• Homo
  • Homo sapiens remained restricted to Africa and the Middle East until about 60,000 - 70,000 years ago, when a relatively small group of humans departed from eastern Africa across the mouth of the Red Sea and migrated into Asia and Europe. (brainscape.com)
  • Modern humans (Homo sapiens, ssp. (wikipedia.org)
  • Early hominins-particularly the australopithecines, whose brains and anatomy are in many ways more similar to ancestral non-human apes-are less often referred to as "human" than hominins of the genus Homo. (wikipedia.org)
  • In common usage, the word "human" generally refers to the only extant species of the genus Homo-anatomically and behaviorally modern Homo sapiens. (wikipedia.org)
  • The previously clear boundary between humans and apes has blurred, resulting in now acknowledging the hominids as encompassing multiple species, and Homo and close relatives since the split from chimpanzees as the only hominins. (wikipedia.org)
  • There is also a distinction between anatomically modern humans and Archaic Homo sapiens, the earliest fossil members of the species. (wikipedia.org)
  • Note that the Latin word homo refers to humans of either gender, and that sapiens is the singular form (while there is no such word as sapien). (wikipedia.org)
  • The genus Homo evolved and diverged from other hominins in Africa, after the human clade split from the chimpanzee lineage of the hominids (great apes) branch of the primates. (wikipedia.org)
  • In Homo sapiens, the CCDC142 gene encodes for two alternatively spliced isoforms of the mRNA, called isoform 1 and isoform 2. (wikipedia.org)
  • Deletion
  • The deletion occurs near the middle of the chromosome at a location designated as q11.2. (wikipedia.org)
  • 22q11.2 distal deletion syndrome 22q13 deletion syndrome Other chromosomal conditions: Other changes in the number or structure of chromosome 22 can have a variety of effects, including mental retardation, delayed development, physical abnormalities, and other medical problems. (wikipedia.org)
  • species
  • Vampires are one of the four known supernatural species in the Twilight series, with the others being vampire-human hybrids , true werewolves (also called Children of the Moon), and shapeshifters . (wikia.com)
  • The spread of humans and their large and increasing population has had a profound impact on large areas of the environment and millions of native species worldwide. (wikipedia.org)
  • Humans use tools to a much higher degree than any other animal, are the only extant species known to build fires and cook their food, and are the only extant species to clothe themselves and create and use numerous other technologies and arts. (wikipedia.org)
  • The native English term man can refer to the species generally (a synonym for humanity) as well as to human males, or individuals of either sex (though this latter form is less common in contemporary English). (wikipedia.org)
  • Biologists classify humans, along with only a few other species, as great apes (species in the family Hominidae). (wikipedia.org)
  • The immunological response of a species to its own antigens (e.g. human to human) was set to be 1. (wikipedia.org)
  • It is expected that by comparing the genomes of humans and other apes, it will be possible to better understand what makes humans distinct from other species from a genetic perspective. (wikipedia.org)
  • Orthologs were found in species as distantly related to Humans as the Choanoflagellate Monosiga brevicollis using BLAST and the ALIGN tool through the San Diego Super Computer Biology Workbench. (wikipedia.org)
  • modern humans
  • The origin and migration of modern humans can be documented with reasonable certainty with archeological, linguistic, & molecular genetic analysis. (brainscape.com)
  • In scientific terms, the meanings of "hominid" and "hominin" have changed during the recent decades with advances in the discovery and study of the fossil ancestors of modern humans. (wikipedia.org)
  • FOXP2
  • One such region on chromosome 7 contains the FOXP2 gene (mentioned above) and this region also includes the Cystic fibrosis transmembrane conductance regulator (CFTR) gene, which is important for ion transport in tissues such as the salt-secreting epithelium of sweat glands. (wikipedia.org)
  • temporal
  • In 1960, J. H. Taylor showed that the active and inactive X chromosomes replicate in a different pattern, with the active X replicating earlier than the inactive X, whereas all the other pairs of chromosomes replicate in the same temporal pattern. (wikipedia.org)
  • molecules
  • PILRA is thought to act as a cellular signaling inhibitory receptor by recruiting cytoplasmic phosphatases like PTPN6 /SHP-1 and PTPN11 /SHP-2 via their SH2 domains that block signal transduction through dephosphorylation of signaling molecules. (rcsb.org)
  • receptor
  • Human chorionic gonadotropin interacts with the LHCG receptor of the ovary and promotes the maintenance of the corpus luteum during the beginning of pregnancy. (wikipedia.org)
  • apes
  • The divergence time of humans from other apes is of great interest. (wikipedia.org)
  • However the distance to six different Old World monkeys was on average 2.46, indicating that the African apes are more closely related to humans than to monkeys. (wikipedia.org)
  • genomes
  • An example of such assembler Short Oligonucleotide Analysis Package developed by BGI for de novo assembly of human-sized genomes, alignment, SNP detection, resequencing, indel finding, and structural variation analysis. (wikipedia.org)
  • band
  • PURPOSE: Submicroscopic deletions of chromosome band 2p25.3 are associated with intellectual disability and/or central obesity. (forskningsdatabasen.dk)
  • Though most of human existence has been sustained by hunting and gathering in band societies, increasing numbers of human societies began to practice sedentary agriculture approximately some 10,000 years ago, domesticating plants and animals, thus allowing for the growth of civilization. (wikipedia.org)
  • Estimation of band level resolutions of human chromosome images" (PDF). (wikipedia.org)
  • PRR36 is located on the short arm of human chromosome 19 at 19p13.2 (region 1, band 3, and sub-band 2). (wikipedia.org)
  • chromosomal
  • Six human chromosomal regions were found that may have been under particularly strong and coordinated selection during the past 250,000 years. (wikipedia.org)
  • These regions contain at least one marker allele that seems unique to the human lineage while the entire chromosomal region shows lower than normal genetic variation. (wikipedia.org)
  • mice
  • In mice, the official symbol of M33 gene styled Cbx2 and the official name chromobox 2 are maintained by the MGI. (wikipedia.org)
  • region
  • Another such region on chromosome 4 may contain elements regulating the expression of a nearby protocadherin gene that may be important for brain development and function. (wikipedia.org)
  • found
  • The IntAct tool was also used, and this revealed a potential interaction had been found with Superoxide dismutase 2 (SOD2), which had been identified in a yeast Two-hybrid screening study. (wikipedia.org)
  • length
  • Replication timing refers to the order in which segments of DNA along the length of a chromosome are duplicated. (wikipedia.org)
  • These values (ISCN start/stop) are based on the length of bands/ideograms from the ISCN book, An International System for Human Cytogenetic Nomenclature (2013). (wikipedia.org)
  • It is 8,954 base pairs in length. (wikipedia.org)
  • The difference in length is made entirely by amino acids missing from the C-terminus of isoform 2. (wikipedia.org)
  • This promoter exists on the negative strand from position 7939226 to 7939826 and is 601 base pairs in length. (wikipedia.org)