• TRPM8
  • Transient Receptor Potential cation channel, subfamily Melastatin, member 8 (TRPM8) is involved in detection of cold temperature, different noxious compounds and in execution of thermo- as well as chemo-sensitive responses at cellular levels. (peerj.com)
  • TRPM8 is a well-established non-selective cation channel and so far has been reported from several species, yet exclusively in vertebrates. (peerj.com)
  • For example, TRPM8-specific agonist-mediated cation influx via TRPM8 is pH-dependent. (peerj.com)
  • Transient receptor potential melastatin subtype 8 (TRPM8) is a mild coldā€sensing nonselective cation channel that is activated by menthol. (ahajournals.org)
  • channel
  • TRPM2 (Transient Receptor Potential Melastatin-2) expressed in endothelial cells (ECs) is a cation channel mediating Ca 2+ entry in response to intracellular generation of adenosine diphosphoribose (ADPR), the TRPM2 ligand. (ahajournals.org)