Clinical osteoporosis. Medical search. Frequent questions

The USPSTF found that the risk of serious adverse events, upper gastrointestinal events, or cardiovascular events associated with the most common class of osteoporosis medication (bisphosphonates) is no greater than small. (uspreventiveservicestaskforce.org)
Bisphosphonates have been widely used in the treatment of osteoporosis in women, whereas until now there have been few data on their use in men. (nih.gov)
Drug therapies for osteoporosis include bisphosphonates, such as alendronate and risedronate. (naturalmedicinejournal.com)
One main way osteoporosis is treated is via drugs called bisphosphonates, which in part inhibit osteoclasts. (ipscell.com)
Other studies have examined the risk of damage to jaw tissue with the use of bisphosphonates, one type of medication commonly used to treat osteoporosis. (harvard.edu)

Studies show that drug therapies reduce fractures in postmenopausal women with osteoporosis. (uspreventiveservicestaskforce.org)
Researchers, for example, found melatonin levels in postmenopausal women with osteoporosis were significantly lower than in young women with normal bone mass and suggested that melatonin levels could serve as an "auxiliary diagnostic index" for osteoporosis (Cao et al. (psychologytoday.com)
Over the course of 18 months, 80 postmenopausal women with osteoporosis received daily injections of either a placebo , a single unit of growth hormone or a 2.5-unit dose of growth hormone in the randomized, double-blind trial. (medicalnewstoday.com)

These include a sedentary lifestyle, lower body weight, family history of osteoporosis, smoking, and certain medications and diseases. (medscape.com)
Other factors that may affect the risk of fragility fracture include the use of oral or systemic glucocorticoids, age, sex, previous fractures and family history of osteoporosis. (nice.org.uk)
Important risk factors for male osteoporosis include a prior fragility fracture, glucocorticoid use or alcohol consumption, a family history of osteoporosis, and hypogonadism. (bcmj.org)

By 2022, it is estimated that 6.2 million Australians older than 50 years of age will have osteoporosis or osteopenia, a rise of 31% from 2012. (racgp.org.au)
A similar increase in the rate of fracture, from 140,882 in 2012 to 183,105 in 2022, is anticipated if action is not taken to improve the diagnosis and management of osteoporosis. (racgp.org.au)
Fast Five Quiz: Osteoporosis Myths vs Facts - Medscape - Aug 19, 2022. (medscape.com)

The authors concluded that multicomponent tools aimed at doctors and patients may support clinical decision making in the management of osteoporosis. (medscape.com)
To update the evidence-based position statement published by The North American Menopause Society (NAMS) in 2006 regarding the management of osteoporosis in postmenopausal women. (medscape.com)
Management of osteoporosis in postmenopausal women: 2010 position statement of The North American Menopause Society. (medscape.com)
Cite this: Management of Osteoporosis in Postmenopausal Women - Medscape - Mar 01, 2010. (medscape.com)

Thus, a questionable interpretation of data from patients with CKD and the subsequent extrapolation to healthy subjects converted a hypothesis into nutritional recommendations for the prevention of osteoporosis. (cambridge.org)
Osteoporosis prevention, diagnosis and management in postmenopausal women and men over 50 years of age, 2 nd edition was developed by Osteoporosis Australia and published by RACGP. (racgp.org.au)
Prevention of osteoporosis includes a proper diet during childhood, hormone replacement therapy for menopausal women, and efforts to avoid medications that increase the rate of bone loss. (wikipedia.org)
Efforts to prevent broken bones in those with osteoporosis include a good diet, exercise, and fall prevention. (wikipedia.org)
Osteoporosis prevention, diagnosis, and therapy. (medscape.com)
This often includes treatment with safe and effective PHARMAC funded treatments for osteoporosis and referral to local falls prevention services. (osteoporosis.org.nz)
Christine Gill, Executive Director of Osteoporosis New Zealand said, "The Clinical Standards were subject to a broad consultation process with learned societies and government agencies in New Zealand, and leading international organisations in the fragility fracture prevention arena. (osteoporosis.org.nz)
Osteoporosis affects mostly older women, but prevention starts when you are younger. (womenshealth.gov)
Pharmaceutical agents can be effective in treating osteoporosis, but there is an increased interest in non-pharmacological prevention and treatment for the condition. (naturalmedicinejournal.com)
The most important clinical determinant contributing to the clinical decision of initiating and choosing drug therapy for fracture prevention is a woman's fracture risk, which, in RCTs, was determined by menopausal state, age, bone mineral density, fracture history, fall risks and glucocorticoid use. (elsevierpure.com)
ProFatMRI's techniques contribute directly to EU policies for obesity prevention and osteoporosis screening, outlined within the European Commission's Health Promotion and Disease Prevention Knowledge Gateway . (europa.eu)
FOSAMAX is indicated for the treatment and prevention of osteoporosis in postmenopausal women. (merck.com)
The clinical preventive services discussed in this report are recommended for the prevention or early detection of heart disease and cancer. (cdc.gov)

The end result is that fewer Canadian women will be told to take osteoporosis medications. (betterbones.com)
This theory currently influences nutrition research, dietary recommendations and the marketing of alkaline salt products or medications meant to optimise bone health and prevent osteoporosis. (cambridge.org)
COVID-19 vaccines are safe and effective for patients taking osteoporosis medications, according to joint guidance from six endocrine and osteoporosis societies and foundations. (the-hospitalist.org)
Vaccination is happening worldwide, and we wanted to present a united front and united recommendations about how to handle osteoporosis medications appropriately during vaccination," said Suzanne Jan De Beur, MD , who is president of ASBMR and an associate professor of medicine at Johns Hopkins University, Baltimore. (the-hospitalist.org)
The guidance includes some recommendations for specific osteoporosis medications. (the-hospitalist.org)
Bisphosphonate medications are useful to decrease future broken bones in those with previous broken bones due to osteoporosis. (wikipedia.org)
A 2008 literature review suggested that the use of "reminders plus education targeted to physicians and patients" can lead to increased BMD testing and greater use of osteoporosis medications. (medscape.com)
Another common question is whether osteoporosis medications are harmful to your esophagus and the rest of your digestive tract. (harvard.edu)
That work proved essential for the development of medications to prevent osteoporosis , many of them initially tested in the Clinical Research Unit. (mayo.edu)
The development of DXA nearly coincided with the availability of effective osteoporosis medications. (biomedcentral.com)
Current osteoporosis medications increase bone density and reduce fracture risk but the mechanisms of these actions vary. (biomedcentral.com)
Up until the widespread use of DXA, patients at high fracture risk were not easily identified and effective osteoporosis medications were limited. (biomedcentral.com)

The publication of new data on the prevalence of osteoporosis in Australia and the health and economic impacts of this disease has also highlighted the need to clarify and re-enforce clinical guidance for health professionals at the front line of osteoporosis management. (racgp.org.au)
Because of increased bone loss after the menopause in women, and age-related bone loss in both women and men, the prevalence of osteoporosis increases markedly with age, from 2% at 50 years to more than 25% at 80 years in women. (nice.org.uk)

Osteoporosis, a condition associated with weak bones and an increased risk for fracture, is common in women after menopause. (medscape.com)
Around menopause, the decrease in estrogen levels results in an increase in RANKL and sclerostin, with a consequent increase in bone loss at a pace that exceeds the rate of bone formation, thereby leading to osteoporosis. (medscape.com)
With changes in hormonal levels, women after menopause are particularly vulnerable to developing osteopenia and ultimately full-blown osteoporosis (Munmum and Witt-Enderby. (psychologytoday.com)
It has even been suggested that plasma melatonin levels around menopause could be used as a "marker of potential susceptibility" for the development of osteoporosis after menopause or even as "prophylaxis" to treat women at risk (Sandyk et al. (psychologytoday.com)
Indicator excludes younger persons who are at risk for osteoporosis (e.g., as a result of steroid treatment or early menopause). (cdc.gov)
Quality control procedures for osteoporosis of the lumbar spinal of fracture) during menopause than were followed in accordance with the and the neck of the left femur. (who.int)
Clinical manifestations may include hot flushes, night sweats, sleep disruption, and genitourinary syndrome of menopause (symptoms and signs due to estrogen deficiency, such as vulvovaginal atrophy). (msdmanuals.com)
Major risk factors for postmenopausal osteoporosis (as defined by bone mineral density) include advanced age, genetics, lifestyle factors (such as low calcium and vitamin D intake, smoking), thinness, and menopause status. (medscape.com)

People of European and Asian background are most likely to get osteoporosis. (nyp.org)
And because people are living longer (and are therefore more likely to get osteoporosis), the cost of osteoporosis care is expected to rise to $25.3 billion by 2025. (harvard.edu)

This hypothesis posits that foods associated with an increased urinary acid excretion are deleterious for the skeleton, leading to osteoporosis and enhanced fragility fracture risk. (cambridge.org)
Osteoporosis leads to nearly 9 million fractures annually worldwide (Johnell and Kanis, 2006), and over 300,000 patients present with fragility fractures to hospitals in the UK each year ( British Geriatrics Society good practice guide on the care of patients with fragility fracture ). (nice.org.uk)
As the longevity of the population increases, so will the incidence of osteoporosis and fragility fracture. (nice.org.uk)
Today, Osteoporosis New Zealand has published new Clinical Standards for Fracture Liaison Services that underpin a nationwide strategy to prevent older Kiwis who sustain a fragility fracture from breaking other bones in the future. (osteoporosis.org.nz)
Participation in the New Zealand arm of a new Australian and New Zealand Fragility Fracture Registry will enable FLS teams to benchmark the care that they provide against the Clinical Standards in real time. (osteoporosis.org.nz)
The World Health Organization (WHO) defines osteoporosis as a BMD T-score of − 2.5 or lower at any one location or having a previous fragility fracture. (biomedcentral.com)

The USPSTF found adequate evidence that clinical risk assessment tools are moderately accurate in identifying risk of osteoporosis and osteoporotic fractures. (uspreventiveservicestaskforce.org)
The USPSTF found adequate evidence that screening can detect osteoporosis and that treatment provides a moderate benefit in preventing fractures in postmenopausal women younger than age 65 years who are at increased risk of osteoporosis. (uspreventiveservicestaskforce.org)
Risk of osteoporosis is also directly linked to the use of many prescription and over-the-counter drugs: corticosteroids/steroids, thyroid hormones, anticonvulsants, aluminum containing antacids (ironically, often recommended as a calcium source by mainstream physicians), loop diuretics, gonadotropin-releasing hormones, and many others. (naturalmedicinejournal.com)
Most experts recommend that the decision to test younger women be made on an individual basis, depending on the risk of osteoporosis and whether the test results will help with treatment decisions. (healthwise.net)

Osteoporosis is a disease that causes bones to become brittle and more likely to fracture (break). (medlineplus.gov)
With osteoporosis, the bones lose density. (medlineplus.gov)
You have a bone fracture, and a bone density test shows you have thinner than normal bones, but not osteoporosis. (medlineplus.gov)
In those with osteoporosis but no previous broken bones, they are less effective. (wikipedia.org)
Osteoporosis is a disease of the bones that causes bones to become weak and break easily. (womenshealth.gov)
Broken bones from osteoporosis cause serious health problems and disability in older women. (womenshealth.gov)
Osteoporosis is a disease of the bones. (womenshealth.gov)
People with osteoporosis have bones that are weak and break easily. (womenshealth.gov)
The term osteoporosis describes a condition inside the bones in which large porous areas develop, weakening the bone structure. (naturalmedicinejournal.com)
Osteoporosis is a progressive condition in which bones become weak and liable to fracture. (medicalnewstoday.com)
If you are at increased risk for broken bones caused by osteoporosis, routine testing should start sooner. (healthwise.net)
Osteoporosis is a disease that affects your bones . (nyp.org)
Osteoporosis can lead to broken bones (fractures) in the hip, spine, wrist, and other parts of your body. (nyp.org)
Some people are more predisposed to osteoporosis, particularly those who are petite or have small bones to start with in life. (ipscell.com)
Conversely, too much osteoclast activity could lead to thin bones, which in a sense may be what's happening in some forms of osteoporosis, possibly as a result of hormonal changes. (ipscell.com)
One of those diseases is osteoporosis, a thinning and weakening of the bones, which means they break more easily. (harvard.edu)
Osteoporosis [1] is a bone disease characterized by bone density loss to the point that bones become weak and brittle, making bone fractures more likely. (healthcanal.com)
Here are the top 10 superfoods for strong bones that contain calcium and vitamin D to help your bones continue to regenerate and fight off osteoporosis. (healthcanal.com)

Additionally, implementation could promote overuse of screening if patients receive care from multiple physicians and/or have poor record continuity, and in women who are at lower risk for osteoporosis based on reasonably identifiable factors (e.g. (acponline.org)
The clinical impact of vertebral fractures: quality of life in women with osteoporosis. (orthobullets.com)
Unfortunately, severe osteoporosis can force women to relinquish even these social roles, leaving them with no source of self-esteem or accomplishment. (orthobullets.com)
The USPSTF found convincing evidence that screening can detect osteoporosis and that treatment of women with osteoporosis can provide at least a moderate benefit in preventing fractures in women age 65 years and older. (uspreventiveservicestaskforce.org)
The USPSTF found no studies that described harms of screening for osteoporosis in men or women. (uspreventiveservicestaskforce.org)
The USPSTF concludes with moderate certainty that the net benefit of screening for osteoporosis in women age 65 years and older is at least moderate. (uspreventiveservicestaskforce.org)
The National Health and Nutrition Examination Survey from 2013 to 2014 reported that 16.5 % of women aged 50 years or older in the US have osteoporosis (vs only 5% of men of a similar age), with an increasing prevalence with increasing age. (medscape.com)
For example, the risk for osteoporosis of the hip increases from about 7% in women 50-59 years of age to about 35% in those aged 80 years or older . (medscape.com)
About 22 million women and 5.5 million men in the European Union had osteoporosis in 2010. (wikipedia.org)
In the United States in 2010, about 8 million women and between 1 and 2 million men had osteoporosis. (wikipedia.org)
Close clinical surveillance of all women taking estrogens is important. (nih.gov)
A clinical practice guideline from the American College of Physicians on treatment to prevent fractures in men and women with low bone density or osteoporosis includes six recommendations: two strong recommendations, based on high- or moderate-quality evidence, and four weak ones, based on low-quality evidence. (medscape.com)
In postmenopausal women, estrogen or estrogen plus progestogen or raloxifene should not be used for the treatment of osteoporosis. (medscape.com)
Monitoring of bone mineral density (BMD) during the 5 years of treatment in women with osteoporosis is not advised, as evidence suggests that fracture risk may be reduced regardless of BMD changes. (medscape.com)
Osteoporosis affects more women than men. (womenshealth.gov)
Of the estimated 10 million Americans with osteoporosis, more than 8 million (or 80%) are women. (womenshealth.gov)
Osteoporosis is most common in older women. (womenshealth.gov)
In the United States, osteoporosis affects one in four women 65 or older. (womenshealth.gov)
4 But younger women can get osteoporosis. (womenshealth.gov)
Are some women more at risk for osteoporosis? (womenshealth.gov)
One in four Mexican-American women and about one in six white women over 50 years old have osteoporosis. (womenshealth.gov)
6 Asian-American women also have a higher risk for osteoporosis because they are usually smaller and thinner than other women and therefore may have less bone density. (womenshealth.gov)
Osteoporosis may result in considerable morbidity and even mortality in both men and women. (psychologytoday.com)
June 12, 2006 (Atlanta) - Women with breast cancer who are treated with the aromatase inhibitor anastrozole ( Arimidex , AstraZeneca) for 5 years can lose 6% to 7% in bone-mineral density (BMD), enough to trigger a progression to osteoporosis in those who are already osteopenic when treatment begins, according to a group of investigators that reported these findings here at the 42nd annual meeting of the American Society of Clinical Oncology. (medscape.com)
For women with normal BMD at baseline, however, taking anastrozole for 5 years is unlikely to cause osteoporosis, said principal investigator Robert E. Coleman, MD, in a briefing. (medscape.com)
It was interesting that women with a normal BMD at baseline did not develop osteoporosis," said Stephen Y. Chui, MD, who was not involved in the study. (medscape.com)
Several risk factors increase the chance of developing osteoporosis: family history, gender (women are 6 to 8 times more likely than men), being postmenopausal, advanced age, race (Caucasians are the most likely), low calcium intake, smoking, alcohol consumption, a sedentary lifestyle, 4 and soft drink consumption. (naturalmedicinejournal.com)
Growth hormone treatment has sustained effects against problems associated with osteoporosis for years after it is stopped in postmenopausal women, suggests a new trial. (medicalnewstoday.com)
The researchers compared the participants' bone density and rate of fractures with those of a group of 120 women who did not have osteoporosis. (medicalnewstoday.com)
In contrast, the rate of fractures rose four-fold in the control group as some of those women were diagnosed with osteoporosis. (medicalnewstoday.com)
Osteoporosis affects one in three women, but men are also concerned. (theconversation.com)
Objectives: This study aims to identify the frequency of clinical risk factors associated with osteoporosis in postmenopausal women. (sdu.edu.tr)
Women with secondary osteoporosis were excluded, except in studies of glucocorticoid use. (elsevierpure.com)
Aim: the purpose of this study was to characterise postmenopausal women attending osteoporosis centres in Italy, to evaluate physician management, and to determine the incidence of first osteoporotic fracture. (unito.it)
Data were collected from women attending osteoporosis centres. (unito.it)
Women without prevalent fracture were eligible to enter the 1-year follow-up phase: the clinical approach to patients according to their fracture risk profile and the incidence of fracture were recorded. (unito.it)
Conclusions: in a large, unselected sample of postmenopausal women attending osteoporosis centres, those without previous fracture were at substantial risk of future fracture, regardless of their theoretical low 10-year fracture risk. (unito.it)
The U.S. Preventive Services Task Force (USPSTF) recommends that all women age 65 and older routinely have a bone density test to check for osteoporosis. (healthwise.net)
Osteoporosis is a well-recognized problem in older women. (bcmj.org)
Although both the 1-year mortality and the need for institutional care after a hip fracture are higher in men than women, men are less likely to receive investigation or treatment for their underlying osteoporosis. (bcmj.org)
Using the normal, young male value, 3% to 6% of men over 50 have osteoporosis, compared with a 22% gender-specific prevalence in women. (bcmj.org)
Osteoporosis is most common in older people, especially (but not only) in women. (harvard.edu)
Despite the availability of cost-effective and well-tolerated treatments that can reduce fracture risk, only 23% of women ages 67 or older who have an osteoporosis-related fracture receive either a bone mineral density test or a prescription for an osteoporosis drug in the six months after the fracture. (harvard.edu)
Why are so many people, especially women, not receiving osteoporosis treatment? (harvard.edu)
Because osteoporosis is a silent disease until a fracture occurs, women often question the need for treatment at all. (harvard.edu)
ABSTRACT To test the hypothesis that regional fat and not total body weight has a protective effect on bone mineral density (BMD) in postmenopausal women, a cross-sectional study was conducted during the period from March 2008 to June 2009 on 303 healthy postmenopausal women presenting to the osteoporosis unit for screening purposes. (who.int)
With increasing life expectancy, osteoporosis is becoming a major worldwide health problem affecting the elderly, especially women. (who.int)
Barrett-Connor E, Siris ES, Wehren LE et al (2005) Osteoporosis and fracture risk in women of different ethnic groups. (springer.com)
Later, Dr. Khosla found that estrogen, the hormone that regulates female bone metabolism, regulates bone metabolism in men as well, and that declining estrogen levels can lead to osteoporosis in aging men just as in postmenopausal women. (mayo.edu)
More than half of postmenopausal, White women will experience an osteoporosis-related fracture, and with the aging United States population, the number of these fractures is expected to triple . (medscape.com)
Osteoporosis, which is especially prevalent among older postmenopausal women, increases the risk of fractures. (medscape.com)
The evaluation of postmenopausal women for osteoporosis risk requires a medical history, physical examination, and diagnostic tests. (medscape.com)
DESCRIPTION: This guideline updates the 2008 American College of Physicians (ACP) recommendations on treatment of low bone density and osteoporosis to prevent fractures in men and women. (bvsalud.org)

Raloxifene (Evista) may also be used to prevent and treat osteoporosis. (medlineplus.gov)
Other selective estrogen receptor modulators (SERMs) are also used to treat osteoporosis. (medlineplus.gov)
Healthcare providers can help prevent and treat osteoporosis by supporting the improvement of nutritional status through diet and nutritional supplementation, along with suggestion for an increase in exercise training. (naturalmedicinejournal.com)

2 , 4 The prevalence of primary osteoporosis (i.e., osteoporosis without underlying disease) increases with age and differs by race/ethnicity. (uspreventiveservicestaskforce.org)
The aim of this study was to evaluate the effect of a 3-year alendronate treatment on bone mineral density (BMD) and quantitative ultrasound (QUS) in men with primary osteoporosis. (nih.gov)
In genetic forms of primary osteoporosis, such as Osteogenesis imperfecta, additional exam findings can include characteristic facial features, blue sclerae, dentinogenesis imperfecta, and hypermobility. (medscape.com)

Guidance signatories include ASBMR, the American Association of Clinical Endocrinology, the Endocrine Society, the European Calcified Tissue Society, the National Osteoporosis Foundation, and the International Osteoporosis Foundation. (the-hospitalist.org)
Currently, FLS across New Zealand are working towards delivering a world-class service in accordance with the International Osteoporosis Foundation Capture the Fracture® Best Practice Framework. (osteoporosis.org.nz)

While several bone measurement tests similarly predict risk of fracture, DXA directly measures bone mineral density (BMD), and most treatment guidelines use central DXA to define osteoporosis and the treatment threshold to prevent osteoporotic fractures. (uspreventiveservicestaskforce.org)
The joint guidance - released by the American Society for Bone and Mineral Research (ASBMR), the American Association of Clinical Endocrinologists, the Endocrine Society, the European Calcified Tissue Society, and the National Osteoporosis Foundation - offered both general and specific recommendations for patients whose osteoporosis treatment plan is either continuing or has been disrupted during the COVID-19 pandemic. (the-hospitalist.org)
For all patients whose treatments have been disrupted, the authors recommend frequent reevaluation "with the goal to resume the original osteoporosis treatment plan once circumstances allow. (the-hospitalist.org)
There was a dearth of information about the best practices for osteoporosis treatment management during vaccination, and we didn't want people missing their opportunity for a vaccine, and we also didn't want them unnecessarily delaying their osteoporosis treatment. (the-hospitalist.org)
Nancy E. Lane, MD, shares her take on updated guidelines on fracture risk groups and treatment recommendations for primary and secondary osteoporosis. (clinicaloptions.com)
If you are a healthcare professional, you should rely on your professional judgment in evaluating any and all information and confirm the information contained on the Clinical Education Alliance Sites with other sources and reliable third parties before basing any treatment or advice on it. (clinicaloptions.com)
Before embracing the procedure as a routine treatment, the immediate loading technique needs to be validated with a significant number of clinical cases, extended follow-ups, and a clear definition of limitations. (allenpress.com)
A 2009 study indicated that the use of a case manager for the treatment of patients with hip fractures can lead to more frequent use of appropriate osteoporosis treatment and may result in fewer fractures, increased life expectancy, and significant health-care cost savings. (medscape.com)
Currently, no treatment can completely reverse established osteoporosis. (medscape.com)
If secondary osteoporosis is present, treatment for the primary disorder should be provided. (medscape.com)
Therapy should be individualized based on each patient's clinical scenario, with the risks and benefits of treatment discussed between the clinician and patient. (medscape.com)
This hormone may have a role in the treatment of osteoporosis. (psychologytoday.com)
The authors of the study believe it is the largest and longest controlled study with growth hormone treatment in postmenopausal osteoporosis . (medicalnewstoday.com)
Effect of growth hormone treatment on fractures and quality of life in postmenopausal osteoporosis: a 10-year follow-up study Emily Krantz et al. (medicalnewstoday.com)
There is no treatment for osteoporosis, which affects millions of people and costs billions of euros every year. (theconversation.com)
Have the DXA test to find out whether you need treatment for osteoporosis. (nyp.org)
The results of the test may show that you need treatment for osteoporosis. (nyp.org)
Some clinical work popped up but it was mainly related to bone marrow loss after hematopoietic stem cell transplantation such as during treatment for blood cancers. (ipscell.com)
It is hoped that a greater awareness of the problem of osteoporosis in men will lead to better treatment, and ultimately to a de-crease in fractures and their associated morbidity and mortality. (bcmj.org)
Why not more treatment for osteoporosis? (harvard.edu)
In a series of clinical studies, researchers in the Clinical Research Unit found answers that revolutionized diabetes treatment. (mayo.edu)
To provide updated evidence-based recommendations for the treatment of postmenopausal osteoporosis. (bvsalud.org)

This model at the skeletal level following spinal cord injury resembles the high bone turnover rate seen in postmenopausal osteoporosis. (medscape.com)
Osteoporosis is a systemic skeletal disorder characterized by low bone mass, micro-architectural deterioration of bone tissue leading to bone sterility, and consequent increase in fracture risk. (wikipedia.org)
The clinical challenge remains in identifying those children with skeletal pathology associated with their fracture. (medscape.com)
Taken together, a history of axial skeletal fractures or multiple fractures from low biomechanical force may be indicators of skeletal fragility and should raise concern for osteoporosis. (medscape.com)
Osteoporosis (OP) is a skeletal disease characterized by low bone mass and microarchitectural deterioration of bone tissue, leading to increased susceptibility to fractures (World Health Organization, 1994). (unm.edu)
Osteoporosis is a disease of the skeletal system that is characterized by deterioration of bone tissue, along with a decrease in bone mass. (naturalmedicinejournal.com)
This review retreats to basic principles in order to advance clinical management of fragility fractures by examining how skeletal biomechanics, size, shape, and ultra-structural properties are the ultimate predictors of bone strength. (biomedcentral.com)

The U.S. Preventive Services Task Force (USPSTF) makes recommendations about the effectiveness of specific clinical preventive services for patients without obvious related signs or symptoms. (uspreventiveservicestaskforce.org)
Five leading bone health organizations have gotten together to provide new recommendations for managing patients with osteoporosis during the COVID-19 pandemic. (the-hospitalist.org)
As we continue to care for our patients, we need to keep chronic conditions like osteoporosis on the radar screen and not stop diagnosing people at risk or those who present with fractures. (the-hospitalist.org)
Osteoporosis itself does not appear associated with increased risk of infection or severe outcomes, so patients with osteoporosis do not need to be prioritized for vaccination based on that condition alone. (the-hospitalist.org)
There is no evidence that osteoporosis therapies affect the safety or efficacy of vaccination, but given that vaccine availability is currently inconsistent, patients may need to make temporary changes to their osteoporosis regimens to ensure they can receive vaccine when it is available, such as ensuring a delay between medication and vaccination injections. (the-hospitalist.org)
For patients with established osteoporosis, medical intervention can halt its progression. (medscape.com)
Patients identified as at risk for osteoporosis (including children and adolescents) should undergo preventive measures, including adequate calcium intake, vitamin D intake, and exercise. (medscape.com)
Five patients with osteopenia at baseline developed osteoporosis by the end of the follow-up period, he said. (medscape.com)
They are also translating their bone and bone marrow imaging techniques into clinical spine examinations, especially to assess fracture in patients with degenerative spine changes and bone metastases. (europa.eu)
There has been debate about whether the bone density of male patients should be compared with that of normal young males (gender-specific) or with that of normal females, which results in different T-scores (0.5 to 1.0 SD units lower when normal male data are used) and therefore different frequencies of "osteoporosis" (defined as a T-score less than 22.5). (bcmj.org)
And the patients are actually research volunteers participating in clinical studies. (mayo.edu)
The company's clinical trials, conducted both before and following approval, have involved more than 28,000 patients, including more than 17,000 treated with FOSAMAX. (merck.com)
This incongruity poses a challenge to clinicians to identify patients who may benefit from osteoporosis treatments. (biomedcentral.com)
In practice, however, a compatible donor can be found for less than 30% of patients, and the success rate of the intervention depends on their age and the quality of clinical management they have received throughout their lives. (who.int)
In recent years, a vibration-based bone shock absorption (BSA) method has shown potential to relate the damping capacity associated with the fundamental (first) vibration modes for developing dynamic bone quality indicators for osteoporosis patients. (cdc.gov)
The damping ratio corresponding to few vibration modes is extracted and analyzed using clinical bone shock absorption data of patients with different Pb exposure levels. (cdc.gov)

Osteopenia and osteoporosis, diagnosed by degrees of low bone mass and bone tissue deterioration, lead to substantial morbidity and mortality. (psychologytoday.com)
Projections indicate that by 2030, without intervention, 64.3 million Americans will develop osteopenia and 11.9 million will have osteoporosis (Lu et al. (psychologytoday.com)

The primary cause of postmenopausal osteoporosis is the cessation of estrogen production by the ovaries around the menopausal transition. (medscape.com)

The DXA test measures bone thickness to find out if you have osteoporosis or if you are at risk for a broken bone (fracture). (nyp.org)

Tsai AJ (2019) Disparities in osteoporosis by race/ethnicity, education, work status, immigrant status, and economic status in the United States. (springer.com)

Recent changes to Osteoporosis Canada's 2010 Clinical Practice Guidelines mean that deciding who needs a bone medication will now depend on a multi-factorial fracture risk assessment, rather than on simple bone density testing. (betterbones.com)
On a scale of 1 to 10, rate how much this article will change your clinical practice? (orthobullets.com)
Nature Clinical Practice Rheumatology , 4 (5), 240-248. (elsevierpure.com)
Because osteoporosis is a chronic disease, years might pass before changes in patient behavior or clinical practice affect hospitalization for hip fracture. (cdc.gov)
This guideline was developed using an a priori protocol in conjunction with a writing team consisting of two specialists in obstetrics and gynecology appointed by the ACOG Committee on Clinical Practice Gu. (bvsalud.org)

This performance measure will likely result in meaningful and measurable improvements in clinical outcomes and aligns with United States Preventive Services Task Force (USPSTF) recommendations on screening for osteoporosis. (acponline.org)
The USPSTF found no studies that evaluated the effect of screening for osteoporosis on fracture rates or fracture-related morbidity or mortality. (uspreventiveservicestaskforce.org)
Screening for osteoporosis is usually safe and painless. (medicalnewstoday.com)
2018). Screening for osteoporosis to prevent fractures: U.S. Preventive Services Task Force recommendation statement. (healthwise.net)
Despite the medical and economic costs of fragility fractures, osteoporosis screening is often overlooked and viewed as a low priority. (biomedcentral.com)
Bone mass measurement, fracture risk, and screening for osteoporosis. (cdc.gov)

Similarly, the USPSTF notes that policy and coverage decisions involve considerations in addition to the evidence of clinical benefits and harms. (uspreventiveservicestaskforce.org)
The USPSTF found inadequate evidence on the benefits and harms of treating screen-detected osteoporosis to reduce the risk of osteoporotic fractures in men. (uspreventiveservicestaskforce.org)
Despite these limitations, we have learned quite a lot about the benefits and harms of osteoporosis treatments. (harvard.edu)

Saraff V, Högler W. ENDOCRINOLOGY AND ADOLESCENCE: Osteoporosis in children: diagnosis and management. (medscape.com)

Vertebral Fractures: Which Radiological Criteria Are Better Associated With the Clinical Course of Osteoporosis? (bvsalud.org)

In this CPD accredited report, six case studies focusing on the diagnostic skills needed to diagnose unusual causes of osteoporosis are presented. (denovomedica.com)
The traditional diagnostic biomarker for osteoporosis is bone mineral density (BMD). (europa.eu)

The statement also provides potential alternative methods for delivering parenteral osteoporosis treatments, including off-site clinics, home delivery and administration, self-injection of denosumab and/or romosozumab, and drive-through administration of denosumab and/or romosozumab. (the-hospitalist.org)

Harms of drug therapies for osteoporosis depend on the specific medication used. (uspreventiveservicestaskforce.org)

But our real understanding of osteoporosis stems from research undertaken over the last 75 years, and principally since 1990, when we have developed a uniform definition of osteoporosis based on bone density measurement, developed a number of antiresorptive and formation stimulating therapies against osteoporosis, and developed coherent risk assessment strategies. (hstalks.com)
The step change for this was the WHO definition of osteoporosis, which is shown in this next slide, that was coined in 1994 and characterized osteoporotic bone density as 2.5 standard deviations or more below the young normal mean. (hstalks.com)
There is less consensus of the definition of osteoporosis in men. (biomedcentral.com)

In June, Medical News Today reported on a study in which researchers discovered a way to boost bone-forming cells , paving the way for new treatments for osteoporosis. (medicalnewstoday.com)

One of the inevitable complications of spinal cord injury (SCI) is the associated osteoporosis that occurs predominantly in the pelvis and the lower extremities (see the image below). (medscape.com)
Osteoporosis in persons with spinal cord injury was first studied in relation to calcium metabolism and the associated hypercalcemia and renal calculi that followed. (medscape.com)
The differences between osteoporosis induced by spinal cord injury and other causes of bone loss (disuse), such as prolonged bed rest, space travel, and lower motor neuron disorders, have since become clearer. (medscape.com)
A longitudinal cohort study by Rodriguez et al found the 4-year incidence of musculoskeletal morbidities (such as osteoporosis, sarcopenia, osteoarthritis, and fractures) to be 82.4% in adults with traumatic spinal cord injury, compared with 47.5% in adults without such injury. (medscape.com)
The mechanism behind spinal cord injury (SCI)-induced osteoporosis is accepted as being multifactorial in the acute and chronic stages. (medscape.com)
[ 11 ] These other factors further separate spinal cord injury-induced osteoporosis from other causes of disuse demineralization. (medscape.com)
The body that has sustained spinal cord injury has been considered the model of premature aging, and the role of parathyroid hormone (PTH) in osteoporosis following spinal cord injury illustrates this point. (medscape.com)

There is no evidence that any osteoporosis therapy increases the risk or severity of COVID-19 infection or alters the disease course," they wrote. (the-hospitalist.org)
More than 10 million Americans are afflicted, and 34 million more may already be exhibiting signs of low bone mass, which increases the risk of developing osteoporosis. (naturalmedicinejournal.com)
Low bone mass increases the risk of developing osteoporosis and fractures. (naturalmedicinejournal.com)

In conclusion, this study confirms that alendronate represents an important therapeutic advance in the management of male osteoporosis. (nih.gov)

Early intervention can prevent osteoporosis in most people. (medscape.com)

The FRAX tool can help predict your risk of having a fracture related to osteoporosis in the next 10 years. (healthwise.net)

A burden of disease analysis recently published by Osteoporosis Australia estimates that in 2012, 4.74 million Australians older than 50 years of age (66%) had poor bone health, including more than one million with osteoporosis. (racgp.org.au)
Osteoporosis is a major public health issue affecting more than 10 million Americans. (naturalmedicinejournal.com)
Osteoporosis is recognized as a major public health issue. (naturalmedicinejournal.com)
Despite metabolic syndrome and osteoporosis being of major global health and socio-economic concern, patient management for both remains problematic. (europa.eu)
Given the health implications of osteoporotic fractures, the primary goal of osteoporosis therapy is to prevent fractures, which is accomplished by slowing or stopping bone loss, maintaining bone strength, and minimizing or eliminating factors that may contribute to fractures. (medscape.com)
Large parts are located in Malmö at the Clinical Research Centre (CRC), a modern and award-winning building for research, education, health and medical care. (lu.se)

Osteoporotic fractures are defined as fractures associated with low bone mineral density (BMD) and include clinical spine, forearm, hip and shoulder fractures. (nice.org.uk)
Osteoporosis can affect any bone in the body, although the most common sites are the wrist, spine, and hips. (naturalmedicinejournal.com)
The collected data were coded, Recent studies have shown that the lumbar spine (L2-L4) in the an- tabulated, revised and statistically ana- obesity and osteoporosis share several teroposterior position, and the proximal lysed using SPSS , version 17. (who.int)

Recent studies have shown that obesity and osteoporosis share several common genetic and environmental factors [2]. (who.int)

The 4-year incidence of osteoporosis in the two groups was 24.0% and 6.2%, respectively. (medscape.com)

Two million osteoporosis fractures occur in the U.S. each year costing approximately $19 billion [ 1 ]. (biomedcentral.com)

At the same time, careful clinical management greatly improves thalassaemics' quality of life and increases their life expectancy. (who.int)

Background: Osteoporosis is a highly prevalent disease and fractures are a major cause of disability and morbidity. (unito.it)

We used data from both sexes in the Canadian Multicentre Osteoporosis Study (CaMos) to compare the 2 methods in identifying OVF at baseline and during 10 years of follow-up. (bvsalud.org)

The fourth case is an elderly patient with HIV on antiretroviral therapy with chronic kidney disease (CKD), diabetes, Gastroesophageal reflux disease (GORD), depression and severe osteoporosis. (denovomedica.com)
Some haemoglobinopathy genes ( alpha-thal, beta-thal and HbS ) cause alpha-thalassaemia, beta-thalassaemia and sickle-cell anaemia, respectively, but others ( HbE and HbC ) cause severe clinical manifestations of the disease only when combined with one of the former genes. (who.int)

However, older thalassaemics may have to contend with multiple conditions including early osteoporosis, cardiac disease, pulmonary hypertension and diabetes, some of which result from increased iron deposition in the endocrine glands and myocardial cells. (who.int)

Osteoporosis may be due to lower-than-normal maximum bone mass and greater-than-normal bone loss. (wikipedia.org)
If your body doesn't have the nutrients to keep up with the bone loss by creating new bone, you may experience osteoporosis like millions of other people. (healthcanal.com)

Separately, in a letter to the editor published in the Journal of Clinical Endocrinology and Metabolism ( doi: 10.1210/clinem/dgaa254 ), Ruban Dhaliwal, MD , MPH, of the State University of New York, Syracuse, and coauthors concur in regard to raloxifene. (the-hospitalist.org)
The results are published in The Journal of Clinical Endocrinology & Metabolism . (medicalnewstoday.com)

Anatomy16

Diseases25

Chemicals and Drugs28

Analytical, Diagnostic and Therapeutic Techniques and Equipment14

Phenomena and Processes9

Technology, Industry, Agriculture1

Information Science2

Named Groups1

Health Care10

Bisphosphonates5

Postmenopausal women with osteoporosis3

Family history of osteoporosis3

20223

Management of osteoporosis4

Prevention13

Medications12

Prevalence of osteoporosis2

Menopause8

Likely to get osteoporosis2

Fragility fracture6

Risk of osteoporosis4

Bones18

Women53

Treat osteoporosis3

Primary osteoporosis3

International Osteoporosis Foundation2

Treatment22

Skeletal7

Patients16

Osteopenia2

Estrogen1

Test measures bone thickness1

20191

Practice5

Screening6

Benefits and harms3

Diagnosis and management1

Vertebral fractures1

Diagnostic2

Denosumab1

Therapies for osteoporosis1

Definition of osteoporosis3

Treatments for osteoporosis1

Spinal7

Increases the risk3

Male osteoporosis1

Prevent osteoporosis1

Fracture-related1

Health6

Spine3

Obesity1

Incidence1

Fractures occur1

Life expectancy1

Prevalent1

CaMos1

Severe2

Diabetes1

Bone loss2

Endocrinology2