Channels membrane glycoproteins. Medical search. Frequent questions

Both have plasma membranes and ribosomes (structures that synthesize proteins[clarification needed] and float free in cytoplasm). (wikipedia.org)
Lipids and proteins are synthesized[clarification needed] in the ER, and carbohydrates are added to make glycoproteins. (wikipedia.org)
Proteins with receptor sites are located on the plasma membrane, binding to specific solutes. (wikipedia.org)
Receptor proteins are recycled back to the plasma membrane by the same vesicle. (wikipedia.org)
Accumulation of APP across mitochondrial import channels, which varied with the severity of AD, inhibited the entry of nuclear-encoded cytochrome c oxidase subunits IV and Vb proteins, which was associated with decreased cytochrome c oxidase activity and increased levels of H 2 O 2 . (jneurosci.org)
The Rh blood group antigens (MIM 111700) are associated with human erythrocyte membrane proteins of approximately 30 kD, the so-called Rh30 polypeptides. (novusbio.com)
Heterogeneously glycosylated membrane proteins of 50 and 45 kD, the Rh50 glycoproteins, are coprecipitated with the Rh30 polypeptides on immunoprecipitation with anti-Rh-specific mono- and polyclonal antibodies. (novusbio.com)
Proteins act as Cell Identification Markers Lipids and proteins within the membrane may have a carbohydrate chain attached These glycolipids and glycoproteins often function as cell ID markers, allowing cells to identify other cells This is particularly important in the immune system where cells patrolling the body's tissues identify and destroy foreign invaders such as bacteria or viruses. (slideshare.net)
Channel Proteins In some cases the channel proteins simply act as a passive pore. (slideshare.net)
Carrier Proteins They do not extend through the membrane They bond and drag molecules through the lipid bilayer and release them on the opposite side. (slideshare.net)
The strong expression of ATP-gated P2X3 receptors by a subpopulation of sensory neurons indicates the important role of these membrane proteins in nociceptive signaling in health and disease, especially when the latter is accompanied by chronic pain syndromes. (gozmusic.org)
The conclusions point toward a possible role for ion channel activities, membrane potential changes and alterations of the lateral organization of proteins in transmembrane signaling and cytotoxic interactions. (unideb.hu)
A role for MHC glycoproteins in concentrating membrane proteins and organizing protein patterns is suggested, and the possibility that the membrane potential may modulate protein conformation and, thereby, affect protein-protein interactions is pointed out. (unideb.hu)
These functionally inappropriate proteins are somehow detected in the ER lumen and then transferred to the retrotranslocational channel embedded within the ER membrane, termed the retrotranslocon, followed by ubiquitin-dependent degradation by the proteasome in the cytoplasm. (elifesciences.org)
Proteins span the cell membrane and allow large or charged molecules across the cell membrane. (knowt.com)
Channel proteins: allow dissolved molecules to diffuse through the membrane. (everythingask.com)
Recognition proteins: These proteins, called glycoproteins (glyco = sugar) have complex carbohydrates attached to them. (everythingask.com)
Pre-validated Shotgun Mutagenesis target libraries are also available for several human membrane and viral envelope proteins, including Ebola virus glycoprotein. (integralmolecular.com)
In fact, there is a considerable difference between the array of phospholipids and proteins between the two leaflets that form a membrane. (iprep.kz)
On the interior of the membrane, some proteins serve to anchor the membrane to fibers of the cytoskeleton. (iprep.kz)
There are peripheral proteins on the exterior of the membrane that bind elements of the extracellular matrix. (iprep.kz)
Carbohydrates , attached to lipids or proteins, are also found on the exterior surface of the plasma membrane. (iprep.kz)
The enveloped influenza A virions have three membrane proteins (HA, NA, M2), a matrix protein (M1) just below the lipid bilayer, a ribonucleoprotein core (consisting of 8 viral RNA segments and three proteins: PA, PB1, PB2), and the NEP/NS2 protein. (virology.ws)
Moreover, lateral motility of membrane proteins was analyzed by calculating diffusion coefficients and kymograph analysis, which represented an alternative method for examining protein motility. (biomedcentral.com)

Ebolavirus, a deadly hemorrhagic fever virus, was thought to enter cells through endolysosomes harboring its glycoprotein receptor, Niemann-Pick C1. (ox.ac.uk)
2015). Geometric rules of channel gating inferred from computational models of the P2X receptor transmembrane domain. (gozmusic.org)
1997). Receptor and ion channel nomenclature supplement. (gozmusic.org)
2011). The Intracellular Amino Terminus Plays a Dominant Role in Desensitization of ATP-gated P2X Receptor Ion Channels. (gozmusic.org)
2011). Cysteine scanning mutagenesis (residues Glu52-Gly96) of the human P2X1 receptor for ATP: mapping agonist binding and channel gating. (gozmusic.org)
The analysis surveys the lateral organization of major histocompatibility complex glycoproteins, intercellular adhesion molecule-1, interleukin-2 and -15 receptors, Kv1.3 K+ ion channels and the T-cell receptor as well as their behavior under different conditions. (unideb.hu)
A well-defined role for the presence of ion channels in the immune synapse is offered, which could explain the significance of ion channel accumulation in the immune synapse together with the T-cell receptor. (unideb.hu)
The flow-dependent adhesion of platelets to those and other extracellular matrix components is stabilized by a panel of integrins, including integrin α 2 β 1 , α IIb β 3 , and α 6 β 1 (adhesive platelet population), while the initial activation of platelets is achieved by signaling via the collagen/laminin receptor, glycoprotein VI (GPVI). (frontiersin.org)
Lägga till sterila PEG 8000 i fosfatbuffrad saltlösning (PBS) insamlade medellång till en Kinetics of the bile acid transporter and hepatitis B virus receptor Na+/taurocholate cotransporting polypeptide (NTCP) in hepatocytes. (web.app)
СCR 5 receptor within the membrane. (iprep.kz)
Platelet receptors for ADP include the P2Y12 receptor, which sends signals to suppress adenylate cyclase, decreases cyclic adenosine monophosphate (cAMP) levels, and promotes activation of the glycoprotein IIb/IIIa receptor (assembled on the activated platelet surface membrane from glycoproteins IIb and IIIa). (msdmanuals.com)

These findings show that the three PY motifs in the C-termini of ENaC are involved in the regulation of channel activity, probably via protein-protein interactions. (nih.gov)
Here we report that nonglycosylated full-length and C-terminal truncated amyloid precursor protein (APP) accumulates exclusively in the protein import channels of mitochondria of human AD brains but not in age-matched controls. (jneurosci.org)
The major constituent of a senile plaque is β-amyloid (Αβ), which is a 40-43 amino acid peptide produced by the action of secretory pathway-associated proteases, namely β and γ secretases, at the C terminus of a type I membrane-spanning glycoprotein termed amyloid precursor protein (APP). (jneurosci.org)
The protocols describe the essential steps for obtaining diffraction quality crystals of a membrane protein starting from reconstitution of the protein in a lipidic cubic phase (LCP), finding initial conditions with LCP-FRAP pre-crystallization assays, setting up LCP crystallization trials and harvesting crystals. (jove.com)
The M2 is a transmembrane protein that forms an ion channel required for the uncoating process that precedes viral gene expression. (cdc.gov)
Composition of Cell Membrane  Cell Membranes are NOT all identical, but have FOUR common parts:  Lipid Bilayer  Transmembrane Protein  Network of supporting fibers  Glycoproteins  On outside of cell  Cell Surface has a carbohydrate coat to prevent sticking. (slideshare.net)
Previously, we described conserved protein clusters includingMHCI and II glycoproteins, ICAM-1 adhesion molecules, and interleukin- 2 and -15 receptors in lipid rafts of several human cell types. (unideb.hu)
The formation of protein patterns in lymphocyte plasma membranes is analyzed in the light of past and, also, very recent experiments. (unideb.hu)
In our outlook new factors that potentially affect membrane protein cluster formation and interactions are discussed. (unideb.hu)
Productive folding of the protein moiety is facilitated during this period by the calnexin/calreticulin cycle in mammalian cells, which relies on G1M9-specific lectin-type chaperones (calnexin and calreticulin) associated with the oxidoreductase ERp57, and UDP-glucose:glycoprotein glucosyltransferases 1 and 2, which are capable of re-adding glucose to M9 if the protein moiety is not yet folded. (elifesciences.org)
To support the creation of Ebola virus vaccines and treatments, Integral Molecular, a leader in membrane protein antibody discovery, has identified the key molecular interactions that mediate the effectiveness of the anti-Ebola ZMapp™ therapeutic cocktail, which is in clinical trials after being used to treat select patients during the 2014 Ebola virus outbreak. (integralmolecular.com)
Integral Molecular is a research-driven biotechnology company creating innovative technologies and a pipeline of therapeutic antibodies against under-exploited membrane protein targets, including GPCRs, ion channels, transporters, and viral envelopes. (integralmolecular.com)
Like the M2 protein of influenza A virus, the BM2 protein is a proton channel that is essential for the uncoating process . (virology.ws)
The NB protein is believed to be an ion channel, but it is not required for viral replication in cell culture. (virology.ws)
The M1 protein lies just below the membrane, as in influenza A and B virions. (virology.ws)
A minor viral envelope protein is CM2, which functions as an ion channel. (virology.ws)
The present study presented experimental evidence on illustrating the use of VAEM in tracking and dissecting protein dynamics, dissecting endosomal dynamics, cell structure assembly along with membrane microdomain and protein motility in intact plant cells. (biomedcentral.com)
Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient. (nih.gov)

Glycoproteins undergo further synthesis[clarification needed] in the Golgi apparatus, becoming glycolipids. (wikipedia.org)
Both glycoproteins and glycolipids are transported into vesicles to the plasma membrane. (wikipedia.org)
Development of Lewis antigens o Depending on the genes inherited, Lea and Leb glycoproteins will be present in the saliva of ewborns, but Lewis glycolipids are not detectable in the plasma until about 10 days after birth. (keepnotes.com)

Ions travel across cell membranes through channels, pumps or transporters. (wikipedia.org)
Sodium-hydrogen exchangers (Na + /H + exchangers, NHE) are ATP-independent membrane glycoprotein transporters that are involved in the regulation of intracellular pH, cell volume and the cellular response to hormones and mitogens. (tocris.com)
The transporters mediate the simultaneous efflux of a hydrogen ion and the influx of a sodium ion across the plasma membrane, the driving force being the inwardly directed electrochemical Na + gradient. (tocris.com)

The HA glycoprotein forms spikes at the surface of virions, mediating attachment to host cell sialoside receptors and subsequent entry by membrane fusion. (cdc.gov)
Here, we show that following stimulation of cysteinyl leukotriene type I receptors in rat basophilic leukemia (RBL)-1 cells, large amplitude Ca(2+) oscillations, CRAC channel activity, and downstream Ca(2+)-dependent nuclear factor of activated T cells (NFAT)-driven gene expression are all exclusively maintained by the endoplasmic reticulum Ca(2+) sensor stromal interaction molecule (STIM) 1. (ox.ac.uk)
However, evidence is now accumulating for rapid corticosteroid actions 25 , 26 , and the existence of membrane-bound steroid receptors that may mediate these rapid actions 27 , 28 . (ersjournals.com)
Here, we review current knowledge how proteases act on platelet receptors and the platelet membrane surface. (frontiersin.org)
VWF binds to receptors on the platelet surface membrane (glycoprotein Ib/IX). (msdmanuals.com)

Furthermore, in AD brains, mitochondrially associated APP formed stable ∼480 kDa complexes with the translocase of the outer mitochondrial membrane 40 (TOM40) import channel and a super complex of ∼620 kDa with both mitochondrial TOM40 and the translocase of the inner mitochondrial membrane 23 (TIM23) import channel TIM23 in an "N in mitochondria -C out cytoplasm " orientation. (jneurosci.org)
Phosphatidylserine-exposing platelets, usually located around a thrombus, provide a negatively charged membrane surface, which supports coagulation factor binding and the formation of tenase and prothrombinase complexes ( 6 , 7 ). (frontiersin.org)
Voltage-gated sodium channels are transmembrane glycoprotein complexes composed of a large alpha subunit with four repeat domains, each of which is composed of six membrane-spanning segments, and one or more regulatory beta subunits. (nih.gov)
Fibrinogen binds to the glycoprotein IIb/IIIa complexes of adjacent platelets, connecting them into aggregates. (msdmanuals.com)

A voltage-gated sodium channel subtype that mediates the sodium ion permeability of excitable membranes. (rush.edu)
Mediates the voltage-dependent sodium ion permeability of excitable membranes. (nih.gov)
Abnormalities of red cell membrane cation permeability are seen in several hereditary disorders. (medscape.com)
Any disturbances in membrane cation permeability alter cellular hydration and can cause numerous effects, including hemolysis. (medscape.com)
In contrast, the primary abnormality in dehydrated hereditary stomatocytosis is a change in the relative membrane permeability to K + . Efflux of K + is increased 2-fold to 4-fold and results in cation depletion, with decreased intracellular osmolality and water loss. (medscape.com)

Upon prolonged high intracellular rises in Ca 2+ , platelets develop a procoagulant phenotype that is characterized by the surface membrane exposure of phosphatidylserine and by the inactivation of integrin α IIb β 3 (procoagulant platelet population) ( 5 ). (frontiersin.org)

Cell membrane glycoproteins that form channels to selectively pass chloride ions. (nih.gov)
Recent investigations have suggested distinct molecular determinants responsible for agonist binding and channel opening for transmembrane flux of sodium, calcium and potassium ions. (gozmusic.org)
During the generation of action potentials, sodium ions move across the membrane through voltage-gated ion channels. (medscape.com)
By transporting Na + and K + ions across the cell membrane, red cells can adjust the intracellular concentration of these cations and regulate intracellular hydration. (medscape.com)

These are selectively and variably permeable ion channels. (medscape.com)

We provide a comprehensive overview of the proteases acting on the platelet membrane. (frontiersin.org)
The process of thrombus formation is considered to be initiated by von Willebrand factor (VWF) binding to exposed collagen or laminin in the damaged vessel wall, followed by shear-dependent platelet binding to VWF through the glycoprotein (GP)Ib-V-IX complex ( 1 , 3 , 4 ). (frontiersin.org)

This gene encodes one member of the sodium channel alpha subunit gene family. (nih.gov)

Endocytosis is a form of active transport where a cell takes in molecules, using the plasma membrane, and packages them into vesicles. (wikipedia.org)
Cholesterol in Cell Membrane The phospholipid bilayer also contains cholesterol molecules. (slideshare.net)
These molecules form small- and large-scale clusters in the membrane of human lymphocytes. (unideb.hu)
Lipids are important molecules that often make up membranes in the cell. (knowt.com)
Allows large or charged molecules to cross the cell membrane (water, glucose). (knowt.com)

Potassium channels whose activation is dependent on intracellular calcium concentrations. (harvard.edu)
With HyperPP fast channel inactivation, mutations are usually situated in the inner parts of transmembrane segments or in the intracellular loops affecting the docking sites for the fast inactivating particle, thus impairing fast channel inactivation leading to persistent Na + current. (medscape.com)
Erythrocytes have intracellular hemoglobin, 2-3,diphosphoglycerate (2,3-DPG), and ATP, which all exert osmotic pressure across the semipermeable cell membrane. (medscape.com)

NAV1.7 Voltage-Gated Sodium Channel" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings) . (ucdenver.edu)
A voltage-gated sodium channel subtype found widely expressed in nociceptive primary sensory neurons. (ucdenver.edu)
Defects in the SCN9A gene, which codes for the alpha subunit of this sodium channel, are associated with several pain sensation-related disorders. (ucdenver.edu)
This graph shows the total number of publications written about "NAV1.7 Voltage-Gated Sodium Channel" by people in this website by year, and whether "NAV1.7 Voltage-Gated Sodium Channel" was a major or minor topic of these publications. (ucdenver.edu)
Below are the most recent publications written about "NAV1.7 Voltage-Gated Sodium Channel" by people in Profiles. (ucdenver.edu)
Defects in the SCN2A gene which codes for the alpha subunit of this sodium channel are associated with benign familial infantile seizures type 3, and early infantile epileptic encephalopathy type 11. (rush.edu)
ensHS ens Amiloride-sensitive sodium channel delta-subunit (Epithelial Na+ ENSP00000305976 ENSG00000170145 ensHS ens salt-inducible kinase 2. (web.app)
Voltage-gated sodium channel subunits that play a role in the assembly, expression, and functional modulation of the sodium channel. (nih.gov)
They form a heterotrimeric complex with the pore-forming sodium channel alpha subunits. (nih.gov)
From a physiological and pathophysiological point of view, the conformational states of the sodium channel during heart function constitute a significant aspect for the diagnosis and treatment of heart diseases. (bvsalud.org)
Functional states of the sodium channel (closed, open, and inactivated) and their structure help to understand the cardiac regulation processes. (bvsalud.org)
Heart relaxation also stands out as an active process, dependent on the energetic output and on specific ion and enzymatic actions, with the role of sodium channel being outstanding in the functional process. (bvsalud.org)
Finally, it seems appropriate to consider the "sodium channel syndrome" (mutations in the gene of the α subunit of the sodium channel, SCN5A gene) as a single clinical entity that may manifest in a wide range of phenotypes, to thus have a better insight on these cardiac syndromes and potential outcomes for their clinical treatment. (bvsalud.org)

Monomeric C9 (mC9) binds the C5b-8 complex to form C5b-9 which catalyzes the polymerization of C9 forming C5b-p9 (MEMBRANE ATTACK COMPLEX) and transmembrane channels leading to lysis of the target cell. (umassmed.edu)

2015). Sodium/bile acid cotransporters are integral membrane glycoproteins that participate in the enterohepatic circulation of bile acids. (web.app)

The verify incorporates colloid gold conjugate pad and a membrane strip pre-coated with antibodies specific to SARS-CoV-2 antigen on the verify traces (T). (apiculture-wallonie.be)

Rational Laboratory Diagnostics of Antiphospholipid Antibodies: Anti-Cardiolipin, Anti-β2-Glycoprotein I, Anti-Prothrombin and Anti-Annexin V Antibodies. (ncbcs.org)
A attainable co-appearance of anticardiolipin (aCL), anti-β2-glycoprotein I (anti-β2-GPI), anti-prothrombin (aPT) and anti-annexin V (aANXV) antibodies of IgG, IgM and IgA class have been studied in 58 sufferers with SLE alone and 32 sufferers APS within the view of rational laboratory diagnostics. (ncbcs.org)

There are different ways through which cells can transport substances across the cell membrane. (wikipedia.org)

The resting muscle fiber membrane is polarized primarily by the movement of chloride through chloride channels and is repolarized by movement of potassium. (medscape.com)

139-140 In phagocytosis, a cell surrounds particles including food particles through an extension of the pseudopods, which are located on the plasma membrane. (wikipedia.org)
139-140 In pinocytosis, a cell takes in ("gulps") extracellular fluid into vesicles, which are formed when plasma membrane surrounds the fluid. (wikipedia.org)
Using a human cortical neuronal (HCN) culture system, we showed that full-length APP is targeted to both mitochondria and plasma membrane (PM) by virtue of N-terminal chimeric signals. (jneurosci.org)
This adds considerably to the selective nature of plasma membranes. (iprep.kz)
Plasma membrane. (iprep.kz)
It is the terminal component of a respiratory chain that transfers single electrons from cytoplasmic NADPH across the plasma membrane to molecular oxygen on the exterior. (lu.se)

Unlike the other NHE isoforms, NHE3 is recycled between apical membranes and the endosomal compartment of epithelial cells where it has a significant involvement in renal and intestinal Na + absorption. (tocris.com)

Voltage-sensitive ion channels closely regulate generation of action potentials (brief and reversible alterations of the voltage of cellular membranes). (medscape.com)

Voltage-Gated Sodium Channels Q C V Voltage (mV) 16 8 Charge (pC) 0. (binaryoptionsforex625.com)
Voltage-gated sodium channels function in the generation and propagation of action potentials in neurons and muscle. (nih.gov)

Effects of calcium-activated potassium channel modulators on afterhyperpolarizing potentials in identified motor and mechanosensory neurons of the medicinal leech. (harvard.edu)

A 63-kDa serum glycoprotein encoded by gene C9. (umassmed.edu)

The Rh antigens appear to exist as a multisubunit complex of CD47 (MIM 601028), LW (MIM 111250), glycophorin B (MIM 111740), and play a critical role in the Rh50 glycoprotein. (novusbio.com)
CD59 restricts the cytolytic activity of homologous complement by binding to C8 and C9 and blocking the assembly of the membrane attack complex. (bvsalud.org)

Potassium Channels, Calcium-Activated" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings) . (harvard.edu)
This graph shows the total number of publications written about "Potassium Channels, Calcium-Activated" by people in Harvard Catalyst Profiles by year, and whether "Potassium Channels, Calcium-Activated" was a major or minor topic of these publication. (harvard.edu)
Below are the most recent publications written about "Potassium Channels, Calcium-Activated" by people in Profiles. (harvard.edu)
Discovery of Novel Activators of Large-Conductance Calcium-Activated Potassium Channels for the Treatment of Cerebellar Ataxia. (harvard.edu)

Prokaryotes have DNA located in an area called the nucleoid, which is not separated from other parts of the cell by a membrane. (wikipedia.org)
Enables them to be embedded in the nonpolar (hydrophobic) area of the membrane  Polar regions are anchored in the water  Provide CHANNELS into the cell but only for selected items. (slideshare.net)
The cell membrane is a semi-permeable bilayer. (knowt.com)
Prevents the cell membrane from becoming too solid or too liquid. (knowt.com)
In order to trigger a response, these signals must be transmitted across the cell membrane. (everythingask.com)
This inhibition reflects the association of Caspr with contactin during biosynthesis and the resulting expression of a low molecular weight (LMw), endoglycosidase H-sensitive isoform of contactin at the cell membrane, which remains associated with Caspr but is unable to bind NF155. (rupress.org)

Liddle syndrome is an autosomal dominant form of hypertension, resulting from mutations in the cytoplasmic C-terminus of either the beta or gamma subunits of the amiloride-sensitive epithelial Na channel (ENaC) which lead to constitutively increased channel activity. (nih.gov)
To address this question, we have performed a systematic mutagenesis study of the C-termini of the alpha, beta and gamma ENaC subunits of the rat channel and have analyzed their function by expression in Xenopus oocytes. (nih.gov)
Missense mutations altering a consensus PPPXY sequence of the alpha, beta or gamma subunits reproduced the increase in channel activity found in mutants in which the entire cytoplasmic C-termini are deleted. (nih.gov)

Also functions as a voltage-gated proton channel that mediates the H+ currents of resting phagocytes. (lu.se)

In channels, they move down an electrochemical gradient to produce electrical signals. (wikipedia.org)

Wang ZJ, Tabakoff B, Levinson SR, Heinbockel T. Inhibition of Nav1.7 channels by methyl eugenol as a mechanism underlying its antinociceptive and anesthetic actions. (ucdenver.edu)

Small glycoproteins found on both hematopoietic and non-hematopoietic cells. (bvsalud.org)
NTCP and ASBT are cotransporters that mediate sodium-dependent, electrogenic uptake of mainly bile salts into hepatocytes (NTCP), biliary epithelial cells, ileal enterocytes and renal proximal The importance of membrane voltage in uptake of bile salts into hepatocytes is not known. (web.app)
P-gp (P-glycoprotein) is a ATP-binding cassette transproters which overepxressed in multidrug-resistance cancer cells. (apexbt.com)

The results demonstrate that a short proline-rich segment present in the cytoplasmic C-terminus of each subunit is required for the normal regulation of channel activity. (nih.gov)
The β-secretase cuts APP first to generate the N terminus of Aβ, thus producing a membrane bound C-terminal fragment called C99. (jneurosci.org)

HN - 2008 MH - Superior Sagittal Sinus UI - D054063 MN - A07.231.908.224.667 MS - The long large endothelium-lined venous channel on the top outer surface of the brain. (bvsalud.org)

The molecular defects that transform AE1 into a cation channel are currently under investigation. (medscape.com)

In cytoplasm, endoplasmic reticulum (ER) synthesizes[clarification needed] membranes and performs other metabolic activities. (wikipedia.org)
Sequential mannose trimming of N -glycan, from M9 to M8B and then to oligosaccharides exposing the α1,6-linked mannosyl residue (M7A, M6, and M5), facilitates endoplasmic reticulum-associated degradation of misfolded glycoproteins (gpERAD). (elifesciences.org)

The xerocytes formed are shear-sensitive and prone to membrane fragmentation in response to metabolic stress, with subsequent hemolysis. (medscape.com)

This new regulatory mechanism of channel function is critical for the maintenance of normal Na reabsorption in the kidney and of Na+ balance and blood pressure. (nih.gov)

El càncer de pulmó de cèl·lula no petita (CPCNP) es pot definir a nivell molecular per les alteracions genètiques que es produeixen en múltiples oncogens, inclosos els reordenaments dels gens ALK i ROS1. (tesisenred.net)

HN - 2008 BX - Lateral Sinus MH - Atrial Septum UI - D054087 MN - A07.541.459.249 MS - The thin membrane-like muscular structure separating the right and the left upper chambers (HEART ATRIA) of a heart. (bvsalud.org)

Anatomy30

Organisms18

Diseases2

Chemicals and Drugs142

Analytical, Diagnostic and Therapeutic Techniques and Equipment21

Phenomena and Processes38

Disciplines and Occupations2

Technology, Industry, Agriculture5

Information Science4

Health Care1

Proteins24

Receptor11

Protein18

Glycolipids3

Transporters3

Receptors5

Complexes4

Permeability5

Surface membrane1

Ions4

Selectively1

Platelet2

Gene encodes1

Molecules5

Intracellular3

Sodium Channel13

Binds1

Integral1

Antigen1

Antibodies2

Substances1

Chloride1

Plasma6

Endosomal1

Cellular1

Voltage-Gated Sodium Channels2

Potentials1

Serum1

Complex2

Potassium Channels4

Cell6

Subunits3

Mediates1

Electrochemical gradient1

Inhibition1

Cells3

Terminus2

Outer1

Defects1

Endoplasmic2

Metabolic1

Mechanism1

Molecular1

Lateral1