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  • agonist
  • Bitolterol mesylate (Tornalate) is a short-acting β2 adrenergic receptor agonist used for the relief of bronchospasm in conditions such as asthma and COPD. (wikipedia.org)
  • Identification of in vitro metabolites of JWH-015, an aminoalkylindole agonist for the peripheral cannabinoid receptor (CB2) by HPLC-MS/MS". Analytical and Bioanalytical Chemistry. (wikipedia.org)
  • chloride
  • Mesylates are generally prepared by treating an alcohol and methanesulfonyl chloride in the presence of a base, such as triethylamine. (wikipedia.org)
  • Though the latter step is still commonly used for functionalization of stannatrane chloride to simple alkyl derivatives via transmetalation, Biscoe and coworkers have developed a lithiation method that provides access to a variety of enantioenriched alkyl substituents from optically active mesylates (2). (wikipedia.org)
  • After treatment of stannatrane chloride with lithium napthalide, a lithium carbastannatrane was quenched with the corresponding enantiopure mesylate to yield the desired enantioenriched alkyl carbastannatrane in moderate yield with high enantiomeric excess. (wikipedia.org)
  • drug
  • Fluoroquinolones "Center for Drug Evaluation and Research - Application Number: 020759/020760 - Chemistry Review(s)" (PDF). (wikipedia.org)
  • salt
  • Alatrofloxacin (Trovan IV) is a fluoroquinolone antibiotic developed by Pfizer, delivered as a mesylate salt. (wikipedia.org)
  • Volume
  • Nosylate Sulfate Sulfoxide Sulfonyl Ueber eine neue Bildungsweise und die Constitution der Sulfosäuren Annalen der Chemie und Pharmacie Volume 148, Issue 1, Pages 90 - 96 (p 90-96) 1868 doi:10.1002/jlac.18681480108 R. J. Cremlyn "An Introduction to Organosulfur Chemistry" John Wiley and Sons: Chichester (1996). (wikipedia.org)
  • alternative
  • Related methodology enable selective acyl substitution using enantioenriched stannatranes as an alternative to classical enolate chemistry. (wikipedia.org)
  • science
  • What about science and chemistry in particular? (slideshare.net)
  • The goals of the outreach program, as described on the NanoKids website, are: "To significantly increase students' comprehension of chemistry, physics, biology, and materials science at the molecular level. (wikipedia.org)
  • imatinib
  • When modifying the International Nonproprietary Name of a pharmaceutical substance containing the group or anion, the correct spelling is mesilate (as in imatinib mesilate, the mesylate salt of imatinib). (wikipedia.org)
  • For example, DHFR amplification occurs in response to methotrexate, TYMS (involved in DNA synthesis) amplification occurs in response to 5-fluorouracil, and BCR-ABL amplification occurs in response to imatinib mesylate. (wikipedia.org)
  • Agonist
  • Bitolterol mesylate (Tornalate) is a short-acting β2 adrenergic receptor agonist used for the relief of bronchospasm in conditions such as asthma and COPD. (wikipedia.org)
  • Identification of in vitro metabolites of JWH-015, an aminoalkylindole agonist for the peripheral cannabinoid receptor (CB2) by HPLC-MS/MS". Analytical and Bioanalytical Chemistry. (wikipedia.org)
  • Reactions
  • The new coupling reactions proposed in this application do not require specialized techniques or the exclusion of air, empowering those in the health sciences, even those with limited chemistry experience, to synthesize needed molecules themselves. (grantome.com)
  • Mesylate is considered a leaving group in nucleophilic substitution reactions. (wikipedia.org)
  • alcohol
  • Below some relative rates of reaction (NaI in acetone at 60 °C): In modern usage the definition of the reaction has been expanded to include the conversion of alcohols to alkyl halides by first converting the alcohol to a sulfonate ester (tosylates or mesylates are usually used), and then performing the substitution. (wikipedia.org)
  • Mesylates are generally prepared by treating an alcohol and methanesulfonyl chloride in the presence of a base, such as triethylamine. (wikipedia.org)
  • salt
  • The form brought to market by Teva and its partners is the mesylate salt, and was designated chemically as: 1H-Inden-1-amine-2,3-dihydro-N-2-propynyl-(1R)-methanesulfonate. (wikipedia.org)
  • Alatrofloxacin (Trovan IV) is a fluoroquinolone antibiotic developed by Pfizer, delivered as a mesylate salt. (wikipedia.org)
  • Synthetic
  • J Neurochem 76:110 Szapiro G, and that atropine sulfate 3 mgday or synthetic anticholinergic agents (such as benzatropine mesylate 4 mgday) ameliorate withdra- wal symptoms within a few hours. (forexturboprofits.com)
  • In addition to the naturally occurring ergonovine (used as an oxytocic) and ergotamine (a vasoconstrictor used to control migraine), synthetic derivatives of importance are the oxytocic methergine, the anti-migraine drugs dihydroergotamine and methysergide, hydergine (a mixture of dihydroergotoxine mesylates, INN: ergoline mesylates), and bromocriptine, used for numerous purposes including treatment of Parkinson's disease. (wikipedia.org)