• N. gonorrhoeae is the causative agent of gonorrhea and N. meningitidis is one cause of bacterial meningitis. (wikipedia.org)
  • Since my return to Holland, I have been focusing on outer membrane biogenesis in a closely related bacterium, Neisseria meningitidis . (sciencewatch.com)
  • We have already developed a fruitful collaboration with the pharmaceutical company GlaxoSmithKline to develop vaccines against Neisseria meningitidis , a bacterium causing sometimes fatal meningitis and sepsis, especially in very young children. (sciencewatch.com)
  • One major aspect of this work centers on the pathogenic Neisseria, Neisseria gonorrhoeae and Neisseria meningitidis. (bu.edu)
  • Moraxella catarrhalis and Neisseria meningitidis can be confused with N. gonorrhoeae on Gram stain. (firebaseapp.com)
  • Identification of Neisseria meningitidis. (firebaseapp.com)
  • CONTAINS TWO IMPORTANT PATHOGENS Nesseria meningitidis Nesseria gonorrhoeae 5. (firebaseapp.com)
  • genus Neisseria (together, for example, with Neisseria meningitidis ). (wikilectures.eu)
  • The main difference between Neisseria Gonorrhoeae and Neisseria Meningitidis is that N. gonorrhoeae causes gonorrhea whereas N. meningitidis causes cerebrospinal meningitis. (pediaa.com)
  • N. gonorrhoeae and N. meningitidis are two types of closely-related organisms with different pathogenicity . (pediaa.com)
  • Gonorrhoeae and N. meningitidis are two types of closely-related bacteria. (pediaa.com)
  • N. gonorrhoeae refers to a bacterial pathogen responsible for gonorrhea, while N. meningitidis refers to the bacteria that causes the illness cerebrospinal meningitis. (pediaa.com)
  • N. gonorrhoeae is kidney-shaped, and opposing ends are concave, while N. meningitidis is semicircular with opposing ends. (pediaa.com)
  • N. gonorrhoeae does not contain a capsule, while N. meningitidis contains a capsule. (pediaa.com)
  • Moreover, N. gonorrhoeae forms a smooth, round, uniform, and moist colonies that are brown in color while N. meningitidis forms large, brown-color colonies. (pediaa.com)
  • N. gonorrhoeae does not undergo maltose fermentation, while N. meningitidis undergoes maltose fermentation. (pediaa.com)
  • N. gonorrhoeae causes gonorrhoea, but N. meningitidis causes cerebrospinal meningitis. (pediaa.com)
  • In brief, N. gonorrhoeae and N. meningitidis are two types of closely related bacteria. (pediaa.com)
  • On its surface, N. gonorrhoeae bears hair-like pili, surface proteins with various functions, and sugars called lipooligosaccharides. (wikipedia.org)
  • Dynamic polymeric protein filaments called type IV pili allow N. gonorrhoeae to adhere to and move along surfaces. (wikipedia.org)
  • To move, individual bacteria use their pili like a grappling hook: first, they are extended from the cell surface and attach to a substrate. (wikipedia.org)
  • N. gonorrhoeae is able to pull 100,000 times its own weight, and the pili used to do so are amongst the strongest biological motors known to date, exerting one nanonewton. (wikipedia.org)
  • Neisseria gonorrhoeae with numerous pili extending from the cell surface. (medscape.com)
  • Pili - type Fig 4: Gram Stain of N gonorrhoeae. (firebaseapp.com)
  • Pili are attractive targets for vaccines and therapeutics because of the key role they play in bacterial virulence as well as their prominent cell surface exposure, as shown in this scanning electron micrograph of Neisseria gonorrhoeae diplococci. (medscape.com)
  • This bacterium infects host cells by sticking them with pili. (pediaa.com)
  • Type IV pili are composed almost exclusively of a single protein called the major pilin, which forms a helical fiber that extends from the cell surface [ 6 ]. (biorxiv.org)
  • Blom, A. M. , Rytkönen, A., Vasquez, P., Dahlbäck, B. and Johnsson, A-B. (2001) A novel interaction between type IV pili of Neisseria gonorrhoeae and complement regulatory protein - C4b-binding protein. (lu.se)
  • Neisseria gonorrhoeae, also known as gonococcus (singular), or gonococci (plural), is a species of Gram-negative diplococci bacteria isolated by Albert Neisser in 1879. (wikipedia.org)
  • This agar preparation facilitates the growth of Neisseria species while inhibiting the growth of contaminating bacteria and fungi. (wikipedia.org)
  • The exact formulation has changed over the years but includes agents active against gram-positive bacteria (vancomycin), gram-negative bacteria (colistin, trimethoprim), and fungi (nystatin, anisomycin) at concentrations that do not inhibit N gonorrhoeae . (medscape.com)
  • This colored scanning electron micrograph shows the round bacteria that causes gonorrhea, Neisseria gonorrhoeae, on the surface of a cell. (nationalgeographic.com)
  • Gram-positive bacteria have a rigid and thick cell wall that impedes classic expansion strategies. (uni-wuerzburg.de)
  • Once ingested, these bacteria invade intestinal epithelial cells and translocate to the liver, where they grow inside hepatic cells. (pressbooks.pub)
  • Bacteria, the ones I know about, are haploid however many nuclei they have per cell. (asmblog.org)
  • Se hela listan på catalog.hardydiagnostics.com Gram stain for Neisseria gonorrhoeae is a quick and inexpensive test that works by detecting Gram-negative diplococci (the gonorrhoea bacteria) under a microscope. (firebaseapp.com)
  • The presence of bacteria resembling Neisseria gonnorhoeae in a man is diagnostic of gonnorhoea, however in women it is more difficult to diagnose, having a mixture of bacterial organisms present. (firebaseapp.com)
  • Bacteria are microorganisms that have circular double-stranded DNA and (except for mycoplasmas) cell walls. (msdmanuals.com)
  • Neisseria gonorrhoeae is a species of Gram-negative diplococci non-motile bacteria from the genus Neisseria . (roboscreen.com)
  • Neisseria gonorrhoeae is a species of gram negative diplococci, which are non encapsulated, non motile and kidney shaped bacteria. (howmed.net)
  • As for many other gram-positive bacteria, the cell wall of L. monocytogenes contains large amounts of the anionic polymer teichoic acid (TA), covalently linked to peptidoglycan. (asm.org)
  • This product was developed to address the problem of bacteria in cell culture. (cell-systems.com)
  • Cells have, as a natural and normal part of their constitutive programming, the ability to enclose bacteria adherent to their luminal surface in membrane, and sink them into the cytoplasm. (cell-systems.com)
  • Dosage of Bac-Off® was established by identifying the MIC for bacteria and the toxicity dosage for human microvascular cells. (cell-systems.com)
  • The color, size, and shape of the cells help identify the bacteria. (medlineplus.gov)
  • This may be a sign of a joint infection, for example, gonococcal arthritis due to bacteria called Neisseria gonorrhoeae or arthritis due to bacteria called Staphylococcus aureus . (medlineplus.gov)
  • N. gonorrhoeae can cause infection of the genitals, throat, and eyes. (wikipedia.org)
  • Neisseria gonorrhoeae culture is indicated in the diagnosis of N gonorrhoeae infection. (medscape.com)
  • Positive culture indicates active infection with N gonorrhoeae . (medscape.com)
  • Gonorrhea is a common N gonorrhoeae infection that is transmitted almost exclusively by sexual contact or perinatally and primarily affects the mucous membranes of the urethra and cervix and, less frequently, those of the rectum, oropharynx, and conjunctivae. (medscape.com)
  • Multidrug-resistant Neisseria gonorrhoeae infection with ceftriaxone resistance and intermediate resistance to azithromycin, Denmark, 2017. (cdc.gov)
  • Infection with two strains of Neisseria gonorrhoeae was found in paired cultures from 8.7% (6/69) of women who had infections of the cervix, rectum, or urethra. (bmj.com)
  • Pore-forming toxins (PFT) permeabilize host membranes during infection thereby causing concentration-dependent effects in host cell membranes ranging from disordered ion fluxes to cytolysis. (uni-wuerzburg.de)
  • No evidence of N gonorrhoeae infection by culture, gram stain of a smear of the discharge, or antigen or nucleic acid detection. (firebaseapp.com)
  • Mar 6, 2020 Gonorrhea is a common sexually transmitted infection caused by the gram- negative intracellular diplococcus Neisseria gonorrhoeae. (firebaseapp.com)
  • The anti-inflammatory compound curcumin inhibits Neisseria gonorrhoeae-induced NF-kappa B signaling, release of proinflammatory cytokines/chemokines and attenuates adhesion in late infection. (mpg.de)
  • Host cell signaling in Helicobacter pylori infection. (mpg.de)
  • Neisseria gonorrhoeae (Gc) is the causative agent of the sexually transmitted infection gonorrhea. (emerging-researchers.org)
  • Apart from that, surface-exposed proteins such as Opa and Opc and several virulence factors also help in the infection of the host cell by the bacterium. (pediaa.com)
  • BackgroundEpidemiology of Neisseria gonorrhoeae (NG) infection remains inadequately understood.AimWe aimed to characterise NG epidemiology in Europe.MethodsWe used Cochrane and PRISMA guidelines to systematically review, report, synthesise and analyse NG prevalence data from 1949 to 30 September 2021. (bvsalud.org)
  • Urethral inflammation that is not the result of infection with Neisseria gonorrhoeae . (cdc.gov)
  • Raw data and statistical analysis of Siglec-Fc binding assays with Neisseria gonorrhoeae strains. (datadryad.org)
  • Differences in nitric oxide steady states between arginine, hypoxanthine, uracil auxotrophs (AHU) and non-AHU strains of Neisseria gonorrhoeae during anaerobic respiration in the presence of nitrite. (rochester.edu)
  • It causes a sexually transmitted disease, gonorrhea, which remains a major global public health concern since many identified strains of N. gonorrhoeae are resistant to most available antibiotics [8]. (roboscreen.com)
  • My role in this research project consisted of attempting to create three strains of Neisseria gonorrhoeae (Gc) that constitutively express a single opa protein. (emerging-researchers.org)
  • N gonorrhoeae causes the sexually transmitted disease gonorrhea, among other diseases. (medscape.com)
  • Is Neisseria gonorrhoeae initiating a future era of untreatable gonorrhea? (cdc.gov)
  • Neisseria gonorrhoeae causes the sexually transmitted disease gonorrhea exclusively in humans and uses multiple strategies to infect, including acquisition of host sialic acids that cap and mask lipooligosaccharide termini, while restricting complement activation. (datadryad.org)
  • Neisseria gonorrhoeae (GC) is the etiologic agent of gonorrhea, still one of the most prevalent infectious diseases in the U.S. Untreated infections in women can lead to pelvic inflammatory disease (PID), a significant cause of infertility in this country. (rochester.edu)
  • I worked there on the interaction of the gonorrhea-causing bacterium Neisseria gonorrhoeae with human host cells. (sciencewatch.com)
  • Other gram-negative diplococcic are present in the field, but are not associated with PMN cells and are not diagnostic of gonorrhea. (firebaseapp.com)
  • Generally , N. gonorrhoeae is a bacterial pathogen that causes gonorrhea. (pediaa.com)
  • Of the 11 species of Neisseria that colonize humans, only two are pathogens. (wikipedia.org)
  • Microscopic cervicitis (≥10 polymorphonuclear leukocytes/epithelial cell) and normal (predominantly lactobacillary) microbiota were the most frequent findings in the samples in which the pathogens were detected alone or in multiple infections, except for samples with Trichomonas vaginalis in which the coccobacillary microbiota was the most common. (hindawi.com)
  • Since PFTs from several pathogens have been shown to recruit membrane repair components, we here investigated whether staphylococcal α-toxin is able to induce these mechanisms in endothelial cells. (uni-wuerzburg.de)
  • This is reinforced by Lactobacilli through the production of hydrogen peroxide (H 2 O 2 ), bacteriocins and biosurfactants, as well as the inhibition of the physical attachment of pathogens to the epithelium by competitive exclusion and the promotion of the engulfment and degradation of infected epithelial cells (autophagy). (frontiersin.org)
  • Obligate intracellular pathogens are able to grow, reproduce, and cause disease only within the cells of the host. (msdmanuals.com)
  • Facultative intracellular pathogens are able to live and reproduce either inside or outside of host cells. (msdmanuals.com)
  • N. gonorrhoeae is often isolated along with obligate anaerobes, which presents a conundrum, as the gonococcus has been considered to be an obligate aerobe. (rochester.edu)
  • The bacterium Neisseria gonorrhoeae (gonococcus), was discovered in 1879 by the German physician Albert Neisser, after whom it is also named. (wikilectures.eu)
  • N. gonorrhoeae is a gonococcus bacterium that is a species of Gram-negative diplococci. (pediaa.com)
  • In men, the best specimen for N gonorrhoeae culture is urethral exudate or urethral scrapings (obtained with a loop or special swab). (medscape.com)
  • All of the gram-negative diplococci were confirmed to be N gonorrhoeae by sugar fermentation studies. (firebaseapp.com)
  • The N gonorrhoeae are the intracellular gram-negative diplococci within the cytoplasm of the polymorphonuclear (PMN) cell marked with the small arrow. (firebaseapp.com)
  • Raw data of phagocytosis assay with THP-1 cells expressing Siglec-14 challenged with gonococcal porins. (datadryad.org)
  • Paired gonococcal cultures from each patient were characterised by auxotyping, susceptibility to four antibiotics, and acrylamide gel electrophoresis patterns of the gonococcal cell proteins. (bmj.com)
  • We are using a combination of genetic, physiologic, and cell biology techniques to better understand the role of the denitrification pathway in gonococcal virulence. (rochester.edu)
  • Role of ribosomal protein L12 in gonococcal invasion of Hec1B cells. (rochester.edu)
  • Type 1 fimbrial adhesin allows the fimbriae of ETEC cells to attach to the mannose glycans expressed on intestinal epithelial cells. (pressbooks.pub)
  • High estrogen states, as seen during puberty and pregnancy, promote the preservation of a homeostatic (eubiotic) vaginal microenvironment by stimulating the maturation and proliferation of vaginal epithelial cells and the accumulation of glycogen. (frontiersin.org)
  • At puberty and during pregnancy, elevated levels of estrogen promote the maturation of and deposition of glycogen in vaginal epithelial cells. (frontiersin.org)
  • Glycogen from exfoliated and lysed epithelial cells is catabolized by α-amylase in the vaginal lumen to smaller polymers that are subsequently metabolized to lactic acid by Lactobacillus spp. (frontiersin.org)
  • Lactic acid and cytolysin produced by Lactobacilli stimulate the dissolution of epithelial cells by lysis and enhance the availability of glycogen. (frontiersin.org)
  • Analysis of the type IV secretion system-dependent cell motility of Helicobacter pylori-infected epithelial cells. (mpg.de)
  • Nuclear factor-kappa B directs carcinoembryonic antigen-related cellular adhesion molecule 1 receptor expression in Neisseria gonorrhoeae-infected epithelial cells. (mpg.de)
  • Helicobacter pylori-induced prostaglandin E-2 synthesis involves activation of cytosolic phospholipase A(2) in epithelial cells. (mpg.de)
  • Translocation of the Helicobacter pylori CagA protein in gastric epithelial cells by a type IV secretion apparatus. (mpg.de)
  • Edwards VL , Wang LC, Dawson V, Stein DC, Song W. Neisseria gonorrhoeae breaches the apical junction of polarized epithelial cells for transmigration by activating EGFR. (umaryland.edu)
  • Bernegger S, Vidmar R, Fonovic M, Posselt G, Turk B, Wessler S . Identification of Desmoglein-2 as a novel target of Helicobacter pylori HtrA in epithelial cells. (plus.ac.at)
  • Meanwhile, it helps to repair the damaged epithelial cells. (robocup2009.org)
  • The major anaerobically induced outer membrane protein (AniA) from pathogenic Neisseria gonorrhoeae is essential for cell growth under oxygen limiting conditions in the presence of nitrite and is protective against killing by human sera. (rcsb.org)
  • My training in cell culture, molecular and cellular biology, microbiology and more recently bioinformatics has provided me the tools to conduct and implement multi-disciplinary research. (umaryland.edu)
  • Molecular characterization of two high-level ceftriaxone-resistant Neisseria gonorrhoeae isolates detected in Catalonia, Spain. (cdc.gov)
  • isolated on selective media for N. gonorrhoeae, isolates of other Neisseria spp. (firebaseapp.com)
  • Nearly twenty-five individual isolates of ACBRI Primary Human Microvascular cells have been probed to date. (cell-systems.com)
  • It inhibits the multiplication of Neisseria gonorrhoeae. (nih.gov)
  • Breshears LM, Edwards VL , Ravel J, Peterson ML. Lactobacillus crispatus inhibits growth of Gardnerella vaginalis and Neisseria gonorrhoeae on a porcine vaginal mucosa model. (umaryland.edu)
  • Trouw L., Nilsson S., Goncalvez I., Landberg G. and Blom A. M. (2005) C4b-binding protein binds to necrotic cells and DNA, which limits DNA release and inhibits complement activation. (lu.se)
  • It causes the sexually transmitted disease gonorrhoeae , known as gonorrhoea in Czech. (wikilectures.eu)
  • We conclude that in early biofilms the density and rupture force of bacterial surface structures can trigger cell sorting based on similar physical principles as in developing embryos. (elifesciences.org)
  • One such function is tissue-specific bacterial engulfment in human cells which do not normally undergo phagocytosis. (umich.edu)
  • NOTE: For purposes of this indication, a clinical diagnosis of bacterial vaginosis is usually defined by the presence of a homogeneous vaginal discharge that (a) has a pH of greater than 4.5, (b) emits a "fishy" amine odor when mixed with a 10% KOH solution, and (c) contains clue cells on microscopic examination. (hipaaspace.com)
  • Gram's stain results consistent with a diagnosis of bacterial vaginosis include (a) markedly reduced or absent Lactobacillus morphology, (b) predominance of Gardnerella morphotype, and (c) absent or few white blood cells. (hipaaspace.com)
  • Bac-Off® is formulated at MIC (minimum inhibitory concentration) to inhibit the growth of most bacterial agents and control contamination in cell culture, without harming the cells. (cell-systems.com)
  • This is a much wider gap between the dosage active against bacterial growth and the dosage toxic to mammalian cells than all other commonly used antibiotic classes. (cell-systems.com)
  • One of the genes regulated by PrfA is hyl , which encodes a toxin known as listeriolysin O (LLO), which allows the bacterium to escape vacuoles upon entry into a host cell. (pressbooks.pub)
  • Opacity-associated (Opa) proteins of Neisseria gonorrhoeae and N. meningitides are eight-stranded outer membrane proteins that bind to different host receptors, triggering engulfment of the bacterium. (umich.edu)
  • N. gonorrhoeae is an aerobic bacterium that is oxidase positive. (pediaa.com)
  • N. gonorrhoeae is a kidney-shaped bacterium that has opposing ends. (pediaa.com)
  • Identification of a conserved protein involved in anaerobic unsaturated fatty acid synthesis in Neiserria gonorrhoeae: implications for facultative and obligate anaerobes that lack FabA. (rochester.edu)
  • We further observed that thereby the lysosomal protein acid sphingomyelinase (ASM) was released into the cell culture medium. (uni-wuerzburg.de)
  • Recall that an adhesin is a protein or glycoprotein found on the surface of a pathogen that attaches to receptors on the host cell. (pressbooks.pub)
  • Recall that fimbriae are hairlike protein bristles on the cell surface. (pressbooks.pub)
  • Stelzner K, Winkler AC, Liang C, Boyny A, Ade CP, Dandekar T, Fraunholz MJ , Rudel T . Intracellular Staphylococcus aureus Perturbs the Host Cell Ca 2+ Homeostasis To Promote Cell Death. (uni-wuerzburg.de)
  • Jan 14, 2021 Fig 2: N gonorrhoeae virulence factors. (firebaseapp.com)
  • Cell Commun Signal , 2021, 19: 108. (plus.ac.at)
  • Les patients qui ont accepté de participer après apptéléphonique ont été inclus de janvier à mai 2021.Les variables d'étudeétaient: âge, sexe, acuité visuelle (AV), caractéristiques de la LCET selon Diallo, pronostic fonctionnel et anatomique en post puberté (plus de 15 ans). (bvsalud.org)
  • Other organisms sensitive in vitro to penicillin V are Corynebacterium diphtheriae, Bacillus anthracis, Clostridia, Actinomyces bovis, Streptobacillus moniliformis, Listeria monocytogenes, Leptospira and Neisseria gonorrhoeae. (nih.gov)
  • We have identified a novel gene, gtcA , involved in the decoration of cell wall teichoic acid of Listeria monocytogenes serotype 4b with galactose and glucose. (asm.org)
  • The current focus is analyzing the role of the vaginal microbiome in modulating the susceptibility of host cells to sexually transmitted infections (STIs) which will eventually translate into better diagnostics, prevention, and therapeutics. (umaryland.edu)
  • Generally, the sexual transmission of N. gonorrhoeae occurs through oral, anal, and vaginal sex. (pediaa.com)
  • 95% CI: 1.00-1.04%), respectively.ConclusionsNeisseria gonorrhoeae epidemiology in Europe has distinct and contrasting epidemiologies for vaginal sex transmission in heterosexual sex networks vs anal and oral sex transmission in MSM sexual networks. (bvsalud.org)
  • N. gonorrhoeae is oxidase positive (possessing cytochrome c oxidase) and catalase positive (able to convert hydrogen peroxide to oxygen). (wikipedia.org)
  • From September 1995 through October 1997, samples for M genitalium, C trachomatis, and N gonorrhoeae were collected from 946 consecutive patients attending because of symptoms of sexually transmitted infections or for a check up. (bmj.com)
  • A new multidrug-resistant strain of Neisseria gonorrhoeae in Australia. (cdc.gov)
  • New clinical strain of Neisseria gonorrhoeae with decreased susceptibility to ceftriaxone, Japan. (cdc.gov)
  • Nakayama S , Shimuta K , Furubayashi K , Kawahata T , Unemo M , Ohnishi M . New ceftriaxone- and multidrug-resistant Neisseria gonorrhoeae strain with a novel mosaic penA gene isolated in Japan. (cdc.gov)
  • The DNA sequence of lsi-2 has been determined for N. gonorrhoeae 1291, a strain that expresses a high-molecular-mass LOS, and a derivative of this strain, RS132L, that produces a truncated LOS. (uky.edu)
  • Antibiotic resistance in N. gonorrhoeae is a growing public health concern, especially given its propensity to develop resistance easily. (wikipedia.org)
  • There is concern that increasing gonorrhoea prevalence will increase the likelihood of worsening antibiotic resistance in Neisseria gonorrhoeae . (biomedcentral.com)
  • Neisseria gonorrhoeae infects primarily the mucosal membranes. (howmed.net)
  • Other than the sexual transmission of N. gonorrhoeae , it infects the genitals, eyes, and throat. (pediaa.com)
  • Neisseria gonorrhoeae causes an acute, inflammatory disease of the urogenital tract called gonorrhoea . (wikilectures.eu)
  • Staphylococcus aureus is the commonest cause, though other organisms should be considered based on age (eg Group B streptococci in neonates, Kingella Kingae in 6 months to 4 years), immunisation status ( Haemophilus influenzae) and underlying illness (eg Salmonella in children with sickle-cell disease). (rch.org.au)
  • cis- and trans-acting elements involved in regulation of norB (norZ), the gene encoding nitric oxide reductase in Neisseria gonorrhoeae. (rochester.edu)
  • It is clear that the number of gene copies per cell could be significant for regulation of gene expression, but the effects of multiple haploid nuclei are insignificant compared to the consequences of real diploid nuclei which have two independently inherited and therefore possibly different copies of each gene. (asmblog.org)
  • We show that S. aureus α-toxin induced increase in cytosolic Ca2+ in endothelial cells, which was accompanied by p38 MAPK phosphorylation. (uni-wuerzburg.de)
  • Thus, our results show that staphylococcal α-toxin triggers mechanisms in endothelial cells, which have been implicated in membrane repair after damage of other cell types by different toxins. (uni-wuerzburg.de)
  • Exposure of endothelial cells to anti-b2GPI antibodies and their corresponding peptides leads to the inhibition of endothelial cell activation, as shown by decreased expression of the adhesion molecules E-selectin, intercellular adhesion molecule, and vascular cell adhesion molecule and of monocyte adhesion. (medscape.com)
  • The observed morphotypes were in remarkable agreement with the differential strength of adhesion hypothesis proposing that a tug-of-war among surface structures of different cells governs cell sorting. (elifesciences.org)
  • Opas bind to carcinoembryonic antigen cell adhesion molecules (CEACAM), which are neutrophil receptors. (emerging-researchers.org)
  • The authors explain how a mutation in a eukaryotic diploid cell is maintained as a heterozygous cell line because during mitosis all pairs of sister chromosomes (chromatids) become aligned and separated together in a plane perpendicular to the division plane making that every daughter cell inherits the mutation. (asmblog.org)
  • Neisseria gonorrhoeae lipooligosaccharide (LOS) undergoes antigenic variation at a high rate, and this variation can be monitored by changes in a strain's ability to bind LOS-specific monoclonal antibodies. (uky.edu)
  • Neisseria species are fastidious, Gram-negative cocci that require nutrient supplementation to grow in laboratory cultures. (wikipedia.org)
  • Mycoplasma species are the smallest free-living organisms and are unique among prokaryotes in that they lack a cell wall. (medscape.com)
  • Characterisation of Neisseria gonorrhoeae from women with simultaneous infections at two sites. (bmj.com)
  • D. Culture The current preferred laboratory method for the diagnosis of N. gonorrhoeae infections is the isolation and identification of the agent. (firebaseapp.com)
  • We hypothesized that gonococci selectively target human anti-inflammatory sialic acid-recognizing Siglec receptors on innate immune cells to blunt host responses, and that pro-inflammatory Siglecs and SIGLEC pseudogene polymorphisms represent host evolutionary adaptions to counteract this interaction. (datadryad.org)
  • However, little is known about the associated changes in the physics of cell-cell interaction and its impact on the architecture of biofilms. (elifesciences.org)
  • In vitro studies focus on the strength and specificity of the interaction, while our in vivo studies are elucidating the cell fate and signaling of Opa liposomes. (umich.edu)
  • A new type of technology can capture stray ovarian cancer cells from a simple blood test and successfully predict cancer in people who have a lesion or cyst in the pelvic region, according to a new study by a Wilmot Cancer Institute physician/scientist. (news-medical.net)
  • In L. monocytogenes , a polyribitol phosphate type of TA appears to be the prevalent accessory cell wall polymer ( 7 , 14 , 40 ). (asm.org)
  • Neisseria is non-spore-forming, capable of moving using twitching motility, and an obligate aerobe (requires oxygen to grow). (wikipedia.org)
  • 1, 2 Owing to the slow cell replication and fastidious growth requirements, culture is impossible to use in clinical practice. (bmj.com)
  • Dr. Aleksandra Sikora was recently published in Molecular and Cellular Proteomics for her work with other OSU College of Pharmacy researches on the human-specific pathogen Neisseria gonorrhoeae (GC). (oregonstate.edu)
  • N. gonorrhoeae can indeed engage multiple human but not chimpanzee CD33rSiglecs expressed on innate immune cells and in the genitourinary tract--including Siglec-11 (inhibitory) and Siglec-16 (activating), which we detected for the first time on human cervical epithelium. (datadryad.org)
  • Study mouthwash A was inhibitory against N. gonorrhoeae in vitro, whereas study mouthwash B was not. (biomedcentral.com)