• In the obese, circulating free fatty acids (or non-esterified fatty acids), NEFA, are often elevated. (blogspot.com)
  • Cows fed the W20 diet had a lower plasma concentration of β-hydroxybutyrate (BHBA), non-esterified fatty acids (NEFA), cholesterol, triglyceride, and total antioxidative capacity (TAC), and a higher plasma concentration of glucose, insulin, malonaldehyde (MDA), super oxygen dehydrogenises (SOD), and glutathione peroxidase (GSH-Px) than cows fed the W0 diet. (biomedcentral.com)
  • A fat tolerance test evidenced delayed plasma triglyceride clearance and greater transient availability of non-esterified fatty acids (NEFA) during the post-prandial state in the apoCIII mice plasma. (biomedcentral.com)
  • Transgenic mice overexpressing human apoCIII have marked elevated TG and non-esterified fatty acid (NEFA) levels [ 21 ]. (biomedcentral.com)
  • This post discusses: Downregulation of Adipose Tissue Fatty Acid Trafficking in Obesity, A Driver for Ectopic Fat Deposition? (blogspot.com)
  • Presented without comment on the content per se: Role of the Adipocyte, Free Fatty Acids, and Ectopic Fat in Pathogenesis of Type 2 Diabetes Mellitus This is probably the most exhaustively referenced review article I've ever come across on the etiology of MetS and T2 Diabetes and the role of adipose tissue. (blogspot.com)
  • Fasting also promotes lipolysis in adipose tissue to release nonesterified fatty acids which are converted into ketone bodies in the liver though mitochondrial oxidation and ketogenesis. (irjs.info)
  • In the fasted state or during exercise, gas substrates (e.g. glucose and TAG) are released from your liver into the blood circulation and metabolized by muscle mass, adipose cells, and additional extrahepatic cells. (irjs.info)
  • The Combination of Resveratrol and Quercetin Attenuates Metabolic Syndrome in Rats by Modifying the Serum Fatty Acid Composition and by Upregulating SIRT 1 and SIRT 2 Expression in White Adipose Tissue - Evid Based Complement Alternat Med. (qualitycounts.com)
  • Several studies have demonstrated that NAFLD is associated with insulin resistance leading to a resistance in the antilipolytic effect of insulin in the adipose tissue with an increase of free fatty acids (FFAs). (mdpi.com)
  • Among the peripheral signals that are generated to regulate the uptake of food, signals from adipose tissue are of major relevance and involve the maintenance of energy homeostasis through processes such as lipogenesis, lipolysis, and oxidation of fatty acids. (wjgnet.com)
  • This may be the result of visceral adipose tissue's excess fatty acids draining into the portal vein. (paleorecipediet.com)
  • In lipodystrophy there is insufficient adipose tissue to absorb the postprandial influx of fatty acids, so these fatty acids will again be directed to other tissues. (cambridge.org)
  • This view of the link between adipose tissue and insulin resistance emphasises the important role of adipose tissue in 'buffering' the daily influx of dietary fat entering the circulation and preventing excessive exposure of other tissues to this influx. (cambridge.org)
  • We previously hypothesized that apoCIII overexpression would compromise fatty acid delivery to adipose tissues and would thus contribute to resistance to diet-induced obesity, similarly to what was described for overexpression of apoCI [ 15 ]. (biomedcentral.com)
  • Insulin Regulation of Regional Free Fatty Acid Metabolism Alternate Title: Why I had a fatter ass before low carb? (blogspot.com)
  • Aberrant energy rate of metabolism in the liver promotes insulin resistance, diabetes, and nonalcoholic fatty liver diseases (NAFLD). (irjs.info)
  • The more a child's body has fatty tissue, particularly inside and between the muscle and skin around the belly, the more insulin-resistant their cells become. (paleorecipediet.com)
  • Björntorp , P ( 1994 ) Fatty acids, hyperinsulinemia, and insulin resistance: which comes first? (cambridge.org)
  • Non-alcoholic fatty liver disease is associated with obesity, non-insulin dependent diabetes, and hypertriglyceridemia and represents the hepatic manifestation of the metabolic syndrome[ 4 ]. (wjgnet.com)
  • Long chain polyunsaturated fatty acid (LC-PUFA), including docosahexaenoic acid (DHA) and arachidonic acid (AA), are incorporated into membrane phospholipids and, apart from their structural role in these membranes, they also act as precursors of autocoid signaling molecules (e.g., docosanoids) and as potent activators of a number of gene transcription factors (e.g., peroxisome proliferator activated receptors). (bioseek.eu)
  • Malnutrition Zinc Clinically: erythematous crusting erosive sometimes bullous dermatitis periorificial: buccal, nasal, palpebral, anal, vulval, genital, flexural progressive alopecia diagnosis and treatment: reduced blood Zn and alkaline phosphatase, sometimes also reduced non esterified essential fatty acids (linoleic and arachidonic acid). (globale-dermatologie.com)
  • Corticosteroids inhibit formation of arachidonic acid from phospholipids when cell membranes are damaged. (unboundmedicine.com)
  • Dysfunction of liver signaling and rate of metabolism causes or predisposes to nonalcoholic fatty liver disease (NAFLD) and/or type 2 diabetes. (irjs.info)
  • Intrahepatic fat deposition has been demonstrated in patients with nonalcoholic fatty liver disease (NAFLD). (wjgnet.com)
  • Nonalcoholic fatty liver disease (NAFLD) is highly prevalent and can result in nonalcoholic steatohepatitis (NASH) and progressive liver disease including cirrhosis and hepatocellular carcinoma. (wjgnet.com)
  • An estimated 30% of adults and 10% of children and adolescents in the United States have nonalcoholic fatty liver disease (NAFLD), defined as liver fat content exceeding 5% (Figure 1 )[ 1 - 3 ]. (wjgnet.com)
  • NEFAs are oxidized in hepatic mitochondria through fatty acid oxidation and generate ketone body (ketogenesis). (irjs.info)
  • Non-alcoholic fatty liver disease is marked by hepatic fat accumulation not due to alcohol abuse. (mdpi.com)
  • Hyperlipidemia comprises a heterogeneous group of disorders, characterized by high levels in one or more lipids and/or lipoproteins [atherogenic free fatty acids (FA), triglycerides (TG) (hypertriglyceridemia), small dense low-density lipoprotein cholesterol (LDL-C) (hypercholesterolemia), and apolipoprotein (apo) B], and/or low level in antiatherogenic high density lipoprotein cholesterol (HDL-C), in the circulation [ 1 - 3 ]. (hindawi.com)
  • Hydrophobicity, one of the distinctive properties of many dietary lipids, that makes triglycerides excellent molecules for energy storage, creates problems when such molecules are digested in the gastrointestinal tract, absorbed in the small intestine, and finally transported in the circulation after absorption or mobilization from body stores. (tuscany-diet.net)
  • They are proteins that catalyze the partial hydrolysis of triglycerides into a mixture of free fatty acids and acylglycerols. (tuscany-diet.net)
  • A single bout of prolonged aerobic exercise lowers plasma TAG (triacylglycerol) concentrations the next day by increasing the efficiency of VLDL (very-low-density lipoprotein)-TAG removal from the circulation. (portlandpress.com)
  • TAG is definitely stored in lipid droplets in hepatocytes or secreted into the blood circulation as very low-density lipoprotein (VLDL) particles. (irjs.info)
  • Circulating nonesterified fatty acid level as a predictive risk factor for sudden death in the population J . Circulation, 2001, 104(7):756-761. (xml-journal.net)
  • Delayed milk production and poor feeding lead to decreased caloric intake, dehydration , and increased enterohepatic circulation, resulting in higher serum bilirubin concentration. (medscape.com)
  • Food is definitely digested in the gastrointestinal (GI) tract, and glucose, fatty acids, and amino acids are absorbed into the bloodstream and transported to the liver through the portal vein blood circulation system. (irjs.info)
  • In the postprandial state, glucose is definitely condensed into glycogen and/or converted into fatty acids or amino acids in the liver. (irjs.info)
  • Amino acids are metabolized to provide energy or CC-5013 novel inhibtior CC-5013 novel inhibtior used to synthesize proteins, glucose, and/or additional bioactive molecules. (irjs.info)
  • Multiple nutrient, hormonal, and neuronal signals have been recognized to regulate glucose, lipid, and amino acid rate of metabolism in the liver. (irjs.info)
  • Fasting and Post-Load Glucose and Non-Esterified Fatty Acids and Risk of Heart Failure and Its Subtypes in Older Adults. (ucsf.edu)
  • 1,2,3 Het zijn polysachariden die bestaan ​​uit (1-3)- en (1-4)-bèta-D-gekoppelde polymeren van glucose die ofwel onvertakt ofwel met 1-6-bèta-vertakkingen zijn. (sohf.nl)
  • In addition, C3R inhibited the formation of cholesterol micelles and bound to primary and secondary bile acid. (biomedcentral.com)
  • Het consumeren van producten die ten minste 3,6 gram oplosbare vezels bevatten, inclusief bètaglucanen, per dag kan het risico op hart- en vaatziekten verminderen wanneer ze worden geconsumeerd als onderdeel van een dieet met weinig verzadigd vet en cholesterol. (sohf.nl)
  • De Amerikaanse Food and Drug Administration (FDA) staat toe dat voedselproducten die ten minste 750 mg bètaglucanen per portie bevatten, worden geëtiketteerd met een gezondheidsclaim waarin staat dat het risico op coronaire hartziekte (CHZ) kan verminderen wanneer het wordt geconsumeerd als onderdeel van een dieet met weinig verzadigd vet en cholesterol. (sohf.nl)
  • 11,12,13,14,15,16,17,18 In 1993 keurde de FDA een gezondheidsclaim goed waarin stond dat het consumeren van producten die ten minste 3 gram bètaglucanen per dag bevatten, als onderdeel van een dieet met weinig verzadigd vet en cholesterol, het risico op hart- en vaatziekten kan verminderen. (sohf.nl)
  • 25,26,27,28,29,30,31,32 Meta-analyses van beschikbaar klinisch onderzoek naar van haver afgeleide bètaglucanen tonen aan dat inname van ten minste 3 gram per dag het LDL-cholesterol verlaagt met ongeveer 4 - 10 mg/dL en het totale cholesterol met 4 - 12 mg/dL, maar geen invloed heeft op hoge dichtheid lipoproteïne (HDL) cholesterol- of triglycerideniveaus in vergelijking met controlediëten. (sohf.nl)
  • Leptin and adiponectin can augment the oxidation of fatty acid in liver by activating the nuclear receptor super-family of transcription factors, namely peroxisome proliferator-activated receptor (PPAR)-α. (wjgnet.com)
  • They have an energy density more than twice that of carbohydrates (about 9 kcal/g vs. about 3.75) and amino acids. (tuscany-diet.net)
  • The 32-amino acid polypeptide BNP is secreted attached to a 76-amino acid N-terminal fragment in the prohormone called NT-proBNP (BNPT), which is biologically inactive. (encyclopedia.pub)
  • BNP is synthesized as a 134-amino acid preprohormone (preproBNP), encoded by the human gene NPPB. (encyclopedia.pub)
  • proBNP is subsequently cleaved between arginine-102 and serine-103 by a specific convertase (probably furin or corin) into NT-proBNP and the biologically active 32-amino acid polypeptide BNP-32, which are secreted into the blood in equimolar amounts. (encyclopedia.pub)
  • C 4 H 7 NO 4 , a nonessential amino acid. (unboundmedicine.com)
  • Incidence and treatment of no-reflow after percutaneous coronary intervention J . Circulation, 1994, 89(6):2514-2518. (xml-journal.net)
  • The study included 56 individuals with obesity, of whom 30 individuals underwent Roux-en-Y gastric bypass surgery (RYGB) and twenty-six underwent sleeve gastrectomy (SG). (biomedcentral.com)
  • Bètaglucanen worden ingezet bij diabetes , gewichtsverlies , infecties, wondgenezing en darmklachten . (sohf.nl)
  • 34 De effecten van haver afgeleide bètaglucanen op het cholesterolgehalte lijken groter te zijn bij patiënten met diabetes en patiënten met een hoger LDL-cholesterolgehalte. (sohf.nl)
  • Among these, 41 studies were ex- in the release of higher amounts of fatty challenge to Arab governments due to cluded because the samples were not acids into the circulation. (who.int)
  • The platform's capability to maintain long-term viability and functionality of white adipocytes was confirmed by real-time monitoring of fatty acid uptake, by quantification of metabolite release into the effluent media as well as by an intact responsiveness to a therapeutic compound. (nature.com)
  • They must release their fatty acids to be used as a source of energy. (tuscany-diet.net)
  • Pyruvic acid Oxaloacetic acid The reaction it catalyzes is: pyruvate + HCO− 3 + ATP → oxaloacetate + ADP + P It is an important anaplerotic reaction that creates oxaloacetate from pyruvate. (wikipedia.org)
  • Pyruvate is definitely channeled into the mitochondria and completely oxidized to generate ATP through the tricarboxylic acid (TCA) cycle (Fig. 1) and oxidative phosphorylation. (irjs.info)
  • Docosahexaenoic acid (DHA) is a structural constituent of membranes specifically in the central nervous system. (bioseek.eu)
  • The apparent digestibility of nutrients was not affected by the dietary treatments, except that the digestibility of neutral detergent fibre (NDF) and acid detergent fibre (ADF) was reduced in cows fed the W20 diet compared with cows fed the W0 and W10 diets, and cows fed the BP10 diet had higher NDF and ADF digestibility than the cows fed the W20 diet. (biomedcentral.com)
  • The acid is a known carcinogen, and its use has been associated with and may cause end-stage renal disease and cancers of the urinary tract that may occur many years after usage has stopped. (unboundmedicine.com)
  • C 7 H 6 O 2 , a white crystalline acid having a slight odor. (unboundmedicine.com)
  • H 3 BO 3 , a white crystalline acid that in water forms a very weak acid solution poisonous to plants and animals. (unboundmedicine.com)
  • La présente analyse récapitule les facteurs pathologiques majeurs liant l'obésité au diabète, en se concentrant sur les données épidémiologiques actuelles relatives aux patients diabétiques obèses dans le monde arabe, l'étiologie de la maladie et les déterminants génétiques du diabète et de l'obésité. (who.int)
  • No-reflow phenomenon and lesion morphology in patients with acute myocardial infarction J . Circulation, 2002, 105(18):2148-2152. (xml-journal.net)
  • Myocardial perfusion patterns related to Thrombolysis In Myocardial Infarction perfusion grades after coronary angioplasty in patients with acute anterior wall myocardial infarction J . Circulation, 1996, 93(11):1993-1999. (xml-journal.net)
  • It is stable in an acid environment and therefore remains active in the stomach, and also in the small intestine in the case where there is no proper pancreatic secretion of bicarbonate. (tuscany-diet.net)