• A growing body of evidence suggests that CYP2C19 genotype-guided antiplatelet therapy improves patient outcomes following PCI. (medscape.com)
  • Clinical outcomes from the observational cohort included swollen and tender joint counts (28), physician global assessment, and the RA Clinical Disease Activity Index (CDAI). (springer.com)
  • There is some evidence that asthma education can improve health outcomes. (auckland.ac.nz)
  • Provide recommendations to inform future interventions to improve asthma outcomes in research and practice. (auckland.ac.nz)
  • Coexisting with anxiety/depression symptoms was an independent influencing factor of steroid resistance and IBD-related poor outcomes. (frontiersin.org)
  • But more recently, a growing number of studies have shown that anxiety or depression may increase the risk of poor disease outcomes such as relapse, hospitalization, and intestinal surgery ( 12 - 15 ). (frontiersin.org)
  • These organizational shifts have produced changes along a number of dimensions: increasing use of standardized clinical protocols and electronic medical records, more objective metrics for measuring clinical performance, payment models that put providers at risk for outcomes and a shift in physicians' perceptions of their own responsibility for cost. (bain.com)
  • Identification of disease risk factors and early markers will increase over time with emerging clinical outcomes 3 . (biorxiv.org)
  • Treatment is typically more effective in the early stages of disease, making early recognition important to achieving improved outcomes. (medscape.com)
  • Clinical trials provide guidance on likely treatment outcomes in these patients at risk. (jcadonline.com)
  • Prospective clinical trials and randomized controlled trials (RCTs) investigating antipsychotic dose reduction in schizophrenia were selected for systematic review and meta-analysis, respectively. (nih.gov)
  • Few original studies have described the prevalence and severity of clinical symptoms of primary ciliary dyskinesia (PCD). (ersjournals.com)
  • This systematic review and meta-analysis aimed to identify all published studies on clinical manifestations of PCD patients, and to describe their prevalence and severity stratified by age and sex. (ersjournals.com)
  • Even after taking into account the explanatory factors, the largest part of the between-studies variance in symptom prevalence remained unexplained for all symptoms. (ersjournals.com)
  • Three main factors--age, cognitive level, and type of language disorder--account for variability in the reported prevalence of epilepsy. (nih.gov)
  • Prevalence and risk factors for chronic bronchitis and farmer's lung in French dairy farmers. (bmj.com)
  • The prevalence of chronic bronchitis and of clinical farmer's lung was studied in 30 districts of the French Doubs province in relation to individual (age, sex, smoking) and geographical (altitude) factors. (bmj.com)
  • The main finding of this study is the highly significant increase of prevalence of the diseases in relation to altitude. (bmj.com)
  • Patients with active disease also had an increased prevalence of depression and anxiety compared with those in remission ( 3 , 6 ). (frontiersin.org)
  • 1 Although it appeared to be a rare disorder at that time, the prevalence of autism spectrum disorder (ASD) steadily increased. (aafp.org)
  • 3 , 4 The increase in ASD prevalence may be partially attributed to the evolving diagnostic criteria prior to the publication of Diagnostic and Statistical Manual of Mental Disorders , 5th ed. (aafp.org)
  • OBJECTIVE: To identify clinical factors associated with prevalence of fat atrophy (lipoatrophy) and fat accumulation (lipoaccumulation) in HIV-1 infected patients. (rti.org)
  • Although differences in state-specific prevalence estimates may reflect, in part, disparate age distributions, the sizes of the samples did not permit age adjustment of prevalence rates. (cdc.gov)
  • OBJECTIVE: An increased prevalence of atherosclerosis has been shown among patients with hypopituitarism. (lu.se)
  • In patients who received PCI after ACS (71% non-ST segment elevation ACS, 29% ST segment elevation MI) and were treated with clopidogrel, carriers of at least one *2 allele experienced a 1.5-fold increase in the risk of cardiovascular death, MI, and stroke in the subsequent year of follow up compared with noncarriers. (medscape.com)
  • We searched PubMed, Embase and Scopus for studies describing clinical symptoms of ≥10 patients with PCD. (ersjournals.com)
  • In many diseases it is known that symptoms evolve and change with age, but few studies describe PCD patients from different age groups and show how symptoms change over time. (ersjournals.com)
  • As a result, the number of patients suffering from what has been termed "long COVID" has significantly increased, and is now deemed a major social issue. (eurekalert.org)
  • In order to consider these questions, the research team developed a mathematical model that describes the process of persistent novel coronavirus infections within infected hosts as a non-linear simultaneous ordinary differential equation, and conducted simulated viral infection experiments on a computer using models whose parameters had been adjusted based on clinical data from patients diagnosed with the novel coronavirus. (eurekalert.org)
  • Aortic sclerosis, which is clinically defined as valve thickening without obstruction to outflow, is the most prevalent valve disease in developed countries, being present in about 25% of patients over age 65 years. (medscape.com)
  • Patients with severe calcific degenerative aortic stenosis can be categorized into three clinical groups at the time of diagnosis: those without evidence of congestive heart failure, those with chronic congestive heart failure, and those with acute heart failure requiring hospitalization. (medscape.com)
  • Practice nurses will frequently treat patients who have risk factors for fragility fracture. (nursinginpractice.com)
  • You can identify patients aged 50 and over who have a history of fragility fracture and work with a local fracture liaison service (FLS), where available, and impact on a reduction in fracture rates through secondary prevention programmes. (nursinginpractice.com)
  • Vertebral fracture identification is the most challenging issue for clinicians, with less than one third of patients with vertebral fracture coming to clinical attention. (nursinginpractice.com)
  • 9,10 A herpes zoster diagnosis has also been shown to slightly increase the risk of being diagnosed with cancer within the following year, and herpes zoster is up to 4 times more common in patients with hematologic malignancies. (clinicaladvisor.com)
  • In a matched model adjusted for clinical variables, the CCM was estimated to produce a 9.4% increase in the total percentage of adherent patients. (doaj.org)
  • Additionally, a statistically significant increase of 4.5% in the percentage of adherent patients treated with golimumab compared with etanercept and adalimumab was found.Conclusion: A CCM produced an important increase in the percentage of patients with rheumatoid arthritis adherent to treatment after 24 months of follow-up. (doaj.org)
  • A newly published meta-analysis of 9,192 patients also revealed that anxiety and depression were linked to a significantly increased probability of escalation of therapy and emergency department attendance ( 16 ). (frontiersin.org)
  • The clinical course of COVID-19 is variable, with clinical manifestation ranging from 81% mild course to 14% severe course along with 5% critical course in patients. (tubitak.gov.tr)
  • Because of this, there was generally not much information available regarding the clinical details and frequency of readmissions for peritoneal dialysis patients, she explained. (medpagetoday.com)
  • This cohort included peritoneal dialysis patients over the age of 18. (medpagetoday.com)
  • These results, together with our finding of lower readmission risk among patients admitted for peritonitis -- which would likely be closely monitored in the post-discharge period -- suggests that there are missed opportunities for improving care transitions at hospital discharge in this population," she concluded. (medpagetoday.com)
  • The dental profession is committed to delivering the highest quality of care to each of its individual patients and applying advancements in technology and science to continually improve the oral health status of the U.S. population. (fda.gov)
  • A study of 490 patients found that basing selection criteria on clinical evaluations for asymptomatic patients, combined with selected periapical radiographs for symptomatic patients, can result in a 43 percent reduction in the number of radiographs taken without a clinically consequential increase in the rate of undiagnosed disease. (fda.gov)
  • 23 patients (14 female, ages 21-77 years), presented with acute thrombocytopenia and thrombosis 6 to 24 days after ChAdOx1 nCoV-19 vaccination. (cdc.gov)
  • Antibodies to platelet factor 4 (PF4) were positive in 22 patients and negative in 1 patient. (cdc.gov)
  • Patients are primarily older than age 60 years. (medscape.com)
  • There are increasing evidences that show that the prognosis of patients with acute ischemic stroke (AIS) is closely related to the inflammatory response. (hindawi.com)
  • The company's clinical trials, conducted both before and following approval, have involved more than 28,000 patients, including more than 17,000 treated with FOSAMAX. (merck.com)
  • RESULTS: Independent factors for moderate/severe lipoatrophy for 171 patients were increasing age, any use of stavudine, use of indinavir for longer than 2 years, body mass index (BMI) loss, and measures of duration and severity of HIV disease. (rti.org)
  • Independent risk factors for moderate/severe fat accumulation for 104 patients were increasing age, BMI gain, measures of amount and duration of immune recovery, and duration of antiretroviral therapy (ART). (rti.org)
  • Patients were divided into 2 age groups: younger than 50 years and 50 years or older. (cdc.gov)
  • We used widely available statewide hospitalization data to identify and test the joint predictive power of clinical risk factors associated with death by suicide for patients previously hospitalized for a suicide attempt (N = 19,057). (nature.com)
  • In addition, follow-up of patients completing suicide risk assessments have found that predictive models applied to EHR data achieved higher sensitivity and specificity in identifying suicidal behavior than clinical assessments 15 . (nature.com)
  • Similar findings were observed in a study utilizing veterans' health data, providing additional evidence that, while clinicians may identify a state of risk using traditional clinical assessment techniques, predictive models are capable of identifying higher-risk patients who are missed during clinical assessments and are most likely to complete a lethal suicidal act 4 , 16 . (nature.com)
  • Despite the promise of using large healthcare databases to identify patients at risk of suicide, a critical challenge still remains: how to incorporate such models into clinical practice in diverse healthcare settings. (nature.com)
  • Because the women did not change their antidepressant medications or other environmental factors that relate to depression, the authors concluded that correction of the patients' underlying shortage of vitamin D might be responsible for the beneficial effect on depression. (sciencedaily.com)
  • Patients infected with the virus SARS-CoV-2 and its clinical disease COVID-19 are often minimally symptomatic or asymptomatic. (scialert.net)
  • More research is needed in onychomycosis patients with these important risk factors and comorbidities to fully evaluate the treatment challengse and possible solutions. (jcadonline.com)
  • However, some comorbid conditions (i.e., peripheral vascular disease) can be exclusion criteria, many trials were not set up to specifically study certain comorbidities, and the demographics and disposition of patients who visit dermatology and podiatry practices can be very different from those enrolled in clinical trials. (jcadonline.com)
  • The aim of the present study was to assess whether patients with hypopituitarism experience increased cardiovascular, in particular cerebrovascular, mortality. (lu.se)
  • The factors responsible for response to tamoxifen in 5% to 10% of patients with ERa-negative tumors are not clear. (lu.se)
  • The pathologic findings, clinical symptoms, and treatment are similar to degenerative aortic stenosis in trileaflet valves. (medscape.com)
  • Many researchers are applying to access currently collected data to generate findings that will improve our understanding of why some people age in healthy ways and other do not. (sfu.ca)
  • Pathak presented the research findings in three women, who ranged in age from 42 to 66. (sciencedaily.com)
  • Diagnosis is based on clinical suspicion, generated by a combination of findings from the history and examination. (bpac.org.nz)
  • This report summarizes the findings of this analysis, which indicate that, despite Medicare coverage of these preventive services, many U.S. adults aged greater than or equal to 65 years did not receive such services in 1995, and state-specific use of these services varied substantially. (cdc.gov)
  • Multi-center studies should be done to determine the extent of resistant organisms in health facilities throughout the country.epidemiology, and the findings should be factored into clinical decision making and program design for disease prevention, screening, and treatment. (who.int)
  • Risk factors that increase the incidence overlap with those predisposing to atherosclerosis and hypertension, smoking, and diabetes and obesity. (medscape.com)
  • By age 75 years, the annual incidence increases to 10 cases per 1000 persons. (clinicaladvisor.com)
  • Objective -To determine incidence rates and potential risk factors for vaccine-associated adverse events (VAAEs) diagnosed within 3 days of administration in dogs. (avma.org)
  • The increased incidence of anxiety and depression in IBD raises the possibility that this condition has an impact on the disease progresses. (frontiersin.org)
  • An increased incidence of heart damage is observed, including acute heart failure, arrhythmias, and myocarditis. (tubitak.gov.tr)
  • The most important clinical association of Kawasaki disease is cardiac disease (incidence roughly 30%), and early studies report a 2% mortality rate secondary to sudden cardiac death. (hawaii.edu)
  • Surveys suggest that overall the incidence is much higher in adults than in children, afflicting 0.6 percent of children under the age of 18 years, approximately 10 to 20 percent of adults and 15 to 40 percent of elderly people. (jcadonline.com)
  • The increased incidence in the younger population could also be due to their exposure to occupation-related trauma predisposing them to onychomycosis or the more common use of occlusive footwear. (jcadonline.com)
  • A healthcare provider's recommendation is one of the most important factors influencing a patient's choice to accept a new prevention product or vaccine. (cdc.gov)
  • The dentist is advised to conduct a clinical examination, consider the patient's signs, symptoms and oral and medical histories, as well as consider the patient's vulnerability to environmental factors that may affect oral health. (fda.gov)
  • The third patient's score of 21 improved after vitamin D treatment to 16, also in the mild range. (sciencedaily.com)
  • Additional management is aimed at controlling symptoms, particularly pain, and improving the patient's quality of life. (bpac.org.nz)
  • The objective of the current ering new classes of antimicrobials and the increasing study was, therefore, to assess the bacteriologic pro- emergence and reemergence of resistant pathogens, file, resistance pattern, and patient's outcome in Lan- mortality from infectious disease is increasing [1]. (who.int)
  • More middle-aged (44.3 percent) and older adults (41.5 percent) are affected compared to younger adults (39.8 percent). (sharecare.com)
  • 01). CONCLUSIONS: Cigarette smoking is already a major cause of death in China, and among middle-aged Shanghai men, about 20% of all deaths during the 1980s were due to smoking. (who.int)
  • IPF is the most common interstitial lung disease among middle-aged and older adults . (medscape.com)
  • Kuwaba K, Kusubata M, Taga Y, Igarashi H, Nakazato K, Mizuno K. Dietary collagen peptides alleviate exercise-induced muscle soreness in healthy middle-aged males: a randomized double-blinded crossover clinical trial. (medlineplus.gov)
  • Future studies are needed to explore whether interventions for anxiety and depression will improve their response to medications and change their prognosis. (frontiersin.org)
  • The risk factors for a poor prognosis are age, comorbidities, and changes in laboratory tests. (tubitak.gov.tr)
  • The relevant tests are the guiding elements of risk assessment, clinical monitoring, disease severity, and prognosis setting and therapy decisionmaking processes. (tubitak.gov.tr)
  • A study reports high levels of CRP associated with clinical prognosis in the time window between 12 and 72 hours after ischemic stroke [ 17 , 18 ]. (hindawi.com)
  • Such knowledge is also crucial for tertiary prevention in the form of identifying high-risk populations followed by surveillance for early-stage HCC detection, so that intervention can be applied to improve overall prognosis. (thieme-connect.com)
  • However, the ACIP and CDC recommend that people with egg allergy of any severity should receive influenza vaccine and that they may receive any influenza vaccine that is otherwise appropriate for age and health status (egg-based or non-egg based). (cdc.gov)
  • Non-alcoholic fatty liver disease (NAFLD) is a heterogeneous condition with a wide spectrum of clinical presentations and natural history and disease severity. (wjgnet.com)
  • Results show "Increased severity" based on "deficient" immunity bearing in mind age-related risk factors. (eurekalert.org)
  • Aside from "Increased severity", even with "Average symptoms," the viral load [V] tends to retain a finite value rather than decreasing to zero, as the virus is not completely eradicated from the host. (eurekalert.org)
  • Next, the research team investigated the influence of age-related immunity levels on disease severity. (eurekalert.org)
  • Some limitations to the study include an inability to control for potentially confounding factors, such as the severity of comorbid conditions. (medpagetoday.com)
  • MAIN OUTCOME MEASURES: Demographic, immunologic, virologic, clinical, laboratory, and drug treatment factors were assessed in stratified and multivariate analyses for their relationship to the presence and severity of fat accumulation and atrophy. (rti.org)
  • Beyond etiology and severity of liver disease, traditional and metabolic risk factors, such as diabetes mellitus, older age, male gender and tobacco smoking, are not enough for HCC risk stratification for surveillance efficacy and effectiveness in NAFLD. (thieme-connect.com)
  • 2 ] [ 3 ] [ 4 ] Therefore, knowledge of the epidemiology and risk factors of HCC is essential for the primary and secondary prevention efforts in the form of screening and treatment of HCC risk factors. (thieme-connect.com)
  • The excess was greatest among men who began smoking before the age of 25 years, about 47% of whom would, at 1987 mortality rates, die between the ages of 35 and 69 years (compared with only 29% of nonsmokers). (who.int)
  • Current HAART use was independently associated with low risk of in-hospital mortality (OR 0.33), while central nervous system symptoms (OR 4.12), sepsis (OR 6.98) and low total lymphocyte counts (OR 3.60) were associated with increased risk. (who.int)
  • Twenty-eight clinical factors from the prior suicide attempt were found to be significantly associated with the hazard of subsequent suicide mortality. (nature.com)
  • A high-risk group with a four-fold increase in suicide mortality risk was identified based on the out-of-sample predicted survival probabilities. (nature.com)
  • Delivery of clinical preventive services to older adults can reduce premature morbidity and mortality while preserving function and enhancing overall quality of life (1,2). (cdc.gov)
  • Expected mortality was obtained from cause, sex, calendar year, and 5-year age-specific death raise for the. (lu.se)
  • CONCLUSION: The increased cerebrovascular mortality may be due to GH deficiency, or to long-term lack or inadequacy of substitution for other pituitary hormones. (lu.se)
  • A clear correlation exists between countries' gross domestic product and their health indicators, such as mortality rates in children less than 5 years of age (highest in low-income countries) or life expectancy (highest in high-income countries). (cdc.gov)
  • Age 65 years, presence of septic shock, and presence of carbapenem-resistant bacteria were independently associated with in- creased in-hospital mortality. (who.int)
  • Conclusion High number of resistant microorganisms was isolated, and increased mortality was documented from infections caused by carbapenem-resistant bacteria. (who.int)
  • The following is a brief clinical description of the main delirium symptoms of hyperactive and hypoactive delirium and associated behaviors. (mentalhealth.com)
  • To better characterise the disease, we need larger, multicentre, multidisciplinary, prospective studies that include all age groups, use uniform diagnostics and report on all symptoms. (ersjournals.com)
  • Information about clinical symptoms of PCD is derived mainly from case series and nonsystematic reviews reflecting expert opinion. (ersjournals.com)
  • image: "Average symptoms" shows the results derived from a baseline model when applying a mathematical model to clinical data. (eurekalert.org)
  • This group was evaluated for the risk factors, presenting symptoms, killip class, type of acute coronary syndrome (STEMI vs NSTEMI), time to presentation to hospital, treatment received (medical management/thrombolysis/PCI/CABG), cardiac arrhythmias, mean ejection fraction, HRCT chest (CORADS grading), any complications and immediate outcome. (scialert.net)
  • Clinical disease: physical signs and symptoms resulting from a sufficiently absorbed toxicant dose. (cdc.gov)
  • Healthcare providers should be aware of underlying conditions that may increase the risk of severe RSV illness, and who might be most likely to benefit from these new vaccines. (cdc.gov)
  • This vaccine provides protection against severe RSV illness to the recipient's baby for up to 6 months of age. (cdc.gov)
  • Some children between the ages of 8 and 19 months who are at increased risk of severe RSV disease before their second RSV season. (cdc.gov)
  • They demonstrated that factors known to be common risks associated with aging - namely (1) Decreased activity by antigen-presenting cells, and (2) Inhibition of interferon signaling by Type I interferon autoantibodies - significantly increased viral production within the body, leading to severe infections (see Fig. 1: Severe infection). (eurekalert.org)
  • One woman's depression score improved from 32 before vitamin D therapy to 12, a change from severe to mild depression. (sciencedaily.com)
  • The clinical picture of drug-induced myopathies may range from asymptomatic or mild myalgias, with or without muscle weakness, which are likely underreported, to chronic myopathy with severe weakness and rarely, even to massive rhabdomyolysis with acute kidney injury (AKI) [ 1 ]. (degruyter.com)
  • Herpes zoster is one of the two clinical syndromes caused by the Varicella-zoster virus (VZV). (clinicaladvisor.com)
  • Mild cognitive impairment (MCI) and dementia are distinct clinical syndromes, both characterized by a decline of cognitive function. (psychiatrist.com)
  • This can be incredibly useful in both clinical practice and for de-challenge/re-challenge investigational trials where the risk of drug-induced SKM injury is present. (degruyter.com)
  • In clinical practice, as well as during drug development and in clinical trials, the diagnosis of SKM injury can be challenging due to the variable symptomology, reliance on patient-self reporting, and lack of highly specific biomarkers, such as those available for cardiac myocyte injury (i.e., cardiac troponins) [ 3 ]. (degruyter.com)
  • In addition, checkpoint inhibitors are more frequently being employed in combination with other agents (including with other checkpoint inhibitors) in clinical practice, as well in hundreds of combination drug trials with other novel biological, targeted, and immunotherapies. (degruyter.com)
  • This heterogeneity of NAFLD is in turn influenced by various factors primarily demographic/dietary factors, metabolic status, gut microbiome, genetic predisposition together with epigenetic factors. (wjgnet.com)
  • Some demographic and clinical factors are reported linked to a worse outcome in IBD. (frontiersin.org)
  • Demographic, clinical and pharmacological data for each patient were also included in the analysis. (rti.org)
  • A comprehensive geriatric assessment (CGA) is an evidence-based clinical assessment which identifies medical, psychosocial, and functional limitations of an older person. (springer.com)
  • Measures selected for inclusion in this Masterclass were chosen based upon their clinical utility with respect to time and resource constraints and ease of administration during a comprehensive assessment for SAIP in community-dwelling older adults. (springer.com)
  • The clinical populations were selected because they represent different types of caregiving stress (e.g., mostly cognitive or physical challenges, or both). (springer.com)
  • however, there is a growing body of evidence that early intensive behavioral intervention based on applied behavior analysis improves cognitive ability, language, and adaptive skills. (aafp.org)
  • In 2014, an Agency for Healthcare Research and Quality systematic review found a growing body of evidence that an applied behavior analysis-based early intensive behavioral intervention, delivered over an extended time frame, improves cognitive ability, language, and adaptive skills in autistic children. (aafp.org)
  • In children with autism spectrum disorder, an applied behavior analysis-based early intensive behavioral intervention delivered over an extended time frame improves cognitive ability, language, and adaptive skills. (aafp.org)
  • Rowe and Kahn defined successful aging to include a low level of disability, having high cognitive and functional capacity, and actively engaging in life events [ 9 ]. (springer.com)
  • 65 years of age (30%-50%) ( 1 ). (cdc.gov)
  • Average age of caregivers was 42 years (SD=9), 83% were female, 82% were white, 73% were married, 17% had high school education or less, 41% were employed full time, and 90% were biological parents. (springer.com)
  • The average child age was 9 years (SD=5). (springer.com)
  • The mean age at presentation is around 75 years. (medscape.com)
  • Participants were 45-84 years of age and free of clinical cardiovascular disease at enrollment (n = 6814). (cdc.gov)
  • SUBJECTS: A total of 9351 adults (6494 men and 2857 women) aged 35 to 64 years at baseline survey during the 1970s. (who.int)
  • average age was 62 years, and 83.9% were women. (doaj.org)
  • This risk increases with age, particularly in women over 35 years of age, and with the number of cigarettes smoked. (nih.gov)
  • For this reason, combination oral contraceptives, including Enskyce™ (desogestrel and ethinyl estradiol tablets USP), should not be used by women who are over 35 years of age and smoke. (nih.gov)
  • What is learned from the CLSA over the coming years will help to improve the lives of people in Canada and around the world. (sfu.ca)
  • Participants were 40-69 years of age at baseline recruitment, a major aim being to acquire as rich data as possible before disease onset. (biorxiv.org)
  • 2 The recommended age for a colon cancer screening is now 45 years old. (medtronic.com)
  • however, implementation for these preventative approaches are lagging behind the increased need due to the substantial population growth of those over 65 years. (springer.com)
  • Those aged younger than 50 years were significantly more likely to have advanced stage CRC compared with those aged 50 or older. (cdc.gov)
  • However, low rates of treatment retention, especially among children (ages 0-14 years), adolescents (ages 15-19 years), and young adults (ages 20-24 years), threaten to undermine epidemic control. (cmi.no)
  • Due to effective vaccination programs for HBV and treatment for HBV and HCV, the population attributable factor (PAF) for HCC from chronic viral hepatitis has started and is expected to continue to decline over the coming years. (thieme-connect.com)
  • The BRFSS is an ongoing, state-based, random-digit-dialed telephone survey of U.S. civilian, noninstitutionalized adults aged greater than or equal to 18 years. (cdc.gov)
  • Of the 113,934 survey participants, 22,849 were aged greater than or equal to 65 years. (cdc.gov)
  • A total of 22,500 (98.5%) respondents aged greater than or equal to 65 years indicated having such coverage. (cdc.gov)
  • In 1995, state-specific estimates of the percentage of persons aged greater than or equal to 65 years who had received influenza vaccinations during the 12 months preceding the survey ranged from 46.2% (95% CI=40.3%-52.1%) (Alabama) to 70.3% (95% CI=65.4%-75.2%) (Utah) (median: 60.6%) ( Table 1 ). (cdc.gov)
  • The percentage of women aged greater than or equal to 65 years who had received a mammogram during the 2 years preceding the survey ranged from 52.7% (95% CI=44.3%-61.1%) (New Jersey) to 80.4% (95% CI=68.8%-92.0%) (Alaska) (median: 65.0%), and prevalences did not vary by region. (cdc.gov)
  • Also consistent with the diagnosis are increases in the ESR, WBC and platelet count. (hawaii.edu)
  • Furthermore, determination of hepatitis B antibody titers could be useful in newly diagnosed CD subjects regardless of age at diagnosis. (mdpi.com)
  • The current vaccination strategy against influenza A of the viral genome and the continuous selection of and B viruses is vulnerable to the unanticipated emergence mutants with improved replication characteristics in the of epidemic strains that are poorly matched by the vaccine. (cdc.gov)
  • Multivariable logistic regression models adjusted for sociodemographic and clinical characteristics were fitted to identify risk factors for advanced stage CRC presentation. (cdc.gov)
  • A number of underlying conditions, such as tinea pedis, nail damage, and nail psoriasis can contribute to risk as well as characteristics such as age and obesity. (jcadonline.com)
  • Maternal Age Risk factors for complications during pregnancy include Preexisting maternal disorders Physical and social characteristics (eg, age) Problems in previous pregnancies (eg, a previous history. (msdmanuals.com)
  • You probably know that overeating and a lack of physical activity contribute to obesity-but there are other risk factors that may not be as apparent. (sharecare.com)
  • Genetics factors into obesity, though it's debated just how much of a role it plays. (sharecare.com)
  • Prenatal risks include advanced paternal or maternal age and maternal metabolic conditions, such as diabetes mellitus, hypertension, and obesity. (aafp.org)
  • Other risk factors include smoking, hypertension, obesity and dyslipidaemia, increasing age and a family history of neuropathy. (bpac.org.nz)
  • Here, the authors review post hoc analyses of efinaconazole topical solution, 10%, in mild-to-moderate onychomycosis and present new data in terms of age and obesity. (jcadonline.com)
  • In addition, they present new data with efinaconazole in terms of age and obesity. (jcadonline.com)
  • Researchers have theorized that social and psychosocial factors increase vulnerability to the deleterious health effects of environmental hazards. (cdc.gov)
  • The modifying role of social and psychosocial factors on the association between exposure to air pollution comprising particulate matter less than 2.5 um in aerodynamic diameter (PM2.5) and blood pressure measures were examined using linear regression models. (cdc.gov)
  • There was no evidence of synergistic effects of higher PM2.5 and adverse social/ psychosocial factors on blood pressure. (cdc.gov)
  • Various physical, medical, psychological, and psychosocial factors may individually or cumulatively impact an older adult's ability to safely age in place. (springer.com)
  • Photo-aging is characterized by changes in pigmentation and collagen deterioration, which causes fine lines and wrinkles to surface. (nutraingredients-usa.com)
  • Progressive deterioration in lung function results in increasing dyspnea, chronic cough, and frequent hospitalizations. (medscape.com)
  • "Results indicated a statistically significant increase in skin carotenoid levels in subjects who ingested Lycoderm, but no remarkable change in the placebo group," ​the authors noted. (nutraingredients-usa.com)
  • Even for well characterized factors, such as smoking and exercise, the lifetime impact on disease is difficult to construct using cross sectional measurements (e.g., number of steps walked last week). (cdc.gov)
  • Gathering clinical measurements over time can improve disease risk estimation. (cdc.gov)
  • Participant eligibility includes age, gender, type and stage of disease, and previous treatments or health concerns. (mayo.edu)
  • Most of the factors we identified as being associated with higher readmission risk, including longer length of stay in the index admission and comorbid conditions (e.g., heart failure, ischemic heart disease, peripheral vascular disease, and diabetes), were less surprising, given they are general risk factors for readmission. (medpagetoday.com)
  • CONCLUSIONS: HIV-associated lipodystrophy is associated with several host, disease, and drug factors. (rti.org)
  • In support of improving patient care, this activity has been planned and implemented by Medscape, LLC and Preventing Chronic Disease . (cdc.gov)
  • Most HCCs develop in the setting of cirrhosis from chronic liver disease, with hepatitis B virus (HBV) and hepatitis C virus (HCV) as the predominant risk factors worldwide. (thieme-connect.com)
  • Many factors determine whether a person exposed to a toxic substance develops a clinical disease. (cdc.gov)
  • Clinical studies suggest that vitamin B6 is independently associated with increased risk for cardiovascular disease. (cdc.gov)
  • Finally, the variant *17 is present in nearly 40% of Caucasians, Blacks, and Asians, and results in increased CYP2C19 activity, higher production of active metabolite, and improved clopidogrel-induced platelet inhibition. (medscape.com)
  • Pathologic antibodies to platelet factor 4 after ChAdOx1 nCoV-19 vaccination. (cdc.gov)
  • Melatonin helps manage sleep disorders, improves daytime behavior, and has minimal adverse effects in children with autism spectrum disorder. (aafp.org)
  • Researchers hope this will improve our understanding of these types of disorders and how genetic factors affect them. (nih.gov)
  • Our results provide new insight into the genetic architecture of the brain with relevance to complex neurological and psychiatric disorders, as well as brain development and aging. (biorxiv.org)
  • Prevalences of chronic bronchitis and clinical farmer's lung were 9.3% and 1.4% respectively. (bmj.com)
  • A logistic regression model was used to evaluate risk factors for chronic bronchitis and clinical farmer's lung. (bmj.com)
  • Also there was a strong positive relation between chronic bronchitis and clinical farmer's lung (odds ratio 19.5 (95% confidence interval 12.1-31.4) after adjustment for confounding variables. (bmj.com)
  • Conclusions and Clinical Relevance -Young adult small-breed neutered dogs that received multiple vaccines per office visit were at greatest risk of a VAAE within 72 hours after vaccination. (avma.org)
  • This study is examining which delivery method of albuterol-inhaled or nebulizer-is better at improving lung function in adult women who have LAM. (nih.gov)
  • Safe aging in place (SAIP) is when an older adult can successfully and comfortably remain in their home despite increasing barriers, including falls. (springer.com)
  • The number of non-drug risk factors substantially increased the likelihood of lipoatrophy. (rti.org)
  • Increasing morbidity was associated with higher age, lower spirometric function, lower predicted VO(2) max, increasing cholesterol, greater BMI, and higher predicted 10 year CHD risk. (cdc.gov)
  • Describes the nature of a clinical study. (mayo.edu)
  • A new clinical study suggests that the ingestible skincare extract Lycoderm can improve skin health and appearance, including radiance, lines and wrinkles. (nutraingredients-usa.com)
  • While former studies have shown that supplementation with Lycoderm correlates with an increase in carotenoid levels in the skin and improves its resilience to environmental factors, the new double-blind, placebo-controlled study is the first to focus on visible beauty parameters. (nutraingredients-usa.com)
  • "Based on the confines and conditions of this study oral supplementation with Lycoderm resulted in significant increase in skin carotenoid level as well as tangible benefits to skin," ​ noted the report. (nutraingredients-usa.com)
  • The Canadian Longitudinal Study on Aging (CLSA) is a large, national, long-term study of more than 50,000 individuals who were between the ages of 45 and 85 when recruited. (sfu.ca)
  • This study is located at the NIH Clinical Center in Bethesda, Maryland. (nih.gov)
  • By using a statewide population-based cancer registry, this study examines sociodemographic and clinical disparities in CRC and characterizes advanced stage CRC risk factors with specific attention to age-specific risk factors. (cdc.gov)
  • Data from this study will inform the development of clinical policies and strategies to improve retention and adherence among adolescents and young adults living with HIV, with the goal of achieving sustained viral load suppression. (cmi.no)
  • Along the vertical axis, the type of encounter with the dental system is categorized (as "New Patient" or "Recall Patient") along with the clinical circumstances and oral diseases that may be present during such an encounter. (fda.gov)
  • In medicine and public health, we often categorize diseases and risk factors into arbitrary groups. (cdc.gov)
  • Moreover, the rapid rise of new therapeutics with the potential to cause SKM injury, such as immunotherapies and targeted therapies, as well as new treatments (such as gene therapy) specifically targeting muscular or neuromuscular diseases, demands an improved clinical strategy to identify myocyte injury and enable appropriate and timely clinical intervention. (degruyter.com)
  • Homocysteine (HCY), a risk factor for cardiovascular and other diseases, is converted to cysteine by PLP-dependent transsulfuration enzymes. (cdc.gov)
  • The future health effects of current smoking patterns are likely to be greater because of the recent large increase in cigarette consumption, particularly at younger ages, in China. (who.int)
  • younger age and basal plasmacytosis in histological biopsies are associated with relapse in UC ( 10 , 11 ). (frontiersin.org)
  • Epidemiologic studies have identified an increase in colorectal cancer (CRC) among younger adults. (cdc.gov)
  • Unfortunately, the available biomarkers for SKM injury do not fully meet the needs for satisfactory detection of drug-induced damage, both in clinical and research settings, mainly due to their low sensitivity and specificity. (degruyter.com)
  • depending on the allele present, laboratory demonstrations of the enzymatic activity of CYP2C19 can be normal, reduced, or increased. (medscape.com)
  • They could just as well suggest that epidemiologists look beyond environmental and socioeconomic factors or remind clinicians to look beyond routine laboratory values. (cdc.gov)
  • Snapshots of clinical and laboratory measurement may have limited predictive ability, whereas the availability of longitudinal data (e.g., electronic health records, wearable devices) could improve prediction. (cdc.gov)
  • The NHANES quality control and quality assurance protocols (QA/QC) meet the 1988 Clinical Laboratory Improvement Act mandates. (cdc.gov)
  • CONCLUSIONS: Although the presence of a single serious or poorly controlled condition may render an individual unfit for safe performance as a firefighter, examination of our cohort suggests that multiple risk factor models or overall clinical assessments are superior means of identifying firefighters with poor health status and increased CHD risk. (cdc.gov)
  • There are three clinical subtypes of delirium categorized according to psychomotor activity and cause. (mentalhealth.com)
  • Participants aged 1 year and older were tested. (cdc.gov)
  • The same pattern emerged across different health domains, including caregiver stress, with the community sample caregivers reporting better health and less stress than any of the clinical samples. (springer.com)
  • In a recent commentary , McCarthy and Birney argue that these studies can provide an evidentiary path to personalized medicine - but only if they are done in diverse populations, and integrate rare and common genetic risk factors with measurements of changing environments and health indices over time. (cdc.gov)
  • The guidelines are not substitutes for clinical examinations and health histories. (fda.gov)
  • To augment an older adult's ability and resources to safely age in place, key physical, medical, and social determinants of health must be addressed. (springer.com)
  • Fig. 1 Age-standardized death rates of liver cancer by World Health Organization region from 2010 to 2019. (thieme-connect.com)
  • To assess current state-specific levels of use of these services among Medicare beneficiaries, CDC and the Health Care Financing Administration (HCFA) analyzed data from the 1995 Behavioral Risk Factor Surveillance System (BRFSS). (cdc.gov)
  • Global health reflects the realities of globalization, especially the increased movement of persons and goods, and the global dissemination of infectious and noninfectious public health risks. (cdc.gov)
  • Global health is concerned with protecting the entire global community, not just its poorest segments, against threats to health and with delivering essential and cost-effective public health and clinical services to the world's population. (cdc.gov)
  • With socioeconomic development, basic health indicators improve but so do countries' abilities to shoulder more of their own health expenditures. (cdc.gov)
  • Background Prior studies indicated increased antimicrobial resistance in Ethiopia, with related health, economic, and environmental costs. (who.int)
  • Increased cost pressure, technological advancements and constantly shifting regulations are creating new challenges across the healthcare industry, says Bain Partner Joshua Weisbrod. (bain.com)
  • In addition to the personal burden of falling, healthcare expenditures associated with emergency department visits after a fall averages $3038 United States Dollars (USD) and increases to $38,412 USD if an individual requires hospitalization [ 7 ]. (springer.com)
  • Fundamental growth drivers include population growth, surging healthcare expenditure on a global scale, aging population and GDP growth. (medgadget.com)
  • We also demonstrate our commitment to increasing access to healthcare through far-reaching policies, programs and partnerships. (merck.com)
  • Help us make reference on Medscape the best clinical resource possible. (medscape.com)
  • Although the primary mechanism of this action is inhibition of ovulation, other alterations include changes in the cervical mucus, which increase the difficulty of sperm entry into the uterus, and changes in the endometrium which reduce the likelihood of implantation. (nih.gov)
  • This definition was updated in 2015 to include influences on successful aging that encompass the person's interpersonal environment. (springer.com)
  • Although the cause of IPF is unknown, risk factors include a history of smoking, family history, and genetic predispositions. (medscape.com)
  • Other possible bottlenecks include lack of manufacturing standardization, increasing lead time and logistics costs. (medgadget.com)
  • Approximately 30% of the US population carries a CYP2C19 loss-of-function (LOF) allele, which puts these individuals at increased risk for major adverse cardiovascular events (MACE) if treated with clopidogrel after undergoing percutaneous coronary intervention. (medscape.com)
  • The CGA is useful to dictate individualized exercise/intervention prescription to address identified areas of increased risk. (springer.com)
  • CDC recommends that adults 60 and older may receive a single dose of RSV vaccine, using shared clinical decision-making. (cdc.gov)
  • For the upcoming 23-24 flu season, influenza vaccination of all people aged six months and older who do not have contraindications continues to be recommended. (cdc.gov)
  • After taking a strand of hair that represented two months of hair growth from 2,527 adults aged 54 and older, scientists found that the volunteers with higher cortisol levels were also more likely to have a larger waist circumference, a higher weight, and a higher BMI. (sharecare.com)
  • Treatment is usually recommended without the need for a DXA scan in older ages. (nursinginpractice.com)
  • Although many older adults strive to remain safely in their homes, often termed "safe aging in place" (SAIP), this goal often becomes less feasible over time and may necessitate assistance to remain living at home safely. (springer.com)
  • The alarming rate of falls among older adults, in combination with reports that 38% of these falls will require medical treatment, warrants proactive measures to reduce falls and fall risk in the aging population [ 6 ]. (springer.com)
  • Therefore, even a moderate reduction in falls can improve an older adult's ability to safely age in place and has the potential for substantial cost savings [ 8 ]. (springer.com)
  • Taking collagen peptides by mouth seems to improve skin hydration and skin elasticity in older people. (medlineplus.gov)
  • The research team sought to clarify whether such persistent infections within infected hosts actually occur, and if so, to identify the causative factors. (eurekalert.org)
  • The ability to identify risk factors for suicidal behavior is critical to selected and indicated prevention efforts among those at elevated risk of suicide. (nature.com)
  • A number of comorbidities and risk factors complicate the successful management of onychomycosis. (jcadonline.com)
  • At the end of follow-up, adherence increased with the three types of anti-TNFs treatment. (doaj.org)
  • Moore KJ, Sussman DA, Koru-Sengul T. Age-Specific Risk Factors for Advanced Stage Colorectal Cancer, 1981-2013. (cdc.gov)
  • Diabetic peripheral neuropathy develops in up to half of all people with diabetes and is one of the main risk factors contributing to foot ulceration and eventual amputation. (bpac.org.nz)