• cyclin
  • Cell cycle progression is regulated by the cyclic rise and fall of kinase expression, and their interaction with, and action on, their cyclin targets. (qiagen.com)
  • Key genes that regulate cell cycle progression and checkpoints encode cullins, cyclins, and cyclin-dependent kinases and their inhibitors. (qiagen.com)
  • Cyclin dependent kinases: Cdks) promote cell division by phosphorylating and reversibly inactivating Rb by a hierarchical series of phosphorylation events and sequential conformational changes. (wustl.edu)
  • normally
  • At sea level normally menstruating women show increased ventilation (V̇ e ) and hemodynamic changes due to increased progesterone (P) and estrogen (E2) levels during the mid-luteal (L) compared to the mid-follicular (F) phase of the ovarian cycle. (biologists.org)
  • Methods
  • Practical and comprehensive, Cell Cycle Synchronization: Methods and Protocols, Second Edition is a valuable resource for PhD students and postdoctoral fellows, and researchers interested in general science, pharmacy, medicine and public health, computer science, and life sciences. (springer.com)
  • tissue
  • PharmaMar S.A.U., Madrid, Spain) is a promising anticancer agent that has demonstrated clinical activity in many drug-resistant cancer cell lines, and has been approved by the US Food and Drug Administration for advanced soft tissue sarcoma. (frontiersin.org)
  • interaction
  • Phosphorylation by p38, but not Cdks, triggers an interaction between Rb and the human homologue of murine double minute 2: Hdm2), leading to degradation of Rb, release of E2F1 and cell death. (wustl.edu)
  • Measures
  • Using a repeated-measures design on a large study sample, our purpose was to determine whether ovarian cycle-phase affects maximal exercise performance (V̇ O 2 max ) in women who had lived at an altitude of 3600 m since birth or early childhood. (biologists.org)
  • provides
  • This second edition volume provides detailed protocols on the theoretical background of cell cycle synchronization procedures and instructions on how to implement these techniques. (springer.com)