• Huntington
  • Die Erkrankung Huntington s Chorea ist eine autosomal dominant vererbte Erkrankung, die gewöhnlich im mittleren Lebensabschnitt beginnt und unausweichlich zum Tode führt. (hu-berlin.de)
  • Bei Untersuchungen am Menschen wurde in drei Gehirnregionen von Postmortem-Gehirnen von Huntington s Chorea Patienten eine veränderte Expression von alpha1-Antitrypsin festgestellt. (hu-berlin.de)
  • Wenn gewährleistet werden kann, dass die Konzentration von alpha1-Antitrypsin und alphaB-Kristallin während Huntington s Chorea im Gewebe nicht absinkt, könnte dies vielleicht neuronalen Zelltod verhindern und somit bei der Verzögerung des Krankheitsverlaufs nutzbringend eingesetzt werden. (hu-berlin.de)
  • Huntington chorea - an inherited degenerative disorder of the cerebral cortex and corpus striatum. (thefreedictionary.com)
  • tics
  • In contrast to the abnormal movements of other movement disorders (for example, choreas, dystonias, myoclonus, and dyskinesias), the tics of Tourette's are temporarily suppressible, nonrhythmic, and often preceded by an unwanted premonitory urge. (wikipedia.org)
  • pregnancy
  • It is not an causal or pathologically distinct entity but a generic term for chorea of any cause starting during pregnancy. (wikipedia.org)
  • Acanthocytosis
  • The treatment to battle the disease chorea-acanthocytosis is completely symptomatic. (wikipedia.org)
  • Patients with chorea-acanthocytosis should undergo a cardiac evaluation every 5 years to look for cardiomyopathy. (wikipedia.org)
  • Online Mendelian Inheritance in Man (OMIM) 200150 "Chorea Acanthocytosis. (wikipedia.org)
  • Deep Brain Stimulation in Chorea Acanthocytosis. (wikipedia.org)
  • Neuromuscular involvement in chorea-acanthocytosis. (wikipedia.org)
  • Neuropathology of Chorea-Acanthocytosis. (wikipedia.org)
  • GeneReviews/NCBI/NIH/UW entry on Chorea-acanthocytosis "Chorea Acanthocytosis. (wikipedia.org)
  • The 'core' neuroacanthocytosis syndromes, in which acanthocytes are a typical feature, are chorea acanthocytosis and McLeod syndrome. (wikipedia.org)
  • In neuroacanthocytosis, acanthocytes are caused by protein but not lipid membrane abnormalities The 'core' neuroacanthocytosis syndromes are chorea acanthocytosis and McLeod syndrome. (wikipedia.org)
  • Strikingly, many people with chorea acanthocytosis uncontrollably bite their tongue, lips, and the inside of the mouth. (wikipedia.org)
  • Patients
  • citation needed] Drug treatment is indicated for patients with severe disabling chorea. (wikipedia.org)
  • Patients affected by aPL-related chorea have an increased risk of thrombosis and should receive antiplatelet or anticoagulant treatment. (frontiersin.org)
  • The drug's manufacturer, Prestwick Pharmaceuticals Inc, plans to file a New Drug Application with the FDA for tetrabenazine for use in the treatment of chorea in HD patients. (pharmacytimes.com)
  • antibodies
  • Chorea is a well-known but rare manifestation associated with immune system dysfunction and, particularly, with the presence of antiphospholipid antibodies (aPL). (frontiersin.org)
  • tetrabenazine
  • After 12 weeks, the chorea score for the tetrabenazine group had decreased by 5 points, whereas the scores for the placebo group had decreased by only 1.5 points. (pharmacytimes.com)