• In enzymology, a cinnamyl-alcohol dehydrogenase (EC 1.1.1.195) is an enzyme that catalyzes the chemical reaction cinnamyl alcohol + NADP+ ⇌ {\displaystyle \rightleftharpoons } cinnamaldehyde + NADPH + H+ Thus, the two substrates of this enzyme are cinnamyl alcohol and NADP+, whereas its 3 products are cinnamaldehyde, NADPH, and H+. (wikipedia.org)
  • the gene encoding the monolignol biosynthetic enzyme cinnamyl alcohol dehydrogenase (cad, e.c. 1.1.1.195) can be expressed in response to different developmental and environmental cues. (liverpool.ac.uk)
  • In the last step, a NADPH-dependent cinnamyl alcohol dehydrogenase, also called monolignol dehydrogenase (EC 1.1.1.195), catalyzes the reduction of the aldehyde group to an alcohol group, with the formation of the aforementioned monolignols. (tuscany-diet.net)
  • The systematic name of this enzyme class is cinnamyl-alcohol:NADP+ oxidoreductase. (wikipedia.org)
  • The enzyme Cinnamyl Alcohol Dehydrogenase (CAD) catalyses the last step of lignin monomer synthesis, and is considered as a molecular marker of cell wall lignification in different plants species. (ox.ac.uk)
  • Cinnamyl alcohol dehydrogenase (CAD), as a key enzyme of plant secondary metabolism, especially lignin synthesis, is closely related to plant growth and development and resistance to pathogen invasion. (landmarkind.com)
  • Inheritance, gene expression, and lignin characterization in a mutant pine deficient in cinnamyl alcohol dehydrogenase. (ox.ac.uk)
  • Sequence analysis and functional characterization of the promoter of the Picea glauca Cinnamyl Alcohol Dehydrogenase gene in transgenic white spruce plants. (ox.ac.uk)
  • Isolation and characterization of Phenyl Alanine Ammonia Lyase Gene and Cinnamyl Alcohol Dehydrogenase Gene from hard and soft seeded varieties of pomegranate. (yspuniversity.ac.in)
  • Characterization of cinnamyl alcohol dehydrogenase of Helicobacter pylori. (bvsalud.org)
  • genetic analysis of cinnamyl alcohol dehydrogenase in loblolly pine: single gene inheritance, molecular characterization and evolution. (liverpool.ac.uk)
  • The products of CAD, cinnamyl alcohols, are the precursors of lignin, a major cell wall polymer of plant vascular tissues. (ox.ac.uk)
  • electrophoretic analysis of coniferyl alcohol oxidase and related laccases. (liverpool.ac.uk)
  • gradient gel electrophoretic methods enabled a distinction to be made between coniferyl alcohol oxidase (cao) of lignifying cell walls and a pi approximately 9 pine 'laccase' recently implicated in lignification (science 1993 260, 672). (liverpool.ac.uk)
  • The first three reactions reduce the carboxylic group of the hydroxycinnamates to alcohol group, with formation of the corresponding alcohols, called monolignols, that is, p-coumaric alcohol, sinapyl alcohol and coniferyl alcohol. (tuscany-diet.net)
  • S)-2-Methyl-1-butanol, also known as 2-methyl butanol-1 or 2-methylbutyl alcohol, belongs to the class of organic compounds known as primary alcohols. (ymdb.ca)
  • Primary alcohols are compounds comprising the primary alcohol functional group, with the general structure RCOH (R=alkyl, aryl). (ymdb.ca)
  • However, the latest research shows that using dehydrogenase to catalyze the reduction of cinnamyl alcohol and its derivatives in NADPH can effectively synthesize CAD. (landmarkind.com)
  • This research achievement is a major breakthrough in solving the problem of synthesis of cinnamyl alcohol dehydrogenase, and has greatly reduced the manufacturing cost of CAD. (landmarkind.com)
  • Of course, in this process, there is no doubt about the role of cinnamyl alcohol, which is the basis of CAD synthesis. (landmarkind.com)
  • The quality of cinnamyl alcohol directly affects the synthesis quality of CAD and its application in performance. (landmarkind.com)
  • Other names in common use include cinnamyl alcohol dehydrogenase, and CAD. (wikipedia.org)
  • This review article summarizes the novel pharmacotherapeutic approaches used in the treatment of alcohol addiction by focusing on the drugs, which include neramexane, gabapentin, baclofen, aripiprazole, nalmafene, and quetiapine. (afpm.org.my)
  • Environmental stresses of field growth allow cinnamyl alcohol dehydrogenase-deficient Nicotiana attenuata plants to compensate for their structural deficiencies. (mpg.de)
  • NADP(H)-dependent glutamate dehydrogenases (GDH) in lower organisms have stronger ammonium affinity than those in higher plants. (jipb.net)
  • Thus, (S)-2-methyl-1-butanol is considered to be a fatty alcohol (S)-2-Methyl-1-butanol exists in all eukaryotes, ranging from yeast to plants to humans. (ymdb.ca)
  • As more is being understood about the neurobiology of alcohol addiction as well as the unique pharmacological action of these drugs, new agents are evaluated for potential benefits when used as an adjunct in combination therapy. (afpm.org.my)
  • Putative cinnamyl alcohol dehydrogenase 4 OS=Oryza. (ntu.edu.sg)
  • protein_coding" "Cz03g11040.t1","No alias","Chromochloris zofingiensis","Ribosomal protein/NADH dehydrogenase domain [Interproscan]. (ntu.edu.sg)
  • In this study, genetically modified Populus trichocarpa wood specimens with down-regulated cinnamyl alcohol dehydrogenase, cinnamate 3-hydroxylase, and cinnamate 4-hydroxylase with altered lignin contents and/or lignin structures were utilized to probe the relationship between the lignin content, lignin monomer composition, and thermo-mechanical properties of solid wood. (ncsu.edu)
  • Lignin and lignans in plant defence: Insight from expression profiling of cinnamyl alcohol dehydrogenase genes during development and following fungal infection in Populus. (sciendo.com)
  • Lignin is a heterogeneous phenolic polymer mainly composed of p -hydroxyphenyl (H), guaiacyl (G), and syringyl (S) phenylpropanoid units that are derived from the monolignols p -coumaryl, coniferyl, and sinapyl alcohol, respectively [ 9 ]. (biomedcentral.com)
  • Probable cinnamyl alcohol dehydrogenase 8A OS=Oryza. (ntu.edu.sg)
  • Probable cinnamyl alcohol dehydrogenase 6 OS=Oryza. (ntu.edu.sg)
  • Using both of these substrates it was demonstrated that cinnamyl alcohol dehydrogenase from lignifying Forsythia tissue specifically removes the pro-R-hydrogen atom of coniferyl alcohol in the oxidation to the aldehyde. (uni-muenchen.de)
  • Then, the oxidative radicalization of taxifolin and coniferyl alcohol produces silymarin. (genominfo.org)
  • Encodes a catalytically active cinnamyl alcohol dehydrogenase which uses p-coumaryl aldehyde as a preferred substrate. (or.jp)
  • Substrate-specificity of LACCASE 8 facilitates polymerization of caffeyl alcohol for C-lignin biosynthesis in the seed coat of Cleome hassleriana. (unt.edu)
  • Further studies showed that the activity of polyphenol oxidase (PPO), peroxidase (POD), phenylalanine ammonia lyase (PAL), 4-coumaryl coenzyme A ligase (4CL), cinnamic acid-4-hydroxylase (C4H) and cinnamyl alcohol dehydrogenase (CAD) was significantly increased by the treatment of the extract at 150 mg/mL (P (spkx.net.cn)
  • Cinnamyl Alcohol is an active component from chestnut flower, inhibits increased PPARγ expression, with anti-obesity activity. (medchemexpress.com)
  • 9. Negative regulators of plant immunity derived from cinnamyl alcohol dehydrogenases are targeted by multiple Phytophthora Avr3a-like effectors. (nih.gov)