• giants
  • The earliest report of familial gigantism may be that of Goliath, described in in the Bible, where it is stated that his father and three brothers were also giants. (scielo.br)
  • treatments
  • Many treatments for gigantism receive criticism and are not accepted as ideal. (wikipedia.org)
  • Various treatments involving surgery and drugs have been used to treat gigantism. (wikipedia.org)
  • Treatments for gigantism include surgery, medication, and radiation therapy, although their effectiveness depends mostly on the progression of the disease - and usually, by the time clinicians get involved, it's already too late. (scienceworldreport.com)
  • skeleton
  • It's no tall tale-the first complete ancient skeleton of a person with gigantism has been discovered near Rome, a new study says. (blogspot.com)
  • evolutionary
  • Thus, island gigantism is usually an evolutionary trend resulting from the removal of constraints on the size of small animals related to predation and/or competition. (wikipedia.org)
  • From a biologist's perspective, polar gigantism fascinates because it is bizarre, and because gigantism is a potentially powerful tool for understanding the physical, ecological and evolutionary principles that govern the evolution of body size. (biologists.org)
  • whereas
  • Examples of island gigantism include: Many rodents grow larger on islands, whereas carnivores, proboscideans and artiodactyls usually become smaller. (wikipedia.org)
  • Gigantism was considered an exaggerated variant of normal development, whereas acromegaly was considered as a pathological condition. (scielo.br)
  • Indeed, current data indicate that some groups show gigantism at the poles whereas others show nanism. (biologists.org)
  • Though gigantism has also been reported from terrestrial organisms [e.g. lichens ( Øvstedal and Smith, 2001 )], we focus on organisms from the marine environment because the terrestrial Antarctic fauna is comparatively sparse, whereas the polar oceans are home to a fauna that is rich and often strange. (biologists.org)
  • known
  • In zoology, deep-sea gigantism, also known as abyssal gigantism, is the tendency for species of invertebrates and other deep-sea dwelling animals to display a larger size than their shallower-water relatives. (wikipedia.org)
  • It is not known whether deep-sea gigantism comes about as a result of adaptation for scarcer food resources (therefore delaying sexual maturity and resulting in greater size), greater hydrostatic pressure, or for other reasons. (wikipedia.org)
  • Smaller
  • Island gigantism is one aspect of the more general "island or Foster's rule", which posits that when mainland animals colonize islands, small species tend to evolve larger bodies, and large species tend to evolve smaller bodies. (wikipedia.org)
  • patients
  • It does not undergo diurnal variation and will thus be consistently elevated in GH hyper-secretion and therefore patients with gigantism. (wikipedia.org)
  • Pediatric gigantism patients have shown to have duplications of genes on a specific chromosome, Xq26. (wikipedia.org)
  • Additionally, DNA mutations in the aryl hydrocarbon receptor interacting protein (AIP) gene are common in gigantism patients. (wikipedia.org)
  • They have been found to be present in about 29 percent of patients with gigantism. (wikipedia.org)
  • Reduction of the levels of IGF-I as a result of pegvisomant administration can be incredibly beneficial for the pediatric gigantism patients. (wikipedia.org)
  • cases
  • Two partial skeletons, one from Poland and another from Egypt, have previously been identified as "probable" cases of gigantism, but the Roman specimen is the first clear case from the ancient past, study leader Simona Minozzi, a paleopathologist at Italy's University of Pisa, said by email. (blogspot.com)