• commonly
  • Several symptoms are commonly associated with bruxism, including hypersensitive teeth, aching jaw muscles, headaches, tooth wear, and damage to dental restorations (e.g. crowns and fillings) to teeth. (wikipedia.org)
  • nerve
  • Chang CC, Chuang ST, Lee CY, Weio JW (1972) Role of cardiotoxin and phospholipase A in the blockade of nerve conduction and depolarization of skeletal muscle induced by cobra venom. (springer.com)
  • contraction
  • This allows Na + and Ca 2+ ions to enter the cell and K + ions to leave the cell, causing a depolarization of the end plate, resulting in muscle contraction. (wikipedia.org)
  • Alternatively, depolarizing agents, such as succinylcholine , are nicotinic receptor agonists which mimic Ach, block muscle contraction by depolarizing to such an extent that it desensitizes the receptor and it can no longer initiate an action potential and cause muscle contraction. (wikipedia.org)
  • occur
  • Following treatment with TranquiVed (xylazine), the heart rate is decreased and a transient change in the conductivity of the cardiac muscle may occur, as evidenced by a partial atrioventricular block. (drugs.com)
  • multiple sclerosis
  • Tumefactive multiple sclerosis is a condition in which the central nervous system of a person has multiple demyelinating lesions with atypical characteristics for those of standard multiple sclerosis (MS). It is called tumefactive as the lesions are "tumor-like" and they mimic tumors clinically, radiologically and sometimes pathologically. (wikipedia.org)
  • cause
  • The generation of the neuronal signals in motor neurons that cause muscle contractions are dependent on the balance of synaptic excitation and inhibition the motor neuron receives. (wikipedia.org)
  • mechanism
  • Search for the exact mechanism of action is ongoing but limited due to the existence of more-effective safe muscle relaxers (ex. (wikipedia.org)