocational functioning continuously for two years) found a recovery rate of 14% within the first five years. (wikipedia.org)
  • A 5-year community study found that 62% showed overall improvement on a composite measure of clinical and functional outcomes. (wikipedia.org)
  • A clinical study that took into account concurrent remission of positive and negative symptoms, and adequate social and vocational functioning continuously for two years, found a recovery rate of 14% within the first five years. (wikipedia.org)
  • The aim of the present study was to perform the accurate prognosis of different molecular types breast cancer (BC) by using the partitioning calculation method of the Ki‑67 index. (spandidos-publications.com)
  • CRP is of clinical importance as an early prognostic factor after stroke because it is an easily measured and clinically common indicator of inflammation. (hindawi.com)
  • Prognostic models are of little clinical value unless they are shown to work in other samples. (bmj.com)
  • Here, we describe the clinical characteristics, prognostic factors, and survival outcomes of malignancy-associated HLH compared to that of non-malignancy-associated HLH. (biomedcentral.com)
  • We aimed to distinguish between malignancy-associated and non-malignancy-associated HLH, compare their clinical features and prognostic significance, and analyze the difference between the two conditions. (biomedcentral.com)
  • Validation of the consensus reached for the definition and classification of cancer cachexia "should aid clinical trial design, development of practice guidelines, and, eventually, routine clinical management," the team wrote. (medpagetoday.com)
  • The routine assessment of weight change in clinical practice could inform early disease management strategies that improve prognosis. (medpagetoday.com)
  • Paraquat poisoning: clinical features and immediate general management. (cdc.gov)
  • The aim of this review is to describe the differences in the phenotypic expression and clinical outcomes of Sarc+ and Sarc− HCM and to briefly discuss the current knowledge about HCM caused by rare non-sarcomeric mutations. (mdpi.com)
  • Clinical features. (neurology.org)
  • Transgenic mice that express HIV gene products in oligodendrocytes develop clinical and histologic features that resemble the human disease. (medscape.com)
  • The clinical features were compared using the Mann-Whitney U and χ 2 tests. (biomedcentral.com)
  • The positive SDF-1or NF-κB expression is significantly correlated with poor prognosis. (medscimonit.com)
  • Expression of hepsin and pim-1 proteins was significantly correlated with measures of clinical outcome. (nature.com)
  • Long-term clinical prognosis of human infections with avian influenza A(H7N9) viruses in China after hospitalization. (ox.ac.uk)
  • Herein, we provide the latest update to the EASL Clinical Practice Guidelines on the use of non-invasive tests for the evaluation of liver disease severity and prognosis, focusing on the topics for which relevant evidence has been published in the last 5 years. (ucl.ac.uk)
  • Besides the characteristic clinical triad (ophthalmoplegia, ataxia, and areflexia), pupillary abnormalities, blepharoptosis, and facial palsy are frequent in MFS, whereas sensory loss is unusual despite the presence of profound ataxia. (neurology.org)
  • There is growing evidence that ischemic stroke is related to the systemic inflammatory response, and diverse inflammatory cytokines are being investigated as potential predictors of cardiovascular and functional prognosis after AIS [ 4 , 5 ]. (hindawi.com)
  • We recommend that clinical assessment include anorexia or reduced food intake, catabolic drive, muscle mass and strength, and functional and psychosocial impairment. (medpagetoday.com)
  • Thus, the integration of cDNA microarray, high-density tissue microarray, and linked clinical and pathology data is a powerful approach to molecular profiling of human cancer. (nature.com)
  • Molecular profiling of clinical tissue specimens: feasibility and applications. (nature.com)
  • By the from these conventional markers to determine individual same token, within the moderate/high-risk groups, pa- prognosis [6]. (lu.se)
  • The differences between the clinical characteristics and survival time in malignancy- and non-malignancy-associated secondary hemophagocytic lymphohistiocytosis (HLH) are unclear. (biomedcentral.com)
  • However, all these solutions cannot be currently implemented in the clinical routine because of the lack of effective means for monitoring allograft function and rational based approaches towards selection of the optimal immunosuppressive therapy. (europa.eu)
  • Practitioners should be aware of diverse clinical presentations and emphasize strict adherence to prophylaxis guidelines. (who.int)
  • Background: Based on the characteristics of systemic lupus erythematosus-associated pulmonary arterial hypertension (SLE-PAH), Sun et al has put forward a scoring system to distinguish two clinical phenotypes as vasculitic and vasculopathic subtypes[1]. (ashdin.com)