Hepatitis B envelope antigenAspartate aminotransferaseResiduesAntigenVitroEpidermalSerumVaccines deliver genetic materialEpitheliaMembraneGeneTransglutaminaseRibosylation factorAntibody- secrEnzymeCellularEnsemblDistinguishSpikeImmunityGolgiCYTOPLASMParticlesSpeciesFormationNucleusStrainsAbnormalNEUTROPHILSOrganizationVaccineAdaptiveDifferentiationMoleculesGenesHumanTOTALTissueRegulationBloodCopperActivitySpecific
Hepatitis B envelope antigen1
- 4. Negative hepatitis B envelope antigen predicts intrahepatic recurrence in hepatitis B virus-related hepatocellular carcinoma after ablation therapy. (nih.gov)
Aspartate aminotransferase2
- 2. Diagnostic value of gamma-glutamyltransferase/aspartate aminotransferase ratio, protein induced by vitamin K absence or antagonist II, and alpha-fetoprotein in hepatitis B virus-related hepatocellular carcinoma. (nih.gov)
- The aim of this cross-sectional study was to present nationally representative findings on the co-occurrence of obesity and specific patterns of alcohol use associated with elevated serum alanine aminotransferase (ALT), aspartate aminotransferase (AST), and gamma-glutamyltransferase (GGT) among adults in the United States. (cdc.gov)
Residues3
- The specific cross linkages formed by keratinocyte transglutaminase are between n^ε-(γ-glutamyl)lysine residues which develop into isopeptide protein-protein linkages that adds to the stabilization of the cornified cell envelope. (wikipedia.org)
- This post-translational modification on lysine residues of proteins plays a crucial role in a number of cellular processes such as nuclear transport, DNA replication and repair, mitosis and signal transduction. (nih.gov)
- Enzyme-linked immunosorbent assays utilizing virus-like particles containing mutations of conserved residues on envelope protein can distinguish three flavivirus infections. (elisareagents.com)
Antigen1
- The B lymphocytes (B cells) are antibody-producing cells that are essential for acquired, antigen-specific immune responses. (ultalabtests.com)
Vitro2
- "In this study we present evidence that COVID-19 mRNA vaccine BNT162b2 is able to enter the human liver cell line Huh7 in vitro, " the researchers wrote in the study, published in Current Issues of Molecular Biology . (covfefebakery.org)
- This is the first time that researchers have shown in vitro or inside a petri dish how an mRNA vaccine is converted into DNA on a human liver cell line, and is what health experts and fact-checkers said for over a year couldn't occur. (covfefebakery.org)
Epidermal2
- Keratinocyte transglutaminase enzymes serve to specifically catalyze the development of the cornified cell envelope, a defining characteristic of epidermal keratinocytes that have undergone the termination of differentiation. (wikipedia.org)
- In the epidermis, transglutaminase 5 is involved in the formation of a structure called the cornified cell envelope, which surrounds epidermal cells and helps the skin form a protective barrier between the body and its environment. (medlineplus.gov)
Serum5
- 5. Serum alpha-fetoprotein measurement in predicting clinical outcome related to autologous cytokine-induced killer cells in patients with hepatocellular carcinoma undergone minimally invasive therapy. (nih.gov)
- 7. High levels of serum Mac-2-binding protein glycosylation isomer (M2BPGi) predict the development of hepatocellular carcinoma in hepatitis B patients treated with nucleot(s)ide analogues. (nih.gov)
- In 1932, Paul and Bunnell discovered that serum from symptomatic patients had antibodies that agglutinate the red blood cells (RBCs) of unrelated species, the "heterophile antibodies. (medscape.com)
- Description: A sandwich ELISA kit for detection of Loricrin from Human in samples from blood, serum, plasma, cell culture fluid and other biological fluids. (jsce-ip.com)
- Description: Quantitative sandwich ELISA for measuring Human Loricrin (LOR) in samples from cell culture supernatants, serum, whole blood, plasma and other biological fluids. (jsce-ip.com)
Vaccines deliver genetic material2
- These vaccines deliver genetic material that instructs cells to begin making spike proteins found on the surface of SARS-CoV-2 that causes COVID-19 to produce an immune response. (covfefebakery.org)
- Viral vector COVID-19 vaccines deliver genetic material to the cell nucleus to allow our cells to build protection against COVID-19. (masksickness.ca)
Epithelia3
- In terminally differentiated stratified squamous epithelia, the cornified cell envelope protein linkages allow for a structurally fortified, yet flexible (15 nm thick) layer to the place of the cell membrane, acting as a highly insoluble barrier. (wikipedia.org)
- The cell envelope (CE) is a vital structure for barrier function in terminally differentiated dead stratified squamous epithelia. (nih.gov)
- It is assembled by transglutaminase (TGase) cross-linking of several proteins, including SPR3 in certain specialized epithelia normally subjected to mechanical trauma. (nih.gov)
Membrane6
- The expression of the enzyme is most highly exhibited along the biological membrane of these fully formed epithelial cells, preventing the cell from undergoing chemical and or physical damages. (wikipedia.org)
- Membrane-bound electron-dense organelles, 50-200 nm in size found in Vesicles neurons and endocrine cells. (nih.gov)
- In a different study, the spike proteins made in the body after receiving a Pfizer COVID-19 shot have been found on tiny membrane vesicles called exosomes -that mediate cell-to-cell communication by transferring genetic materials to other cells- for at least four months after the second vaccine dose. (covfefebakery.org)
- HlyD membrane-fusion protein of T1SS, Barrel-sandwich domain of CusB or HlyD membrane-fusion [Interproscan]. (ntu.edu.sg)
- protein_coding" "AAC73829","ybgE","Escherichia coli","putative inner membrane protein in cydABX-ybgE operon [Ensembl]. (ntu.edu.sg)
- HN - 2022 BX - Adolescent Motherhood BX - Teen Mothers BX - Teenage Mothers FX - Pregnancy in Adolescence MH - ADP-Ribosylation Factor 6 UI - D000089982 MN - D8.811.277.40.330.300.400.100.50 MN - D12.776.157.325.515.100.550 MN - D12.776.476.338.400.100.50 MS - A member of GTP-binding protein of the large ras superfamily involved in regulation of membrane trafficking by modulating ENDOCYTOSIS and ACTIN CYTOSKELETON remodeling. (nih.gov)
Gene9
- Protein-glutamine gamma-glutamyltransferase K is a transglutaminase enzyme that in humans is encoded by the TGM1 gene. (wikipedia.org)
- This lack of protein stems from a common mutation of the TGK gene, which exists in two possible variants, found at the TGM1 locus on the 14q11 chromosome, as exhibited amongst all the subjects of the study. (wikipedia.org)
- This and other T GM5 gene variants reduce the activity of transglutaminase 5 or prevent cells from making any of this enzyme. (medlineplus.gov)
- Total DNA and RNA were extract- the nonstructural protein (NS) 2a and USUV strains, a spillover infection ed from tissue samples (brain, liver, the other (L1549F) in the NS3 gene-- from birds or another, yet unrecog- lung, and heart) and subjected to reverse which were detected only in the bird- nized, host cannot be ruled out. (cdc.gov)
- Use of a cytochrome (A1841V and K1870M) in the NS3 nervous system in bats, as opposed b-specific PCR and direct sequencing protein gene of the BAT1USUTU-BNI to the pantropism observed in birds of the PCR amplicons genetically iden- strain were also identified. (cdc.gov)
- The researchers found that when the mRNA vaccine enters the human liver cells, it triggers the cell's DNA , which is inside the nucleus, to increase the production of the LINE-1 gene expression to make mRNA . (covfefebakery.org)
- A gene known as FGFR2 is responsible for the formation of bone cells and the subsequent development of bone structure. (factdr.com)
- To identify which bacterial genes are involved in gastric colonization, gene expression profiles of Helicobacter bacteria attached to gastric epithelial cells need to be compared with those of unbound bacteria. (biomedcentral.com)
- Probe Set ID Ref Seq Protein ID Signal Strength Name Gene Symbol Species Function Swiss-Prot ID Amino Acid Sequence 1367452_at NP_598278 16.8 small ubiquitin-related modifier 2 precursor Sumo2 Rattus norvegicus " Ubiquitin-like protein that can be covalently attached to proteins as a monomer or as a lysine-linked polymer. (nih.gov)
Transglutaminase3
- Specifically, transglutaminase 5 forms strong bonds, called cross-links, between the structural proteins that make up the cornified cell envelope. (medlineplus.gov)
- Most of the variants that cause the condition change single protein building blocks (amino acids) in transglutaminase 5. (medlineplus.gov)
- A shortage of transglutaminase 5 function impairs protein cross-linking, which weakens the cornified cell envelope and allows the outermost cells of the epidermis to separate easily from the underlying skin and peel off. (medlineplus.gov)
Ribosylation factor1
- HN - 2022 BX - ADP Ribosylation Factor 6 BX - ARF6 Protein MH - Aerosolized Particles and Droplets UI - D000088342 MN - D20.65 MS - A suspension of tiny particles or liquid droplets ( (nih.gov)
Antibody- secr1
- A subset of activated B cells generated in response to primary immune challenge or immunization which are capable of giving rise to antibody- secreting cells upon re-challenge (see IMMUNOLOGIC MEMORY). (nih.gov)
Enzyme3
- Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Human Loricrin (LOR) in Tissue homogenates, cell lysates and other biological fluids. (jsce-ip.com)
- Description: Enzyme-linked immunosorbent assay based on the Double-antibody Sandwich method for detection of Human Loricrin (LOR) in samples from Tissue homogenates, cell lysates and other biological fluids with no significant corss-reactivity with analogues from other species. (jsce-ip.com)
- Single Molecule Protein Detection with Attomolar Sensitivity Utilizing Droplet Digital Enzyme-Linked Immunosorbent Assay Many proteins are current at low concentrations in organic samples, and subsequently, methods for ultrasensitive protein detection are mandatory. (elisareagents.com)
Cellular1
- Condensates separation from the surrounding CYTOPLASM or nucleoplasm or by the concentration of proteins and nucleic acids into droplets as they aggregate on static cellular structures such as CELL MEMBRANES. (nih.gov)
Ensembl3
- protein_coding" "AAC73262","fhuC","Escherichia coli","iron(3+)-hydroxamate import ABC transporter ATPase [Ensembl]. (ntu.edu.sg)
- protein_coding" "AAC73263","fhuD","Escherichia coli","iron(3+)-hydroxamate import ABC transporter periplasmic binding protein [Ensembl]. (ntu.edu.sg)
- protein_coding" "AAC74417","ogt","Escherichia coli","O-6-alkylguanine-DNA:cysteine-protein methyltransferase [Ensembl]. (ntu.edu.sg)
Distinguish1
- The second type are T lymphocytes (T cells) some T cells help the body distinguish between "self" and "non-self" antigens while others initiate and control the extent of an immune response, boosting it as needed and then slowing it as the condition resolves. (ultalabtests.com)
Spike4
- A segment of the protein called the open reading frame-1, or ORF-1, then goes back into the nucleus, where it attaches to the vaccine's mRNA and reverse transcribes into spike DNA . (covfefebakery.org)
- Spike proteins may circulate in the body after an infection or injection with a COVID-19 vaccine. (covfefebakery.org)
- It was assumed that the vaccine's spike protein would remain mostly at the injection site and last up to several weeks like other proteins produced in the body. (covfefebakery.org)
- Its vector encodes the SARS-CoV-2 Spike protein. (nih.gov)
Immunity1
- Building immunologic memory cells is a basis of how a vaccine affords immunity to a specific pathogen. (nih.gov)
Golgi1
- Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins. (nih.gov)
CYTOPLASM2
- The mRNA then leaves the nucleus and enters the cell's cytoplasm, where it translates into LINE-1 protein. (covfefebakery.org)
- The ternary complex containing UFD1L, VCP and NPLOC4 binds ubiquitinated proteins and is necessary for the export of misfolded proteins from the ER to the cytoplasm, where they are degraded by the proteasome. (nih.gov)
Particles1
- In 1964, Epstein described the first human tumor virus when he found virus particles in a Burkitt lymphoma cell line. (medscape.com)
Species3
- The largest differences can be found between the protein content of individual species. (encyclopedia.pub)
- Therefore, colostrum from each of the mentioned species could be used as a raw material supplying proteins, especially those with biologically active properties. (encyclopedia.pub)
- To gain more insight into the interactions of both zoonotic Helicobacter species with human gastric epithelial cells, we investigated bacterial genes that are differentially expressed in a H. suis and H. heilmannii strain after adhesion to the human gastric epithelial cell line MKN7. (biomedcentral.com)
Formation1
- The NPLOC4-UFD1L-VCP complex regulates spindle disassembly at the end of mitosis and is necessary for the formation of a closed nuclear envelope. (nih.gov)
Nucleus1
- The genetic material delivered by mRNA vaccines never enters the nucleus of your cells, which is where your DNA is kept. (masksickness.ca)
Strains3
- USUV the bat USUV strains in cell culture used more available sequences from circulates between ornithophilic were not successful, probably because databases yielded the same topology mosquito vectors (mainly Culex spp. (cdc.gov)
- The differences between the strains are due to the altered sequence of viral genes expressed during latent infection, which differ in their ability to transform B cells. (medscape.com)
- Differentially expressed genes of the H. suis and H. heilmannii strains belonged to multiple functional classes, indicating that adhesion of both strains to human gastric epithelial cells evokes pleiotropic adaptive responses. (biomedcentral.com)
Abnormal2
- Such mutations were of the compound heterozygous or homozygous variety, which leads to the expression of lamellar ichthyosis as a result of abnormal cross-linkaging of the cornified cell envelope. (wikipedia.org)
- The third type are natural killer cells (NK cells) that directly attack and kill abnormal cells such as cancer cells or those infected with a virus. (ultalabtests.com)
NEUTROPHILS3
- Immature forms of neutrophils are called neutrophilic band cells. (ultalabtests.com)
- Neutrophils are a type of white blood cell that is responsible for much of the body's protection against infection. (ultalabtests.com)
- Large numbers of immature forms of neutrophils, called neutrophilic band cells, are produced by the bone marrow when the demand is high. (ultalabtests.com)
Organization1
- Extracellular and organization of tissue-specific proteins and polysaccharides. (nih.gov)
Vaccine3
- The messenger RNA ( mRNA ) from Pfizer's COVID-19 vaccine is able to enter human liver cells and is converted into DNA , according to Swedish researchers at Lund University. (covfefebakery.org)
- "Our COVID-19 vaccine does not alter the DNA sequence of a human cell," a Pfizer spokesperson told The Epoch Times in an email. (covfefebakery.org)
- As The Epoch Times and other media outlets reported yesterday, a shocking new study conducted at Lund University in Sweden has confirmed that mRNA nanoparticles from Pfizer's COVID-19 vaccine enter human cells and are reverse-transcripted into DNA , achieving a permanent alteration of the person's genetic code. (masksickness.ca)
Adaptive1
- Immunologic memory cells typically include B-Lymphocytes T-Lymphocytes and sometimes adaptive NK cells. (nih.gov)
Differentiation1
- The aim of this dataset was to study in detail the transcription kinetics initiated by cytokine IL-4 in early differentiation of Th2 cells. (gsea-msigdb.org)
Molecules1
- The main source of active molecules of milk consists of casein and whey proteins, which demonstrate a range of antimicrobial, antioxidant, and immunomodulatory properties, among others [ 14 ] . (encyclopedia.pub)
Genes3
- A lesser amount of enzymatic activity, of the TGK genes (5-10%), lies within the cytoplasmic fraction of such cells, allowing for finalization of the cross-linkaging necessary for the full functionality of the cornified cell envelope. (wikipedia.org)
- Genes up-regulated in comparison of CD4 [GeneID=920] T cells treated with IL4 [GeneID=3565] and anti-IL12 at 1 h versus the untreated cells at 1 h. (gsea-msigdb.org)
- To gain more insights into the pathogenesis of animal-associated Helicobacter infections in humans, we compared the expression of H. suis and H. heilmannii genes upon binding to human gastric epithelial MKN7 cells to unbound H. suis and H. heilmannii . (biomedcentral.com)
Human1
- In human adults, enfuvirtide has a volume of distribution of 5.48 L, is highly bound to plasma protein (92%), has a plasma elimination half-life of 3.8 hours, and is catabolized by peptidases and proteinases in various tissues. (nih.gov)
TOTAL3
- Basophils normally constitute 1% or less of the total white blood cell count but may increase or decrease in certain diseases and are thought to be involved in allergic reactions. (ultalabtests.com)
- Sheep milk and sheep colostrum is distinguished by the highest total protein and fat content, being almost one and a half that of cow or goat milk and colostrum ( Table 1 ). (encyclopedia.pub)
- No se detectó HBsAg, pero se detectó el reactivo anti-HBc total aislado en el 1,6% de los individuos. (bvsalud.org)
Tissue1
- Description: tissue homogenates, cell lysates and other biological fluids. (jsce-ip.com)
Regulation1
- Ribonucleoprotein regulation in GERM CELLS. (nih.gov)
Blood5
- In 1920, Sprunt and associates applied the name infectious mononucleosis to cases of spontaneously resolving acute leukemia associated with blast-like cells in the blood. (medscape.com)
- These aggressive tumors - later named after him as Burkitt lymphoma - were caused by white blood cells multiplying out of control. (medscape.com)
- Blasts are immature forms of white blood cells. (ultalabtests.com)
- Lymphocytes are white blood cells that exist in both the blood and the lymphatic system. (ultalabtests.com)
- Nucleated Red Blood Cells (nRBC) ) the presence of NRBCs in the adult blood is usually associated with malignant neoplasms, bone marrow diseases, and other serious disorders. (ultalabtests.com)
Copper1
- Copper binding periplasmic protein CusF [Interproscan]. (ntu.edu.sg)
Activity2
Specific1
- It contains a colloidal dispersion of specific proteins as micelles, fats organized in emulsified globules, as well as lactose, various minerals, and vitamins in solution [ 3 ] . (encyclopedia.pub)