• Outcomes
  • Checkpoint blockade therapy for cancer has had tremendous impact on clinical outcomes, yet only a subset of patients respond. (labroots.com)
  • General clinical features were comparable to western patients, while therapeutic outcomes were slightly inferior. (medworm.com)
  • In recent years, increased ease and reduced costs of characterizing the composition of the microbiome has led to an examination of its impact on a variety of clinical outcomes. (medworm.com)
  • It provides an international standard for oncologists and pathologists for use in the design of studies monitoring response to therapy and clinical outcomes. (wikipedia.org)
  • cancers
  • Rather than inhibiting kinase activity, elimination of mutant kinases provides a new therapeutic strategy for treating BCR-ABL-induced leukemia as well as other cancers resistant to treatment with tyrosine kinase inhibitors. (bloodjournal.org)
  • refractory
  • Treatment alternatives are limited for patients that are relapse after or refractory to induction regimens for acute leukemia. (medworm.com)
  • But treatment of leukemia patients refractory after FLAG salvage regimen are very diffucult and complete remission rates are very low. (medworm.com)
  • Diagnosis
  • The conclusive diagnosis of any of the chronic leukemias requires a skilled morphologist, but early consideration of these disorders and prompt referral can result not only in more efficient patient management, but also in considerable cost savings to the laboratory and hospital. (thefreelibrary.com)
  • Once a diagnosis of a chronic leukemia is made, the laboratory supervisor, armed with knowledge of the disorders, can help guide decisions on the extent of laboratory testing to ensure that appropriate and cost-effective choices are made. (thefreelibrary.com)
  • A diagnosis of chronic leukemia may be first suspected in an older adult who is found to have an elevated white cell count but who is otherwise in good health. (thefreelibrary.com)
  • Much of the diagnosis of chronic leukemia is based on the morphologic examination of the peripheral blood smear. (thefreelibrary.com)
  • morphology
  • If the patient has leukemia, the morphology and immunophenotype check is needed to make sure the type of leukemia. (wikipedia.org)
  • Anemia can be classified in a variety of ways, based on the morphology of RBCs, underlying etiologic mechanisms, and discernible clinical spectra, to mention a few. (wikipedia.org)
  • incidence
  • The present study evaluated the incidence of cardiovascular events (CVEs) in 63 chronic myeloid leukemia (CML) patients after long-term exposure to nilotinib. (medworm.com)
  • Adults
  • T-PLL is a very rare leukemia, primarily affecting adults over the age of 30. (wikipedia.org)
  • However, about 90% of all leukemias are diagnosed in adults, with AML and CLL being most common in adults. (wikipedia.org)
  • Central nervous system (CNS) symptoms such cranial neuropathies due to meningeal infiltration are identified in less than 10% of adults and less than 5% of children, particularly mature B-cell ALL (Burkitt leukemia) at presentation. (wikipedia.org)