• thus
  • Cholesterol is one of three major classes of lipids which all animal cells use to construct their membranes and is thus manufactured by all animal cells. (wikipedia.org)
  • enzyme
  • The development of the corpus luteum is accompanied by an increase in the level of the steroidogenic enzyme P450scc that converts cholesterol to pregnenolone in the mitochondria. (wikipedia.org)
  • increase
  • According to the FDA, the risk of myopathy during rosuvastatin therapy may be increased in Asian Americans: Because Asians appear to process the drug differently, half the standard dose can have the same cholesterol-lowering benefit in those patients, though a full dose could increase the risk of side-effects, a study by the drug's manufacturer, AstraZeneca, indicated. (wikipedia.org)
  • protein
  • PKA actively phosphorylates steroidogenic acute regulatory protein (StAR) and translocator protein to transport cholesterol from the outer mitochondrial membrane to the inner mitochondrial membrane. (wikipedia.org)
  • steroid
  • The combination of a cholesterol-lowering drug, bezafibrate, and a contraceptive steroid, medroxyprogesterone acetate, could be an effective, non-toxic treatment for a range of cancers, researchers at the University of Birmingham have found. (wikipedia.org)
  • cell
  • Cholesterol is released and stored within the cell as cholesterol ester. (wikipedia.org)
  • This type of LDL is usually incorporated in macrophages, resulting in foam cell formation and formation of an atherosclerotic plaque which narrows or blocks the arteries. (wikipedia.org)
  • case
  • These compounds consist of an aglycon, which is a cholesterol derivative, and a carbohydrate chain, which in the case of α-tomatine consists of two d-glucose units, a d-galactose unit, and a d-xylose unit. (wikipedia.org)