• cytometer
  • SAN DIEGO, CALIF. - (July 31, 2017) - Beckman Coulter Life Sciences has received 510(k) clearance from the U.S. Food and Drug Administration (FDA) for its latest clinical flow cytometry product, the Navios EX flow cytometer , to be used in the clinical laboratory in the US. (beckman.com)
  • The compact, 10-color Navios EX incorporates the advanced optics and laser technology of the company's award-winning CytoFLEX research flow cytometer. (beckman.com)
  • Blood (2 microliters) is added to 2 ml of 0.4 microM thiazole orange in phosphate buffered saline, incubated at room temperature for 90 minutes, and analysed on a Coulter EPICS Profile flow cytometer, with gating for red cells on the basis of forward and right angled light scatter. (bmj.com)
  • A flow cytometer allows simultaneous multiparametric analysis of the physical and chemical characteristics of up to thousands of particles per second. (wikipedia.org)
  • A common variation involves linking the analytical capability of the flow cytometer to a sorting device, to physically separate and thereby purify particles of interest based on their optical properties. (wikipedia.org)
  • The first label-free high-frequency impedance flow cytometer based on a patented microfluidic "lab-on-chip", Ampha Z30, was introduced by Amphasys (2012). (wikipedia.org)
  • At the 5th American Engineering Foundation Conference on Automated Cytology in Pensacola (Florida) in 1976 - eight years after the introduction of the first fluorescence-based flow cytometer (1968) - it was agreed to commonly use the name "flow cytometry", a term that quickly became popular. (wikipedia.org)
  • A flow cytometer is similar to a microscope, except that, instead of producing an image of the cell, flow cytometry offers high-throughput, large-scale, automated quantification of specified optical parameters on a cell-by-cell basis. (wikipedia.org)
  • A flow cytometer has five main components: a flow cell, a measuring system, a detector, an amplification system, and a computer for analysis of the signals. (wikipedia.org)
  • Acquisition is mediated by a computer physically connected to the flow cytometer, and the software which handles the digital interface with the cytometer. (wikipedia.org)
  • T cells, B cells and NK cells are nearly impossible to distinguish under a microscope, therefore one must use a flow cytometer to distinguish them. (wikipedia.org)
  • Reagents
  • The company has since developed a wide variety of reagents and devices optimized for manual and automated cell separation procedures, the lab bench, and clinical research. (wikipedia.org)
  • today's
  • Mack Fulwyler was the inventor of the forerunner to today's flow cytometers - particularly the cell sorter. (wikipedia.org)
  • 2001
  • In 2001 the organization published the first flow based reference method for platelet counting. (wikipedia.org)
  • research
  • Since clinical research can be subject to uncontrollable timetables and only few departments have access to a dedicated laboratory, the quantification of ROS is challenging. (pubmedcentralcanada.ca)
  • Our current method is easy to perform, implementable into clinical research and is able to detect different ROS responses. (pubmedcentralcanada.ca)
  • Miltenyi Biotec's flow cytometry products are used across many distinguished research centers around the world, including Caltech and the Pasteur Institute. (wikipedia.org)
  • involves
  • Electrophysiology typically involves the measurements of voltage change or electric current flow on a wide variety of scales from single ion channel proteins to whole tissues. (wikipedia.org)
  • similar
  • Modern flow cytometers are able to analyze many thousand particles per second, in "real time," and, if configured as cell sorters, can actively separate and isolate particles at similar rates having specified optical properties. (wikipedia.org)
  • medical
  • Under the CLIA law, only the US Department of Health and Human Services approved Board Certified Ph.D., D Sc, or MD and DO can perform the duties of a Medical or Clinical Laboratory Director. (wikipedia.org)
  • cancer
  • Today, both the clinical workhorses and the powerful multi-laser, multi-detector, sorting machinery, coupled with sophisticated computers and storage devices and the increasing storehouse of markers and dyes, are taking us to the limit and beyond in finding answers to the cause and cure of cancer. (google.com)
  • known
  • This variant of Hyperimmunoglobulin E syndrome (HIES) was first described in 2004 and this clinical entity is known to be due to having biallelic germline mutations in the DOCK8 gene. (wikipedia.org)