• mutant
  • In addition, we show that decreased mutant keratin 14 expression resulted in normal morphology and functions of the skin. (rupress.org)
  • For the selection of recombinant embryonic stem (ES) cells, a neomycin-resistance (neo) cassette flanked by loxP sites (a gift from R.R. Behringer and Y. Mishina, University of Texas, M.D. Anderson Cancer Center, Houston, TX) was inserted into the PmlI site in intron I of the mutant K14 gene. (rupress.org)
  • protein
  • In EB simplex, there is a weakness in one of these proteins (usually type 5 or type 14 keratin, but very occasionally another protein called plectin), which causes affected cells to be less resilient to friction and to rupture when subjected to even minor physical stress. (skinsupport.org.uk)