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  • retain
  • Chick embryo fibroblasts infected with Rous sarcoma virus in vitro are rendered malignant for such cells produce typical Rous sarcomas when injected into susceptible chicks since the tumors produced predominantly retain the sex chromatin patterns of the donor cells when such cells are injected into a recipient of the opposite sex. (rupress.org)
  • Cultures in which sex chromatin persists also retain the viral insensitivity of their source material. (sciencemag.org)
  • occurs
  • We observed that UV-dependent DNA synthesis occurs simultaneously with chromatin assembly, strongly indicating a mechanistic coupling between the two processes. (cshl.edu)
  • human
  • To investigate whether the resetting of nucleosomal arrays can be linked to the repair process, we developed model systems, with both Xenopus egg extract and human cell extracts, to follow repair and chromatin assembly in parallel on circular DNA templates. (cshl.edu)
  • Biological
  • Written by leading, internationally renowned clinicians and basic scientists with expertise in sperm DNA, Sperm Chromatin: Biological and Clinical Applications in Male Infertility and Assisted Reproduction provides readers with a thoughtful and comprehensive review of the biological and clinical significance of sperm DNA damage. (springer.com)
  • Unlike any other title on the topic, Sperm Chromatin: Biological and Clinical Applications in Male Infertility and Assisted Reproduction is an invaluable addition to the literature and will serve as an indispensable resource for basic scientists with an interest in sperm biology and for urologists, gynecologists, reproductive endocrinologists, and embryologists working in the field of infertility. (springer.com)
  • NRL is an important physical chromatin property that determines its biological function. (wikipedia.org)
  • remodelers
  • Furthermore, it was reported that the NRL determined around yeast TSSs is an invariant value universal for a given wild type yeast strain, although it can change when one of chromatin remodelers is missing. (wikipedia.org)
  • mitosis
  • The primary functions of chromatin are 1) to package DNA into a more compact, denser shape, 2) to reinforce the DNA macromolecule to allow mitosis, 3) to prevent DNA damage, and 4) to control gene expression and DNA replication. (wikipedia.org)
  • As the daughter cells exit mitosis and re-enter interphase, the chromatin bridge becomes known as an interphase bridge. (wikipedia.org)
  • Chromatin bridges may form by any number of processes wherein chromosomes remain topologically entangled during mitosis. (wikipedia.org)
  • Structure
  • Likewise, chromatin structure is responsive to complicated manipulations by the cellular machinery that make the DNA more or less accessible for the transcriptional apparatus. (asbmb.org)
  • RNA transcription and chromatin structure during meiotic and postmeiotic stages of spermatogenesis. (springer.com)
  • Changes in chromatin structure during spermatogenesis in maturing rooster testis as demonstrated by the initiation pattern of ribonucleic acid synthesis in vitro. (springer.com)
  • jrbone at onramp.net voice: 713-792-2549 Roth Lab Homepage-- http://rampages.onramp.net/~jrbone/rothlab.htm Chromatin Structure & Function Page-- http://rampages.onramp.net/~jrbone/chrom.html 'The truths of organic nature are of a charming and awesome beauty. (bio.net)
  • For additional information, see Histone modifications in chromatin regulation and RNA polymerase control by chromatin structure. (wikipedia.org)
  • Z-DNA is thought to play a specific role in chromatin structure and transcription because of the properties of the junction between B- and Z-DNA. (wikipedia.org)
  • RSC (Remodelling the Structure of Chromatin) is a member of the ATP-dependent chromatin remodeller family (other members being the SWI/SNF, INO80, ISW1 and CHD complexes). (wikipedia.org)
  • For example, individual H1 variant knockout mice reveal specific phenotypes and distinct effects on gene expression and chromatin structure. (wikipedia.org)
  • Mechanisms
  • The image depicts six broad categories of chromatin regulatory mechanisms, which are all known to be altered via mutations in the pathogenesis of human cancer. (eurekalert.org)
  • interphase
  • During interphase, the chromatin is structurally loose to allow access to RNA and DNA polymerases that transcribe and replicate the DNA. (wikipedia.org)
  • methylation
  • Lysine tri-methylation can either be correlated with transcriptional activity (tri-methylation of histone H3 Lysine 4) or transcriptional repression and chromatin compaction (tri-methylation of histone H3 Lysine 9 or 27). (wikipedia.org)
  • nucleus
  • The chromatin is also responsible for helping transcribe RNA, help prevent the DNA from being damaged while being compacted inside the nucleus, and assist in gene expression. (reference.com)
  • typically
  • Salt-and-pepper chromatin is typically seen in endocrine tumours such as medullary thyroid carcinoma, neuroendocrine tumours and pheochromocytoma. (wikipedia.org)
  • bound
  • A chromatin bridge may also be observed using indirect immunofluorescence, in which anti-tubulin emits a green coloration when bound to microtubules in the presence of UV light. (wikipedia.org)
  • fundamental
  • The work covers the fundamental principles of sperm chromatin architecture and function, the proposed modes of DNA damage and repair, the tests of sperm DNA damage, the clinical aspects of DNA damage and the impact of DNA damage on reproductive outcome. (springer.com)
  • cell
  • Called live cell Partial Wave Spectroscopic (PWS) microscopy, the technique detects chromatin by using scattered light. (eurekalert.org)
  • Bivalent chromatin domains are found in embryonic stem (ES) cells and play an important role in cell differentiation. (wikipedia.org)
  • Once the cell has differentiated to a specific type of cell only one of the marks remain associated with the chromatin. (wikipedia.org)
  • cells
  • Because they require toxic fluorescent dyes to enhance contrast, previous techniques could not image chromatin in living cells without killing or perturbing the cells. (eurekalert.org)
  • Not only is the technique label-free, allowing researchers to study chromatin within unharmed, living cells, but it does so with high-throughput and at very low cost. (eurekalert.org)
  • Chromatin bridge is a mitotic occurrence that forms when telomeres of sister chromatids fuse together and fail to completely segregate into their respective daughter cells. (wikipedia.org)
  • The Xist chromatin binding region was first elucidated in female mouse fibroblastic cells. (wikipedia.org)
  • The chromatin-binding region was functionally mapped and evaluated by using an approach for studying noncoding RNA function in living cells called peptide nucleic acid (PNA) interference mapping. (wikipedia.org)