• infection
  • Pneumococcal infection in children with no spleen. (ebscohost.com)
  • , Pneumococcal pneumonia is considered non-invasive when bacteria cause infection in the lungs but are not detected in the blood concurrently, or invasive when bacteria also enter the bloodstream or another normally sterile site in the body. (pfizer.ca)
  • This is not a simple left lower lobe pneumonia that is the reason why it is taking a longer time to resolve.Total duration of treatment can range from 6-8 weeks.The symptoms you are having of the pain and occasional fever is because of bronchiectasis which means some amount of lingering infection is still there that particular part of the lung . (justanswer.com)
  • Several markers of infection (pneumococcal DNA load in blood (real-time LytA PCR), white blood cell (WBC) count, C-reactive protein (CRP), procalcitonin (PCT) and soluble urokinase plasminogen activator receptor (suPAR) levels) were assessed for their ability to predict severe disease development. (deepdyve.com)
  • Pneumonia occurs if the organisms are inhaled into the lungs and not cleared (again, viral infection, or smoking-induced ciliary paralysis might be contributing factors). (wikipedia.org)
  • The risk of pneumococcal infection is much increased in persons with impaired IgG synthesis, impaired phagocytosis, or defective clearance of pneumococci. (wikipedia.org)
  • Damage to the lining of the airways (respiratory epithelium) and upper respiratory system caused by influenza may facilitate pneumococcal entry and infection. (wikipedia.org)
  • Confirmed Case: Meet the probable case definition plus have pneumococcal infection confirmed by blood culture or other isolation of pneumococci from normally sterile site. (wikipedia.org)
  • clinical
  • Until now, clinical failures of fluoroquinolones during treatment of pneumococcal infections have rarely been reported ( 1 - 3 ) and development of resistance in S . pneumoniae to quinupristin-dalfopristin and telithromycin during or after treatment with a macrolide or a combination of macrolide and quinolone antibiotics has never been reported. (cdc.gov)
  • Although β-lactam-plus-macrolide combination therapy for this disease is recommended in several guidelines, the clinical efficacy of this strategy against pneumococcal pneumonia remains controversial. (pubmedcentralcanada.ca)
  • However, little is known about the efficacy of strategies to diagnose pneumococcal pneumonia based on an initial comprehensive assessment combining clinical history, Gram staining of sputum and the urinary pneumococcal antigen test followed by treatment with high-dose penicillins as an initial monotherapy. (biomedcentral.com)
  • Person criteria may include age, gender, ethnicity, and clinical characteristics such as symptoms (e.g. cough and fever) and the results of clinical tests (e.g. pneumonia on chest X-ray). (wikipedia.org)
  • pneumoniae
  • As a significant human pathogenic bacterium S. pneumoniae was recognized as a major cause of pneumonia in the late 19th century, and is the subject of many humoral immunity studies. (wikipedia.org)
  • Typical Bacterial Infections: Haemophilus influenzae Staphylococcus aureus Klebsiella pneumonia Atypical Bacterial Infections: Legionella pneumophila Mycoplasma pneumoniae Chlamydophila pneumoniae Chlamydia psittaci Parasitic infections: Respiratory cryptosporidiosis Viral infections: Adenovirus Influenza A virus Influenza B virus Human parainfluenza viruses Human respiratory syncytial virus SARS coronavirus Middle East respiratory syndrome coronavirus Aspiration pneumonia Antibiotics do not help the many lower respiratory infections which are caused by parasites or viruses. (wikipedia.org)
  • prevention
  • In 2008, PACE launched its Global Call to Action on Pneumococcal Disease Prevention in partnership with 114 professional medical societies, organizations and institutions from around the world. (wikipedia.org)
  • antibiotics
  • In most cases, once pneumococcal pneumonia has been identified, doctors will prescribe antibiotics. (wikipedia.org)
  • Last 10 days I have severe pain behind left breast and chest and back pain sleeping over 16 hours a day and just feel terrible my question is: could I just keep getting worse and these antibiotics are not actually treating the pneumonia? (justanswer.com)
  • When pneumonia is diagnosed by medical history, a physical examination, and a chest X-ray, expectorated sputum samples are collected by a nurse before administering antibiotics. (biomedcentral.com)
  • No significant difference appears in treatment success rates between linezolid, glycopeptides, or appropriate beta-lactam antibiotics in the treatment of pneumonia. (wikipedia.org)
  • respiratory
  • We present an unusual case of a child with severe respiratory distress, on the brink of mechanical ventilation, due to a rapidly expanding pneumococcal pneumonia. (hindawi.com)
  • It has pneumococcal surface proteins that inhibit complement-mediated opsonization, and it secretes IgA1 protease that will destroy secretory IgA produced by the body and mediates its attachment to respiratory mucosa. (wikipedia.org)
  • No cases in humans have yet been reported but it is believed this is due to misdiagnosis and confusion with other rapidly progressive, life-threatening respiratory illnesses such as plague, influenza and pneumococcal pneumonia. (wikipedia.org)
  • mice
  • Mice deficient in the gp91 phox component of the phagocyte NADPH oxidase were studied after pneumococcal challenge. (pubmedcentralcanada.ca)
  • We investigated survival, lung bacterial burden, and cellular host responses in bronchoalveolar lavage fluids obtained from mice infected with pneumonia and treated with ceftriaxone, azithromycin, or both in combination. (pubmedcentralcanada.ca)
  • Griffith was sent pneumococci samples taken from patients throughout the country, amassed a large number, and would type-in other words classify-each pneumococci sample to search patterns of pneumonia epidemiology, and Griffith experimented on mice for improved understanding of its pathology. (wikipedia.org)
  • Injected subcutaneously with S form, mice succumbed to pneumonia and death within several days. (wikipedia.org)
  • When mice were injected with a mixture of heat-killed S and live R, however, pneumonia and death ensued. (wikipedia.org)
  • Penicillin
  • We describe failure of treatment of pneumococcal pneumonia in a 71-year-old man, who was allergic to penicillin and had a history of chronic obstructive pulmonary disease. (cdc.gov)
  • Seventy adult patients diagnosed with pneumococcal pneumonia based on an initial comprehensive assessment and treated with high-dose penicillin G at admission were included. (biomedcentral.com)
  • Patients aged 18 years or older who were admitted to the hospital for pneumonia and initially treated with high-dose penicillin G from April 2012 to May 2017 were included. (biomedcentral.com)
  • During the study period, 78 patients who had received high-dose penicillin G treatment for pneumonia were identified. (biomedcentral.com)
  • cause
  • However, the R form, lacking a capsule-its outer surface being cell wall-is relatively avirulent, and does not cause pneumonia as often. (wikipedia.org)
  • Pneumonia is also the leading cause of death in children less than five years of age in low income countries. (wikipedia.org)