• Adult T-cell leukemia/lymphoma (ATLL) is a rare and aggressive disease caused by human T-cell lymphotropic virus type 1 that predominantly affects Japanese and Caribbean populations. (oncotarget.com)
  • The presence of antibodies to HTLV-I or HTLV-II indicates that a person is infected with the virus. (cdc.gov)
  • Since then, all donations of whole blood and blood components in the United States have been screened for antibodies to HTLV-I. The screening tests that were licensed, as well as the investigational supplementary tests used to confirm seroreactivity (Western immunoblot and radioimmunoprecipitation assay), do not reliably differentiate between antibodies to HTLV-I and the closely related HTLV-II. (cdc.gov)
  • In addition, the licensed screening tests, which use HTLV-I antigens, vary in their sensitivity to detect antibodies to HTLV-II (4,5). (cdc.gov)
  • Within the past 2 years, investigational peptide- and recombinant protein-based serologic assays that can more easily differentiate the antibodies to HTLV-I and HTLV-II have been developed (8,9). (cdc.gov)
  • and human T -cell antigens recognized by certain monoclonal antibodies on both immature and mature T -cells. (science-connections.com)
  • In the high endemic areas, 0.5 to 50% of the people have antibodies against HTLV-1 antigens. (bvsalud.org)
  • Antibodies directed against white blood cell (WBC) human leukocyte antigen (HLA) in otherwise compatible donor blood are one possible cause. (merckmanuals.com)
  • AHTR usually results from recipient plasma antibodies to donor RBC antigens. (merckmanuals.com)
  • Antibodies against blood group antigens other than ABO can also cause AHTR. (merckmanuals.com)
  • Antibodies reactive with HIV ANTIGENS . (lookformedical.com)
  • Antibodies that reduce or abolish some biological activity of a soluble antigen or infectious agent, usually a virus. (lookformedical.com)
  • This study aimed to assess the seroprevalence and correlates of HBV, HCV, HDV, and HTLV 1&2 antibodies among MSM in Ouagadougou, Burkina Faso. (biomedcentral.com)
  • Anti-HTLV 1&2 antibodies were found in 4.0% (95% CI: 2.3-6.8) of MSM. (biomedcentral.com)
  • Presence of anti-HTLV 1&2 antibodies was associated with history of genital or anal lesions and injection drug use. (biomedcentral.com)
  • This study aimed to assess the seroprevalence and correlates of hepatitis B, C and D virus and anti-HTLV 1&2 antibodies among MSM, a high-risk population in Burkina Faso. (biomedcentral.com)
  • HTLV-II participants had significantly increased incidences of acute bronchitis (incidence ratio [IR] = 1.68), bladder or kidney infection (IR = 1.55), arthritis (IR = 2.66), and asthma (IR = 3.28), and a borderline increase in pneumonia (IR = 1.82, 95% confidence interval [CI] 0.98 to 3.38). (cdc.gov)
  • HTLV-I participants had significantly increased incidences of bladder or kidney infection (IR = 1.82), and arthritis (IR = 2.84). (cdc.gov)
  • We conclude that HTLV-II infection may inhibit immunologic responses to respiratory infections and that both HTLV-I and -II may induce inflammatory or autoimmune reactions. (cdc.gov)
  • Other possible health outcomes of chronic HTLV-I and -II infection have not yet been adequately investigated. (cdc.gov)
  • Patients with adult T-cell leukemia may develop opportunistic infections such as Pneumocystis carinii pneumonia ( 6 ) or Strongyloides superinfection ( 7 ) , but clinical immunodeficiency does not appear to develop in most persons with chronic HTLV-I or -II infection. (cdc.gov)
  • We have prospectively followed a large cohort of former blood donors with well-documented HTLV-I and -II infection at enrollment, and a similar group of uninfected donors, all of whom are HIV seronegative. (cdc.gov)
  • Until recently, the only reliable way to differentiate HTLV-I from HTLV-II infection was by polymerase chain reaction (7). (cdc.gov)
  • HTLV-I infection is endemic in southwestern Japan (10), the Caribbean basin (11), Melanesia (12), and in parts of Africa (13-15). (cdc.gov)
  • In some areas where HTLV-I infection is endemic, prevalence rates as high as 15% have been reported in the general population. (cdc.gov)
  • Since the JHK-3 cell line also contains Epstein-Barr virus DNA and nuclear antigen and a 196-nm viral particle of unusual morphology, this particle will be identified and its relationship determined, if any, to JHK viral infection. (ncf-net.org)
  • Moreover, The use of animals as surrogate rine host, can provide a platform for animal models for tumour viruses in hosts for the study of human tu- in vivo infection. (who.int)
  • Rickinson, A.B. and Moss, D.J. (1997) Human Cytotoxic T Lymphocyte Responses to Epstein-Barr Virus Infection. (scirp.org)
  • The life cycle of retroviruses is arbitrarily divided into two distinct phases: the early phase refers to the steps of infection from cell binding to the integration of the viral cDNA into the cell genome, whereas the late phase begins with the expression of viral genes and continues through to the release and maturation of progeny virions (see Figure 1 for a schematic view of the retroviral life cycle). (biomedcentral.com)
  • Human T-lymphotropic virus types I and II (HTLV-I and -II) are presumed to have derived from primate T-lymphotropic viruses with which they share significant nucleotide sequence homology ( 1 ) . (cdc.gov)
  • The human T-lymphotropic viruses, type I (HTLV-I) and type II (HTLV-II), are closely related but distinct retroviruses that can infect humans. (cdc.gov)
  • They are different from the human immunodeficiency viruses that cause acquired immunodeficiency syndrome. (cdc.gov)
  • Human T-lymphotropic viruses, type I (HTLV-I) and type II (HTLV-II), were the first human retroviruses discovered (1,2). (cdc.gov)
  • They are only distantly related to the human immunodeficiency viruses (HIV-1 and HIV-2), which belong to the lentivirus subfamily of retroviruses and which cause acquired immunodeficiency syndrome (AIDS). (cdc.gov)
  • Since several animal RNA tumor viruses (Klein 1980) and cells of the putative human retroviruses isolated to date (Bronson et al. (science-connections.com)
  • Four types of human T cell lymphotropic viruses (HTLV) have been described (HTLV-1 to HTLV-4) with three of them having closely related simian virus analogues named STLV-1, -2, and -3. (bvsalud.org)
  • In relation to "CFS", the most-studied viruses have been the Epstein-Barr Virus (EBV) and the Human Herpes Virus-6 (HHV-6). (investinme.org)
  • Proteins synthesized by HUMAN IMMUNODEFICIENCY VIRUSES such as the HIV-1 and HIV-2 . (lookformedical.com)
  • Men who have sex with men (MSM) are considered to be at significant risk for sexually transmitted infections (STI) and bloodborne viruses including viral hepatitis types B, C, and D (HBV, HCV, and HDV) and human T-cell leukemia virus types 1 and 2 (HTLV 1&2). (biomedcentral.com)
  • One exception is hu- humanized SCID mice, the use of al oncogenic viruses that are strictly man T-cell lymphotropic virus type 1 surrogate hosts has not proven very species-specific, causing cancer in (HTLV-1): in addition to its ability to useful for defining tumour site con- humans only. (who.int)
  • Animal models for human tumour mental animals is not easy to answer does induce adult T-cell leukaemia/ viruses that make use of animal virus- for these agents, because cancer bi- lymphoma (ATLL), albeit in monkeys es are scarce. (who.int)
  • For other human tumour virus- primate species are related to the hu- tween data in humans and in experi- es, the use of humanized severe man tumour viruses, the incidence of mental animals is not obvious. (who.int)
  • Human Coronaviruses and Other Respiratory Viruses: Underestimated Opportunistic Pathogens of the Central Nervous System? (mdpi.com)
  • Respiratory viruses infect the human upper respiratory tract, mostly causing mild diseases. (mdpi.com)
  • The common influenza viruses have antigens that mutate or combine readily, requiring new vaccines with each mutation. (unboundmedicine.com)
  • The 400 known viruses are classified in several ways: by genome core (RNA or DNA), host (animals, plants, or bacteria), method of reproduction (such as retrovirus), mode of transmission (such as enterovirus), and disease produced (such as hepatitis virus). (unboundmedicine.com)
  • The majority of emerging infectious diseases in humans are of animal origin, and many of them are caused by neuropathogenic viruses. (biomedcentral.com)
  • Retroviruses are single-stranded positive-sense RNA viruses that incorporate their genomes as proviruses into host chromosomal genomes after reverse transcription to cDNA. (biomedcentral.com)
  • Human T-cell leukemia/lymphoma virus type 1 (HTLV-1) was the first oncogenic human retrovirus discovered in 1980. (bvsalud.org)
  • For instance, mice are able to reconstitute most lymphomas in monkeys and humans woodchuck hepatitis virus induces major components of the human provides strong support for a direct hepatocellular carcinoma (HCC) haematolymphoid system including oncogenic role of EBV in vivo. (who.int)
  • McLaughlin-Drubin, M.E. and Munger, K. (2009) Oncogenic Activities of Human Papillomaviruses. (scirp.org)
  • In the United States, HTLV-I/II seroprevalence rates among volunteer blood donors average 0.016% (6). (cdc.gov)
  • HTLV-1 seroprevalence increases with age, especially in women. (bvsalud.org)
  • Nora Chapman et al from the Enterovirus Research Laboratory, Department of Pathology and Microbiology, University of Nebraska Medical Centre, have shown that human enteroviruses Coxsackie B can naturally delete sequence from the 5' end of the RNA genome and that this deletional mechanism results in long-term viral persistence, which has substantially altered the previously held view (http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2440640/?tool=pubmed). (investinme.org)
  • DNA sequences that form the coding region for the viral envelope (env) proteins in retroviruses. (lookformedical.com)
  • The battle against human viral infections has historically relied on two medical strategies, namely vaccines to protect from contagion and antivirals to treat infected patients. (infezmed.it)
  • Elucidating these mechanisms and identifying which cellular factors are exploited by the retroviruses and which hinder their life cycle, will certainly lead to the discovery of new ways to inhibit viral replication and to improve retroviral vectors for gene transfer. (biomedcentral.com)
  • Retroviruses that have integrated into the germline ( PROVIRUSES ) that have lost infectious capability but retained the capability to transpose. (lookformedical.com)
  • Introduction: tropical Spastic Paraparesis or HTLV-associated Myelopathy (HAM/TSP) is a chronic infectious and inflammatory disease that can interfere with various aspects of individuals life and, thereby alter their Quality of Life (QoL). (bvsalud.org)
  • so far, however, only the human retroviruses human immunodeficiency virus (HIV) and human T-cell lymphotrophic virus type I (HTLV-I), the simian retroviruses, and coxsackievirus B have been etiologically connected with the disease. (medscape.com)
  • More than 20 million people are infected by HTLV 1&2 worldwide, and West Africa is considered a highly endemic area [ 23 ]. (biomedcentral.com)
  • While human T-lymphotropic virus type 1 (HTLV-1) originates from ancient cross-species transmission of simian T-lymphotropic virus type 1 (STLV-1) from infected nonhuman primates, much debate exists on whether the first HTLV-1 occurred in Africa, or in Asia during early human evolution and migration. (bvsalud.org)
  • For this reason, the infect humans, this virus can infect cordance between humans and ex- question about tumour site concor- several other species - including perimental animals. (who.int)
  • testing, after amplification by polymerase chain reaction, indicated that approximately half were infected with HTLV-I and half with HTLV-II (6). (cdc.gov)
  • Because the polymerase chain-reaction test is not routinely available, many donors and other persons positive by serologic assays have been told that they are infected with HTLV-I/II. (cdc.gov)
  • HTLV-I has been causally associated with adult T-cell leukemia and HTLV-associated myelopathy. (cdc.gov)
  • HTLV-II has also been associated with HTLV-associated myelopathy, but not with leukemia ( 5 ) . (cdc.gov)
  • This study is a prospective, multicenter cohort of persons with HTLV-I and -II infections, which were detected at the time of attempted blood donation at five U.S. blood centers and comparable HTLV-seronegative donors. (cdc.gov)
  • Screening of the U.S. blood supply for HTLV-I/II, which began in 1988, identifies HTLV-I- and HTLV-II-infected persons who should be counseled regarding their infections. (cdc.gov)
  • Infections with HTLV-I and HTLV-II are most easily detected serologically. (cdc.gov)
  • The uncertainty regarding the identity of the infecting virus and the differing epidemiologic and clinical correlates of HTLV-I and HTLV-II infections have complicated counseling of HTLV-I/II-infected persons. (cdc.gov)
  • Serum specimens obtained were tested for the presence of HBV, HCV, HDV and HTLV-1&2 infections. (biomedcentral.com)
  • The virus is harmless to macaques or may cause only a herpetic rash in macaques, but in humans it often produces fatal infections of the brain and meninges. (unboundmedicine.com)
  • In addition, HML6_3p21.31c showed significant co-expression with cytokine binding and genes involved in EBV, HTLV-1 and HIV type-1 infections. (westminster.ac.uk)
  • It is estimated that around 10-20 million people are infected with HTLV-1 worldwide. (bvsalud.org)
  • Investigators in Japan have linked HTLV-I to a higher occurrence of various medical conditions ( 13 ) and virus-associated malignancies ( 14 ) . (cdc.gov)
  • A novel retrovirus, human T -celllymphomaleukemia virus (HTLV), has been isolated from the fresh and cultured cells of two of these patients. (science-connections.com)
  • Subsequent characterization of this virus has shown that it is not significantly related to any known animal retrovirus, is not an endogenous (genetically transmitted) virus of man, and so far has been associated only with fresh or cultured T -cells from patients with T -cell neoplasia. (science-connections.com)
  • However, HTLV-1 is not a ubiquitous virus. (bvsalud.org)
  • The following is a direct quotation from the CRISP search: ' Abstract Grant Number: 3RO1A132710-0353 PI Name: Grossberg, Sidney E. PI Title Project Title: JHK VIRUS Abstract: our goal is to determine by morphologic, genetic, biochemical, and immulogic means whether the JHK virus, an enveloped virus, and enveloped, 80-nm, RNA virus produced constitutively by a B lymphoblastoid cell line established in our laboratory, is a new human retrovirus. (ncf-net.org)
  • The salient features of our putative new virus must be compared with those of known retroviruses. (ncf-net.org)
  • CD4+ T-cells and other lymphocyte subsets in persons infected with human immunodeficiency virus (HIV). (cdc.gov)
  • 1997 revised guidelines for performing CD4+ T-cell determinations in persons infected with human immunode- ficiency virus [HIV]. (cdc.gov)
  • Single-platform technology (SPT) is designed to enable de- system and managing the health care of persons infected with terminations of both absolute and percentage lymphocyte sub- human immunodeficiency virus (HIV) ( 1-4 ). (cdc.gov)
  • Dalakas 2006 suggests that a chain of events causes IBM -- some sort of virus, likely a retrovirus , triggers the cloning of T cells . (wikidoc.org)
  • Resistance assays fall into two classes: genotyping examines the virus for mutations known to confer drug resistance, whereas phenotyping tests the susceptibility of the patient's virus to specific medications. (health.am)
  • External envelope protein of the human immunodeficiency virus which is encoded by the HIV env gene. (lookformedical.com)
  • Transmembrane envelope protein of the HUMAN IMMUNODEFICIENCY VIRUS which is encoded by the HIV env gene. (lookformedical.com)
  • Hepatitis C virus antigens enzyme immunoassay for one-step diagnosis of hepatitis C virus coinfection in human immunodeficiency virus infected individuals. (uc.edu)
  • The causative agent of ATLL has been identified as the human T cell lymphotropic virus type 1 (HTLV-1) [ 2 - 4 ], which is endemic to Japan, the Caribbean islands, Central and South America, and parts of sub-Saharan Africa [ 5 ]. (oncotarget.com)
  • ATLL develops in approximately 5% of HTLV-1 infected individuals who acquire the virus via vertical transmission [ 5 ]. (oncotarget.com)
  • These in vitro, and their expression in these human tumour virus. (who.int)
  • Hoang, H., Akihiro, T. and Norifumi, K. (2014) Role of Hepatitis B Virus DNA Integration in Human Hepatocarcinogenesis. (scirp.org)
  • Also that same year, I remember our high school biology class--this was advanced biology, Biology 2--sent away to the American Type Culture Collection for some Rous sarcoma virus. (nih.gov)
  • Livestock also act as transitory hosts that are intermediate between wildlife and humans, for example in the case of Nipah virus in Malaysia [ 6 , 7 ]. (biomedcentral.com)
  • The human immunodeficiency virus is an organism known as a retrovirus. (hivtalk.net)
  • Human immunodeficiency virus is a blood-borne virus typically transmitted via sexual intercourse, shared intravenous drug paraphernalia, and mother-to-child transmission , which can occur during the birth processor during breastfeeding. (hivtalk.net)
  • However, while the late stages of the retrovirus life cycle, consisting of virus replication and egress, have been partly unraveled, the early steps remain largely enigmatic. (biomedcentral.com)
  • The surge in Human Immunodeficiency Virus (HIV) research in order to identify new therapeutic targets has led to a better understanding of the retroviral life cycle. (biomedcentral.com)
  • Whether HTLV-II is associated with other diseases is unknown. (cdc.gov)
  • WHO stated that 23% of affected children with MIS-C had underlying conditions like chronic lung diseases, cardiovascular disease, and immunosuppression. (infezmed.it)
  • People who are overweight or obese run an increased risk of developing health problems later in life such as type 2 diabetes and cardiovascular diseases, or even certain cancers, which lead to disability and premature death. (institutcochin.fr)
  • Using survival analysis, we studied medical history data from a prospective cohort of HTLV-I- and HTLV-II-infected and -uninfected blood donors, all HIV seronegative. (cdc.gov)
  • A total of 152 HTLV-I, 387 HTLV-II, and 799 uninfected donors were enrolled and followed for a median of 4.4, 4.3, and 4.4 years, respectively. (cdc.gov)
  • Approximately half of HTLV-I/II-seropositive blood donors nationwide are infected with HTLV-I. HTLV-I-infected donors most often report a history of birth in HTLV-I-endemic countries or sexual contact with persons from the Caribbean or Japan. (cdc.gov)
  • In previous studies from this laboratory "activated" (by lectins) lymphoblasts from either peripheral blood or bone marrow from normal human donors were grown continuously with TCGF. (science-connections.com)
  • iv) reverse transcriptase: (v) infectivity for various somatic cells and (vi) reactivity with serum from J.H. and selected patients in order to help determine its possible role in humans disease. (ncf-net.org)
  • The abstract below was the same one asked for by Hillary Johnson, author of Osler's Web: Inside the Labyrinth of Chronic Fatigue Syndrome under an FOIA (Freedom of Information Act). (ncf-net.org)
  • In contrast to normal T -cells, neoplastic mature T -cells respond directly to TCGF, requiring no prior lectin or antigen in vitro activation. (science-connections.com)
  • We compared the effects of various spike (S) protein mutations in SARS-CoV-2 and its VOC on transmissibility, illness severity, hospitalization risk, fatality rate, immunological evasion, and vaccine efficacy in this review. (infezmed.it)
  • A second objective of this project will be to establish a prediction algorithm capable of assessing the functional impact of mutations in the obesity-related GPCR found in humans. (institutcochin.fr)
  • In November 1988, the Food and Drug Administration (FDA) recommended that blood donation centers screen the U.S. blood supply for HTLV-I (3). (cdc.gov)
  • This panel is geared to assess the underlying imbalances in neurotransmitters found in common chronic inflammatory conditions. (flimc.com)
  • Multisystem Inflammatory Syndrome in Children (MIS-C), a rare condition, has been reported approximately 2-4 weeks after the onset of COVID-19 in children and adolescents, causing inflammation in multiple systems, including cardiovascular and respiratory, digestive, and central nervous systems. (infezmed.it)
  • It is transmitted to humans by the mosquito or tick bite and is implicated in some cases of encephalitis. (unboundmedicine.com)
  • Many cases of neurological disease and encephalitis in livestock remain etiologically unresolved, posing a constant threat to animal and human health. (biomedcentral.com)
  • Using high-throughput sequencing (HTS) and bioinformatics, we discovered a new retrovirus, bovine retrovirus CH15 (BoRV CH15), in the CNS of a cow with non-suppurative encephalitis. (biomedcentral.com)
  • Indeed, HTLV-1 is present throughout the world with clusters of high endemicity including mainly southern Japan, the Caribbean region, parts of South America and intertropical Africa, with foci in the Middle East and Australia. (bvsalud.org)
  • In Sub-Saharan Africa, very few data exist on hepatitis B, C, and D as well as on HTLV 1&2 epidemiology among MSM. (biomedcentral.com)
  • During the long journey from the cell surface to the nucleus, retroviruses will face multiple obstacles, since in addition to finding a path through the cytoplasm to the nucleus they have to cross two main barriers, the plasma and nuclear membranes, whilst at the same time avoiding or counteracting cellular defences that can interfere with many of these steps. (biomedcentral.com)
  • In December 2019, the severe acute respiratory syndrome 2 (SARS-CoV-2) coronavirus outbreak began in Wuhan, China, and quickly spread to practically every corner of the globe, killing millions of people. (infezmed.it)
  • that is histopathological y very simi- T cel s, B cel s, natural kil er cel s, LMP1 of EBV can transform ro- lar to that caused by hepatitis B vi- macrophages, and dendritic cells, dent fibroblasts and is expressed rus (HBV) in humans, but it does so and this humanized mouse model in most of the human cancers as- through a different mechanism. (who.int)
  • It would seem reasonable then to survey human T -cell malignancies for the presence of retroviruses. (science-connections.com)
  • If the evidence obtained substantiates its novelty, additional goals will include exploring in depth its biology and molecular genetics and establishing its possible relationship to human disease, especially chronic fatigue immune deficiency syndrome (CFIDS), leukemia, and lymphoma. (ncf-net.org)
  • B-cell antigens are expressed on the immature cells that make up the tumor in virtually all cases of Burkitt lymphoma. (lookformedical.com)
  • Extranodal lymphoma of lymphoid tissue associated with mucosa that is in contact with exogenous antigens. (lookformedical.com)
  • Due to the close contact between farm animals and humans, pathogens are easily transmitted between these hosts. (biomedcentral.com)
  • In 1866, Kussmaul and Maier reported the case of a 27-year-old man who, over a period of approximately 2 months, developed a multisystem disease characterized by fever, myalgias, abdominal pain, mononeuritis multiplex, and proteinuria. (medscape.com)
  • In people with sIBM, the muscle cells display "flags" telling the immune system that they are infected or damaged (the muscles ubiquitously express MHC class I antigens) and this immune process leads to the death of muscle cells. (wikidoc.org)
  • Immune activation: A link between food insecurity and chronic disease in people living with HIV. (uc.edu)
  • In contrast, classical immune (type I/ II) cytokine receptors do not have intrinsic protein kinase activity but associate with the Janus family of kinases (JAKs). (openrheumatologyjournal.com)
  • For several of the human tu- and various assays demonstrated an sues. (who.int)
  • This document summarizes current information about HTLV, types I and II, and presents recommendations developed by CDC and a U.S. Public Health Service working group for counseling HTLV-I- and HTLV-II-infected persons. (cdc.gov)
  • The recommendations for counseling HTLV-I-, HTLV-II-, and HTLV-I/II-infected persons included in this document are intended for use by health-care workers and public health officials in the United States. (cdc.gov)
  • Since 1992, the term "Chronic Fatigue Syndrome" (CFS) has been included in the Alphabetical Index and indexed to G93.3. (investinme.org)
  • Haller, K., Stubenrauch, F. and Pfister, H. (1995) Differentiation-Dependent Transcription of the Epidermodysplasia Verruciformis-Associated Human Papillomavirus Type 5 in Benign Lesions. (scirp.org)
  • Despite the roughly 60 type I/II cytokines discovered, there are only four members in the JAK kinase family. (openrheumatologyjournal.com)
  • The elaboration of immunoglobulins and presence of receptors for EBV are most characteristic of human B-cells. (science-connections.com)
  • Case series and cross-sectional studies of HTLV-I and -II disease outcomes are vulnerable to potential bias and confounding. (cdc.gov)
  • In IBM, two processes appear to occur in the muscles in parallel, one autoimmune and the other degenerative. (wikipedia.org)
  • In sporadic inclusion body myositis [MY-oh-sigh-tis] muscle, two processes, one autoimmune and the other degenerative, appear to occur in the muscle cells in parallel. (wikidoc.org)
  • Dalakas 2006, says "we can say that two processes, one autoimmune and the other degenerative, occur in the muscle cells in parallel. (wikidoc.org)
  • 1975) have required the establishment of continuously growing cell lines from the disease of origin or cocultivation of these cells with previously established cell lines, the ability to grow malignant T -cells in long-term culture could facilitate the isolation of retroviruses from these diseased states. (science-connections.com)
  • Allogeneic transplantation was performed in five patients, two of whom achieved complete remission despite residual or refractory disease. (oncotarget.com)
  • the disease caused by the cognate cel s from human cord blood. (who.int)
  • These results suggest that HTLV infected some mature T -cells of some people and that it might be involved in some neoplasias involving these cells. (science-connections.com)
  • Although there are many immunologic and cytochemical differences between mature hu man T- and B-Iymphocytes, human T -cells are primarily distinguished by their participation in cell mediated immunity and possession of receptors for sheep red blood cells. (science-connections.com)
  • T-cell numbers were derived from three measurements deter- attributable to the decrease in the number of T cells that bear mined with two different instruments, a hematology analyzer the CD4 receptor ( 5-9 ). (cdc.gov)
  • The inflammation aspect is characterized by the cloning of T cells that appear to be driven by specific antigens to invade muscle fibers. (wikidoc.org)
  • These T cells appear to be driven by specific antigens to invade muscle fibers. (wikidoc.org)