• role
  • To evaluate the role of AIF in BAX-dependent (DNA damage induced) and BAX-independent (excitotoxic) neuronal death, we used Harlequin ( Hq ) mice, which are hypomorphic for AIF. (jneurosci.org)
  • Presently, the role of AIF as a death executor or as an oxidative stress scavenger is controversial. (jneurosci.org)
  • studies
  • Then, we carried out dose-response studies by transfecting the rapamycin-exposed cell lines with various concentrations of LC3 II short hairpin RNA (shRNA) plasmid and treating them with several doses of GST alone and in combination. (aacrjournals.org)