Cell 1961 vesicular stomatitis indiana virus. Medical search. Frequent questions

BHK-21 cells are susceptible to human adenovirus D, reovirus 3, and vesicular stomatitis virus (Indiana strain). (wikipedia.org)
Foot-and-mouth disease (FMD) virus was partially inactivated by several methods: incubation with dilute formaldehyde or acetylethylene-imine, ultraviolet (U.V.) irradiation, heating, or by mixing with type specific antiserum, trypsin or extracts from cells susceptible to the virus. (microbiologyresearch.org)
The ability of the treated preparations to attach to susceptible cultivated pig kidney cells was examined. (microbiologyresearch.org)
The decrease in viral infectivity when FMD virus was treated with formaldehyde or acetylethyleneimine, U.V., or heat at 25° or 37° was proportional to the loss of infective RNA, with little impairment of its serological properties or its ability to attach to susceptible cells. (microbiologyresearch.org)
Cell viability indicated that tumor cell lines were differentially susceptible to each virus. (oncotarget.com)

A comparison of the yields of infectious ribonucleic acid from heated and ultraviolet irradiated mouse encephalomyelitis virus (GD VII strain). (microbiologyresearch.org)

BHK-21 cells are resistant to poliovirus 2 and Rabbit vesivirus (RaV). (wikipedia.org)

Here, we describe the safety, robust immunogenicity, and potent efficacy elicited in rhesus macaques by a modified vaccinia virus Ankara (MVA) vector expressing a full-length SARS-CoV-2 spike (S) protein (MVA-S). MVA-S vaccination was well tolerated and induced S and receptor-binding domain (RBD)-binding IgG antibodies and neutralizing antibodies against SARS-CoV-2 and several variants of concern. (frontiersin.org)
Vaccinia virus, a member of the Poxviridae family, has been extensively used as an oncolytic agent and has entered late stage clinical development. (oncotarget.com)
Numerous tumor cell lines were infected with ten non-vaccinia poxviruses to identify which virus displayed the most potential as an oncolytic agent. (oncotarget.com)
Vaccinia virus (VACV) is one of the best studied representative of the Orthopoxvirus genus. (oncotarget.com)

Mechanism of infection of pig kidney cells by foot-and-mouth disease virus. (microbiologyresearch.org)
Oncolytic virotherapy for cancer treatment utilizes naturally occurring or engineered viruses for selective infection and cancer cell death without any adverse effect on normal cells. (oncotarget.com)

Its potency to preferentially infect and kill cancer cells has been proven for many years and advanced clinical trials are ongoing to evaluate this virus in human [ 1 ]. (oncotarget.com)

BHK cells are also used to study viral infections. (wikipedia.org)
the viral RNA is still present in an infective form in these mixtures. (microbiologyresearch.org)
They contain most or all of the molecular machinery necessary for efficient and specific packaging of viral genomes, escape from an infected cell, survival of transfer to a new host cell, attachment, penetration, and initiation of a new replication cycle. (basicmedicalkey.com)

Traditional phenotypic assays selleck chemicals used to assess the susceptibility of mutant human immunodeficiency virus type-1 (HIV-1) obtained from infected patients or from resistance selection to antiviral agents in cell culture are rather tedious and time consuming. (mdmpathway.com)
To improve the efficiency of this process, a novel method was developed in which mutant viruses are captured with magnetic nano-beads and used to infect gag-GFP reporter cells to evaluate the extent of resistance conferred by the mutant viruses against antiviral agents. (mdmpathway.com)
Taken together, these findings suggest that a rapid, sensitive, non-invasive, and homogeneous phenotypic assay has been developed for assessing the antiviral agent susceptibility of mutant viruses that emerge from in vitro resistance Morin Hydrate selection studies. (mdmpathway.com)

Baby Hamster Kidney fibroblasts (BHK cells) are an adherent cell line used in molecular biology. (wikipedia.org)
In many cases, the molecular machinery works in part by subverting more elaborate elements of a host cell's apparatus for carrying out related processes. (basicmedicalkey.com)

After SARS-CoV-2 challenge, vaccinated animals showed a significant strong reduction of virus loads in bronchoalveolar lavages (BAL) and decreased levels in throat and nasal mucosa. (frontiersin.org)
It receives blood from a vein in the nasal cavity, runs backwards, and gradually increases in size as blood drains from veins of the brain and the DURA MATER. (bvsalud.org)

The Wyeth based vector Pexa-Vec (JX-594) has shown efficacy in hepatocarcinoma (HCC) [ 1 ] and a Phase 3 study is ongoing in primary HCC (National Clinical Trial NCT02562755). (oncotarget.com)

These findings favor the use of MVA-S as a potential vaccine for SARS-CoV-2 in clinical trials. (frontiersin.org)
Numerous preclinical and clinical trials have been performed in a variety of cancer indications using several strains of oncolytic VACV including Wyeth, Western Reserve, Lister, and Copenhagen strains [ 2 - 6 ]. (oncotarget.com)

Raccoonpox virus was the most potent of the tested poxviruses and was highly effective in controlling cell growth in all tumor cell lines. (oncotarget.com)

The term "oncotarget" encompasses all molecules, pathways, cellular functions, cell types, and even tissues that can be viewed as targets relevant to cancer as well as other diseases. (oncotarget.com)

While Crohn disease can affect any part of the GI tract (from the oral cavity to the anus), inflammation in UC is generally restricted to the colon and is specifically limited to the mucosa and submucosa. (medscape.com)

The cells are negative for reverse transcriptase, which means that they lack integral retrovirus genomes. (wikipedia.org)
Enveloped viruses have, in their lipid bilayer, an impermeable barrier between their genomes and the outside environment, reducing the need for continuity of any protein layer. (basicmedicalkey.com)

Studies with infective ribonucleic acid from tissues and cell cultures infected with the virus of foot-and-mouth disease. (microbiologyresearch.org)

Rheumatic manifestations frequently occur in patients with CLT in the absence of overt thyroid dysfunction and mimic the presentation of the well-defined connective tissue diseases. (mdmpathway.com)
7] Oral manifestations can prove crucial in diagnosis and usually parallel the intestinal disease course. (medscape.com)

Taking DHEA by mouth does not seem to improve mental function or decrease mental decline in healthy older people, people with HIV, or in healthy young adults. (medlineplus.gov)

MDM2 has p53-independent transcription factor-like effects in nuclear factor-kappa beta (NFκB) activation. (mdmpathway.com)

Methods for preserving viruses and other macromolecular assemblies by rapid freezing to liquid nitrogen or liquid helium temperatures have permitted visualization of electron-scattering contrast from the structures in the particle itself and not just from the cast created by a surrounding layer of negative stain. (basicmedicalkey.com)

Raynaud's phenomenon occurred in 28 % and sicca symptoms Interleukin-3 receptor in 26 % of patients. (mdmpathway.com)
Our study showed that US PS leads to a certain dysfunction on behavioral and neurochemical levels in rats that is most closely associated with symptoms of schizophrenia or autism. (bvsalud.org)

In human colon cancer xenograft model, a single intratumoral inoculation of the recombinant Raccoonpox virus, in combination with 5-fluorocytosine administration, produced relevant tumor growth control. (oncotarget.com)
Lesions in the colon consist of areas of hemorrhage and ulceration, along with abscesses. (medscape.com)

In addition, the reported adverse cases of thrombosis with the adenovirus vaccines ( 13 ) and myocarditis with the mRNA vaccines particularly in young individuals ( 14 ) indicate that a deeper understanding of the mechanisms of action of the vaccines should be undertaken. (frontiersin.org)

The role of the properties of magnetic nanoparticles in the remote magneto-mechanical actuation of biomolecules under the influence of external magnetic fields is still of particular interest. (bvsalud.org)
Here, a specially designed strategy based on the mechanical destruction of short oligonucleotide duplexes is used to demonstrate the effect of magnetic nanoparticles with different sizes (5-99 nm) on the magnitude of the magneto-mechanical actuations in a low-frequency alternating magnetic field. (bvsalud.org)

Traditional thin-sectioning methods are useful for examining infected cells and larger, isolated particles. (basicmedicalkey.com)
The thickness of a section and the coarseness of staining methods limit resolution to about 50 to 75 Å, even in the best cases. (basicmedicalkey.com)

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The mouth is frequently involved in conditions that affect the skin, but it is also affected by many systemic diseases. (medscape.com)

This TK-deleted Raccoonpox virus was notably attenuated in normal primary cells but replicated efficiently in numerous tumor cell lines. (oncotarget.com)
The oral cavity plays a critical role in numerous physiologic processes, including digestion, respiration, and speech. (medscape.com)

The BHK-21 cells are useful for transformations and for stable and temporary transfections. (wikipedia.org)
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Like Pexa-Vec, most of the oncolytic VACVs reported to date encode mutations that inactivated the TK, a critical enzyme in the salvage pathway for nucleotide biosynthesis. (oncotarget.com)

5] Nonspecific, reactive skin findings in patients with Crohn disease include erythema nodosum, pyoderma gangrenosum, and Sweet syndrome. (medscape.com)

The aim of our study was to investigate the effect of prenatal stress induced by exposure to variable frequency ultrasound (US PS) throughout the gestational period on the adult rat offspring, namely to identify features of behavioral alterations and neurochemical brain parameters that can be associated with certain mental disorders in humans, to determine the possibility of creating a new model of psychopathology. (bvsalud.org)
A correlation analysis of behavioral and neurochemical parameters in male and female rats was performed based on the data obtained. (bvsalud.org)

Growth and titration of the viruses of foot-and-mouth disease and vesicular stomatitis in kidney monolayer tissue cultures. (microbiologyresearch.org)

Several vaccines have now been approved for human use, including mRNA vaccines (BioNTech/Pfizer, Moderna), adenovirus-vector-based vaccines (AstraZeneca, Johnson & Johnson, CanSino Biologics, Gamaleya), and inactivated virus vaccines (Sinovac Biotech and Sinopharm). (frontiersin.org)

Our study included a study of some behavioral characteristics of male and female rats in the elevated plus maze, open field test, object recognition test, social interaction test, sucrose preference test, latent inhibition test, Morris water maze, forced swimming test, acoustic startle reflex and prepulse inhibition tests. (bvsalud.org)
In shop Luminescence with the based essay of hearing food can prevent qualified except just released by any Psychology And your response can get alone in 2014 Will keep the autoplay, at the interaction followed on the DESIGN. (holiday-reisezentrum.de)

The intergroup comparison showed significant differences in VAS pain, 6MWT, and EMS, among three groups. (mdmpathway.com)
The intergroup comparison showed significant difference in pain, physical function, and energy subgroups of SF-36. (mdmpathway.com)

DHEA levels seem to be lower in people with depression and after menopause. (medlineplus.gov)
Taking DHEA by mouth daily for up to 2 years doesn't seem to improve body shape, bone strength, muscle strength, or quality of life in people older than 60 who have low DHEA levels. (medlineplus.gov)

A .gov website belongs to an official government organization in the United States. (medlineplus.gov)

The tissue culture test for assaying the virus and neutralizing antibody of foot-and-mouth disease and its application to the measurement of immunity in cattle. (microbiologyresearch.org)

Dehydroepiandrosterone (DHEA) is a hormone that is turned into male and female sex hormones in the body. (medlineplus.gov)

Feature papers represent the most advanced research with significant potential for high impact in the field. (mdpi.com)
The results demonstrated significant antitumoral activity of this new modified Raccoonpox virus armed with FCU1 and this virus could be considered to be included into the growing armamentarium of oncolytic virotherapy for cancer. (oncotarget.com)
These differences were statistically significant in groups 2 and 3 compared with the group 1. (mdmpathway.com)

Negative staining, with uranyl acetate, potassium phosphotungstate, or related electron-dense compounds, gives somewhat more detailed images of isolated and purified virus particles. (basicmedicalkey.com)
Viruses embedded in negative stain are often relatively well preserved. (basicmedicalkey.com)

Taking DHEA by mouth doesn't improve muscle strength in adults. (medlineplus.gov)

Purification of the virus of foot-and-mouth disease by fluorocarbon treatment and its dissociation from neutralizing antibody. (microbiologyresearch.org)
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Cutaneous involvement consists of similar ulcerations that may arise on the buttocks, abdomen, thighs, and face, although in rare cases patients may develop pyoderma vegetans. (medscape.com)
In North America, the incidence of Crohn disease can be as high as 20.2 cases per 100,000 population. (medscape.com)

Application of agar gel precipitin tests to the study of the virus of foot-and-mouth disease. (microbiologyresearch.org)
In this study, we evaluated the potential oncolytic properties of other members of the Poxviridae family. (oncotarget.com)
Forty-six consecutive patients with anti-thyroid peroxidase (alpha TPO) and/or anti-thyroglobulin antibodies (alpha TG), and normal thyroid function in the absence of a well-defined connective tissue disease were included in a case-cohort study. (mdmpathway.com)

Plasmacytoid dendritic cells (pDCs) are the professional producers of IFN-I in response to many viruses, including all of the herpesviruses tested. (mdpi.com)

In the foreground is a color rendering of the three-dimensional image reconstruction, based on the kinds of micrographs shown in the background picture. (basicmedicalkey.com)

The most critical distinction, from a structural perspective, is between enveloped viruses-those with lipid-bilayer membranes-and nonenveloped viruses-those without such membranes. (basicmedicalkey.com)

The technique of complement fixation in foot-and-mouth disease research. (microbiologyresearch.org)
Editors select a small number of articles recently published in the journal that they believe will be particularly interesting to readers, or important in the respective research area. (mdpi.com)
The aim is to provide a snapshot of some of the most exciting work published in the various research areas of the journal. (mdpi.com)

It recently detected in professional Texas. (holiday-reisezentrum.de)

Arthritis was radiographically present in 88 %, affecting the spine in 45 % of patients. (mdmpathway.com)

DHEA can affect how insulin works in the body. (medlineplus.gov)
DHEA is a hormone that can affect how estrogen works in the body. (medlineplus.gov)

Find support for a specific problem in the support section of our website. (mdpi.com)
S-specific IFNγ, but not IL-4, -producing cells were also elicited. (frontiersin.org)

Recent breakthroughs in stem cell biology and cell reprogramming revolutionized the field. (bvsalud.org)

For the structure of any virus particle, a central constraint is that the information needed to specify its macromolecular components must not exhaust the genetic capacity of the packaged genome. (basicmedicalkey.com)
The shell of a nonenveloped virus with even a very small genome must therefore contain a large number of identical protein subunits-at least 60, if the coat-protein gene is to use up less than 25% of the coding capacity in the enclosed nucleic acid. (basicmedicalkey.com)
To investigate further the oncolytic capacity of the Raccoonpox virus, we have generated a thymidine kinase (TK)-deleted recombinant Raccoonpox virus expressing the suicide gene FCU1 . (oncotarget.com)

The serological properties of the treated virus preparations were studied by complement-fixation and agar diffusion tests and their content of infective ribonucleic acid (RNA) determined by phenol extraction. (microbiologyresearch.org)

Comparable EC(50) values were obtained when bead-captured breakthrough virus from in vitro resistance selection experiments and its matched site-directed mutagenesis virus CH5183284 datasheet were tested side by side in this assay. (mdmpathway.com)

Papers will now be published continuously within yearly volumes in their final and complete form and then quickly released to Pubmed. (oncotarget.com)

Computed tomography and histological examination of the lungs showed reduced lung pathology in MVA-S-vaccinated animals. (frontiersin.org)

Taking DHEA by mouth or applying it to the skin might improve skin appearance after menopause and in people over the age of 60 years. (medlineplus.gov)

Electron microscopy is the most direct way to determine the general morphology of a virus particle. (basicmedicalkey.com)

A positive ANA was found in 24 % of patients. (mdmpathway.com)

The main hypothesis of this phenomenon is associated with a key role of magneto-dipole interactions between individual nanoparticles, which blocks the movements of nanoparticles in dense clusters. (bvsalud.org)

A tightly condensed single-stranded RNA or DNA of this size will occupy a spherical volume about 90 Å in radius. (basicmedicalkey.com)
Resolution means the approximate minimum size of a substructure that can be separated in an image from its neighbor. (basicmedicalkey.com)

HN - 2008 MH - Transverse Sinuses UI - D054064 MN - A07.231.908.224.833 MS - The two large endothelium-lined venous channels that begin at the internal occipital protuberance at the back and lower part of the CRANIUM and travels laterally and forward ending in the internal jugular vein (JUGULAR VEINS). (bvsalud.org)

It also examined the differences in stability and energy consumption between patients with OA and healthy subjects. (mdmpathway.com)

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Organisms29

Diseases7

Chemicals and Drugs25

Analytical, Diagnostic and Therapeutic Techniques and Equipment5

Phenomena and Processes14

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