• Consequentially, the decrease in pressure results in overall peripheral edema and ascites. (wikipedia.org)
  • The summation of these effects ultimately leads to peripheral edema and ascites. (wikipedia.org)
  • All in all, the left side failure of the heart will lead to pulmonary edema whereas right side failure will lead to peripheral edema and ascites. (wikipedia.org)
  • This is called peripheral edema . (healthline.com)
  • Most of the time, peripheral edema develops because you're retaining fluid. (healthline.com)
  • Sometimes peripheral edema is more severe, however. (healthline.com)
  • When other symptoms occur with peripheral edema, you might have a serious medical condition that requires urgent medical attention. (healthline.com)
  • Peripheral edema that's moderate to severe, getting worse, or doesn't improve with rest is more serious. (healthline.com)
  • What are the symptoms of peripheral edema? (healthline.com)
  • What causes peripheral edema? (healthline.com)
  • Most often, peripheral edema is the result of fluid retention rather than an underlying condition. (healthline.com)
  • This leads to peripheral edema, which may cause more noticeable sock marks the next evening. (healthline.com)
  • This slows the movement of blood from her legs up to her heart, which can lead to peripheral edema. (healthline.com)
  • Most pregnant women get peripheral edema, but it can also be a sign of a serious condition called preeclampsia . (healthline.com)
  • Peripheral edema often occurs in hot weather. (healthline.com)
  • In clinical examination dog was suffered from ascites, inspiration dyspnea, weakness, mild peripheral edema on limbs, unobvious lung and heart sounds, mild serous nasal discharge, anemia and cachexia. (vin.com)
  • A 68-year old male with a history of inferior myocardial infarction with right ventricle (RV) involvement was thrice-hospitalized due to marked ascites and peripheral oedema. (biomedcentral.com)
  • Vital signs were stable and physical examination identified marked ascites and peripheral oedema. (biomedcentral.com)
  • [ 2 ] It has become clear that AILD is a clonal T-cell disorder involving deregulation of B-cells and endothelial cells against a background involving a unique malignant microenvironment. (medscape.com)
  • We depicted a single-cell landscape of OC ecosystem with five tumour-relevant sites: peripheral blood (PB), pelvic lymph node (PLN), primary tumour (Pri.OT), omentum metastasis (Met.Ome), and malignant ascites. (mendeley.com)
  • Fresh samples including primary ovarian tumour, omentum metastatic tumour, pelvic lymph node, malignant ascites and peripheral blood were obtained from these patients during surgery. (mendeley.com)
  • Paracentesis unveiled a serum-ascites albumin gradient of 1.3 g/dL with no malignant cells, thus suggestive of portal hypertension. (biomedcentral.com)
  • Disseminated encephalitis occurs after age Physical therapy can cause peripheral neuropathies, radiation chronic noncancer pain is difficult to ing systems, or air in the treatment of malignant granulomatous peritonitis ascites are bloody. (familyfm.org)
  • 2021 BD launched the first at-home system in the U.S. indicated for malignant and non-malignant ascites drainage. (bd.com)
  • cialis Lichenoid drug eruptions are generally normal unless there is are flushed free from partial ureterectomy the management of renal cell carcinoma of Namic, and may show brospinal fluid. (familyfm.org)
  • BCC), among hospitalized patients at hospital A. Most sequences of B. stabilis for all eight clinical (seven from blood patients had undergone ultrasound-guided procedures during and one from ascites fluid) and three product isolates collected their admission. (cdc.gov)
  • There were significantly higher levels of IL-6 in ascites fluid compared to blood samples in all patients. (frontiersin.org)
  • symptomatic measures for ascites include the appointment of diuretics, puncture removal of fluid from the abdominal cavity. (medic-journal.com)
  • The accumulation of peritoneal fluid in ascites is accompanied by an increase in intra-abdominal pressure, pushing the dome of the diaphragm into the thoracic cavity. (medic-journal.com)
  • Significant loss of liver function may be manifested by hemorrhage from varices or portal hypertensive gastropathy, ascites (accumulation of fluid in the abdominal cavity), hydrothorax (ascitic fluid in the chest cavity), or encephalopathy. (ultimatedisabilityguide.com)
  • Thus, increased portal pressure causes increased filtration of vascular fluid with the formation of ascites and the development of collaterals through alternating veins leading to esophageal, gastric, and rectal varices. (fortunejournals.com)
  • Sampling from ascites fluid showed it is a modified transudate. (vin.com)
  • Differentiating between low-grade lymphoma and reactive lymphocytes is often difficult by morphology alone as reactive lymphoid cells may acquire activation morphology from being exposed to different cytokines within the body fluid. (cytojournal.com)
  • In large cell lymphoma and leukemia cells involvement of body fluid this concept becomes less challenging. (cytojournal.com)
  • BACKGROUND: The aim of this study was to assess the role of transabdominal ultrasonography in characterizing and determining the etiology of ascites in comparison with laboratory ascitic fluid analysis and other methods used to establish the final diagnosis. (bvsalud.org)
  • An abdominal ultrasonogram showed hepatomegaly, splenomegaly and ascites. (fortunejournals.com)
  • In 1899, Chiari described an "obliterating endophlebitis of the hepatic veins" and its association with hepatomegaly, ascites and abdominal pain. (medscape.com)
  • Benign cystic mesothelioma: A rare cause of ascites in a case with familial Mediterranean fever. (florence.com.tr)
  • The cause of ascites was established in 59 cases using a combination of clinical, pathological, imaging evidences and tumor markers. (bvsalud.org)
  • Frequent causes of ascites are diseases occurring with portal hypertension - an increase in pressure in the portal system of the liver (portal vein and its tributaries). (medic-journal.com)
  • Urine examination revealed nephrotic-range proteinuria and 30-35 (mostly dysmorphic) red blood cells/high power field magnification. (ijpmonline.org)
  • Dunleavy et al noted that overexpression of the chemokine CXCL13 and vascular endothelial growth factor-A in angioimmunoblastic T cell lymphoma suggests that it may be derived from follicular helper T cells. (medscape.com)
  • We propose that in settings of decreased Akt activity, induction of Ang-2 is an adaptive mechanism that serves to promote endothelial cell survival and/or vascular maturation via Tie2/Akt signaling. (careersfromscience.org)
  • These are arranged in plates one cell thick, bordering the vascular sinusoids through which flows hepatic arterial and portal venous blood. (clinicalgate.com)
  • The blood flowing through the vascular sinusoids is separated from the liver cells by a thin fenestrated (porous) barrier of cells ( endothelial cells and phagocytic Kupffer cells ) and the space of Disse . (clinicalgate.com)
  • changes in peripheral vascular resistance and wall tension. (florence.com.tr)
  • Systemic scleroderma is a rare disease in which visceral manifestations occur, particularly peripheral vascular, digestive, cardiopulmonary and renal. (scirp.org)
  • To address this question, peripheral blood samples from 12 AGC patients with organ-specific metastasis, including distant lymphatic, hepatic and peritoneal metastasis, were collected to purify exosomes and to detect exosome proteins by Nano-HPLC-MS/MS. Gastric cancer cell lines were used for in vitro experiments. (bvsalud.org)
  • Replication of examinations such as patient's mental state, the virus in lymphoid cells may cause extra- build, pulse rate, respiratory rate, body tem- hepatic manifestations. (who.int)
  • Paracentesis is essential in determining whether ascites is caused by portal hypertension or by another process. (medscape.com)
  • ZYNLONTA is a CD19-directed antibody and alkylating agent conjugate indicated for the treatment of adult patients with relapsed or refractory large B-cell lymphoma after two or more lines of systemic therapy, including diffuse large B-cell lymphoma (DLBCL) not otherwise specified, DLBCL arising from low-grade lymphoma, and high-grade B-cell lymphoma. (nih.gov)
  • Here we investigated whether levels of IL-6 and IL-8 putatively produced by myeloid cells in ascites are associated with systemic inflammation and whether inflammation depends on the presence of specific bacterial DNA. (frontiersin.org)
  • Interestingly, IL-6 levels in blood correlated tightly with disease severity and surrogates of systemic inflammation, while IL-6 levels in ascites did not. (frontiersin.org)
  • We identified differences in microbial composition and diversity between ascites and blood, but no tight relationship with surrogates of systemic inflammation could be observed. (frontiersin.org)
  • In decompensated cirrhosis, markers of systemic inflammation and microbiota composition seem to be dysregulated in ascites and blood. (frontiersin.org)
  • While a relationship between systemic inflammation and microbiota composition seems to exist in blood, this is not the case for ascites in our hands. (frontiersin.org)
  • 4. Acute infection with evidence of systemic involvement (e.g., clinically suspected infection with fever or elevated serum white blood cell count). (who.int)
  • In the event of a pregnancy where the fetus has the Rh-D blood antigen and the mother does not, the mother's immune system will respond to the red blood cells as foreign and create antibodies against the Rh-D antigen on the fetal blood cells. (wikipedia.org)
  • Rh disease develops in the event of a second pregnancy where the mother's immune system launches an attack, via IgG, against the infant's Rh-D positive blood cells. (wikipedia.org)
  • The immune response results in hemolysis of fetal red blood cells causing severe anemia. (wikipedia.org)
  • Monitor blood cell counts. (nih.gov)
  • Clinical manifestations of PNH occur when a HSC clone carrying somatic PIGA mutations acquires a growth advantage and differentiates, generating mature blood cells that are deficient of GPI-anchored proteins. (medscape.com)
  • The name of the disorder is a descriptive term for the clinical consequence of red blood cell (RBC) breakdown with release of hemoglobin into the urine, which manifests most prominently as dark-colored urine in the morning (see image below). (medscape.com)
  • The principal studies used to establish the diagnosis of PNH are flow cytometry of peripheral blood and bone marrow analysis. (medscape.com)
  • Peripheral blood sample and ascites sample from one patient were further analyzed by single-cell RNA sequencing. (bvsalud.org)
  • Although the different types of large babesia differ in virulence, geographical location, and tick vector, they are identical in appearance as bi-lobed, pear shaped organisms in the red blood cell. (dvm360.com)
  • The LSM 12.125 antibody reacts with the canine form of the 56 kDa transmembrane glycoprotein, CD4, present on the T-helper/inducer subset of normal canine donor peripheral blood lymphocytes. (bdbiosciences.com)
  • Objective To test the hypothesis that red blood cell (RBC) transfusions increase the risk of necrotizing enterocolitis (NEC) in premature infants, we investigated whether the risk of "transfusion-associated" NEC is higher in infants with lower hematocrits and advanced postnatal age. (anti-cancers.com)
  • Peripheral Blood Mononuclear Cells (PBMC) are labeled with BD IMag™ Anti-Human CD8 Magnetic Particles - DM according to the Magnetic Labeling Protocol. (bdbiosciences.com)
  • We enrolled 33 patients with decompensated liver cirrhosis from whom we collected paired samples of blood and ascites. (frontiersin.org)
  • In a subset of 10 representative patients, bacterial DNA was extracted from ascites and whole blood, followed by 16S rRNA gene amplicon sequencing. (frontiersin.org)
  • Bacterial richness was also significantly higher in ascites compared to the corresponding patient blood. (frontiersin.org)
  • I. The blood glucose increases to m/s in large studies demonstrated that the physician and the ability of distant capillaries to nerve cells and some of the last gasp, minutes of crushing substernal chest pressure and thus cause leakage, which should be done at the time the softened structure exists. (elastizell.com)
  • Hence, analysis of readily accessible peripheral blood is critical for developing biomarkers with clinical utility. (biomedcentral.com)
  • Primary human T cells were separated from human peripheral blood. (bmj.com)
  • In the center of the glomerulus are the mesangial cells which help in regulating blood flow the glomeruli. (armandoh.org)
  • Another theory sug- perature, blood pressure, and noting signs gests that circulating immune complexes of liver cell failure such as pallor, jaundice, composed of HCV antigens and antibodies palmar erythema, fetor hepaticus and flap- deposit in tissues and initiate an inflamma- ping tremor. (who.int)
  • Ascites of tuberculous etiology are also characterized by weight loss, fever, and general intoxication phenomena. (medic-journal.com)
  • Overview of Plasma Cell Disorders Plasma cell disorders are a diverse group of disorders of unknown etiology characterized by Disproportionate proliferation of a single clone of B cells Presence of a structurally and electrophoretically. (msdmanuals.com)
  • RÉSUMÉ Nous avons passé en revue les manifestations dermatologiques liées à l'infection chronique par le virus de l'hépatite C (VHC) et leur rapport avec l'état hépatique. (who.int)
  • γδ T-cell cytotoxicity and granzyme A/B production were enhanced after pretreatment of tumor cells with TLR3 [poly(I:C)] or TLR7 ligand (imiquimod). (aacrjournals.org)
  • Poly(I:C) treatment of pancreatic adenocarcinomas followed by coculture with γδ T cells resulted in an upregulation of CD54 on the tumor cells. (aacrjournals.org)
  • Moreover, treatment with imiquimod downregulated MHC class I molecules on tumor cells possibly resulting in a reduced binding affinity for inhibitory receptor NKG2A expressed on γδ T cells. (aacrjournals.org)
  • Tumor-specific neoantigens, which are expressed on tumor cells, can induce an effective antitumor cytotoxic T-cell response and mediate tumor regression. (wjgnet.com)
  • Circulating tumor cells also demonstrate prognostic value as liquid biopsies in certain tumor types such as breast and prostate, with measurement of nuclear proteins such as prostate cancer androgen receptor splice variant-7, providing additional supportive information for prognosis and therapy selection [ 6 ]. (biomedcentral.com)
  • Conclusions In general, SHP099 can not only boost the tumor-cytotoxicity effect and overcome the drug resistance of AZD4547, but also activate cytotoxic T lymphocytes to kill tumor cells in FGFR2-alterated gastric cancers. (bmj.com)
  • Ascites is a secondary condition characterized by the accumulation of exudate or transudate in the free abdominal cavity. (medic-journal.com)
  • Excluding mixed and indeterminate cases, ultrasound characterized ascites correctly as exudate and transudate in 95% cases. (bvsalud.org)
  • CONCLUSION: Ultrasound has significant accuracy to distinguish transudate and exudate ascites and in suggesting the underlying cause. (bvsalud.org)
  • This is because many patients with SBP show negative bacterial cultivation from ascites, while in many other patients, viable bacteria can be cultivated in the absence of peritonitis, so-called bacterascites ( 3 ). (frontiersin.org)
  • Ascites in tuberculous peritonitis is caused by secondary infection of the peritoneum due to genital tuberculosis or intestinal tuberculosis. (medic-journal.com)
  • For stromal cells in ascites, DES+ mesothelial cells account for the majority and help remodel its immune microenvironment. (mendeley.com)
  • Chronic liver disease is characterized by liver cell necrosis, inflammation, or scarring (fibrosis or cirrhosis), due to any cause, that persists for more than 6 months. (ultimatedisabilityguide.com)
  • Abdominal examination was are local formation of immune complexes done to detect cases of enlarged liver or induced by viral antigens, or a local tissue spleen and presence of ascites as complica- inflammation induced by autoantibodies tions of liver cirrhosis. (who.int)
  • AILD is a type of peripheral T-cell lymphoma that is clinically characterized by high fever and generalized lymphadenopathy. (medscape.com)
  • Leukocytoclastic vasculitis and renal cell carcinoma. (florence.com.tr)
  • Renal cell carcinoma (RCC) is the most common subtype of adult renal tumors, and its detection rate in the early stages has been increased in the dawn of advanced imaging modalities. (ijpmonline.org)
  • Here, we take the opportunity to report an unusual association of heavy chain deposition disease (HCDD) with clear cell subtypes of renal cell carcinoma in a 48-year-old male of Indian ethnicity. (ijpmonline.org)
  • Primary renal tumors account for 2%-3% of all human malignancy, and the major subtype is renal cell carcinoma (RCC). (ijpmonline.org)
  • To the best of our knowledge, this is one of the first reports demonstrating concurrent heavy chain deposition disease (HCDD) with clear cell subtypes of renal cell carcinoma in a 48- year-old male of Indian ethnicity. (ijpmonline.org)
  • KEYTRUDA plus LENVIMA is approved in the U.S., the EU, Japan and other countries for the treatment of advanced renal cell carcinoma (RCC) and certain types of advanced endometrial carcinoma. (streetinsider.com)
  • By combining MRI, MRS and optical imaging, we are studying the tumor microenvironment to understand the role of hypoxia, tumor vascularization, macromolecular transport and tumor metabolism in tumor progression, metastasis and ascites formation in orthotopic models of cancer. (hopkinsmedicine.org)
  • In this review we discuss the current knowledge in the area of peripheral immune-based biomarkers, drawing information from the results of recent clinical studies of a number of different immunotherapy modalities in the treatment of cancer, including checkpoint inhibitors, bispecific antibodies, chimeric antigen receptor T cells, and anti-cancer vaccines. (biomedcentral.com)
  • Of these, RNA-seq, flow and mass cytometry, and enzyme-linked immunosorbent assay-based multiplex technologies are frequently utilized to identify peripheral immune markers associated with clinical response to immune modulating therapies. (biomedcentral.com)
  • Results We found that the combination administration of SHP099 and AZD4547 significantly inhibited cancer cell proliferation in vitro in FGFR2i-resistant model derived from ascites of a female GC patient with FGFR2 amplification, two FGFR2-amplified GC cell lines and GC cells transfected with one kind of FGFR2 fusion. (bmj.com)
  • MIP-1 proteins have been reported to have multiple effects on hematopoietic precursor cells and MIP-1 alpha has been identified as a stem cell inhibitory factor that can inhibit the proliferation of hematopoietic stem cells in vitro as well as in vivo . (rndsystems.com)
  • Protein deficiency, kidney diseases (nephrotic syndrome, chronic glomerulonephritis), heart failure, myxedema, gastrointestinal diseases (pancreatitis, Crohn's disease, chronic diarrhea), lymphostasis associated with compression of the thoracic lymphatic duct, lymphangiectasis and difficulty in lymph outflow from the abdominal cavity predispose to the development of ascites. (medic-journal.com)
  • Cancer is a group of diseases involving abnormal cell growth with the potential to invade or spread to other parts of the body. (anti-cancers.com)
  • In a number of diseases, the secretory, resorptive and barrier functions of the peritoneum are disrupted, which leads to ascites. (medic-journal.com)
  • s how these cells impact diseases with an inflammatory element, such as cancer, cardiovascular disease and obesity. (hopkinsmedicine.org)
  • TIGIT can inhibit CD8+ T cell proliferation and activation by directly acting on TCR expression itself as engagement of TIGIT induces a down-regulation of the TCR- chain and molecules that comprise the TCR complex (18). (greatlakeshighereducationnow.com)
  • TIGIT expressed on CD4+ T cells induces IL-10 and suppresses IL-12 production by DCs CD155 ligation and thereby inhibits CD4+ T cell proliferation and IFN- production (21). (greatlakeshighereducationnow.com)
  • Methods Cell Counting Kit-8 and Annexin V-FITC Apoptosis Detection Kit were used to evaluate cell proliferation and apoptosis. (bmj.com)
  • Of the macrophages in tumours and ascites that exhibited distinct functional states, ascites-enriched macrophages were more of embryonic origin. (mendeley.com)
  • We are trying to identify virulence genes (genes that evolved in response to the host environment) by screening transposon mutants of C. glabrata for mutants that are specifically altered in adherence to epithelial cells, in survival in the presence of macrophages and PMNs. (hopkinsmedicine.org)
  • Research projects include studies of viral molecular genetics and host cell genes and proteins involved in the pathogenesis of disease. (hopkinsmedicine.org)
  • Transplanting their own (autologous) bone marrow-derived stem cells into 48 patients with end-stage liver disease resulted in therapeutic benefit to a high number of the patients, report researchers publishing in the current issue of Cell Transplantation (19:11). (medicaldaily.com)
  • [ 6 ] The lymphomatous infiltrate in some bone marrow specimens from these AILD patients contained numerous small or scattered large B cells, and these cells resembled either benign lymphoid aggregates or T-cell-rich large B-cell lymphoma, respectively. (medscape.com)
  • Paroxysmal nocturnal hemoglobinuria (PNH) is a clonal hematopoietic stem cell (HSC) disease. (medscape.com)
  • High TIGIT expression on peripheral CD8+ T cells is associated with primary refractory disease in acute myelogenous leukemia (AML) patients (62). (greatlakeshighereducationnow.com)
  • Disease of HUVECs with this pathogen led to a dramatic reduce (85% at 30 h and 95% at 48 h) in the amount of cell-associated Ang-2 (Fig. 3and = 3. (careersfromscience.org)
  • Thus, with ascites, respiratory and heart failure, pronounced metabolic disorders can develop, which worsens the prognosis of the underlying disease. (medic-journal.com)
  • 2014 BD launched the first FDA-approved drug coated balloon for peripheral artery disease. (bd.com)
  • Ovarian cancer (OC) is an aggressive gynecological tumour usually diagnosed at a late stage with widespread metastases and ascites. (mendeley.com)
  • Intercellular tissue dynamics of certain T cells, like GZMK+ effector memory T cell (Tem) and exhausted T cell (Tex), revealed potential roles of ascites as a pool for tumour-infiltrating T cells. (mendeley.com)
  • Our study provides additional insights for ascites ecosystem and its connection with other tumour-relevant tissues, as well as potential markers for efficacy evaluation and therapies overcoming resistance in OC. (mendeley.com)
  • Tumour lysis syndrome (TLS) is an oncological emergency characterized by hyperuricemia, hyperkalemia, hyperphosphatemia and hypocalcemia due to rapid destruction of tumour cells. (apjpch.com)
  • Peripheral neuropathy (disorder of peripheral nerves ) is often prominent, causing weakness in the feet and later in the arms. (dermnetnz.org)
  • The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography. (bdbiosciences.com)
  • Store undiluted at 4°C. The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography. (bdbiosciences.com)
  • The duration of hospitalization, analysis of medications in more tissue damage can occur up to end organs may be present because of peripheral vision tremors neuromuscular changes muscular atrophy spinal muscular in flixonase where to buy usa atrophies amyotrophic lateral sclero-sis. (elastizell.com)
  • Main toxicities were (sorafenib-GEMOX/sorafenib) neutropenia (23%/0), thrombocytopenia (33%/0), diarrhoea (18%/9), peripheral neuropathy (5%/0) and hand-foot syndrome (5%/18). (nature.com)
  • Given the immunosuppressive role of SHP2 under PD-1 signaling induction, we also proved that SHP099 treatment can significantly increase the secretion level of IFN-γ and downregulated the expression of PD-1 in human CD8+ T cells. (bmj.com)
  • that genetic deletion and pharmacological inhibition of beta-amyloid cleaving enzyme (BACE1) markedly accelerate axonal regeneration in the injured peripheral nerves of mice. (hopkinsmedicine.org)
  • Differential diagnoses include cryoglobulinemia, warfarin-induced necrosis, purpura fulminans, emboli to the skin, thrombocythemia, protein C deficiency, Sneddon syndrome, and skin ulcers in patients with sickle cell anemia or hemolytic anemia. (medscape.com)
  • Single-cell gene expression and immune repertoire measurements were conducted using the Chromium Single Cell V(D)J Reagent Kit (10x Genomics) following the manufacturer's instructions. (mendeley.com)
  • The gene expression matrices of the cells were generated with log normalization and linear regression using the NormalizeData and ScaleData functions of the Seurat package. (mendeley.com)
  • Recently, the analysis of TMB and T-cell gene expression provided value in identifying patients most likely to respond to pembrolizumab, suggesting the potential value for these biomarkers in the selection of patients for checkpoint therapy [ 5 ]. (biomedcentral.com)
  • The detection of monoclonal immunoglobulins ( antibodies ) confirm the presence of a monoclonal plasma cell proliferative disorder. (dermnetnz.org)
  • The distribution on lymphocytes for canine is similar to that found for both human and monkey, with the majority of CD4-positive lymphocytes being CD8-negative and lacking reactivity with antibodies to B- or NK-cell markers. (bdbiosciences.com)
  • When fluorochrome conjugated antibodies are bound to BD® CompBeads, they have spectral properties very similar to cells. (bdbiosciences.com)
  • 3. Furthermore, aliquots from the whole-cell lysates had been subjected to Western blot with antibodies against Ang-2 and FOXO1 (myc tag antibody). (careersfromscience.org)
  • Please refer to the Separation Flow Chart to identify the separated cell populations represented in this figure. (bdbiosciences.com)
  • PD-1 and IFN-γ expressions of T cells were detected by flow cytometry. (bmj.com)
  • 2022 BD becomes the first company to combine flow cytometry with fluorescence imaging and image-based decisioning to sort individual cells based on visual details of the cell at exceptionally high speed (15,000 cells per second). (bd.com)
  • A significant number of non-neoplastic T cells (resting CD4 + T cells and activated small- or medium-sized CD8 + lymphocytes) may coexist with a minor neoplastic T-cell population. (medscape.com)
  • The CD8α and β chains (CD8a and CD8b, respectively) form a heterodimer on the surface of most thymocytes and a subpopuplation of mature T-lymphocytes (ie, MHC class I-restricted T cells, including most T suppressor/cytotoxic cells). (bdbiosciences.com)
  • Additionally, the MIP-1 proteins have been reported to have chemoattractant and adhesive effects on lymphocytes, with MIP-1 alpha and MIP-1 beta preferentially attracting CD8 + and CD4 + T cells, respectively. (rndsystems.com)
  • AILD has been reported to occur concurrently with plasma cell leukemia. (medscape.com)
  • The interaction of CD54 and the corresponding ligand CD11a/CD18 expressed on γδ T cells is responsible for triggering effector function in γδ T cells. (aacrjournals.org)
  • property of TIGIT blockade is that it enhances not only anti-tumor effector T-cell responses, but also NK-cell responses, and reduces the suppressive capacity of regulatory T cells. (greatlakeshighereducationnow.com)
  • A significant increase in intra-abdominal pressure with ascites can lead to the development of umbilical or femoral hernias, varicocele, hemorrhoids, rectal prolapse. (medic-journal.com)