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Heparitin SulfateDermatan SulfateSulfatesHeparan Sulfate ProteoglycansChondroitin Sulfate ProteoglycansKeratan SulfateChondroitin SulfatesDextran SulfatePolymerase Chain ReactionSodium Dodecyl SulfateGlycosaminoglycansMolecular Sequence DataMagnesium SulfateAmmonium SulfateProteoglycansImmunoglobulin Light ChainsSulfotransferasesImmunoglobulin Heavy ChainsAmino Acid SequenceCopper SulfateChondroitinZinc SulfateDehydroepiandrosterone SulfateMolecular WeightDisaccharidesCalcium SulfateSulfuric Acid EstersMyosin Heavy ChainsChondroitinases and Chondroitin LyasesBase SequenceKineticsElectrophoresis, Polyacrylamide GelSulfate AdenylyltransferaseMyosin Light ChainsReverse Transcriptase Polymerase Chain ReactionSulfuric AcidsHeparinOligosaccharidesChondroitin LyasesSulfatasesHeparin LyaseCattleProtein BindingChromatography, GelSulfur RadioisotopesBinding SitesIduronic AcidPolysaccharide-LyasesRNA, MessengerAmino AcidsPhosphoadenosine PhosphosulfateCells, CulturedChromatography, Ion ExchangeChondroitin ABC LyaseCell LineMacromolecular SubstancesGlucosamineIndicanProtein ConformationChromatography, High Pressure LiquidHydrogen-Ion ConcentrationSubstrate SpecificityCarbohydrate ConformationModels, MolecularCloning, MolecularMutationSyndecansRecombinant ProteinsPeptide FragmentsSulfurNitrous AcidMyosinsSulfur IsotopesChromatography, AffinityMagnetic Resonance SpectroscopySyndecan-1RabbitsCarbohydrate SequenceEscherichia coliSequence Homology, Amino AcidDNA PrimersCarbohydratesGlucuronidaseCartilage

HeparinHeparan sulfate proteoglycanGlycosaminoglycanChondroitinHeteropolysaccharideGlycansCell surfaceEnzymesInteractionsProtein

Heparin2

• Heparin and related substances, including glycosaminoglycans, chondroitin, low-molecular-weight heparin (LMWH), heparinoids, heparitin sulfate, hyaluronic acid and keratan sulphate, have been demonstrated a few positive effects on delaying the progression of diabetic kidney disease (DKD). (cochrane.org)
• The children who afflict with Sanfilippo Syndrome miss an essential enzyme that breaks down strings of complex body sugar called heparin sulphate. (syndromespedia.com)

Heparan sulfate proteoglycan1

• The presence of the glycosaminoglycan side chains of heparan sulfate proteoglycan, an important constituent of the glomerular basement membrane, is decreased in DKD proportionally to the increasing degree of proteinuria. (cochrane.org)

Glycosaminoglycan2

• In our body's cells, Heparan Sulfate Proteoglycans (Proteoheparan Sulfate) , as ubiquitous proteoglycan macromolecules , consisting of a core protein to which, the glycosaminoglycan heparan sulfate (heparitin sulfate) chains, are attached and held, associated with the cell surface and extracellular matrix of a wide range of tissue cells. (wellnessadvocate.com)
• The protein contains a single glycosaminoglycan chain and is similar in structure to BIGLYCAN. (lookformedical.com)

Chondroitin9

• EC 4.2.2.4 acts on chondroitin sulfate A and C as well as on dermatan sulfate and slowly on hyaluronate. (lookformedical.com)
• EC 4.2.2.5 acts on chondroitin sulfate A and C. (lookformedical.com)
• Derivatives of chondroitin which have a sulfate moiety esterified to the galactosamine moiety of chondroitin. (lookformedical.com)
• Chondroitin sulfate A, or chondroitin 4-sulfate, and chondroitin sulfate C, or chondroitin 6-sulfate, have the sulfate esterified in the 4- and 6-positions, respectively. (lookformedical.com)
• DERMATAN SULFATE) is a misnomer and this compound is not a true chondroitin sulfate. (lookformedical.com)
• It differs from CHONDROITIN SULFATE A (see CHONDROITIN SULFATES) by containing IDURONIC ACID in place of glucuronic acid, its epimer, at carbon atom 5. (lookformedical.com)
• Proteoglycans consisting of proteins linked to one or more CHONDROITIN SULFATE-containing oligosaccharide chains. (lookformedical.com)
• Enzymes which catalyze the elimination of glucuronate residues from chondroitin A,B, and C or which catalyze the hydrolysis of sulfate groups of the 2-acetamido-2-deoxy-D-galactose 6-sulfate units of chondroitin sulfate. (lookformedical.com)
• In this work, we isolated two new sulfated glycans from the body wall of the sea cucumber Thyonella gemmata: one fucosylated chondroitin sulfate (TgFucCS) (17.5 ± 3.5% kDa) and one sulfated fucan (TgSF) (383.3 ± 2.1% kDa). (bvsalud.org)

Heteropolysaccharide1

• In our body, Heparitin Sulfate (Heparan Sulfate) is a heteropolysaccharide that accumulates in individuals with the dis-ease process mucopolysaccharidosis . (wellnessadvocate.com)

Glycans1

• Sulfated glycans inhibited both binding and uptake of rods, probably by competing with the binding of rods to cellular HS. (huji.ac.il)

Cell surface2

• These results suggested that the cell surface receptor of prion rods involves sulfated HS chains. (huji.ac.il)
• Efficient infection by HPV16 and HPV18 pseudovirions requires interactions of particles with cell-surface receptor heparan sulfate oligosaccharide. (nih.gov)

Enzymes2

• Inside tumors PMN-MDSCs expressed heparan sulfate biogenesis enzymes at higher levels. (utmb.edu)
• Sanfilippo syndrome occurs when enzymes that are needed to break down the heparan sulphate sugar chain are either defective or missing entirely. (syndromespedia.com)

Interactions2

• In our body's cells, Heparan Sulfate Proteoglycans (HSPG) are essential cofactors in cell-matrix adhesion processes, in cell-cell recognition systems, and in receptor-growth factor interactions. (wellnessadvocate.com)
• These results provide a basis for understanding virus-heparan sulfate receptor interactions critical for HPV infection and for the potential development of inhibitors against HPV infection. (nih.gov)

Protein2

• We have previously shown that cellular heparan sulfates (HS) are involved in the ongoing formation of scrapie prion protein (PrP Sc ) in chronically infected cells. (huji.ac.il)
• We have previously shown that cellular heparan sulfates (HS) are involved in the ongoing formation of scrapie prion protein (PrPSc) in chronically infected cells. (huji.ac.il)