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Myeloid leukemiaLymphoblasticMyelodysplasticMyelogenous leukemiaErythroidMonocytic leukemiaLymphocytic leukemiaPromyelocytic leukemiaCytoplasmChronic leukemiaMyelomonocyticRadiationRadiotherapyPatientsLineageAggressiveSurvivalRefractoryCancersInfectionInflammationTumorTreatmentRemissionHematopoieticMedicationsStemDisordersCellsMolecularInvolvesInclude
Myeloid leukemia12
  • Acute myeloid leukemia (AML) is a cancer of the myeloid line of blood cells, characterized by the rapid growth of abnormal cells that build up in the bone marrow and blood and interfere with normal blood cell production. (wikipedia.org)
  • Acute myeloid leukemia (AML) and related neoplasms. (oncolink.org)
  • Myeloid leukemia associated with Down syndrome. (oncolink.org)
  • These malignancies are further characterized by the maturity and differentiation of the individual cell types and are divided into acute leukemias such as acute myeloid leukemia and acute lymphoblastic leukemia and chronic leukemias such as chronic myeloid leukemia and chronic lymphocytic leukemia. (medscape.com)
  • Here, we describe an acute myeloid leukemia (AML) that progressed from myelodysplastic syndrome (MDS) in association with acquisition of 1q JTs. (biomedcentral.com)
  • Reportable disorder s include: MDS, refractory anemia , refractory anemia with excess blasts in transformation, refractory anemia with ring sideroblast s, refractory anemia with excess blasts, chronic myelomonocytic leukemia and acute myeloid leukemia. (symptoma.com)
  • Chronic myeloid leukemia ( CML ), BCR-ABL1-positive, is a myeloproliferative neoplasm (MPN) in which granulocyte s are the major proliferative component. (cancer.gov)
  • 5 Hematopoietic disruptions in the myeloid lineage can lead to 3 major disease categories: acute myeloid leukemia (AML), myeloproliferative neoplasms (MPN), and myelodysplastic syndrome (MDS). (oncomine.com)
  • 1,2 The 4 primary disorders of MPNs are chronic myeloid leukemia (CML), polycythemia vera (PV), essential thrombocythemia (ET), and primary myelofibrosis (PMF). (oncomine.com)
  • 12,13 They also have a high propensity to progress to acute myeloid leukemia (AML). (oncomine.com)
  • Characterized by excessive, abnormal white blood cell (granulocyte) production and the presence of the Philadelphia chromosome/BCR-ABL mutation, chronic myeloid leukemia (CML) is a slow-growing cancer of the blood-forming tissue (bone marrow). (oncomine.com)
  • Epigenetic modifying enzymes such as histone deacetylases (HDACs), p300, and PRMT1 are recruited by AML1/ETO, the pathogenic protein for t(8;21) acute myeloid leukemia (AML), providing a strong molecular rationale for targeting these enzymes to treat this disease. (ashpublications.org)
Lymphoblastic10
  • Relapsed acute lymphoblastic leukemia: Is it crucial to achieve molecular remission prior to transplant? (nih.gov)
  • Acute lymphoblastic leukemia (ALL) is the most common malignancy diagnosed in children, representing more than a quarter of all pediatric cancers. (medscape.com)
  • The image below depicts bone marrow aspirate from a child with T-cell acute lymphoblastic leukemia. (medscape.com)
  • Also, see the Childhood Acute Lymphoblastic Leukemia: Diagnosis, Management, and Complications slideshow to help recognize and treat this disease and its associated complications. (medscape.com)
  • Children with acute lymphoblastic leukemia (ALL) often present with signs and symptoms that reflect bone marrow infiltration and/or extramedullary disease. (medscape.com)
  • See Acute Lymphoblastic Leukemia Staging for more complete information. (medscape.com)
  • Global Acute Lymphocytic/Lymphoblastic Leukemia Therapeutics Market - The Global Acute Lymphocytic/Lymphoblastic Leukemia Therapeutics Market witnessed a rapid growth in the historic period from 2016 to 2019 and is anticipated to witness significant growth during the forecast period. (powershow.com)
  • Acute Lymphocytic / Lymphoblastic Leukemia Market - The acute lymphoblastic leukemia therapeutics market is segmented based on the existing regimens and drugs, pipeline drugs, and geography. (powershow.com)
  • Acute Lymphocytic/Lymphoblastic Leukemia Market worth $3.780.3 Million by 2020 - The "Acute Lymphocytic/Lymphoblastic Leukemia Therapeutics Market - (Pipeline Forecast & Market Forecast in G8 Countries) (2010 - 2020)" analyzes and studies the major market drivers, restraints, and opportunities in the U.S., Canada, U.K., France, Germany, Italy, Spain, and Japan. (powershow.com)
  • Following diagnosis and treatment as pre-B cell acute lymphoblastic leukaemia (pre-B ALL) the patient developed an acute myeloid leukaemia (AML) which was refractory to all available curative therapies. (cambridgemedicine.org)
Myelodysplastic3
  • Risk factors include smoking, previous chemotherapy or radiation therapy, myelodysplastic syndrome, and exposure to the chemical benzene. (wikipedia.org)
  • Decreased WBC count, leukopenia, is seen when supply is depleted by infection or treatment such as chemotherapy or radiation therapy, or when a hematopoietic stem cell abnormality does not allow normal growth/maturation within the bone marrow, such as myelodysplastic syndrome or leukemia. (medscape.com)
  • A reduced number of white blood cells can by caused by damaged or deficient bone marrow (toxins, chemotherapy, radiation, certain medications, myelodysplastic syndrome, vitamin B12 or folic acid deficiency, lymphoma or other cancer that has invaded the bone marrow). (biron.com)
Myelogenous leukemia1
  • Acute myelogenous leukemia (AML) is a blood cancer that affects white blood cells, red blood cells, and/or platelets. (oncolink.org)
Erythroid1
Monocytic leukemia2
Lymphocytic leukemia9
  • AML may also be called acute myelocytic leukemia, acute granulocytic leukemia, or acute non-lymphocytic leukemia. (oncolink.org)
  • Immunophenotyping by flow cytometry of bone marrow or peripheral blood samples can be used to help distinguish AML from acute lymphocytic leukemia (ALL) and further classify the subtype of AML. (medscape.com)
  • Acute Lymphocytic Leukemia Drug Pipeline Analysis and Therapeutic Assessment, H2 2016 - Global Markets Direct's latest Pharmaceutical and Healthcare disease pipeline guide Acute Lymphocytic Leukemia Pipeline Review, H2 2016, provides an overview of the Acute Lymphocytic Leukemia (Oncology) pipeline landscape. (powershow.com)
  • Global Markets Direct's latest Pharmaceutical and Healthcare disease pipeline guide Acute Lymphocytic Leukemia Pipeline Review, H2 2016, provides an overview of the Acute Lymphocytic Leukemia (Oncology) pipeline landscape. (powershow.com)
  • Acute Lymphocytic Leukemia Therapeutics Market worth $3.88 Billion by 2020 - The acute lymphocytic leukemia therapeutics market was valued at $1.96 billion in 2010 and is expected to reach $3.88 billion by 2020, at a CAGR of 5.21% between 2015 and 2020. (powershow.com)
  • The chemotherapy drug regimens were dominated by Hyper-CVAD regimen sales, totaling $1.8 billion and linker regimen sales totaling $1.13 billion sales in acute lymphocytic leukemia market. (powershow.com)
  • Global Acute Lymphocytic Leukemia Market: Trend Analysis and Forecast to 2022 - The report on Acute Lymphocytic Leukemia Market by Infinium Global Research analyzes over the period of 2015 to 2022. (powershow.com)
  • This report also provides detailed qualitative and quantitative analyses of the market dynamics, market size and future trends in Global Acute Lymphocytic Leukemia Market. (powershow.com)
  • It will help a lot of decision makers to develop strategies and find new opportunities in the Global Acute Lymphocytic Leukemia Market. (powershow.com)
Promyelocytic leukemia3
  • Cytogenetic studies performed on bone marrow provide important prognostic information and can guide treatment by confirming a diagnosis of acute promyelocytic leukemia (APL). (medscape.com)
  • Acute promyelocytic leukemia (APL), also known as M3, is the most common subtype of AML associated with DIC. (medscape.com)
  • Prompt Initiation of Conventional Chemotherapy to Avoid Early Death in Patients with Newly Diagnosed Acute Promyelocytic Leukemia. (u-tokyo-hemat.com)
Cytoplasm3
  • 5-7 Morphologically, BL involves monomorphic medium-sized B cells with basophilic cytoplasm, numerous mitotic figures, rounded nuclei with finely clumped chromatin, myriad apoptosis, and tingible body macrophages, which result in a classic "starry sky" pattern. (cancernetwork.com)
  • These blasts were large with basophilic cytoplasm and no granulation. (cambridgemedicine.org)
  • BL is characterized by monomorphic medium-sized B cells with basophilic cytoplasm and numerous mitotic figures [ 3 , 4 ]. (longdom.org)
Chronic leukemia1
Myelomonocytic3
Radiation2
  • People may then go on to receive additional chemotherapy, radiation therapy, or a stem cell transplant. (wikipedia.org)
  • Although the incidence of acute nonlymphocytic leukemia is increased in PV, the incidence of acute leukemia in patients not exposed to chemotherapy or radiation therapy is low. (basicmedicalkey.com)
Radiotherapy3
  • Where a defined exposure to past chemotherapy, radiotherapy, toxin or hematologic malignancy is known, this is termed secondary AML. (wikipedia.org)
  • Current treatment methods for lung cancer are mostly traditional methods, including surgery, chemotherapy, and radiotherapy. (immune-source.com)
  • In the latest years, people discovered that there is certainly a little subpopulation of cells in tumors, which play a essential function in the resistance of cancer to radiotherapy and chemotherapy. (immune-source.com)
Patients6
  • In recent years, the frequency of opportunistic fungal infections has increased in parallel with the growing number of patients receiving aggressive chemotherapy ( 1 , 2 ). (cdc.gov)
  • 90% of reported cases is prolonged and profound neutropenia in patients with acute leukemia ( 6 , 7 , 9 ). (cdc.gov)
  • Phase I pharmacokinetic and pharmacodynamic study of temozolomide in pediatric patients with refractory or recurrent leukemia: a Children's Oncology Group Study. (nih.gov)
  • Interestingly, chemotherapy, including hydroxyurea, has been associated with acute leukemia in JAK2 V617F-negative stem cells in some PV patients. (basicmedicalkey.com)
  • The murmur may indicate an extremely useful tool in evaluating patients with acute or insidious, and confined to the lungs ('miliary tuberculosis'), to the. (surgicalimpex.com)
  • Postchemotherapy disease-free survival was very low and many patients died during chemotherapy. (ijmpo.org)
Lineage1
Aggressive1
  • Despite the appropriate, aggressive chemotherapy, his disease showed progression that could be delayed temporarily by RANKL inhibitor denosumab monotherapy for a four month period. (biomedcentral.com)
Survival1
  • Older people whose health is too poor for intensive chemotherapy have a typical survival of five to ten months. (wikipedia.org)
Refractory1
  • Up-regulation of VEGF and its receptor in refractory leukemia cells. (nih.gov)
Cancers1
  • See Chronic Leukemias: 4 Cancers to Differentiate , a Critical Images slideshow, to help detect chronic leukemias and determine the specific type present. (medscape.com)
Infection4
  • A blood smear may also be done to monitor the side effects of chemotherapy or to help diagnose an infection, such as malaria. (medlineplus.gov)
  • Elevated WBC, leukocytosis, is seen in response to infection, stress, inflammatory disorders (referred to as reactive leukocytosis), or abnormal production as in leukemia. (medscape.com)
  • Among bone marrows studied a case of T-LL developed pancytopenia, during chemotherapy showed giant pronormoblast (Parvovirus infection). (ijmpo.org)
  • However, during the acute phase of inflammation , particularly as a result of bacterial infection , neutrophils leave the vasculature and migrate toward the site of inflammation in a process called chemotaxis . (bionity.com)
Inflammation1
  • Neutrophils react within an hour of tissue injury and are the hallmark of acute inflammation. (bionity.com)
Tumor2
  • Leukemia control cells are the AZD1080 KIAA0901 initial reported kind of tumor control cells [5]. (immune-source.com)
  • We studied 5 consecutive cases of GCT involving the distal radius operated by en-bloc resection of tumor followed by reconstruction with ipsilateral non-vascularized fibular graft with a minimum 1 year follow-up. (jbstjournal.com)
Treatment2
  • The first-line treatment of AML is usually chemotherapy, with the aim of inducing remission. (wikipedia.org)
  • The treatment is designed to wipe out the abnormally functioning leukemia cells. (oncolink.org)
Remission1
Hematopoietic1
  • T-cell depleted allogeneic hematopoietic cell transplants as a platform for adoptive therapy with leukemia selective or virus-specific T-cells. (nih.gov)
Medications1
  • In addition, chemotherapy medications can cause side effects such as mouth sores (mucositis) , diarrhea , nausea/vomiting , and hair loss (alopecia) . (oncolink.org)
Stem1
  • The patient was given salvage chemotherapy in the form of FLA-Ida with the plan to reassess at count recovery aiming for stem cell transplant. (cambridgemedicine.org)
Disorders2
Cells3
  • The underlying mechanism involves replacement of normal bone marrow with leukemia cells, which results in a drop in red blood cells, platelets, and normal white blood cells. (wikipedia.org)
  • A lumbar puncture (spinal tap) to see if there are any leukemia cells in your spinal fluid. (oncolink.org)
  • The diagnosis of Hairy Cell Leukemia and HCL-like diosrders, including HCL variant (vHCL) and Splenic Diffuse Red Pulp Lymphoma (SDRPL), is based on the examination of the peripheral blood and bone marrow smears allowing the identification of hairy cells and the flow cytometric analysis. (fortuneonline.org)
Molecular1
  • The sequence of molecular and cytogenetic changes in our patient may provide a mechanistic model for the generation of JTs in leukemia. (biomedcentral.com)
Involves1
  • Our data suggest that the formation of 1q JTs involves multiple stages and may provide a mechanistic model for the generation of JTs in leukemia. (biomedcentral.com)
Include1
  • Basophilic leukocytosis occurs when basophils are greater than 0.1 x 10 9 /L. Causes include rare allergic reactions (IgE mediated). (medscape.com)