• Therefore, we recommended adjuvant radiotherapy and chemotherapy as the alternative management. (psychiatryinvestigation.org)
  • Objective: To determine if the addition of gemcitabine to adjuvant fluorouracil chemoradiation (chemotherapy plus radiation) improves survival for patients with resected pancreatic adenocarcinoma. (northwestern.edu)
  • Conclusions: The addition of gemcitabine to adjuvant fluorouracil-based chemoradiation was associated with a survival benefit for patients with resected pancreatic cancer, although this improvement was not statistically significant. (northwestern.edu)
  • Adjuvant chemotherapy consisted of four cycles of fluorouracil-based regimens. (bepress.com)
  • Effects of adjuvant chemotherapy on specific and non-specific immune mechanisms. (curehunter.com)
  • Adjuvant chemotherapy is a well accepted concept in the treatment of breast cancer and has resulted in most clinical studies in a significant prolongation of the disease-free interval in certain subgroups of patients. (curehunter.com)
  • However, very little is known about the late effects of adjuvant chemotherapy and its influence upon the function of a series of physiologic mechanisms. (curehunter.com)
  • For suitable estrogen-receptor negative (ER)-negative patients, adjuvant chemotherapy with a proven effective regimen. (pharmacology2000.com)
  • There is continuing controversy concerning the routine use of adjuvant chemotherapy in all patients with ER-negative, node-negative cancers. (pharmacology2000.com)
  • For ER-positive patients, adjuvant chemotherapy or tamoxifen (20 milligrams daily). (pharmacology2000.com)
  • Following the treatment used to control local disease, adjuvant combination chemotherapy is given to reduce the rate of recurrence and improve survival in pre- and postmenopausal node-positive patients. (pharmacology2000.com)
  • Numerous studies have shown that combination chemotherapy is superior to single-agent treatment, and single-agent adjuvant chemotherapy should be avoided outside a clinical trial. (pharmacology2000.com)
  • Tamoxifen, either alone or combined with chemotherapy, prolongs disease-free survival when administered for 24 months as adjuvant therapy to postmenopausal women with axillary lymph node metastases. (pharmacology2000.com)
  • Mismatch repair-deficient tumors do not respond well to chemotherapy applied in the neoadjuvant, adjuvant, or metastatic settings. (cancer.gov)
  • Adjuvant polychemotherapy (e.g. with 58% to 68%) for patients under the age of 50.1 Besides an cyclophosphamide, methotrexate and 5-fluorouracil (CMF)) or improvement in clinical outcome, these figures indicate that anthracycline-containing regimes, produce substantial reduc- a large proportion of the patients will never recur after the tion in recurrence and mortality. (lu.se)
  • In order to achieve a more effec- were recommended postoperative radiation and adjuvant tive and individualised chemotherapeutic treatment of breast chemotherapy. (lu.se)
  • Cost-effectiveness of DPYD Genotyping Prior to Fluoropyrimidine-based Adjuvant Chemotherapy for Colon Cancer. (cdc.gov)
  • To assess the feasibility of QOL assessment in a cohort of Tunisian cancer patients, the EORTC QLQ-C30 questionnaire was administered to 23 women treated with adjuvant chemotherapy for early breast cancer on an outpatient basis at baseline and during the 3rd cycle of chemotherapy. (who.int)
  • Depending on each large tumours and/or histologically proven patient's education level, the questionnaire axillary lymph node involvement requiring was either self-completed or administered adjuvant cytotoxic chemotherapy. (who.int)
  • assess the feasibility of QOL evaluation in a The QLQ-C30 was assessed by the same cohort of Tunisian women with early breast physician (A.M.) at 2 points of time: just cancer receiving adjuvant chemotherapy. (who.int)
  • The chemotherapy used was the mFOLFOX6 regimen, comprising folinic acid (leucovorin), fluorouracil (5-FU), and oxaliplatin (OX). (medscape.com)
  • This chemotherapy combination contains the drugs leucovorin calcium (folinic acid), fluorouracil, irinotecan hydrochloride, and oxaliplatin. (cancer.gov)
  • a chemotherapy regimen consisting of in other areas where chikungunya fe- pdf fl uorouracil [5 FU], folinic acid, and ver has not occurred previously. (cdc.gov)
  • Purpose: This multicenter phase II study was designed to determine the efficacy and tolerability of oxaliplatin, levoforinate, and infusional 5-fluorouracil (FOLFOX4) as a second-line therapy for Japanese patients with unresectable advanced or metastatic colorectal cancer. (elsevierpure.com)
  • All other patients received a preoperative chemoradiotherapy (CRT) with 50.4 Gy and concomitant 5-fluorouracil (5-FU) or 5-FU+oxaliplatin followed by postoperative chemotherapy with 5-FU or 5-FU+oxaliplatin. (jcancer.org)
  • Advanced gastric cancer (AGC) rarely presents with disseminated intravascular coagulation (DIC) at the time of diagnosis before treatment with no current standard chemotherapy (CTx) regimen. (nih.gov)
  • It is indicated as part of a combination chemotherapy regimen for persistent, recurrent, or metastatic carcinoma of the cervix. (medscape.com)
  • Cases of neutrophilic eccrine hidradenitis resolving after withdrawal of chemotherapy and recurring upon reinstitution of the same regimen favor the former. (medscape.com)
  • Twenty six (65%) patients had the opportunity to receive a classic chemotherapy regimen following metronomic regimen interruption. (scirp.org)
  • I do agree with the author's assertions that (1) patients similar to those treated in the randomized studies should be offered combination chemotherapy, (2) a best regimen has not been identified, and (3) not all physicians agree that the magnitude of survival benefit makes combination chemotherapy a standard treatment for patients with disseminated non-small-cell lung cancer. (cancernetwork.com)
  • Cost-Effectiveness Analysis of a New Second-Line Treatment Regimen for Advanced Intrahepatic Cholangiocarcinoma: Biomarker-Driven Targeted Therapy of Pemigatinib Versus 5-FU Chemotherapy. (cdc.gov)
  • Although can- number of positive axillary lymph nodes cer incidence is increasing in the developing and chemotherapy regimen. (who.int)
  • Outpatient weekly high-dose continuous-infusion 5-fluorouracil plus oral leucovorin in advanced colorectal cancer. (bvsalud.org)
  • We investigated the effectiveness of sequential CTx with methotrexate and 5-fluorouracil (MF) in chemotherapy-naive AGC patients with DIC. (nih.gov)
  • p53, mdm-2, p21, and mib-1 expression were assessed by immunohistochemical methods in primary tumors derived from 134 patients who took part in a randomized multicenter trial comparing docetaxel to sequential methotrexate and 5-fluorouracil (MF) in advanced breast cancer. (lu.se)
  • Chemotherapy regimens for esophageal cancer have been found to work better when drugs are combined. (epnet.com)
  • Although highly preliminary, the findings suggest that different tumor biological factors may predict response to different chemotherapy regimens with distinct mechanisms of action. (lu.se)
  • However, there are no data in literature reporting the patient's tolerance and response to subsequent lines of chemotherapy after receiving metronomic regimens. (scirp.org)
  • p53, mdm-2, p21, and mib-1 expression were not significantly associated with response to chemotherapy, time to progression, or overall survival in the whole patient population or in the docetaxel group. (lu.se)
  • The impact of therapeutic drug management (TDM) on reducing toxicity and improving efficacy in colorectal cancer (CRC) patients receiving fluorouracil-based chemotherapy is still unclear. (medscimonit.com)
  • TDM in colorectal cancer can reduce toxicity, improve efficacy and clinical outcome, and can be routinely used in 5-FU-based chemotherapy. (medscimonit.com)
  • Methods: Metastatic gastric cancer patients with stable disease or a better response after the completion of first-line chemotherapy were randomized to oral UFT (360mg/m2 × 2 weeks) every 3 weeks until disease progression/intolerable toxicity or to observation (OBS). (oncotarget.com)
  • Biochemical basis for familial pyrimidinemia and severe 5-fluorouracil-induced toxicity. (thieme-connect.de)
  • 10 Johnson M R, Hageboutros A, Wang K, High L, Smith J B, Diasio R B. Life-threatening toxicity in a dihydropyrimidine dehydrogenase- deficient patient after treatment with topical 5-fluorouracil. (thieme-connect.de)
  • The following data were collected: age, hormone and epidermal growth factor receptor 2 (HER-2) status, number of lines of chemotherapy prior to and after low-dose metronomic treatment, duration of metronomic treatment, toxicity reason for treatment discontinuation. (scirp.org)
  • Consider induction chemotherapy with TPF schedule only in those patients with N bulky and fast tumor growth, individualizing benefit and toxicity. (medscape.com)
  • Concomitant radiotherapy and cetuximab have shown a benefit in locoregional control and overall survival compared to radiotherapy alone with a better toxicity profile compared to chemotherapy. (medscape.com)
  • For fluorouracil: Patients with dihydropyrimidine dehydrogenase (DPD) deficiency are unable to metabolize fluorouracil normally and may have severe unexpected toxicity to fluorouracil. (medscape.com)
  • Chemotherapy should be administered in conjunction with radiation therapy to most patients with stage IB (high-risk) to stage IVA cervical cancer. (medscape.com)
  • Fifty-nine patients with esophageal carcinoma underwent an esophagectomy after DCF or bDCF therapy as primary chemotherapy. (biomedcentral.com)
  • Background: Maintenance therapy proves to be effective in advanced lung and breast cancer after initial chemotherapy. (oncotarget.com)
  • Chemotherapy and targeted therapy are used to treat esophageal cancer. (epnet.com)
  • Chemotherapy for esophageal cancer is most often used in combination with radiation therapy (called chemoradiation). (epnet.com)
  • Unlike chemotherapy, targeted therapy drugs attack cancer cells without harming healthy cells. (epnet.com)
  • Radiation therapy plays an important role in the management of these diverse malignancies, including its use prior to surgery, as definitive treatment with chemotherapy and for. (rochester.edu)
  • First-line therapy for HER2− mG/GEJ adenocarcinoma generally consists of chemotherapy and immunotherapy, but among patients with advanced disease, the prognosis continues to be poor, and therapeutic options are limited. (medscape.com)
  • A 2018 article concludes that animal and in vitro studies suggest the potential benefits of ozone therapy for cancer treatment, alongside conventional treatments such as radiotherapy or chemotherapy. (medicalnewstoday.com)
  • Although advances in chemotherapy and the development of specific antibody therapies, surgery as well as radiation therapy have been made, long-term outcome and disease-free survival rates still have not improved. (jcancer.org)
  • 3 , 4 The current therapy for ovarian cancer is debulking surgery followed by chemotherapy using carboplatin and paclitaxel (PTX). (nature.com)
  • 5 Although ovarian cancer in advanced stages initially appears to be chemotherapy sensitive as response rates to platinum-based therapy exceed 80%, long-term survival remains poor as a result of recurrence and emergence of drug resistance. (nature.com)
  • Testing for Dihydropyrimidine Dehydrogenase Deficiency to Individualize 5-Fluorouracil Therapy. (cdc.gov)
  • Oral mucositis (OM) is a debilitating acute inflammation of patients undergoing cancer therapy including high doses of chemotherapy or head and neck radiotherapy. (bvsalud.org)
  • 5-FU TDM results, including recommended dose adjustments based on exposure levels (AUC), will be provided to the treating clinician based on the International Association of Therapeutic Drug Monitoring and Clinical Toxicology Recommendations for 5-Fluorouracil Therapy. (who.int)
  • 5-Fluorouracil (5-FU) is widely applied in the treatment of various cancers, including colorectal cancer (CRC) [1,2]. (medscimonit.com)
  • The Spanish experience with high-dose infusional 5-fluorouracil (5-FU) in colorectal cancer. (bvsalud.org)
  • Association of emergence of new mutations in circulating tumuor DNA during chemotherapy with clinical outcome in metastatic colorectal cancer. (cdc.gov)
  • PhaRmacogEnomiC medIcines optimiSatIon for peOple with caNcer - a multicentre teletrial enabled Interrupted Time Series trial (PRECISION-ITS): A nested cohort substudy evaluating the safety & efficacy of 5-Fluorouracil Therapeutic Drug Monitoring in patients with metastatic/unresectable colorectal cancer. (who.int)
  • Maintenance treatment of Uracil and Tegafur (UFT) in responders following first-line fluorouracil-based chemotherapy in metastatic gastric cancer: a. (oncotarget.com)
  • The purpose of this phase II study was to evaluate the efficacy and safety of Uracil and Tegafur (UFT) maintenance in metastatic gastric cancer patients following the first-line fluorouracil-based chemotherapy. (oncotarget.com)
  • Fluorouracil is a pyrimidine antimetabolite. (medscape.com)
  • Fluorouracil is in the antimetabolite and pyrimidine analog families of medications. (wikipedia.org)
  • All You Need to Know About DPYD Genetic Testing for Patients Treated With Fluorouracil and Capecitabine: A Practitioner-Friendly Guide. (cdc.gov)
  • In breast cancer patients, it is unclear whether measuring p53, mdm-2, or p21 expression provides information on how patients will respond to chemotherapy. (lu.se)
  • This research evaluated executive functions in women with breast cancer undergoing chemotherapy. (bvsalud.org)
  • It is concluded that there were impairments in executive functions related to working memory, focused attention, inhibitory control and general impulsivity in the group of women with breast cancer who received chemotherapy. (bvsalud.org)
  • Trastuzumab, when used with chemotherapy, may help stop tumor growth in cancers with an excess amount of HER2. (epnet.com)
  • We have recently reported that certain chemotherapeutics, including 5-fluorouracil (5-FU), may in fact stimulate angiogenesis in the tumor-free rat mesenteric window assay. (unboundmedicine.com)
  • High tumor proliferation has previously been associated with response to chemotherapy. (lu.se)
  • The results of our phenotype analysis also indicate that it is more likely that a panel of tumor biological factors instead of only one single factor may be needed for better prediction of chemotherapy response. (lu.se)
  • The patient demographics, tumor characteristics, context of STZ chemotherapy, and patient outcome were collected and assessed. (cancerindex.org)
  • The ability of a tumor to resist chemotherapy treatment following an initial response. (ucsfhealth.org)
  • Chemoradiation with a continuous infusion of fluorouracil (250 mg/m 2 per day) was the same for all patients (50.4 Gy). (northwestern.edu)
  • 7 Harris B E, Song R, Soong S J, Diasio R B. Relationship between dihydropyrimidine dehydrogenase activity and plasma 5- fluorouracil levels with evidence for circadian variation of enzyme activity and plasma drug levels in cancer patients receiving 5- fluorouracil by protracted continuous infusion. (thieme-connect.de)
  • A medical oncologist will determine how many cycles of chemotherapy are needed and what combination of drugs will work best. (epnet.com)
  • Update on chikungu- chemotherapy consisting of 6 cycles nya: 13th October 2006. (cdc.gov)
  • He had undergone surgery and had 3 cycles of Cisplastin, 5-Fluorouracil and Adriamycin on account of carcinoma of the head of pancreas. (bvsalud.org)
  • TDM will commence from the patient's first chemotherapy cycle and will be repeated at consecutive chemotherapy cycles of 5-FU until the target AUC is reached (20-30mg - h/L). Dosing recommendations will be based on single timepoint blood sample collection 18-40hours after commencement of infusional 5-FU. (who.int)
  • Implementing Pharmacogenetic Testing in Gastrointestinal Cancers (IMPACT-GI): Study Protocol for a Pragmatic Implementation Trial for Establishing DPYD and UGT1A1 Screening to Guide Chemotherapy Dosing. (cdc.gov)
  • Cancers such as doxorubicin are commonly used in cancer leukaemia, colorectal, breast, lung, and so on are chemotherapy. (who.int)
  • Fluorouracil (5-FU, 5-fluorouracil), sold under the brand name Adrucil among others, is a cytotoxic chemotherapy medication used to treat cancer. (wikipedia.org)
  • Induction chemotherapy followed by locoregional treatment. (medscape.com)
  • The case-group underwent oral hygiene control associated with the use of chamomile tea before starting the first cycle of chemotherapy, while the control group, there were no previous guidelines and prescriptions. (bvsalud.org)
  • When used alone, chemotherapy is not an effective treatment for esophageal cancer or long-term survival. (epnet.com)
  • Chemotherapy for esophageal cancer may given before or after surgery . (epnet.com)
  • SAN FRANCISCO ― An experimental monoclonal antibody combined with chemotherapy could offer a new standard of care for patients with claudin-18.2+ (CLDN18.2+) / HER2− advanced gastric or gastroesophageal junction (mG/GEJ) adenocarcinoma, say researchers in reporting a phase 3 trial. (medscape.com)
  • Chemotherapy with streptozocin (STZ) in combination with 5-FU or doxorubicin (Dox) represents a standard of care for patients with metastatic pancreatic neuroendocrine neoplasms (pNEN). (cancerindex.org)
  • Used in the frontline setting, zolbetuximab (under development by Ganymed Pharmaceuticals AG) combined with chemotherapy led to significantly longer progression-free survival and overall survival compared to what was seen with chemotherapy alone. (medscape.com)
  • The author then comments on four meta-analyses performed on eight small studies, which showed that the survival of patients with disseminated non-small-cell lung cancer treated with supportive care is shorter than the survival of patients treated with combination chemotherapy. (cancernetwork.com)
  • Standard chemotherapy works by killing cancer cells and some normal cells. (medlineplus.gov)
  • They may work when standard chemotherapy drugs have not worked. (epnet.com)
  • Neutrophilic eccrine hidradenitis (NEH) was initially described in acute myelogenous leukemia (AML) patients undergoing chemotherapy. (medscape.com)
  • The mechanism(s) of neutrophilic eccrine hidradenitis (NEH) is unknown, although neutrophilic eccrine hidradenitis pathologic changes observed with intradermal bleomycin injections support a direct toxic effect of chemotherapy. (medscape.com)
  • More than 70% of oncology patients who develop neutrophilic eccrine hidradenitis do so after their first course of chemotherapy. (medscape.com)
  • A direct toxic effect of chemotherapy and a paraneoplastic mechanism have both been proposed to explain neutrophilic eccrine hidradenitis in the context of malignancy. (medscape.com)
  • Patients who have received prior chemotherapy should be given a lower dose initially. (medscape.com)
  • Animal studies have demonstrated that frequent administration of chemotherapeutics may have marked antiangiogenic effects and improved antitumor effects, with less severe toxic side-effects than intermittent maximum tolerated dose chemotherapy. (unboundmedicine.com)
  • Currently, research focused on low-dose antiangiogenic chemotherapy is increasing. (unboundmedicine.com)
  • Albertsson P, Lennernäs B, Norrby K. Low-dose continuous 5-fluorouracil infusion stimulates VEGF-A-mediated angiogenesis. (unboundmedicine.com)
  • TY - JOUR T1 - Low-dose continuous 5-fluorouracil infusion stimulates VEGF-A-mediated angiogenesis. (unboundmedicine.com)
  • Purpose: Low-dose metronomic chemotherapy is an emergent treatment schedule in which low doses of cytotoxic agents are given orally continuously, with no or short drug-free intervals. (scirp.org)
  • Duration of low-dose metronomic chemotherapy was also correlated with the variables analyzed and treatment outcomes. (scirp.org)
  • For fluorouracil: Liver function should be assessed prior to each cycle for potential dose evaluation. (medscape.com)
  • Cancer patients developing severe side effects upon chemotherapy with 5-fluorouracil (5-FU) are assumed to display reduced activity of the enzyme dihydropyrimidine dehydrogenase (DPD). (thieme-connect.de)
  • Treatment options for gallbladder cancer include surgery, chemotherapy, and radiation, alone or in combination. (rxwiki.com)
  • During the same period, she received intravenous chemotherapy, in the form of 790 mg (500 mg/m 2 ) fluorouracil (5-FU) and 32 mg (20 mg/m 2 ) calcium folinate, for 5 consecutive days at 3-week intervals. (psychiatryinvestigation.org)
  • Research done here has helped the standard care for vulvar cancer evolve into less-radical surgery combined with other therapies, including chemotherapy and radiation. (mdanderson.org)
  • There is a need for better therapies, as chemotherapy is still the primary treatment," said Shitera. (medscape.com)
  • One such test that has been shown to successfully monitor 5-FU plasma levels and which "may contribute to improved efficacy and safety of commonly used 5-FU-based chemotherapies" is the My5-FU test. (wikipedia.org)
  • Fluorouracil's efficacy is decreased when used alongside allopurinol, which can be used to decrease fluorouracil induced stomatitis through use of allopurinol mouthwash. (wikipedia.org)
  • To evaluate the benefit of cetuximab (Cx) addition to platinum-based and 5-fluorouracil chemotherapy (PFU) in unselected recurrent and/or metastatic head and neck cancer patients (R/MHNC) according to KRAS-LCS6 variant status. (nih.gov)
  • Indicated for treatment of recurrent or metastatic cervical cancer with disease progression on or after chemotherapy whose tumors express PD-L1 (CPS 1 or greater) as determined by an FDA-approved test. (medscape.com)
  • The patient presented manic symptoms after 4th cycle of 5-FU chemotherapy after surgery of rectal cancer. (psychiatryinvestigation.org)
  • Patients generally have chemotherapy after surgery for cancer, regardless of its stage. (psychiatryinvestigation.org)
  • We report the case of a woman who developed an acute manic episode after receiving 5-FU chemotherapy during treatment for rectal cancer. (psychiatryinvestigation.org)
  • Chemotherapy is the use of medicine to treat cancer. (medlineplus.gov)
  • Chemotherapy kills cancer cells. (medlineplus.gov)
  • Below are the seven main types of chemotherapy, the types of cancer they treat, and examples. (medlineplus.gov)
  • Chemotherapy uses drugs to kill cancer cells. (epnet.com)
  • Chemotherapy is a general term for medications used to destroy or stop the growth of cancer cells. (curesearch.org)
  • This Children's Cancer and Chemotherapy video explains how cancer treatments are developed and administered. (curesearch.org)
  • Chemotherapy works by interfering with the ability of cancer cells to divide and duplicate themselves. (curesearch.org)
  • Chemotherapy can be given through the bloodstream to reach cancer cells all over the body, or it can be delivered directly to specific cancer sites. (curesearch.org)
  • Chemotherapy is given in different ways depending on the cancer type and the medicines used. (curesearch.org)
  • The length of treatment depends upon the cancer type and how responsive it is to the chemotherapy. (curesearch.org)
  • This trial is looking at chemotherapy before surgery for bowel cancer to improve treatment. (cancerresearchuk.org)
  • You might then have chemotherapy to kill off any remaining cancer cells. (cancerresearchuk.org)
  • We know from recent research that giving some chemotherapy first worked for younger, fitter people with bowel cancer. (cancerresearchuk.org)
  • This is because sometimes chemotherapy doesn't work well for cancer on the right side of the bowel. (cancerresearchuk.org)
  • New recommendation on pharmacogenetic screening prior to 5-fluorouracil based cancer treatment - Swedish experience indicates less adverse effects and healthcare cost savings]. (cdc.gov)
  • Mismatch Repair Deficient Rectal Cancer and Resistance to Neoadjuvant Chemotherapy. (cdc.gov)
  • Cancer is a notable deadly disease involving such as fluorouracil, methotrexate and several other diseases. (who.int)
  • Afin d'estimer la faisabilité d'une évaluation de la qualité de vie dans une cohorte de patients cancéreux tunisiens, nous avons présenté le questionnaire QLQ-C30 de l'EORTC à 23 femmes traitées par chimiothérapie adjuvante en ambulatoire pour un cancer du sein à un stade précoce, au début du traitement et pendant le troisième cycle de chimiothérapie. (who.int)
  • Il est nécessaire d'améliorer encore l'infrastructure de soins et la sensibilisation du public en matière de cancer si l'on veut réaliser des études fiables sur la qualité de vie des cancéreux. (who.int)
  • This report describes a cancer patient, who had undergone chemotherapy and developed CNF of odontogenic origin to highlight the need for oral examination before commencement of chemotherapy.Case description: A 68 years old retired gardener who developed CNF from infected right permanent mandibular first and second molars. (bvsalud.org)
  • Cognitive changes may occur during chemotherapy to treat cancer and, therefore, it is necessary to identify them since they represent neurological complications with a high rate of improvement when treated. (bvsalud.org)
  • Streptozocin chemotherapy for advanced/metastatic well-differentiated neuroendocrine tumors: an analysis of a multi-center survey in Japan. (cancerindex.org)
  • Methods: A total of 53 patients with progressive disease after first-line chemotherapy were enrolled in the study. (elsevierpure.com)
  • 1% frequency): Local pain Itchiness Burning Stinging Crusting Weeping Dermatitis Photosensitivity Uncommon (0.1-1% frequency): Hyper- or hypopigmentation Scarring The United States package insert warns that acute cerebellar syndrome has been observed following injection of fluorouracil and may persist after cessation of treatment. (wikipedia.org)
  • A diagnosis of toxic erythema of chemotherapy has been proposed for this group of disorders, to emphasize the overlapping clinical and histological features with similar eruptions. (medscape.com)
  • 9 Heggie G D, Sommadossi J P, Cross D S, Huster W J, Diasio R B. Clinical pharmacokinetics of 5-fluorouracil and its metabolites in plasma, urine, and bile. (thieme-connect.de)
  • A series of studies have revealed that exosomes-mediated intercellular transfer of proteins, nucleic acids, and metabolites plays a crucial role in the initiation and progression of HCC, hypoxia and angiogenesis, chemotherapy sensitivity, and cell death mode and regulates the immune microenvironment. (hindawi.com)