• Macrolides
  • Macrolides, clindamycin and aminoglycosides (with all these three having other potential mechanisms of action as well), have evidence of inhibition of ribosomal translocation. (wikipedia.org)
  • Macrolides and clindamycin (both also having other potential mechanisms) cause premature dissociation of the peptidyl-tRNA from the ribosome. (wikipedia.org)
  • hypersensitivity
  • Not a first-line agent, but AAP and AAFP state clindamycin may be considered in individuals with penicillin hypersensitivity who may have AOM caused by penicillin-resistant S. pneumoniae . (drugs.com)
  • efficacy
  • Hi i notice no one has answered you question and i'm sure you have found out the answer for yourself now, but drinking alcohol whilst taking clindamycin will reduce the efficacy of the drug, so you should avoid it. (drugs.com)
  • infections
  • Because clindamycin has been associated with severe colitis (potentially fatal), it should be reserved for treatment of serious infections when less toxic anti-infectives are inappropriate. (drugs.com)
  • Clindamycin can also be used "off-label" to prevent and treat other opportunistic infections of HIV infection. (thebody.com)
  • What HIV-Related Opportunistic Infections Is Clindamycin Used For? (thebody.com)
  • The above list may not include all of the HIV-related uses of clindamycin recommended in the Guidelines for the Prevention and Treatment of Opportunistic Infections in HIV-Infected Adults and Adolescents . (thebody.com)
  • treatment
  • Use of clindamycin also may be considered if AOM persists after treatment with amoxicillin and clavulanate or ceftriaxone and tympanocentesis is not available to make a bacteriologic diagnosis. (drugs.com)
  • 124 128 257 When a parenteral regimen is indicated for treatment of PID, IV clindamycin in conjunction with an IV or IM aminoglycoside (e.g., gentamicin) is one of the recommended regimens. (drugs.com)
  • Avoid using a condom as a birth control method while you are using clindamycin vaginal and for at least 72 hours (3 days) after your treatment ends. (wellspan.org)
  • vitro
  • Patient-derived isolates of Plasmodium falciparum from the Peruvian Amazon have been reported to be resistant to clindamycin as evidenced by in vitro drug susceptibility testing. (wikipedia.org)
  • resistant
  • If the area of inhibition around the clindamycin disk is "D" shaped, the test result is positive and clindamycin should not be used due to the possibility of resistant pathogens and therapy failure. (wikipedia.org)
  • pregnant
  • In clinical trials with pregnant women, use of clindamycin during the second and third trimesters was not associated with an increase in birth defects. (thebody.com)
  • Talk to your health care provider about possible risks with taking clindamycin when pregnant. (thebody.com)
  • oral
  • Store clindamycin capsules, granules for oral solution, and solution for intravenous use at room temperature, 68°F to 77°F (20°C to 25°C). (thebody.com)