• acute
  • Occlusive intracoronary thrombus - a thrombus overlying an ulcerated or fissured stenotic plaque causes 90% of transmural acute myocardial infarctions . (factbites.com)
  • After extensive review of patient's clinical presentation, initial coronary angiography images and noninvasive cardiac imaging, it was predominantly felt that she likely had a horizontal fibrous band compressing the coronary segments and causing acute ischemia, injury, and electric instability. (ahajournals.org)
  • We present a case of acute MI, cardiogenic shock, and cardiac arrest caused not by this mechanism, but by embolisation of thrombotic material to the aortic root with transient complete occlusion of the left main stem (LMS) coronary artery. (biomedsearch.com)
  • In severe cases, acute rupture or erosion of atherosclerotic plaques lead to the rapid formation of intravascular thrombi, a process referred to atherothrombosis. (ahajournals.org)
  • The primary purpose of the electrocardiogram is to detect ischemia or acute coronary injury in broad, symptomatic emergency department populations. (wikipedia.org)
  • The 12 lead ECG is used to classify patients into one of three groups: those with ST segment elevation or new bundle branch block (suspicious for acute injury and a possible candidate for acute reperfusion therapy with thrombolytics or primary PCI), those with ST segment depression or T wave inversion (suspicious for ischemia), and those with a so-called non-diagnostic or normal ECG. (wikipedia.org)
  • anomaly
  • Most importantly, deep and long bridged segments are significantly more common in patients dying suddenly, suggesting a role for this anomaly in the clinical course and risk stratification of HCM. (ahajournals.org)
  • systolic
  • 05). Less severe levels of ischemia (n=17) resulted in significant stunning (percent systolic wall thickening, 38±4% of control) but no change in pCa 50 . (ahajournals.org)
  • sensitivity
  • For early detection of myocardial necrosis , sensitivity of this laboratory test is superior to that of the creatine kinase-MB (CK-MB). (factbites.com)
  • We conclude that the basis of stunning involves decreased cycling rates of myofibrillar cross-bridges and, after more severe ischemia, a reduction in myofilament Ca 2+ sensitivity. (ahajournals.org)
  • 15 Taken together, these results demonstrate that Ca 2+ sensitivity of myocardial tension is reduced after reperfusion, and this may account for the depressed contractile function associated with stunning. (ahajournals.org)
  • Ca 2+ sensitivity of isometric tension and the rate of cross-bridge cycling were assessed, since a reduction in either of these properties would likely decrease both tension and the amount of muscle shortening during an individual heartbeat. (ahajournals.org)
  • diagnosis
  • The appearance of cardiac markers in the circulation generally indicates myocardial necrosis and is a useful adjunct to diagnosis. (factbites.com)
  • Although very unusual we feel this case highlights an important differential in the diagnosis of anterolateral MI and images similar to those presented here are previously unreported in the literature. (biomedsearch.com)
  • Myocardial bridges: Overview of diagnosis and management. (stanford.edu)
  • severe cases
  • Characteristic symptoms include yellow discoloration of the skin or whites of the eyes, fever, abdominal pain, and in severe cases, low blood pressure and confusion. (wikipedia.org)
  • etiology
  • The etiology of ABS remains unclear, and ABS may be due to catecholamine-mediated myocardial stunning, coronary spasm, coronary emboli with spontaneous fibrinolysis, or microvascular dysfunction ( 1-5 ). (onlinejacc.org)
  • 6 7 Although the etiology of stunning is not fully understood, considerable evidence suggests that the formation of oxygen-derived free radicals and elevated cytosolic Ca 2+ during ischemia and early reperfusion contributes to the development of stunning. (ahajournals.org)
  • reduction
  • It is now known that hydrogen sulfide has cardioprotective effects in cases of ischemia related to its effects as an endogenous messenger molecule, primarily via its reduction of the rate of cellular metabolism. (wikipedia.org)
  • Detail
  • The cases are described in detail here, including all information available from the transplant center. (redorbit.com)
  • common
  • Deep MB ≥2mm was present in 25 out of 120 hearts (21%), and significantly more common in SD (21/82, 26%) than non-SD cases (4/38, 10%) (p=0.03). (ahajournals.org)
  • patient
  • In each case, a nephrologist was following up with the patient regularly. (redorbit.com)
  • In each case, the transplant team was unaware that the patient had sought an organ outside the United States until the patient requested posttransplant care. (redorbit.com)
  • injury
  • Now, the markers most widely used in detection of MI are MB subtype of the enzyme creatine kinase and cardiac troponins T and I as they are more specific for myocardial injury. (wikipedia.org)
  • function
  • To investigate the possibility that alterations in myofibrillar cross-bridge kinetics contribute to depressed function in stunning, maximum velocity of shortening (V o ) was measured in postischemic myocytes. (ahajournals.org)
  • The case of autotomy, for example, serves as a defensive function as the animal detaches a limb or tail to avoid capture. (wikipedia.org)