Cells gonads. Medical search. Frequent questions

In the developing male (XY) gonad, sex-determining region of the Y (SRY) protein acts to up-regulate expression of the related gene, SOX9 , a transcriptional regulator that in turn initiates a downstream pathway of testis development, whilst also suppressing ovary development. (plos.org)
Analysis of XY byg/byg gonads at 11.5 d post coitum reveals a growth deficit and a failure to support mesonephric cell migration, both early cellular processes normally associated with testis development. (plos.org)
In mammals, whether an individual develops as a male or female depends on its sex chromosome constitution: those with a Y chromosome become males because of the development of the embryonic gonad into a testis. (plos.org)
Our data indicate, for the first time, a requirement for MAPK signaling in the developing XY gonad in order to facilitate normal expression of SRY and the downstream testis-determining genes and also suggest that reduced dosage of MAP3K4 may be the cause of a previously described autosomal sex-reversing mutation in the mouse. (plos.org)
Bagamang sa agham, ang katawagang "gonad" ay maaaring tumukoy sa panlalaking gonad ( testis ) o kaya sa pambabaeng gonad (mga obaryo ), ang gonad sa bernakular o salitang-kanto ay tumutukoy lamang sa itlog ng bayag o testis. (wikipedia.org)
Steroid-producing cells in the interstitial tissue of the TESTIS. (umassmed.edu)
In this study, we evaluated the effect of heat stress (HS) on the development of cells secreting major reproductive hormones of the HPG axis (i.e., hypothalamus, pituitary gland, ovary, and testis) of Wenchang chicks. (scielo.br)
The gonads present may be bilateral ovotestes, or they may be a combination of a unilateral ovary or testis with an ovotestis on the contralateral side. (medscape.com)

Gonads (testes and ovaries) from adult insects (occa- sionally fifth-stage nymphs) were removed, fixed in ethano-acetic acid (3:1), and stored at -20°C. C-banding treatment was carried out on air-dried squash, as previous- ly described (13). (cdc.gov)
Most germ cell tumors appear in the ovaries ( ovarian tumors ) or testes ( testicular tumors ), but they can also get "trapped" in the brain during the fetal period. (dana-farber.org)
When cells that are meant to form sperm in the testicles or eggs in the ovaries travel to other parts of the body, they may grow into extragonadal germ cell tumors . (vicc.org)
Extragonadal germ cell tumors form in parts of the body other than the gonads (testicles or ovaries). (vicc.org)
LH then travels to your gonads (testicles or ovaries) and stimulates the production and release of testosterone. (clevelandclinic.org)
These cells later become sperm in the testicles or eggs in the ovaries. (cigna.com)
Gonadal germ cell tumors form in the gonads (testicles and ovaries). (cigna.com)
Members of the evolutionarily conserved Nanos gene family are preferentially expressed in the ovaries and are known to play an important role in germ cell development, maintenance, and survival [ 24 - 30 ]. (hindawi.com)

SOX9 is involved in the formation of testes from the indifferent fetal gonads. (thermofisher.com)

The female gonad, the ovary, produces egg cells. (wikipedia.org)
This work evaluated the effect of ex situ management on neurogenesis (cell proliferation in the dorsal and medial ventricular zones, neuronal integration in the dorsomedial and medial cortices), ovary cell proliferation, body size (mass and length) and self-righting ability. (frontiersin.org)

5. The technique of producing such germ line chimaeras is of value in studying cell kinetics, gonad differentiation and the production of transgenics. (reading.ac.uk)
He gonad throughout granulosa cell differentiation (Pyroptosis Accession Figure 1B). (bet-bromodomain.com)
Via genetic and chemical models, the team was able to propose that the deleterious effects of bisphenols on mature oocytes results from their ability to induce oxidative lesions on DNA at a key step in germinal cell differentiation during the fetal period. (cea.fr)
Wu X, Zhang N, Lee MM. Mullerian inhibiting substance recruits ALK3 to regulate Leydig cell differentiation. (umassmed.edu)
SOX9 has a role in sex determination and differentiation of Sertoli cells. (thermofisher.com)
Despite significant advances in understanding nephron segment patterning, many questions remain about the underlying genes and signaling pathways that orchestrate renal progenitor cell fate choices and regulate differentiation. (mdpi.com)
Our studies also suggest that these hESC reporter lines will become valuable for investigators working on optimizing stem cell differentiation and culture for other tissues, as many of these reporter genes are not only restricted to HSC. (ca.gov)
These lines will serve as tools to identify factor combinations to improve the in vitro differentiation of hESCs to functional blood stem cells. (ca.gov)
Stem and progenitor cell populations are often heterogeneous, which may reflect stem cell subsets that express subtly different properties, including different propensities for lineage selection upon differentiation, yet remain able to interconvert. (lu.se)
A key challenge is to understand how state, but must also afford flexibility in cell-fate choice to permit the different cell-fate options confronting stem and progenitor cell-type diversification and differentiation in response to cells are selected and coordinated such that adoption of a given intrinsic cues or extrinsic signals. (lu.se)
Evidence the fate of stem cells has broad ramifications for biomedical suggests that during development or differentiation, cells make science from elucidating the causes of cancer to the use of very precise transitions between apparently stable ``network stem cells in regenerative medicine. (lu.se)

However, the comprehensive chromatin state has not yet been analyzed for human fetal germ cells (FGCs). (nature.com)
Here we use nucleosome occupancy and methylation sequencing method to analyze both the genome-wide chromatin accessibility and DNA methylome at a series of crucial time points during fetal germ cell development in both human and mouse. (nature.com)
Usually, germ cells migrate to the gonads during fetal development. (dana-farber.org)
Wu X, Wan S, Lee MM. Key factors in the regulation of fetal and postnatal Leydig cell development. (umassmed.edu)

Testicles are the gonads (sex organs) in people assigned male at birth (AMAB). (clevelandclinic.org)
More specifically, the Leydig cells in your testicles make testosterone. (clevelandclinic.org)

Gonads start developing as a common primordium (an organ in the earliest stage of development), in the form of genital ridges, which are only later differentiated to male or female sex organs (except when they are not differentiated). (wikipedia.org)
The development of the gonads is a part of the development of the urinary and reproductive organs. (wikipedia.org)
Both systems have gonads that produce (sperm and egg or ovum) and sex organs. (wikibooks.org)
And both systems experience maturation of their reproductive organs, which become functional during puberty as a result of the gonads secreting sex hormones. (wikibooks.org)
Germ cell tumors most commonly appear in the gonads (sex organs). (childrensoncologygroup.org)
At about four weeks, the earliest germ cells in the growing fetus migrate from their point of origin to the gonadal area (the area of the sex organs). (childrensoncologygroup.org)
A procedure in which a sample of blood is examined to measure the amounts of certain substances released into the blood by organs, tissues , or tumor cells in the body. (vicc.org)
In brief, HS caused dysfunction of the corresponding target organs of the HPG axis in Wenchang chicks, and this affected the normal growth and development of the cells' HPG axis. (scielo.br)
They stimulate reproductive organs, germ cell maturation, and the secondary sex characteristics in the males and the females. (bvsalud.org)
The endocrine system consists of endocrine glands that produce and secrete hormones into the blood stream to reach and act on target cells of specific organs. (medscape.com)

Doctors discovered she had a teratoma, a type of tumor that can contain all three of the major cell types that are found in an early stage human embryo. (livescience.com)
Because teratomas can have all three of the cell types found in the developing embryo, they can contain a variety of tissues, including cartilage, bone and hair, said Dr. Amir Dehdashti, director of cerebrovascular neurosurgery research at North Shore University Hospital in Manhasset, New York. (livescience.com)
Typically, during the development of a human embryo, germ cells migrate to the gonads. (livescience.com)

The GnRH secreted from the hypothalamus activates specific receptors on the pituitary gland to stimulate the synthesis and secretion of FSH and LH from gonadotropic cells of the pituitary gland. (scielo.br)

The gonads are controlled by luteinizing hormone (LH) and follicle-stimulating hormone (FSH), produced and secreted by gonadotropes or gonadotrophins in the anterior pituitary gland. (wikipedia.org)
Ang mga gonad ay panghormonang kinukontrol ng hormonang nagpapadilaw ( luteinizing hormone o LH) at ng hormonang pang-estimula ng polikula ( FSH ) na kinakatas ng anteryor na glandulang pituwitaryo . (wikipedia.org)
Immediately prior to ovulation, the combination of E 2 and FSH leads to the production of luteinizing-hormone (LH) receptors on the granulosa cells surrounding the lead follicle. (medscape.com)

A gonad, sex gland, or reproductive gland is a mixed gland that produces the gametes and sex hormones of an organism. (wikipedia.org)
Hypogonadism is the condition in which the production of sex hormones and germ cells (sperm and eggs) is inadequate. (encyclopedia.com)
The endocrine system consists of specialized groups of cells called glands that make, store, and release regulating chemicals called hormones directly into the bloodstream to regulate how the body functions. (cdc.gov)
Steroid hormones produced by the GONADS. (bvsalud.org)
It produces 2 hormones: vasopressin, which causes blood pressure to rise and regulates the amount of water in the body's cells, and oxytocin, which causes the uterus to contract during childbirth and lactation to begin. (medscape.com)
These hormones regulate the body's growth, and are involved in cell to cell communication, control metabolic activity, sleep-wake homeostasis, and altered regulation or dysregulation of adaptive response in various physiologic and pathophysiologic states. (medscape.com)

Researchers don't know the cause of germ cell tumors. (dana-farber.org)
The exact cause of germ cell tumors is not completely understood. (childrensoncologygroup.org)

4. Quantitative histology of 6-d embryos showed that busulphan produced 75% sterilisation but that PGCs could repopulate these gonads. (reading.ac.uk)
Ovotestis refers to the histology of a gonad that contains both ovarian follicles and testicular tubular elements. (medscape.com)

Childhood extracranial germ cell tumors are grouped as gonadal or extragonadal extracranial tumors. (cigna.com)
Moreover, we describe experiments showing the presence of activated MKK4, a direct target of MAP3K4, and activated p38 in the coelomic region of the XY gonad at 11.5 d post coitum, establishing a link between MAPK signalling in proliferating gonadal somatic cells and regulation of Sry expression. (plos.org)
Further, DMY knock-down and estradiol-17b (E2) treatment, to determine the possible function of DMY during early gonadal sex differ- entiation in XY medaka, revealed that the mitotic and meiotic activities of the germ cells in the 0 day after hatching (dah) DMY knock-down XY larvae were identical to that of the normal XX larvae. (amrita.edu)
A quantitative histological analysis of the parasitized gonads demonstrated a significant decrease in gonadal area, in the size of individual acini, and in the numbers of differentiated germ cells compared to unparasitized clams. (int-res.com)

Testicular germ cell tumors usually occur before the age of 4 years or in adolescents and young adults. (cigna.com)
Testicular germ cell tumors in adolescents (11 years and older) and young adults are different from those that form in early childhood. (cigna.com)
Balasinor NH, D'Souza R, Nanaware P, Idicula-Thomas S, Kedia-Mokashi N, He Z, Dym M. Effect of high intratesticular estrogen on global gene expression and testicular cell number in rats. (umassmed.edu)
A diagnosis of OT-DSD is based solely on the presence of ovarian and testicular tissue in the gonad and not on the characteristics of the internal and external genitalia, even if ambiguous. (medscape.com)

Female reproductive cells are egg cells, and male reproductive cells are sperm. (wikipedia.org)
The researchers compared the genomes of M. belari 's germline cells - the specialized reproductive cells like sperm and eggs - with the genomes of the worm's somatic (nonreproductive) cells. (lifeboat.com)
These are the processes of cell division that involve the formation of either new body cells (mitosis) or new reproductive cells in the gonads (meiosis). (cdc.gov)

2. Some of these embryos were injected with primordial germ cells (PGCs) after 55 h of incubation to attempt to repopulate the gonads. (reading.ac.uk)
As judged by the TUNEL assay (See Text S1), some SSEA1-positive PGCs undergoing cell death had been detected in E9.0 hindgut endoderm (Figure 2C). (bet-bromodomain.com)
This time window correlates with an epigenetic transition of PGCs and cell cycle arrest involving E7.5-E9.5 [3,11].Loss of Mad2l2 deficient PGCs is caused by an intrinsic failureProper development of PGCs relies on their endogenous system as well as on exogenous signals emanating from surrounding somatic cells that assistance their induction, migration or survival in many organisms [414]. (bet-bromodomain.com)
The identification of an inactivating missense mutation in NANOS3 suggests a mechanism for POI involving increased primordial germ cells (PGCs) apoptosis during embryonic cell migration and highlights the importance of NANOS proteins in human ovarian biology. (hindawi.com)
Three Nanos homologues exist in mouse, with Nanos2 and Nanos3 functioning primarily in male germ cell development and maintaining PGCs viability, respectively [ 33 , 34 ]. (hindawi.com)
In mice, Nanos3 is expressed in the primordial germ cells (PGCs) from their formation until shortly after their appearance in the gonads (E13.5 in female and E14.5 in male embryos) [ 24 ]. (hindawi.com)

Germ cells get their name because they normally produce the specialized cells that create life: sperm and egg cells - the sex cells needed for reproduction. (childrensoncologygroup.org)

Emigration to the dorsal mesentery did not occur, and consequently, gonad PRMT3 Gene ID primordia at E13.5 were devoid of germ cells (Figure 2A). (bet-bromodomain.com)

Depending on their size we suspected them to become germ cells having lost already expression of their standard marker, although we couldn't exclude that they represented mutant somatic cells. (bet-bromodomain.com)
In reality, gene somatic cells to a pluripotent cell state by a handful of transcrip- expression is graded, making the potential gene expression tion factors (Takahashi and Yamanaka, 2006). (lu.se)

The male gonad, the testicle, produces sperm in the form of spermatozoa. (wikipedia.org)
In the human reproductive process, two kinds of sex cells ( gametes), are involved: the male gamete (sperm), and the female gamete (egg or ovum). (wikibooks.org)
Nevertheless, it negatively affects the ontogenesis of male gonads and brain areas homologous to the mammalian hippocampus, as well as body size and fitness. (frontiersin.org)
In the 9th month of the study, a cross-mating of the animals was performed, male gonads were evaluated and embryotoxic effects were examined. (europa.eu)

In applying bioanalytical approaches, the aim of this study was to determine the toxicity of contaminants derived from a solid waste dumpsite in Calabar (Nigeria), by investigating the alterations of lipid and estrogen signaling pathways in Poeciliopsis lucida hepatocellular carcinoma-1 (PLHC-1) cells and compared to in vivo African catfish (Clarias gariepinus), using polar, nonpolar and elutriate extraction methods. (bvsalud.org)
The multi-omics analyses of acsl1 reveal its translational significance as a tumor microenvironmental and prognostic biomarker in clear cell renal cell carcinoma. (cdc.gov)

Successfully treating your child's germ cell tumor depends on identifying the tumor type and location. (dana-farber.org)
Depending on the germ cell tumor type, we may recommend further surgery to remove as much of the tumor as possible. (dana-farber.org)
After a germ cell tumor is diagnosed, doctors need to assess how advanced it is, which is called staging the tumor. (childrensoncologygroup.org)

Some hermaphroditic animals (also some humans) have a type of gonad called an ovotestis. (wikipedia.org)

[ 2 ] Germ cell tumors can be benign or malignant. (medscape.com)
Malignant germ cell tumors are subdivided into seminomas and nonseminomatous tumors. (medscape.com)
Nonseminomatous tumors also are termed malignant teratomas and are divided further by cell type into choriocarcinomas, embryonal carcinomas, mixed tumors, teratocarcinomas, and yolk sac carcinomas. (medscape.com)
Malignant germ cell tumors include several types of cancer, such as immature teratoma, yolk sac tumor and choriocarcinoma. (childrensoncologygroup.org)
Although not as difficult to treat as malignant tumors, benign germ cell tumors can cause problems because of their size. (childrensoncologygroup.org)
These are more common than malignant extragonadal germ cell tumors and often are very large. (vicc.org)
Malignant extragonadal germ cell tumors are divided into two types, nonseminoma and seminoma . (vicc.org)
Malignant extragonadal germ cell tumors may cause signs and symptoms as they grow into nearby areas. (vicc.org)
A PET scan is a procedure to find malignant tumor cells in the body. (vicc.org)
Malignant tumor cells show up brighter in the picture because they are more active and take up more glucose than normal cells do. (vicc.org)
Childhood extracranial germ cell tumors may be benign or malignant. (cigna.com)
Malignant extracranial germ cell tumors are tumors that form outside the brain. (cigna.com)

In C. elegans, cogc-8 is involved in gonad morphogenesis and regulation of cell migration. (wormbase.org)
It has a transcriptional regulation in melanin production in cells. (thermofisher.com)
In terminally differentiated cell fate is coupled to appropriate regulation of the alternative cells, transcriptional networks must be stable and irreversible, pathways. (lu.se)

Benign germ cell tumors are referred to as benign teratomas or dermoids if they are primarily solid in consistency. (medscape.com)
The vast majority of teratomas and other germ cell tumors arise in the anterior compartment of the mediastinum. (medscape.com)
Teratomas are what can result if these germ cells end up in the wrong place, according to the Dana-Farber Cancer Institute . (livescience.com)
Among brain tumors , just 0.5 to 3 percent are germ cell tumors, and of these, about 20 percent are teratomas, Dehdashti said. (livescience.com)
There are several sub-types of non-germinomatous germ cell tumors, including teratomas, choriocarcinomas, endodermal sinus tumors (yolk sac tumors), embryonal carcinomas, and mixed tumors. (dana-farber.org)
Benign germ cell tumors include certain kinds of teratomas. (childrensoncologygroup.org)
Benign extragonadal germ cell tumors are called benign teratomas . (vicc.org)
Most ovarian germ cell tumors are benign mature teratomas (dermoid cysts). (cigna.com)

3. Primordial germ cells transfected with a defective retrovirus containing the reporter gene lac Z were shown to settle in these sterilised gonads. (reading.ac.uk)
Chromatin remodeling is important for the epigenetic reprogramming of human primordial germ cells. (nature.com)

Leydig cells appeared hyperplastic, and Sertoli cells, identified by Wt1, have been mislocalized and highly vacuolated (Figure 1I) [37,38]. (bet-bromodomain.com)
Leydig Cells" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings) . (umassmed.edu)
This graph shows the total number of publications written about "Leydig Cells" by people in this website by year, and whether "Leydig Cells" was a major or minor topic of these publications. (umassmed.edu)
Below are the most recent publications written about "Leydig Cells" by people in Profiles. (umassmed.edu)
Wu X, Arumugam R, Zhang N, Lee MM. Androgen profiles during pubertal Leydig cell development in mice. (umassmed.edu)
Wu X, Arumugam R, Baker SP, Lee MM. Pubertal and adult Leydig cell function in Mullerian inhibiting substance-deficient mice. (umassmed.edu)
Salva A, Hardy MP, Wu XF, Sottas CM, MacLaughlin DT, Donahoe PK, Lee MM. M?llerian-inhibiting substance inhibits rat Leydig cell regeneration after ethylene dimethanesulphonate ablation. (umassmed.edu)
Leydig cell hyperplasia may also occur with aging. (medscape.com)

Extragonadal germ cell tumors form from developing sperm or egg cells that travel from the gonads to other parts of the body. (vicc.org)
Age and gender can affect the risk of extragonadal germ cell tumors. (vicc.org)
Signs and symptoms of extragonadal germ cell tumors include breathing problems and chest pain. (vicc.org)
Imaging and blood tests are used to diagnose extragonadal germ cell tumors. (vicc.org)
Extracranial and extragonadal germ cell tumors and melanoma were both significantly decreasing. (cdc.gov)

A sample of tissue is removed and examined under a microscope to evaluate cell types, the extent of disease and other factors. (childrensoncologygroup.org)
Esters, but there will still be water hematoxylin (Sigma-Aldrich) from adipose tissue cells (adipocytes). (showyou.com)

Currently, we lack markers that we can use to pinpoint the developmental stage of human ES cell derived candidate hematopoietic stem cells (HSC), and whether they have established the correct molecular machinery required for proper function. (ca.gov)
The major shortcoming in generating functional hematopoietic stem cells (HSC) from pluripotent stem cells is the lack of adequate markers for specification and maintenance of functional human HSCs. (ca.gov)
Our goal is to develop tools that address major bottlenecks that have prevented the generation of blood forming stem cells in culture for therapeutic use. (ca.gov)
These tools will help translate the promise of stem cells to cell based therapies to treat human disease. (ca.gov)
The biological properties and clinical potential of stem cells elicit that are generated must not be unduly sensitive to small fluctu- continued scientific, commercial, and public interest. (lu.se)
To varying degrees, these fates also extend to the Such state stability is required in stem and progenitor cells to immediate progeny of stem cells, known as progenitor or support self-renewal and maintenance of the uncommitted transit-amplifying cells. (lu.se)

in each cell) may inherit variants in both copies of the SRD5A2 gene, their sexual development is not affected. (medlineplus.gov)
Moreover, we find that the distal NDRs are enriched specifically for binding motifs of the pluripotency and germ cell master regulators such as NANOG, SOX17, AP2γ and OCT4 in human FGCs, indicating the existence of a delicate regulatory balance between pluripotency-related genes and germ cell-specific genes in human FGCs, and the functional significance of these genes for germ cell development in vivo . (nature.com)
The RNA-binding protein NANOS3 poses as an interesting candidate gene for POI since members of the Nanos family have an evolutionarily conserved function in germ cell development and maintenance by repressing apoptosis. (hindawi.com)
Nanos was first identified in Drosophila , where it represses the translation of target mRNAs through binding to their 3′ UTR and has a conserved function in germ cell development across species. (hindawi.com)
In C. elegans, rpn-8 is involved in programmed cell death involved in cell development. (wormbase.org)
During normal development, SOX9 allows the prostate epithelium to outgrow into the mesenchyme and then provides basal cell support for development and maintenance of the luminal epithelium. (thermofisher.com)
Our goal is to generate a toolbox of human embryonic stem cell lines to monitor blood forming (hematopoietic) stem cell development in culture. (ca.gov)
To help overcome these bottlenecks, we will generate a suite of human embryonic stem cell reporter lines that can be used to monitor key milestones in blood stem cell development. (ca.gov)
Ovotesticular disorder of sexual development, which was previously termed "intersex," describes disorders in which there is a discrepancy between a person's phenotype, genetic material, and gonads. (medscape.com)
Such gonads are found exclusively in people with ovotesticular disorder of sexual development (OT-DSD), formerly known as true hermaphroditism. (medscape.com)
Degeneration and hyalinization of the seminiferous tubules with poor germ cell development is frequently observed. (medscape.com)
In all documented biopsied cases, there is a significant decline in germ cell development and an increase in tubular sclerosis by puberty. (medscape.com)
Internal duct development usually corresponds to the adjacent gonad. (medscape.com)
Could play a role in T-cell development, gonad and neurological function. (lu.se)

The most common tumors found in the anterior mediastinum are of thymic, lymphatic, or germ cell origin. (medscape.com)
Germ cell tumors that develop in the brain or spinal cord are also called CNS (central nervous system) germ cell tumors. (dana-farber.org)
The two main types of germ cell tumors of the brain are germinomas and non-germinomatous tumors. (dana-farber.org)
If they include aspects of both, they are called mixed germ cell tumors. (dana-farber.org)
Germ cell tumors of the brain are rare, accounting for approximately 4 percent of brain tumors in children. (dana-farber.org)
Within the Childhood Brain Tumor Center , our specialists have extensive expertise in treating all types of brain tumors, including germ cell tumors. (dana-farber.org)
These are pure germ cell tumors. (dana-farber.org)
Germ cell tumors are growths that occur in children, teens and adults. (childrensoncologygroup.org)
Germ cell tumors are rare, about 900 children and adolescents are diagnosed in the United States each year. (childrensoncologygroup.org)
If germ cells do not reach their intended destination, tumors occur wherever these cells end up. (childrensoncologygroup.org)
These may require taking samples for blood chemistry, blood cell count, genetics and certain proteins called tumor markers such as AFP and bhCG that are produced by some germ cell tumors. (childrensoncologygroup.org)
Because germ cell tumors can vary greatly, and can arise in different parts of the body, they can be difficult to stage. (childrensoncologygroup.org)
However, the Children's Oncology Group (COG) developed the following system for staging germ cell tumors. (childrensoncologygroup.org)
Childhood extracranial germ cell tumors form from germ cells in parts of the body other than the brain. (cigna.com)
This summary is about germ cell tumors that form in parts of the body that are extracranial (outside the brain). (cigna.com)
Extracranial germ cell tumors are most common in adolescents, with rates in this age group lower for females than males. (cigna.com)
For information on intracranial (inside the brain) germ cell tumors, see Childhood Central Nervous System Germ Cell Tumors Treatment. (cigna.com)
Ovarian germ cell tumors are more common in adolescent girls and young women. (cigna.com)
Most extragonadal extracranial germ cell tumors form along the midline of the body. (cigna.com)
In children younger than 11 years, extragonadal extracranial germ cell tumors usually occur at birth or in early childhood. (cigna.com)
In older children, adolescents, and young adults (11 years and older), extragonadal extracranial germ cell tumors are often in the mediastinum. (cigna.com)

Inherited genetic effects pertain to somatic and germ cell DNA transmitted through mitosis or meiosis, respectively. (cdc.gov)

They arise from germ cells , which are the cells that go on to later develop into a person's gametes (such as sperm and eggs). (livescience.com)
The type of tumor that Karanam had occurs "when a person's own germ cell multiplies abnormally and differentiates into various different, normal tissues, in an abnormal place," said Dr. Cathy Burnweit, chief of pediatric surgery at Nicklaus Children's Hospital in Miami. (livescience.com)

Analysis of embryonic XY gonads suggests that sex reversal is caused by delayed and reduced expression of the sex-determining gene SRY . (plos.org)
However, the uniform loss of germ cells in areas without sporocysts suggests that a more generalized mechanism is responsible. (int-res.com)

Understanding cell-fate decisions in stem cell populations is a major goal of modern biology. (lu.se)

Our in vivo tracking tools will be broadly relevant and not restricted to studying the in vivo biology of blood forming cells. (ca.gov)

As FSH increases during the early portion of the follicular phase, it meshes with granulosa cells to stimulate the aromatization of androgens into estradiol. (medscape.com)

If the neurons are radially symmetrical, each cell has a three-letter name followed by L (left), R (right), D (dorsal), or V (ventral). (wormatlas.org)
Longitudinal nerve tracts travel along the body at ventral, subventral, lateral, subdorsal, and dorsal positions and connect cell bodies to major neuropils. (wormatlas.org)

McGrew believes the likely solution is to inject genetically edited cells into the gonads of a developing pigeon chick. (technologyreview.com)

These gonads hang in a happy pair inside the scrotum, just below the penis. (iheartguts.com)

During migration in embryos, cells must alter their overall adhesiveness to the substrate to allow locomotion. (silverchair.com)

FSH is secreted into the circulation and communicates with the granulosa cells surrounding the developing oocytes. (medscape.com)
The LH surge promotes maturation of the dominant oocyte, the release of the oocyte and then the luteinization of the granulosa cells and the surrounding theca cells of the dominant follicle resulting in progesterone production. (medscape.com)
HN - 2008 BX - Von Ebner's Glands MH - Cumulus Cells UI - D054885 MN - A05.360.319.114.630.535.200.500 MN - A06.407.312.497.535.300.500 MN - A11.436.300.500 MS - The granulosa cells of the cumulus oophorus which surround the OVUM in the GRAAFIAN FOLLICLE. (bvsalud.org)
HN - 2008 BX - Granulosa Cells, Cumulus MH - Coronary Sinus UI - D054326 MN - A07.231.908.194.500 MS - A short vein that collects about two thirds of the venous blood from the MYOCARDIUM and drains into the RIGHT ATRIUM. (bvsalud.org)

which means both copies of the SRD5A2 gene in each cell must have a variant to cause the disorder. (medlineplus.gov)
The problem is that while it is easy to gene-edit bird cells in the lab, it's hard to turn carefully edited cells back into a bird. (technologyreview.com)
Similarly, GATA-1 has been shown to induce lineage switching expression values even if, for simplicity, we assume only ``on'' of committed cells in hematopoiesis, first in cell lines (Kulessa and ``off'' states for each gene. (lu.se)

This paper gives an Islamic perspective on some of these advances, including abortion, in vitro fertilization, genetic engineering, cloning and stem cell research. (who.int)

Drosophila CIAPIN1 homologue is required for follicle cell proliferation and survival. (nih.gov)

check the tag ADOLESCENCE HN - 2008 BX - Nutrition in Adolescence FX - Adolescent Nutrition Physiology MH - Peritoneal Stomata UI - D054048 MN - A01.047.025.600.700 MN - A10.810 MS - Natural openings in the subdiaphragmatic lymphatic plexus in the PERITONEUM, delimited by adjacent mesothelial cells. (bvsalud.org)

see Muscle System - GLR Cells ), which are associated only with the somatic nervous system. (wormatlas.org)

Anatomy16

Organisms5

Diseases5

Chemicals and Drugs14

Analytical, Diagnostic and Therapeutic Techniques and Equipment2

Phenomena and Processes11

Disciplines and Occupations1

Information Science2

Testis8

Ovaries8

Testes1

Ovary2

Differentiation11

Fetal4

Testicles2

Organs10

Embryo3

Hypothalamus1

Luteinizing hormone3

Hormones6

Cause of germ cell t2

Histology2

Gonadal4

Testicular4

Reproductive cells3

PGCs6

Sperm and egg1

E13.51

Somatic cells2

Male4

Carcinoma2

Germ cell3

Ovotestis1

Malignant12

Regulation3

Teratomas8

Primordial germ2

Leydig8

Extragonadal germ cell t5

Tissue2

Stem Cells6

Development14

Tumors21

Meiosis1

Person's2

Suggests2

Populations1

Biology1

Stimulate1

Dorsal2

Genetically1

Scrotum1

Migration1

Granulosa cells4

Gene3

Genetic1

Proliferation1

Adjacent1

Nervous system1