• Risk Factors
  • Depression and high-fat diet are both known as independent risk factors for atherosclerosis and other cardiovascular diseases, suggesting the interaction of psychological and physiological factors in the development of these diseases. (biomedcentral.com)
  • Heterozygous familial hypercholesterolemia in pediatric patients Homozygous familial hypercholesterolemia Hypertriglyceridemia (Fredrickson Type IV) Primary dysbetalipoproteinemia (Fredrickson Type III) Combined hyperlipidemia Primary prevention of heart attack, stroke, and need for revascularization procedures in patients who have risk factors such as age, smoking, high blood pressure, low HDL-C, and a family history of early heart disease, but have not yet developed clinically evident coronary heart disease. (wikipedia.org)
  • lipid
  • These observations suggested that chronic psychological stress alone is virtually propitious to lipid metabolism, however when under a condition of high-fat diet, it deteriorated atherosclerotic plague and did harm to RCT. (biomedcentral.com)
  • Higher doses were more efficacious in improving the lipid profile of patients with hypercholesterolemia than milligram-equivalent doses of atorvastatin and milligram-equivalent or higher doses of simvastatin and pravastatin. (wikipedia.org)
  • Clinical
  • The severity of Parkinson's Disease symptoms changes faster than researchers thought, so clinical trials should be designed differently. (patientslikeme.com)
  • Geriatric: Plasma concentrations of atorvastatin in healthy elderly subjects are higher than those in young adults, and clinical data suggests a greater degree of LDL-lowering at any dose for patients in the population as compared to young adults. (wikipedia.org)
  • hyperglycemia
  • It is caused in part by prolonged hyperglycemia (high blood sugar) and results in dysfunction of one or both tibial nerves and a plantigrade stance (down on the hocks). (wikipedia.org)
  • hepatic
  • This in turn may lead to a number of symptoms or complications: Fluid retention in the abdomen (ascites) in more advanced disease Enlarged spleen in more advanced disease Oesophageal varices in more advanced disease Hepatic encephalopathy, including coma in extreme cases in more advanced disease. (wikipedia.org)
  • Hepatic impairment: In patients with chronic alcoholic liver disease, levels of atorvastatin may be significantly increased depending upon the extent of liver disease. (wikipedia.org)
  • atherosclerotic
  • 1 This guideline presented significant changes to previous recommendations on the management of hyperlipidemia for primary and secondary prevention of atherosclerotic cardiovascular disease (ASCVD), which includes acute coronary syndrome, stable or unstable angina, coronary or other arterial revascularization, stroke, transient ischemic attack, and peripheral arterial disease presumed to be of atherosclerotic origin. (aafp.org)
  • Depression
  • For instance, it was shown that metabolic syndrome was associated with long-term depressive symptoms, while another study reported absence of any correlation between metabolic syndrome, depression and anxiety. (biomedcentral.com)
  • citation needed] Identifying BD in youth is challenging because, while adults with BD often have distinct periods of depression and mania that last for weeks, months, or longer, youth diagnosed with BD frequently have depressive and manic symptoms that occur daily, and sometimes simultaneously either as rapid shifts or periods of high energy negative mood. (wikipedia.org)
  • levels
  • Cushing syndrome occurs due to abnormally high levels of cortisol. (aarpmedicareplans.com)
  • The tumor may be nonfunctioning (does not produce hormones) or functioning in which case excessive levels of hormones can cause a variety of symptoms depending on which hormone is involved. (wrongdiagnosis.com)
  • Low level of HDL is associated with increased risk of heart disease whereas High levels of HDL levels seem to be protective against heart disease. (medindia.net)
  • Produced in high levels during periods of stress, infection, etc possibly leading to diabetic ketoacidosis, a very serious condition. (wikipedia.org)
  • Putative beneficial effects of rosuvastatin therapy on chronic heart failure may be negated by increases in collagen turnover markers as well as a reduction in plasma coenzyme Q10 levels in patients with chronic heart failure. (wikipedia.org)
  • The results of the JUPITER trial (2008) suggested rosuvastatin may decrease the relative risk of heart attack and stroke in patients without hyperlipidemia, but with elevated levels of highly sensitive C-reactive protein. (wikipedia.org)
  • primary
  • Patients with a high risk of ASCVD (a 10-year risk of at least 7.5% or 10%, depending on the guideline) should receive statin therapy for primary prevention. (aafp.org)
  • To diagnose PBC, it needs to be distinguished from other conditions with similar symptoms, such as autoimmune hepatitis or primary sclerosing cholangitis (PSC). (wikipedia.org)
  • insulin
  • When the body produces insulin under conditions of insulin resistance, the cells are resistant to the insulin and are unable to use it as effectively, leading to high blood sugar. (wikipedia.org)
  • Beta cells in the pancreas subsequently increase their production of insulin, further contributing to a high blood insulin level. (wikipedia.org)
  • Although this type of chronic insulin resistance is harmful, during acute illness it is actually a well-evolved protective mechanism. (wikipedia.org)
  • occur
  • When not associated with a raccoon bite, the same symptoms occur, with the paresis taking about 3-4 days to reach its maximum effect. (wikipedia.org)
  • Atherosclerosis
  • The effects of intravenous injection of Porphyromonas gingivalis (Pg) on rabbit inflammatory immune response and atherosclerosis were evaluated by establishing a microamount Pg bacteremia model combined with high-fat diet. (hindawi.com)
  • prone
  • Adults with uncorrected genu valgum are typically prone to injury and chronic knee problems such as chondromalacia and osteoarthritis. (wikipedia.org)
  • tolerate
  • Patients with known ASCVD should receive high-intensity statins unless they fall into special categories (e.g., older age) or do not tolerate high-intensity statins, in which case moderate-intensity statins are appropriate. (aafp.org)
  • diet
  • This study provided evidence that high-fat diet greatly decreased these genes expression related to RCT while chronic stress alone tended to promote RCT. (biomedcentral.com)
  • inflammation
  • Liver disease with extensive inflammation and a high degree of steatosis often progresses to more severe forms of the disease. (wikipedia.org)
  • Reduction
  • Gender: Plasma concentrations are generally higher in women than in men, but there is no clinically significant difference in the extent of LDL reduction between men and women. (wikipedia.org)
  • include
  • Symptoms in dogs include acute arthritis, anorexia and lethargy. (wikipedia.org)
  • Symptoms include decreased or absent reflexes and muscle tone, weakness, or paralysis. (wikipedia.org)
  • Distal symmetric polyneuropathy symptoms include atrophy of the distal leg muscles and the muscles of the head, and rear limb weakness. (wikipedia.org)
  • Symptoms usually start between the ages of 7 and 10 weeks, and include weakness, decreased reflexes, and loss of bark. (wikipedia.org)
  • When associated with a raccoon bite, the symptoms start 7 to 11 days after the bite, and include rear leg weakness progressing rapidly to paresis, and decreased reflexes. (wikipedia.org)
  • Infection
  • In medicine, a disease is considered asymptomatic if a patient is a carrier for a disease or infection but experiences no symptoms. (wikipedia.org)
  • hereditary
  • If symptoms are prolonged and pronounced or hereditary, doctors often use orthotic shoes or leg braces at night to gently move a child's leg back into position. (wikipedia.org)